Glycoside Hydrolase Family 48

Activities in Familyreducing end-acting cellobiohydrolase (EC 3.2.1.176); endo-β-1,4-glucanase (EC 3.2.1.4); chitinase (EC 3.2.1.14)
Mechanism Inverting
ClanGH-M
3D Structure Status( α / α ) 6
Catalytic Nucleophile/BaseNot known
Catalytic Proton DonorGlu
Noteformerly known as cellulase family L. Some cellobiohydrolases of this family have been reported to act from the reducing ends of cellulose (EC 3.2.1.-), while others have been reported to operate from the non-reducing ends to liberate cellobiose or cellotriose or cellotetraose (EC 3.2.1.-). This family also contains endo-processive cellulases (EC 3.2.1.-), whose activity is hard to distinguish from that of cellobiohydrolases.
External resourcesCAZypedia; HOMSTRAD; PRINTS;
Commercial Enzyme Provider(s)NZYTech;
Statistics GenBank accession (1143); Uniprot accession (114); PDB accession (26); 3D entries (7); cryst (0)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 glycoside hydrolase family 48 protein, partial (Gh48) (fragment)   uncultured actinobacterium ART41354.1    
 glycoside hydrolase family 48 protein, partial (Gh48) (fragment)   uncultured actinobacterium ART41345.1    
 glycoside hydrolase family 48 protein, partial (Gh48) (fragment)   uncultured actinobacterium ART41362.1    
 glycoside hydrolase family 48 protein, partial (Gh48) (fragment)   uncultured actinobacterium ART41353.1    
 glycoside hydrolase family 48 protein, partial (Gh48) (fragment)   uncultured actinobacterium ART41356.1    
 glycoside hydrolase family 48 protein, partial (Gh48) (fragment)   uncultured actinobacterium ART41341.1    
 glycoside hydrolase family 48 protein, partial (Gh48) (fragment)   uncultured actinobacterium ART41360.1    
 glycoside hydrolase family 48 protein, partial (Gh48) (fragment)   uncultured actinobacterium ART41348.1    
 glycoside hydrolase family 48 protein, partial (Gh48) (fragment)   uncultured actinobacterium ART41339.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35763.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35744.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35745.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35718.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35754.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35714.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35720.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35698.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35705.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35729.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35740.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35770.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35759.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35707.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35735.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35696.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35710.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35702.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35724.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35708.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35772.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35726.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35764.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35736.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35746.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35741.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35715.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35753.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35706.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35699.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35727.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35769.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35732.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35749.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35723.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35758.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35756.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35737.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35730.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35711.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35703.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35725.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35742.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35709.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35761.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35768.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35752.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35733.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35700.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35722.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35738.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35717.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35731.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35748.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35765.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35716.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35757.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35712.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35755.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35719.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35697.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35743.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35767.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35704.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35774.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35721.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35762.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35760.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35713.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35728.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35739.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35701.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35771.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35734.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35747.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35766.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01261.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01266.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01267.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01268.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01270.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01271.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01272.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01273.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01275.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01277.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01279.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01280.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01281.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01282.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01283.1    
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