GlycosylTransferase Family 104

Activities in FamilydTDP-β-L-Rhap : arginine α-L-rhamnosyltransferase (EC 2.4.1.-)
Mechanism Inverting
NoteLassak et al. identified EarP as EF-P arginine R32 specific rhamnosyl transferase in Shewanella oneidensis using dTDP-b-L-rhamnose as donor substrate (PMID=25686373). The results of this study were subsequently confirmed for Pseudomonas aeruginosa (PMID=26060278), Pseudomonas putida (PMID=28951478) and Neisseria meningitidis (PMID=26840407). In 2016, it has been shown for S. oneidensis (PMID=28451135) and P. aeruginosa (PMID=28451332) that the enzyme is an inverting glycosyltransferase, thus mediating the formation of an a-L-rhamnosidic linkage. A structural basis for the arginine glycosylation reaction was provided by Krafczyk, Macosek and coworkers by having solved the crystal structure of the GT-B folding EarP from P. putida and an accompanying biochemical analysis of the enzyme (PMID=28951478).
Statistics GenBank accession (1295); Uniprot accession (0); PDB accession (5); 3D entries (2); cryst (0)
All (1296) Bacteria (1296) Structure (2) Characterized (4)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 13 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 BMULJ_01079   Burkholderia multivorans ATCC 17616 BAG43023.1
ABX15847.1
   
 NP80_1244   Burkholderia multivorans ATCC BAA-247 AJY18278.1    
 DM80_499   Burkholderia multivorans DDS 15A-1 AIO76293.1    
 A8H40_19725 (EarP)   Burkholderia multivorans FDAARGOS_246 AVR21647.1    
 BG90_2672   Burkholderia oklahomensis C6786 AJX31063.1
AOI45361.1
AOI45361.1
   
 DM82_2041   Burkholderia oklahomensis EO147 AIO66510.1    
 WG70_19070   Burkholderia oklahomensis EO147 AOI41773.1    
 bpln_1g09670   Burkholderia plantarii ATCC 43733 ALK29789.1    
 BP1026B_I0898   Burkholderia pseudomallei 1026b AFI65553.1
AJX07030.1
   
 DP48_1032   Burkholderia pseudomallei 1106a AIO88933.1    
 BURPS1106A_2831   Burkholderia pseudomallei 1106a ABN89073.1    
 DP48_1032   Burkholderia pseudomallei 1106a AIO88933.1    
 BURPS1710b_2885   Burkholderia pseudomallei 1710b ABA49110.1    
 ACT79_26815   Burkholderia pseudomallei 350105 ALB14043.1    
 BP3921G_24140   Burkholderia pseudomallei 3921 CDU29073.1    
 BG92_493   Burkholderia pseudomallei 406e AJW92447.1    
 DP50_1547   Burkholderia pseudomallei 576 AIO95341.1    
 BURPS668_2770   Burkholderia pseudomallei 668 ABN85199.1    
 BG97_741   Burkholderia pseudomallei 7894 AJX82716.1    
 DP46_2682   Burkholderia pseudomallei BEK AIO86650.1    
 AMS56_07440   Burkholderia pseudomallei 982 ALC56647.1    
 X996_1740   Burkholderia pseudomallei A79A AIV95609.1    
 X995_1788   Burkholderia pseudomallei B03 AIV90119.1    
 JE55_603   Burkholderia pseudomallei BDP AIP80684.1    
 DR61_2521   Burkholderia pseudomallei sp. BGK AIS48483.1    
 DP60_2349   Burkholderia pseudomallei BGR AIP13823.1    
 TR70_1360   Burkholderia pseudomallei Bp1651 ALJ70916.1    
 BPC006_I2869   Burkholderia pseudomallei BPC006 AFR16724.1    
 DU27_1567   Burkholderia pseudomallei BSR AIP70112.1    
 BFR05_05700   Burkholderia pseudomallei Burk178-Type1 APF91377.1    
 BFR05_05700   Burkholderia pseudomallei Burk178-Type1 APF91377.1    
 BFR06_05710   Burkholderia pseudomallei Burk178-Type2 APF97425.1    
 DR55_2095   Burkholderia pseudomallei HBPUB10134a AIP52388.1    
 DR54_2158   Burkholderia pseudomallei HBPUB10303a AIP58670.1    
 X993_2750   Burkholderia pseudomallei K42 AIV62682.1    
 BPSL2421   Burkholderia pseudomallei K96243 CAH36424.1
AJX29566.1
   
 A7U58_06535   Burkholderia pseudomallei M1 ANW49752.1    
 DP58_2583   Burkholderia pseudomallei Mahidol-1106a AIO13876.1    
 A7U59_06530   Burkholderia pseudomallei MS ANW57921.1    
 Y603_1690   Burkholderia pseudomallei MSHR1153 AIV50394.1    
 BBN_1013   Burkholderia pseudomallei MSHR146 AHG68541.1    
 DP51_3026   Burkholderia pseudomallei MSHR1655 AIP05123.1    
 Y044_2775   Burkholderia pseudomallei MSHR2243 AIV60645.1    
 BG16_1290   Burkholderia pseudomallei MSHR2543 AJX79329.1    
 BDL_3020   Burkholderia pseudomallei MSHR305 AGR73374.1    
 GBP346_A2951   Burkholderia pseudomallei MSHR346 ACQ98320.1    
 DP55_812   Burkholderia pseudomallei MSHR346 AIP11006.1    
 BGI46_12640   Burkholderia pseudomallei MSHR3763 APZ25613.1    
 X978_1298   Burkholderia pseudomallei MSHR3965 AIV84815.1    
 BGI47_12635   Burkholderia pseudomallei MSHR4083 APZ19421.1    
 BG17_3154   Burkholderia pseudomallei MSHR491 AJX23819.1    
 BBQ_886   Burkholderia pseudomallei MSHR511 AHG35337.1    
 BBX_1421   Burkholderia pseudomallei MSHR520 AHK66344.1    
 DP65_2775   Burkholderia pseudomallei MSHR5848 AIP39325.1    
 DP63_1667   Burkholderia pseudomallei MSHR5855 AIP23568.1    
 DR56_2169   Burkholderia pseudomallei MSHR5858 AIP47348.1    
 BGI52_12965   Burkholderia pseudomallei MSHR5864 APZ13390.1    
 Y028_3362   Burkholderia pseudomallei MSHR62 AIV71486.1    
 BH02_1083   Burkholderia pseudomallei MSHR668 AJX87868.1    
 BGI49_12865   Burkholderia pseudomallei MSHR6755 APY99803.1    
 BGI50_12605   Burkholderia pseudomallei MSHR7929 APY93679.1    
 BG19_2281   Burkholderia pseudomallei MSHR840 AJX72092.1    
 BBS_2495   Burkholderia pseudomallei NAU20B-16 AHE32498.1    
 BBU_3137   Burkholderia pseudomallei NAU35A-3 AIS86426.1    
 BBJ_408   Burkholderia pseudomallei NCTC 13178 AHE28090.1    
 BBK_2532   Burkholderia pseudomallei NCTC 13179 AGZ29845.1    
 DP47_3238   Burkholderia pseudomallei Pasteur 52237 AJX61220.1    
 BG24_2186   Burkholderia pseudomallei PB08298010 AJX95987.1    
 DP45_01594   Burkholderia pseudomallei BEJ AJX38120.1    
 X988_2369   Burkholderia pseudomallei TSV 48 AIV49048.1    
 X994_12   Burkholderia pseudomallei sp. TSV202 AIV78556.1    
 X994_12   Burkholderia pseudomallei sp. TSV202 AIV78556.1    
 BK015_05740   Burkholderia pseudomallei VB976100 APD34716.1    
 BK015_05740   Burkholderia pseudomallei VB976100 APD34716.1    
 UQ47_12600   Burkholderia pseudomallei vgh07 AJW53805.1    
 AM256_12770   Burkholderia pseudomallei vgh16R ALB94390.1    
 AM256_12770   Burkholderia pseudomallei vgh16R ALB94390.1    
 AM257_12795   Burkholderia pseudomallei vgh16W ALC00462.1    
 ABD05_11325   Burkholderia pyrrocinia DSM 10685 AKM00747.1    
 CUJ89_05845   Burkholderia pyrrocinia mHSR5 AXF20073.1    
 BW21_1356   Burkholderia sp. 2002721687 AJY41476.1    
 bAD24_I16580   Burkholderia sp. AD24 ASL45094.1    
 WS70_05575   Burkholderia sp. BDU6 AOJ01365.1    
 WS71_18495   Burkholderia sp. BDU8 AOJ09348.1    
 AQ610_06150   Burkholderia sp. Bp5365 MSMB43 ALX42051.1    
 BC1001_2527   Burkholderia sp. CCGE1001 ADX55943.1    
 BC1002_2121   Burkholderia sp. CCGE1002 ADG16180.1    
 BC1003_2498   Burkholderia sp. CCGE1003 ADN58451.1    
 AC233_12975   Burkholderia sp. HB1 ALE55481.1    
 DCN14_20090 (EarP)   Burkholderia sp. IDO3 AXK64955.1    
 DM992_15885 (EarP)   Burkholderia sp. JP2-270 AWV00824.1    
 A9R05_11000   Burkholderia sp. KK1 AQG99292.1    
 WS66_23120   Burkholderia sp. LA-2-3-30-S1-D2 AOI98515.1    
 WS78_05085   Burkholderia sp. MSMB0266 AOJ68200.1    
 WS86_06280   Burkholderia sp. MSMB0852 AOJ80270.1    
 WS87_11850   Burkholderia sp. MSMB0856 AOJ87320.1    
 WT60_06240   Burkholderia sp. MSMB617WGS AOK46495.1    
 AYM40_14595   Burkholderia sp. OLGA172 ANB73447.1    
 AXG89_00960   Burkholderia sp. PAMC 26561 AME25060.1    
 AX768_10695   Burkholderia sp. PAMC 28687 AMM14494.1    
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