Glycoside Hydrolase Family 48

Activities in Familyreducing end-acting cellobiohydrolase (EC 3.2.1.176); endo-β-1,4-glucanase (EC 3.2.1.4); chitinase (EC 3.2.1.14)
Mechanism Inverting
ClanGH-M
3D Structure Status( α / α ) 6
Catalytic Nucleophile/BaseNot known
Catalytic Proton DonorGlu
Noteformerly known as cellulase family L. Some cellobiohydrolases of this family have been reported to act from the reducing ends of cellulose (EC 3.2.1.-), while others have been reported to operate from the non-reducing ends to liberate cellobiose or cellotriose or cellotetraose (EC 3.2.1.-). This family also contains endo-processive cellulases (EC 3.2.1.-), whose activity is hard to distinguish from that of cellobiohydrolases.
External resourcesCAZypedia; HOMSTRAD; PRINTS;
Commercial Enzyme Provider(s)NZYTech;
Statistics GenBank accession (1186); Uniprot accession (114); PDB accession (27); 3D entries (8); cryst (0)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35700.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35722.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35738.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35717.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35731.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35748.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35765.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35716.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35757.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35712.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35755.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35719.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35697.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35743.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35767.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35704.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35774.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35721.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35762.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35760.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35713.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35728.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35739.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35701.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35771.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35734.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35747.1    
 glycoside hydrolase familiy 48, partial (fragment)   uncultured actinobacterium AJR35766.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01261.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01266.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01267.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01268.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01270.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01271.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01272.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01273.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01275.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01277.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01279.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01280.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01281.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01282.1    
 glycosyl hydrolase family 48 protein, partial (Cel48) (fragment)   uncultured actinomycete AIL01283.1    
 ORF (fragment)   uncultured actinomycete AIL01260.1    
 ORF (fragment)   uncultured actinomycete AIL01262.1    
 ORF (fragment)   uncultured actinomycete AIL01263.1    
 ORF (fragment)   uncultured actinomycete AIL01264.1    
 ORF (fragment)   uncultured actinomycete AIL01265.1    
 ORF (fragment)   uncultured actinomycete AIL01269.1    
 ORF (fragment)   uncultured actinomycete AIL01274.1    
 ORF (fragment)   uncultured actinomycete AIL01276.1    
 ORF (fragment)   uncultured actinomycete AIL01278.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58599.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58585.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58576.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58598.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58602.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58588.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58592.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58589.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58582.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58579.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58574.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58608.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58617.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58600.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58575.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58609.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58593.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58595.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58612.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58605.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58603.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58587.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58591.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58615.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58584.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58610.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58614.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58578.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58601.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58573.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58594.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58606.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58571.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58596.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58604.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58586.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58572.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58611.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58613.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58597.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58581.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58583.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58590.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58580.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58607.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58616.1    
 glycoside hydrolase family 48 cellulase, partial (Cel48) (fragment)   uncultured bacterium ANK58577.1    
 glycosyl hydrolase family 48 protein, partial (fragment)   uncultured bacterium ANN23794.1    
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