| Activities in Family | reducing end-acting cellobiohydrolase (EC 3.2.1.176); endo-β-1,4-glucanase (EC 3.2.1.4); chitinase (EC 3.2.1.14); cellobiohydrolase (EC 3.2.1.91) |
|---|---|
| Mechanism | Inverting e |
| Clan | GH-M |
| 3D Structure Status | ( α / α ) 6 barrel |
| Catalytic Nucleophile/Base | Not known |
| Catalytic Proton Donor | Glu |
| Note | formerly known as cellulase family L. Some cellobiohydrolases of this family have been reported to act from the reducing ends of cellulose (EC 3.2.1.-), while others have been reported to operate from the non-reducing ends to liberate cellobiose or cellotriose or cellotetraose (EC 3.2.1.-). This family also contains endo-processive cellulases (EC 3.2.1.-), whose activity is hard to distinguish from that of cellobiohydrolases. |
| External resources | CAZypedia; HOMSTRAD; PRINTS; |
| Commercial Enzyme Provider(s) | NZYTech; |
| Statistics | GenBank accession (1686); Uniprot accession (24); PDB accession (30); 3D entries (11); cryst (0) |