GlycosylTransferase Family 104

Activities in FamilydTDP-β-L-Rhap : arginine α-L-rhamnosyltransferase (EC 2.4.1.-)
Mechanism Inverting
NoteLassak et al. identified EarP as EF-P arginine R32 specific rhamnosyl transferase in Shewanella oneidensis using dTDP-b-L-rhamnose as donor substrate (PMID=25686373). The results of this study were subsequently confirmed for Pseudomonas aeruginosa (PMID=26060278), Pseudomonas putida (PMID=28951478) and Neisseria meningitidis (PMID=26840407). In 2016, it has been shown for S. oneidensis (PMID=28451135) and P. aeruginosa (PMID=28451332) that the enzyme is an inverting glycosyltransferase, thus mediating the formation of an a-L-rhamnosidic linkage. A structural basis for the arginine glycosylation reaction was provided by Krafczyk, Macosek and coworkers by having solved the crystal structure of the GT-B folding EarP from P. putida and an accompanying biochemical analysis of the enzyme (PMID=28951478).
Statistics GenBank accession (2404); Uniprot accession (0); PDB accession (9); 3D entries (3); cryst (0)
All (2396) Bacteria (2396) Structure (3) Characterized (4)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 24 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 FYA58_15725 (EarP)   Bordetella holmesii H249 QGE44275.1    
 FYA59_15730 (EarP)   Bordetella holmesii H250 QGE41028.1    
 FYA61_15775 (EarP)   Bordetella holmesii H318 QGE33619.1    
 FYA62_15720 (EarP)   Bordetella holmesii H319 QGE30369.1    
 FYA63_15730 (EarP)   Bordetella holmesii H336 QGE27121.1    
 FYA64_15735 (EarP)   Bordetella holmesii H359 QGE23875.1    
 FYA65_15735 (EarP)   Bordetella holmesii H370 QGE20626.1    
 FYA66_15735 (EarP)   Bordetella holmesii H385 QGE17380.1    
 FYA67_15730 (EarP)   Bordetella holmesii H387 QGE14136.1    
 FYA68_15740 (EarP)   Bordetella holmesii H400 QGE10897.1    
 FYA69_15750 (EarP)   Bordetella holmesii H401 QGE07641.1    
 FYA72_15730 (EarP)   Bordetella holmesii H557 QGD96055.1    
 H558_03600   Bordetella holmesii H558 AMD44657.1    
 FYA73_15735 (EarP)   Bordetella holmesii H558 QRE71508.1    
 FYA74_15730 (EarP)   Bordetella holmesii H572 QGD92803.1    
 FYA77_15715 (EarP)   Bordetella holmesii H610 QGD81230.1    
 FYA78_15735 (EarP)   Bordetella holmesii H619 QGD77988.1    
 FYA79_15735 (EarP)   Bordetella holmesii H620 QGD74729.1    
 FYA80_15735 (EarP)   Bordetella holmesii H628 QGD71487.1    
 FYA81_15730 (EarP)   Bordetella holmesii H629 QGD68229.1    
 FYA82_15720 (EarP)   Bordetella holmesii H635 QGD64982.1    
 FYA83_15725 (EarP)   Bordetella holmesii H641 QGD61742.1    
 FYA84_15730 (EarP)   Bordetella holmesii H713 QGD58506.1    
 FYA87_15735 (EarP)   Bordetella holmesii H719 QGD52420.1    
 FYA88_15720 (EarP)   Bordetella holmesii H807 QGD49179.1    
 FYA89_15735 (EarP)   Bordetella holmesii H808 QGD45945.1    
 FYA91_15735 (EarP)   Bordetella holmesii H862 QGD39745.1    
 FYA92_15740 (EarP)   Bordetella holmesii H863 QGD36503.1    
 FYA93_15740 (EarP)   Bordetella holmesii H869 QGD33252.1    
 BBB42_15405   Bordetella holmesii H903 AOB36756.1    
 FYA94_15725 (EarP)   Bordetella holmesii I100 QGD30003.1    
 FYA98_15715 (EarP)   Bordetella holmesii I265 QGD12873.1    
 FYB13_15725 (EarP)   Bordetella holmesii J102 QGC63706.1    
 FYB19_15735 (EarP)   Bordetella holmesii J168 QGC43794.1    
 FYB43_15725 (EarP)   Bordetella holmesii J312 QGB65242.1    
 FYB57_15730 (EarP)   Bordetella holmesii J708 QGB15996.1    
 FYB59_15725 (EarP)   Bordetella holmesii J712 QGB08601.1    
 FYB63_15660 (EarP)   Bordetella holmesii J790 QJP63913.1    
 FYA36_15665 (EarP)   Bordetella holmesii J862 QJP54229.1    
 BPP2391   Bordetella parapertussis 12822 CAE37688.1    
 CWR63_12165   Bordetella parapertussis A005 AZW48818.1    
 B7P01_12160   Bordetella parapertussis A747 AWQ01160.1    
 CWR58_12180   Bordetella parapertussis B144 AZW39972.1    
 CWR59_12165   Bordetella parapertussis B149 AZW52979.1    
 CWR60_12175   Bordetella parapertussis B160 AZW57142.1    
 CWR62_12160   Bordetella parapertussis B271 AZW35786.1    
 B7P09_12160   Bordetella parapertussis B337 AWP96999.1    
 NB2BOR_18100   Bordetella parapertussis Bpp01 BBH98227.1    
 BN117_1544   Bordetella parapertussis Bpp5 CCJ48877.1    
 J3Q23_10155 (EarP)   Bordetella parapertussis CIDM-BPP2 QSY76480.1    
 B7P05_12160   Bordetella parapertussis D577 AWP89496.1    
 B7O99_09890   Bordetella parapertussis E738 AWP70491.1    
 B2B93_12150   Bordetella parapertussis E762 QBS61667.1    
 B2B88_12165   Bordetella parapertussis E843 QBS57517.1    
 CS346_12160   Bordetella parapertussis F585 AZW26677.1    
 FYA49_09915 (EarP)   Bordetella parapertussis H100 QGE74118.1    
 FYA50_12210 (EarP)   Bordetella parapertussis H101 QGE70374.1    
 FYA51_12205 (EarP)   Bordetella parapertussis H102 QGE66209.1    
 FYA53_12215 (EarP)   Bordetella parapertussis H104 QGE62043.1    
 FYA54_12210 (EarP)   Bordetella parapertussis H105 QGE57890.1    
 FYA56_09915 (EarP)   Bordetella parapertussis H242 QGE50059.1    
 FYA60_12205 (EarP)   Bordetella parapertussis H314 QGE36582.1    
 FYA70_12205 (EarP)   Bordetella parapertussis H554 QGE03177.1    
 FYA71_09915 (EarP)   Bordetella parapertussis H555 QGD98592.1    
 FYA75_09915 (EarP)   Bordetella parapertussis H580 QGD87931.1    
 FYA76_12205 (EarP)   Bordetella parapertussis H581 QGD84188.1    
 BBB43_12065   Bordetella parapertussis H904 AOB39488.1    
 FYA95_09915 (EarP)   Bordetella parapertussis I133 QGD25128.1    
 FYA96_12210 (EarP)   Bordetella parapertussis I139 QGD21384.1    
 FYA97_12215 (EarP)   Bordetella parapertussis I143 QGD17217.1    
 FYA99_08875 (EarP)   Bordetella parapertussis I267 QGD07832.1    
 FYB01_09915 (EarP)   Bordetella parapertussis I288 QGD03832.1    
 FYB02_09915 (EarP)   Bordetella parapertussis I301 QGC99671.1    
 FYB03_12210 (EarP)   Bordetella parapertussis I308 QGC95930.1    
 FYB04_09915 (EarP)   Bordetella parapertussis I325 QGC91342.1    
 FYB05_09915 (EarP)   Bordetella parapertussis I326 QGC87167.1    
 B7P06_09895   Bordetella parapertussis I440 AWP62993.1    
 FYB06_12210 (EarP)   Bordetella parapertussis I457 QGC83325.1    
 FYB07_12210 (EarP)   Bordetella parapertussis I458 QGC79158.1    
 FYB09_12210 (EarP)   Bordetella parapertussis I768 QGC74994.1    
 FYB11_12210 (EarP)   Bordetella parapertussis I962 QGC70830.1    
 FYB12_09915 (EarP)   Bordetella parapertussis J069 QGC66241.1    
 FYB14_09915 (EarP)   Bordetella parapertussis J116 QGC58825.1    
 FYB15_09915 (EarP)   Bordetella parapertussis J156 QGC54665.1    
 FYB16_09915 (EarP)   Bordetella parapertussis J158 QGC50498.1    
 FYB17_09915 (EarP)   Bordetella parapertussis J166 QGC46331.1    
 FYB21_12210 (EarP)   Bordetella parapertussis J216 QRE67057.1    
 FYB22_09915 (EarP)   Bordetella parapertussis J217 QGC38917.1    
 FYB24_09915 (EarP)   Bordetella parapertussis J219 QGC34754.1    
 FYB25_08160 (EarP)   Bordetella parapertussis J220 QGC30343.1    
 FYB26_09915 (EarP)   Bordetella parapertussis J221 QGC26498.1    
 FYB27_09915 (EarP)   Bordetella parapertussis J278 QGC22333.1    
 FYB28_09915 (EarP)   Bordetella parapertussis J279 QGC18167.1    
 FYB29_12210 (EarP)   Bordetella parapertussis J280 QGC13957.1    
 FYB30_09915 (EarP)   Bordetella parapertussis J281 QGC09369.1    
 FYB31_09915 (EarP)   Bordetella parapertussis J282 QGC05206.1    
 FYB33_12210 (EarP)   Bordetella parapertussis J284 QGC01462.1    
 FYB35_09915 (EarP)   Bordetella parapertussis J287 QGB96875.1    
 FYB36_09915 (EarP)   Bordetella parapertussis J289 QGB92712.1    
 FYB37_09915 (EarP)   Bordetella parapertussis J290 QGB88554.1    
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