Glycoside Hydrolase Family 48

Known Activitiesendoglucanase (EC 3.2.1.4); chitinase (EC 3.2.1.14); cellobiohydrolase (EC 3.2.1.91); endo-processive cellulases (EC 3.2.1.-); [reducing end] cellobiohydrolase (3.2.1.-)
Mechanism Inverting
ClanGH-M
3D Structure Status( α / α ) 6
Catalytic Nucleophile/BaseNot known
Catalytic Proton DonorGlu
Noteformerly known as cellulase family L. Some cellobiohydrolases of this family have been reported to act from the reducing ends of cellulose (EC 3.2.1.-), while others have been reported to operate from the non-reducing ends to liberate cellobiose or cellotriose or cellotetraose (EC 3.2.1.-). This family also contains endo-processive cellulases (EC 3.2.1.-), whose activity is hard to distinguish from that of cellobiohydrolases.
External resourcesHOMSTRAD; InterPro; PFAM; PRINTS;
Statistics GenBank accession (90); Uniprot accession (36); PDB accession (13); 3D entries (2); cryst (0)