| Known Activities | reducing end-acting cellobiohydrolase (EC 3.2.1.176); endo-β-1,4-glucanase (EC 3.2.1.4); chitinase (EC 3.2.1.14) |
|---|---|
| Mechanism | Inverting |
| Clan | GH-M |
| 3D Structure Status | ( α / α ) 6 |
| Catalytic Nucleophile/Base | Not known |
| Catalytic Proton Donor | Glu |
| Note | formerly known as cellulase family L. Some cellobiohydrolases of this family have been reported to act from the reducing ends of cellulose (EC 3.2.1.-), while others have been reported to operate from the non-reducing ends to liberate cellobiose or cellotriose or cellotetraose (EC 3.2.1.-). This family also contains endo-processive cellulases (EC 3.2.1.-), whose activity is hard to distinguish from that of cellobiohydrolases. |
| External resources | CAZypedia; HOMSTRAD; InterPro; PFAM; PRINTS; |
| Commercial Enzyme Provider(s) | NZYTech; |
| Statistics | GenBank accession (175); Uniprot accession (113); PDB accession (11); 3D entries (2); cryst (0) |
Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.