Glycoside Hydrolase Family 48

Known Activitiesreducing end-acting cellobiohydrolase (EC; endo-β-1,4-glucanase (EC; chitinase (EC
Mechanism Inverting
3D Structure Status( α / α ) 6
Catalytic Nucleophile/BaseNot known
Catalytic Proton DonorGlu
Noteformerly known as cellulase family L. Some cellobiohydrolases of this family have been reported to act from the reducing ends of cellulose (EC 3.2.1.-), while others have been reported to operate from the non-reducing ends to liberate cellobiose or cellotriose or cellotetraose (EC 3.2.1.-). This family also contains endo-processive cellulases (EC 3.2.1.-), whose activity is hard to distinguish from that of cellobiohydrolases.
External resourcesCAZypedia; HOMSTRAD; PRINTS;
Commercial Enzyme Provider(s)NZYTech;
Statistics GenBank accession (887); Uniprot accession (114); PDB accession (25); 3D entries (7); cryst (0)

Last update: 2015-11-25 © Copyright 1998-2015
AFMB - CNRS - Université d'Aix-Marseille