Glycoside Hydrolase Family 48

Activities in FamilyChitinase (EC 3.2.1.14);
Reducing end-acting cellobiohydrolase (EC 3.2.1.176);
Endo-β-1,4-glucanase (EC 3.2.1.4);
Cellobiohydrolase (EC 3.2.1.91);
Mechanism Inverting e
ClanGH-M
3D Structure Status( α / α ) 6 barrel
Catalytic Nucleophile/BaseNot known
Catalytic Proton DonorGlu
Noteformerly known as cellulase family L. Some cellobiohydrolases of this family have been reported to act from the reducing ends of cellulose (EC 3.2.1.-), while others have been reported to operate from the non-reducing ends to liberate cellobiose or cellotriose or cellotetraose (EC 3.2.1.-). This family also contains endo-processive cellulases (EC 3.2.1.-), whose activity is hard to distinguish from that of cellobiohydrolases.
External resourcesCAZypedia; HOMSTRAD; PRINTS;
Commercial Enzyme Provider(s)NZYTech;
Statistics GenBank accession (1839); Uniprot accession (24); PDB accession (30); 3D entries (11); cryst (0)
| 1 | ... | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | ... | 17 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Cel48A (fragment)   Ruminococcus albus AJA33593.1    
 Cel48A (fragment)   Ruminococcus albus AJA33594.1    
 Cel48A (fragment)   Ruminococcus albus AJA33597.1    
 Cel48A (fragment)   Ruminococcus albus AJA33598.1    
 Cel48A (fragment)   Ruminococcus albus AJA33599.1    
 Cel48A (fragment)   Ruminococcus albus AJA33600.1    
 Cel48A (fragment)   Ruminococcus albus AJA33603.1    
 Cel48A (fragment)   Ruminococcus albus AJA33604.1    
 Cel48A (fragment)   Ruminococcus albus AJA33605.1    
 Cel48A (fragment)   Ruminococcus albus AJA33606.1    
 Cel48A (fragment)   Ruminococcus albus AJA33591.1    
 Cel48A (fragment)   Ruminococcus albus AJA33592.1    
 Cel48A (fragment)   Ruminococcus albus AJA33595.1    
 Cel48A (fragment)   Ruminococcus albus AJA33596.1    
 Cel48A (fragment)   Ruminococcus albus AJA33601.1    
 Cel48A (fragment)   Ruminococcus albus AJA33602.1    
 Cel48B (CBP2) (Cel48B)   Ruminococcus albus 20 CAS03459.1    
 Rumal_2606   Ruminococcus albus 7 = DSM 20455 ADU23081.1    
 processive endocellulase (Cel48A)   Ruminococcus albus 8 AAR01217.1    
 Cel48A (fragment)   Ruminococcus albus B199 AJA33607.1    
 cellulase (Cel48A)   Ruminococcus albus F40 BAJ05814.1    
 cellobiohydrolase (GH48A;RUM_11720) (Cel48A)   Ruminococcus champanellensis 18P13 = JCM 17042 CBL17316.1    
 GCM10017745_64960   Saccharothrix mutabilis subsp. capreolus JCM 4248 BFE53069.1    
 IOD16_11285   Saccharothrix sp. 6-C QQQ78949.1    
 L3Q67_29515   Saccharothrix sp. AJ9571 UJW29360.1    
 EKG83_34475   Saccharothrix syringae NRRL B-16468 QFZ21834.1    
 Sare_3180   Salinispora arenicola CNS-205 ABV98987.1    
 Strop_2957   Salinispora tropica CNB-440 ABP55395.1    
 O7608_18515   Solwaraspora sp. WMMA2056 WJK38495.1    
 O7553_14530   Solwaraspora sp. WMMA2059 WBC00012.1    
 O7610_09070   Solwaraspora sp. WMMA2065 WJK36478.1    
 O7543_02840   Solwaraspora sp. WMMA2080 WBC21442.1    
 O7623_02075   Solwaraspora sp. WMMD791 WFE28018.1    
 O7621_22795   Solwaraspora sp. WMMD937 WFE20685.1    
 GXP74_19885   Streptacidiphilus sp. P02-A3a QMU70153.1    
 GXP74_21470   Streptacidiphilus sp. P02-A3a QMU70397.1    
 EKD16_23830 (CbhB)   Streptomonospora litoralis M2 QBI56512.1    
 OUQ99_16320   Streptomonospora nanhaiensis 12A09 WAE70809.1    
 DMT42_31570   Streptomyces actuosus ATCC 25421 AWT46392.1    
 K1J60_07350   Streptomyces akebiae MG28 QYX76349.1    
 SAM23877_6250   Streptomyces ambofaciens ATCC 23877 AKZ59295.1    
 SAM40697_5607   Streptomyces ambofaciens DSM 40697 ANB09563.1    
 QR300_27235   Streptomyces antimycoticus FIM95-F1 WJD99382.1    
 HKX69_05255   Streptomyces argyrophyllae Jing01 QJS08999.1    
 G9272_36365   Streptomyces asoensis H2S5 QJT05106.1    
 CD934_04280   Streptomyces asterosporus DSM 41452 QDI67973.1    
 O1Q96_32730   Streptomyces aurantiacus Qhu-M197 WAU84036.1    
 BV401_17865   Streptomyces autolyticus CGMCC0516 AQA12037.1    
 SAV1855 (GuxA3)   Streptomyces avermitilis MA-4680 = NBRC 14893 BAC69566.1
NP_823031.1
   
 SAVMC3_22070   Streptomyces avermitilis MC3 BBJ49578.1    
 SBI_06901 (Guxa3)   Streptomyces bingchenggensis BCW-1 ADI10021.1    
 EJC51_44365   Streptomyces brunneus CR22 AZP22498.1    
 EJC51_38245   Streptomyces brunneus CR22 AZP21412.1    
 IHE65_06880   Streptomyces caniscabiei ID-03-3A WEO22891.1    
 OG925_10885   Streptomyces canus NBC_01585 WSD84760.1    
 PYS65_05120   Streptomyces sp. HUAS 5 WGD39569.1    
 NRO40_10375   Streptomyces changanensis HL-66 UUS31204.1    
 CP983_07820   Streptomyces chartreusis ATCC 14922 QEV66588.1    
 HUT05_09125   Streptomyces chartreusis NA02069 QKZ17495.1    
 STRCI_006664   Streptomyces cinnabarinus DSM 40467 WAZ25188.1    
 SCO6546 (SC5C7.31c)   Streptomyces coelicolor A3(2) CAA20643.1
NP_630627.1
   
 FQ762_33785   Streptomyces coelicolor A3(2) CFB_NBC_0001 QFI46341.1    
 JCM4020_66930   Streptomyces coelicolor JCM 4020 BDD76073.1    
 HCU77_32960   Streptomyces coelicolor M1154/pAMX4/pGP1416 QKN69863.1    
 RE436_32800   Streptomyces coelicolor M22 WMT36924.1    
 CP976_36070   Streptomyces coeruleorubidus ATCC 13740 QEV29002.1    
 PV963_37670   Streptomyces coeruleorubidus DM WDV55674.1    
 R5U08_02380   Streptomyces coeruleorubidus WT-48 WOT33051.1    
 RFN52_33375   Streptomyces collinus CGMCC 4.1623 WMX67983.1    
 HGI09_09480   Streptomyces collinus L2 UJA13649.1    
 HGI10_54620   Streptomyces collinus SQ UJA11485.1    
 B446_30095   Streptomyces collinus Tu 365 AGS72823.1    
 QU709_06435   Streptomyces coralus SX92 WLW51019.1    
 EJ357_39170   Streptomyces cyaneochromogenes MK-45 AZQ38730.1    
 TU94_27795   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP04698.1    
 S1361_32540 (Cbhb2)   Streptomyces cyanogenus S136 QTE02106.1    
 N8I84_32595   Streptomyces cynarae HUAS 13-4 UXY22917.1    
 D9753_05760   Streptomyces dangxiongensis Z022 AYN38508.1    
 BN159_1887 (CbhB)   Streptomyces davaonensis JCM 4913 CCK26266.1    
 L3078_37885   Streptomyces deccanensis KCTC 19241 ULR54592.1    
 NEH16_27770   Streptomyces drozdowiczii MDA8-470 UZK58663.1    
 PS783_31655   Streptomyces enissocaesilis NBF 715 WDI21880.1    
 IM697_29865   Streptomyces ferrugineus CCTCC AA2014009 QOV34324.1    
 F0344_33745   Streptomyces finlayi NBSH44 QNE78898.1    
 CP974_10385   Streptomyces fradiae ATCC 10745 = DSM 40063 QEV12369.1    
 RYQ63_04810   Streptomyces fradiae FIMYZ-003 WOI59283.1    
 J5J01_13125   Streptomyces fradiae ZXY017 UQS32391.1    
 CNQ36_27485   Streptomyces fungicidicus TXX3120 AYL38815.1    
 CP966_30055   Streptomyces galilaeus ATCC 14969 QEU69048.1    
 H4W23_33575   Streptomyces gardneri ATCC 15439 QPK49085.1    
 IAG43_28680   Streptomyces genisteinicus CRPJ-33 QNP66512.1    
 SGLAU_27580 (CbhB)   Streptomyces glaucescens GLA.O AIS01454.1    
 GCM10017557_13610   Streptomyces glomeroaurantiacus JCM 4677 BCL26502.1    
 SGFS_029460   Streptomyces graminofaciens A-8890 BBC31652.1    
 SGFS_100520   Streptomyces graminofaciens A-8890 BBC38758.1    
 V9K83_05430   Streptomyces griseoaurantiacus XQ-29 WWY83684.1    
 HEP81_00533 (CbhB)   Streptomyces griseofuscus DSM 40191 QNT90869.1    
 UBV09_28670   Streptomyces griseoincarnatus HNS054 WPW22412.1    
 DWG14_00672 (Cbhb_1)   Streptomyces griseorubiginosus 3E-1 AYC36462.1    
 DWG14_01662 (Cbhb_2)   Streptomyces griseorubiginosus 3E-1 AYC37444.1    
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