GlycosylTransferase Family 104

Activities in FamilydTDP-β-L-Rhap : arginine α-L-rhamnosyltransferase (EC 2.4.1.-)
Mechanism Inverting
NoteLassak et al. identified EarP as EF-P arginine R32 specific rhamnosyl transferase in Shewanella oneidensis using dTDP-b-L-rhamnose as donor substrate (PMID=25686373). The results of this study were subsequently confirmed for Pseudomonas aeruginosa (PMID=26060278), Pseudomonas putida (PMID=28951478) and Neisseria meningitidis (PMID=26840407). In 2016, it has been shown for S. oneidensis (PMID=28451135) and P. aeruginosa (PMID=28451332) that the enzyme is an inverting glycosyltransferase, thus mediating the formation of an a-L-rhamnosidic linkage. A structural basis for the arginine glycosylation reaction was provided by Krafczyk, Macosek and coworkers by having solved the crystal structure of the GT-B folding EarP from P. putida and an accompanying biochemical analysis of the enzyme (PMID=28951478).
Statistics GenBank accession (1018); Uniprot accession (0); PDB accession (1); 3D entries (1); cryst (0)
All (1021) Bacteria (1021) Structure (1) Characterized (4)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 11 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AL474_04545   Bordetella pertussis ATCC:BAA-1335D-5 AMG21806.1    
 B1838_1990   Bordetella pertussis B1838 ALH49409.1    
 B1865_1784   Bordetella pertussis B1865 ALH52682.1    
 B1917_1785   Bordetella pertussis B1917 AIW92171.1    
 B1920_1865   Bordetella pertussis B1920 AIW95725.1    
 BBB38_10270   Bordetella pertussis B202 ANT93366.1    
 ADU61_07860   Bordetella pertussis B203 ANT89313.1    
 B3405_1858   Bordetella pertussis B3405 ALH56228.1    
 B3582_1785   Bordetella pertussis B3582 ALH59607.1    
 B3585_2608   Bordetella pertussis B3585 ALH63825.1    
 B3621_1785   Bordetella pertussis B3621 ALI21975.1    
 B3629_1781   Bordetella pertussis B3629 ALI18544.1    
 B3640_1857   Bordetella pertussis B3640 ALH66611.1    
 B3658_1854   Bordetella pertussis B3658 ALH70073.1    
 B3913_1856   Bordetella pertussis B3913 ALH73532.1    
 B3921_1857   Bordetella pertussis B3921 ALH76994.1    
 RD15_10325   Bordetella pertussis C393 AMS69581.1    
 BPTD_1981   Bordetella pertussis CS AEE67297.1    
 RD16_10040   Bordetella pertussis E476 AMS73165.1    
 UN82_10080   Bordetella pertussis H321 ALX21536.1    
 RD03_09320   Bordetella pertussis H374 AMS76746.1    
 RD04_08800   Bordetella pertussis H375 AMS94779.1    
 RD05_09115   Bordetella pertussis H378 AMS80332.1    
 RD06_10065   Bordetella pertussis H379 AMS84120.1    
 RD07_08990   Bordetella pertussis H380 AMS87555.1    
 RD08_09005   Bordetella pertussis H489 AMS51349.1    
 RD09_09115   Bordetella pertussis H542 AMS54988.1    
 RD10_09110   Bordetella pertussis H559 AMS91200.1    
 RD11_10540   Bordetella pertussis H561 AMS58874.1    
 RD12_09370   Bordetella pertussis H563 AMS62197.1    
 RD19_08995   Bordetella pertussis H564 AMT02079.1    
 RD13_08885   Bordetella pertussis H622 AMS65759.1    
 RD14_08880   Bordetella pertussis H627 AMS98388.1    
 OZ70_10075   Bordetella pertussis H788 AMT05875.1    
 RD17_11120   Bordetella pertussis I344 ANA17300.1    
 RD20_09300   Bordetella pertussis I468 AMT09365.1    
 RD21_10085   Bordetella pertussis I469 AMT13078.1    
 RD22_10080   Bordetella pertussis I472 AMT16681.1    
 QR48_08890   Bordetella pertussis I476 AMT20108.1    
 QR49_08890   Bordetella pertussis I480 AMT23701.1    
 QR50_09980   Bordetella pertussis I483 AMT27485.1    
 QR51_08885   Bordetella pertussis I496 AMT30914.1    
 QR52_09130   Bordetella pertussis I498 AMT34533.1    
 QR54_09315   Bordetella pertussis I518 AMT38159.1    
 QR55_09975   Bordetella pertussis I521 AMT41885.1    
 QR56_09305   Bordetella pertussis I538 AMT45368.1    
 QR57_09310   Bordetella pertussis I539 AMT48973.1    
 QR58_08765   Bordetella pertussis I646 AMT52479.1    
 QR59_10375   Bordetella pertussis I656 AMT56375.1    
 QR60_09005   Bordetella pertussis I669 AMT59709.1    
 QR61_06385   Bordetella pertussis I707 AMT62880.1    
 RD18_09315   Bordetella pertussis I979 ALX24989.1    
 BH370_10270   Bordetella pertussis J445 AOY20571.1    
 BH371_11595   Bordetella pertussis J446 AOY24431.1    
 BH372_10190   Bordetella pertussis J447 AOY27839.1    
 BH373_10815   Bordetella pertussis J448 AOY31700.1    
 BP2011   Bordetella pertussis Tohama I CAE42291.1    
 A8B87_10635   Bordetella pertussis VA-010 ANT33704.1    
 A8B86_11595   Bordetella pertussis VA-09 ANT15720.1    
 A8B92_11650   Bordetella pertussis VA-145 ANT30252.1    
 A8B88_02740   Bordetella pertussis VA-15 ANT17800.1    
 A8B93_09315   Bordetella pertussis VA-150 ANT04418.1    
 A8B94_09985   Bordetella pertussis VA-175 ANT00934.1    
 A8B89_07780   Bordetella pertussis VA-18 ANT22242.1    
 A8B96_11135   Bordetella pertussis VA-194 ANS97507.1    
 A8B97_04590   Bordetella pertussis VA-198 ANT10826.1    
 A8B91_09320   Bordetella pertussis VA-62 ANT26205.1    
 A7970_04270   Bordetella pertussis VA-UT25Sm1 ANT36248.1    
 Bpet3367   Bordetella petrii DSM 12804 CAP43709.1    
 BBN53_04815   Bordetella pseudohinzii HI4681 ANY15272.1    
 AKI39_07510   Bordetella sp. H567 AOB33507.1    
 ASB57_14305   Bordetella sp. N ALM83989.1    
 SAMEA3906487_00015   Bordetella trematum H044680328 SAI65977.1    
 Bamb_1018   Burkholderia ambifaria AMMD ABI86577.1    
 CH72_524   Burkholderia ambifaria AMMD AJY23270.1    
 BamMC406_1022   Burkholderia ambifaria MC40-6 ACB63513.1    
 A2T82_14920   Burkholderia cenocepacia 842 AMU07503.1    
 Bcen_0662   Burkholderia cenocepacia AU 1054 ABF75572.1    
 BHQ31_05990   Burkholderia cenocepacia CR318 AQT49614.1    
 DM39_980   Burkholderia cenocepacia DDS 22E-1 AIO31580.1    
 DM40_1804   Burkholderia cenocepacia DWS 37E-2 AIO41216.1    
 BCN122_II1908   Burkholderia cenocepacia GIMC4560:Bcn122 ARF88651.1
ARF84254.1
ARF86062.1
   
 I35_1010   Burkholderia cenocepacia H111 CDN59533.1    
 Bcen2424_1142   Burkholderia cenocepacia HI2424 ABK07894.1    
 TQ36_15030   Burkholderia cenocepacia ST32 ALV57472.1    
 A8E75_23705   Burkholderia cenocepacia VC12308 AQQ42007.1    
 A8F32_25580   Burkholderia cenocepacia VC1254 AQQ49158.1    
 A8E96_05670   Burkholderia cenocepacia VC12802 AQQ31970.1    
 A8D61_14390   Burkholderia cenocepacia VC2307 AQQ19601.1    
 A8E88_16200   Burkholderia cenocepacia VC7848 AQQ27083.1    
 DM42_684   Burkholderia cepacia DDS 7H-2 AIO49016.1    
 CO711_14250   Burkholderia cepacia FDAARGOS_388 ATF78468.1    
 GEM_2377   Burkholderia cepacia GG4 AFQ48786.1    
 P350_13790   Burkholderia cepacia JBK9 ALX12534.1    
 XM57_15320   Burkholderia cepacia LO6 AKE04179.1    
 BCCH1_40330   Burkholderia contaminans CH-1 BBA41571.1    
 WI95_05310   Burkholderia contaminans FL-1-2-30-S1-D0 AOL03390.1    
 NL30_09945   Burkholderia contaminans MS14 AKM40204.1    
 AK34_2029   Burkholderia dolosa AU0158 AJY13154.1    
 BM43_2442   Burkholderia gladioli ATCC 10248 AJW98175.1    
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