GlycosylTransferase Family 104

Activities in FamilydTDP-β-L-Rhap : arginine α-L-rhamnosyltransferase (EC 2.4.1.-)
Mechanism Inverting
NoteLassak et al. identified EarP as EF-P arginine R32 specific rhamnosyl transferase in Shewanella oneidensis using dTDP-b-L-rhamnose as donor substrate (PMID=25686373). The results of this study were subsequently confirmed for Pseudomonas aeruginosa (PMID=26060278), Pseudomonas putida (PMID=28951478) and Neisseria meningitidis (PMID=26840407). In 2016, it has been shown for S. oneidensis (PMID=28451135) and P. aeruginosa (PMID=28451332) that the enzyme is an inverting glycosyltransferase, thus mediating the formation of an a-L-rhamnosidic linkage. A structural basis for the arginine glycosylation reaction was provided by Krafczyk, Macosek and coworkers by having solved the crystal structure of the GT-B folding EarP from P. putida and an accompanying biochemical analysis of the enzyme (PMID=28951478).
Statistics GenBank accession (2176); Uniprot accession (0); PDB accession (9); 3D entries (3); cryst (0)
All (2172) Bacteria (2172) Structure (3) Characterized (4)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 22 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CWR63_12165   Bordetella parapertussis A005 AZW48818.1    
 B7P01_12160   Bordetella parapertussis A747 AWQ01160.1    
 CWR58_12180   Bordetella parapertussis B144 AZW39972.1    
 CWR59_12165   Bordetella parapertussis B149 AZW52979.1    
 CWR60_12175   Bordetella parapertussis B160 AZW57142.1    
 CWR62_12160   Bordetella parapertussis B271 AZW35786.1    
 B7P09_12160   Bordetella parapertussis B337 AWP96999.1    
 NB2BOR_18100   Bordetella parapertussis Bpp01 BBH98227.1    
 BN117_1544   Bordetella parapertussis Bpp5 CCJ48877.1    
 B7P05_12160   Bordetella parapertussis D577 AWP89496.1    
 B7O99_09890   Bordetella parapertussis E738 AWP70491.1    
 B2B93_12150   Bordetella parapertussis E762 QBS61667.1    
 B2B88_12165   Bordetella parapertussis E843 QBS57517.1    
 CS346_12160   Bordetella parapertussis F585 AZW26677.1    
 FYA49_09915 (EarP)   Bordetella parapertussis H100 QGE74118.1    
 FYA50_12210 (EarP)   Bordetella parapertussis H101 QGE70374.1    
 FYA51_12205 (EarP)   Bordetella parapertussis H102 QGE66209.1    
 FYA53_12215 (EarP)   Bordetella parapertussis H104 QGE62043.1    
 FYA54_12210 (EarP)   Bordetella parapertussis H105 QGE57890.1    
 FYA56_09915 (EarP)   Bordetella parapertussis H242 QGE50059.1    
 FYA60_12205 (EarP)   Bordetella parapertussis H314 QGE36582.1    
 FYA70_12205 (EarP)   Bordetella parapertussis H554 QGE03177.1    
 FYA71_09915 (EarP)   Bordetella parapertussis H555 QGD98592.1    
 FYA75_09915 (EarP)   Bordetella parapertussis H580 QGD87931.1    
 FYA76_12205 (EarP)   Bordetella parapertussis H581 QGD84188.1    
 BBB43_12065   Bordetella parapertussis H904 AOB39488.1    
 FYA95_09915 (EarP)   Bordetella parapertussis I133 QGD25128.1    
 FYA96_12210 (EarP)   Bordetella parapertussis I139 QGD21384.1    
 FYA97_12215 (EarP)   Bordetella parapertussis I143 QGD17217.1    
 FYA99_08875 (EarP)   Bordetella parapertussis I267 QGD07832.1    
 FYB01_09915 (EarP)   Bordetella parapertussis I288 QGD03832.1    
 FYB02_09915 (EarP)   Bordetella parapertussis I301 QGC99671.1    
 FYB03_12210 (EarP)   Bordetella parapertussis I308 QGC95930.1    
 FYB04_09915 (EarP)   Bordetella parapertussis I325 QGC91342.1    
 FYB05_09915 (EarP)   Bordetella parapertussis I326 QGC87167.1    
 B7P06_09895   Bordetella parapertussis I440 AWP62993.1    
 FYB06_12210 (EarP)   Bordetella parapertussis I457 QGC83325.1    
 FYB07_12210 (EarP)   Bordetella parapertussis I458 QGC79158.1    
 FYB09_12210 (EarP)   Bordetella parapertussis I768 QGC74994.1    
 FYB11_12210 (EarP)   Bordetella parapertussis I962 QGC70830.1    
 FYB12_09915 (EarP)   Bordetella parapertussis J069 QGC66241.1    
 FYB14_09915 (EarP)   Bordetella parapertussis J116 QGC58825.1    
 FYB15_09915 (EarP)   Bordetella parapertussis J156 QGC54665.1    
 FYB16_09915 (EarP)   Bordetella parapertussis J158 QGC50498.1    
 FYB17_09915 (EarP)   Bordetella parapertussis J166 QGC46331.1    
 FYB22_09915 (EarP)   Bordetella parapertussis J217 QGC38917.1    
 FYB24_09915 (EarP)   Bordetella parapertussis J219 QGC34754.1    
 FYB25_08160 (EarP)   Bordetella parapertussis J220 QGC30343.1    
 FYB26_09915 (EarP)   Bordetella parapertussis J221 QGC26498.1    
 FYB27_09915 (EarP)   Bordetella parapertussis J278 QGC22333.1    
 FYB28_09915 (EarP)   Bordetella parapertussis J279 QGC18167.1    
 FYB29_12210 (EarP)   Bordetella parapertussis J280 QGC13957.1    
 FYB30_09915 (EarP)   Bordetella parapertussis J281 QGC09369.1    
 FYB31_09915 (EarP)   Bordetella parapertussis J282 QGC05206.1    
 FYB33_12210 (EarP)   Bordetella parapertussis J284 QGC01462.1    
 FYB35_09915 (EarP)   Bordetella parapertussis J287 QGB96875.1    
 FYB36_09915 (EarP)   Bordetella parapertussis J289 QGB92712.1    
 FYB37_09915 (EarP)   Bordetella parapertussis J290 QGB88554.1    
 FYB38_09915 (EarP)   Bordetella parapertussis J291 QGB84389.1    
 FYB39_09915 (EarP)   Bordetella parapertussis J292 QGB80223.1    
 FYB40_19110 (EarP)   Bordetella parapertussis J293 QGB77735.1    
 FYB41_11170 (EarP)   Bordetella parapertussis J297 QGB72206.1    
 FYB42_09920 (EarP)   Bordetella parapertussis J307 QGB67784.1    
 FYB44_12210 (EarP)   Bordetella parapertussis J324 QGB60796.1    
 FYB45_09915 (EarP)   Bordetella parapertussis J326 QGB56207.1    
 FYB46_09915 (EarP)   Bordetella parapertussis J327 QGB52022.1    
 FYB47_09915 (EarP)   Bordetella parapertussis J328 QGB47857.1    
 FYB48_09915 (EarP)   Bordetella parapertussis J396 QGB43692.1    
 FYB49_09915 (EarP)   Bordetella parapertussis J456 QGB39524.1    
 FYB50_09915 (EarP)   Bordetella parapertussis J593 QGB35360.1    
 FYB51_09915 (EarP)   Bordetella parapertussis J599 QGB31195.1    
 FYB52_09915 (EarP)   Bordetella parapertussis J602 QGB27031.1    
 FYB53_12205 (EarP)   Bordetella parapertussis J611 QGB23292.1    
 FYB55_09915 (EarP)   Bordetella parapertussis J676 QGB18542.1    
 FYB56_09870 (EarP)   Bordetella parapertussis J677 QJP66434.1    
 FYB58_09915 (EarP)   Bordetella parapertussis J711 QGB11129.1    
 FYB61_09865 (EarP)   Bordetella parapertussis J778 QJP59020.1    
 FYB62_12210 (EarP)   Bordetella parapertussis J786 QGB04142.1    
 FYB64_12205 (EarP)   Bordetella parapertussis J792 QGA99977.1    
 FYB65_09915 (EarP)   Bordetella parapertussis J835 QGA95389.1    
 FYB66_09915 (EarP)   Bordetella parapertussis J859 QGA91150.1    
 NCTC10520_02076   Bordetella parapertussis NCTC10520 SQH17184.1    
 NCTC10522_02544   Bordetella parapertussis NCTC10522 VTR35794.1    
 NCTC10524_03504   Bordetella parapertussis NCTC10524 VEF53501.1    
 Q425_15670   Bordetella pertussis 137 AJB26274.1    
 BN118_1020   Bordetella pertussis 18323 CCJ62445.1    
 AL474_04545   Bordetella pertussis ATCC:BAA-1335D-5 AMG21806.1    
 B1838_1990   Bordetella pertussis B1838 ALH49409.1    
 B1865_1784   Bordetella pertussis B1865 ALH52682.1    
 B1917_1785   Bordetella pertussis B1917 AIW92171.1    
 B1920_1865   Bordetella pertussis B1920 AIW95725.1    
 BBB38_10270   Bordetella pertussis B202 ANT93366.1    
 ADU61_07860   Bordetella pertussis B203 ANT89313.1    
 B3405_1858   Bordetella pertussis B3405 ALH56228.1    
 B3582_1785   Bordetella pertussis B3582 ALH59607.1    
 B3585_2608   Bordetella pertussis B3585 ALH63825.1    
 B3621_1785   Bordetella pertussis B3621 ALI21975.1    
 B3629_1781   Bordetella pertussis B3629 ALI18544.1    
 B3640_1857   Bordetella pertussis B3640 ALH66611.1    
 B3658_1854   Bordetella pertussis B3658 ALH70073.1    
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