GlycosylTransferase Family 104

Activities in FamilydTDP-β-L-Rhap : arginine α-L-rhamnosyltransferase (EC 2.4.1.-)
Mechanism Inverting
NoteLassak et al. identified EarP as EF-P arginine R32 specific rhamnosyl transferase in Shewanella oneidensis using dTDP-b-L-rhamnose as donor substrate (PMID=25686373). The results of this study were subsequently confirmed for Pseudomonas aeruginosa (PMID=26060278), Pseudomonas putida (PMID=28951478) and Neisseria meningitidis (PMID=26840407). In 2016, it has been shown for S. oneidensis (PMID=28451135) and P. aeruginosa (PMID=28451332) that the enzyme is an inverting glycosyltransferase, thus mediating the formation of an a-L-rhamnosidic linkage. A structural basis for the arginine glycosylation reaction was provided by Krafczyk, Macosek and coworkers by having solved the crystal structure of the GT-B folding EarP from P. putida and an accompanying biochemical analysis of the enzyme (PMID=28951478).
Statistics GenBank accession (2176); Uniprot accession (0); PDB accession (9); 3D entries (3); cryst (0)
All (2172) Bacteria (2172) Structure (3) Characterized (4)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 22 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 BFW41_05415   Aeromonas hydrophila ZYAH75 AXV33378.1    
 GWI30_05390 (EarP)   Aeromonas media MC64 QHQ50445.1    
 E4185_12000 (EarP)   Aeromonas media R1-18 QJT26795.1    
 E4187_15865 (EarP)   Aeromonas media R25-3 QJT35649.1    
 E4188_02005 (EarP)   Aeromonas media R50-22 QJT37474.1    
 E4184_05905 (EarP)   Aeromonas media T0.1-19 QJT21023.1    
 E4186_05570 (EarP)   Aeromonas media T5-8 QJT29736.1    
 WP7W18E02_10670   Aeromonas media WP7-W18-ESBL-02 BBS86170.1    
 B224_0950   Aeromonas media WS AHX59952.1    
 C7N77_19505 (EarP)   Aeromonas rivipollensis KN-Mc-11N1 AVP95142.1    
 CHQ57_16175   Aeromonas salmonicida A527 ATU98799.1    
 CE456_18820   Aeromonas salmonicida S121 ASI24364.1    
 CE463_18815   Aeromonas salmonicida S44 ASI28683.1    
 CE462_17765   Aeromonas salmonicida S68 ASI32813.1    
 BHG40_21070   Aeromonas salmonicida subsp. masoucida RFAS1 ATD40134.1    
 Asalp_35960   Aeromonas salmonicida subsp. pectinolytica 34mel ATP10688.1    
 C5P03_05480 (EarP)   Aeromonas salmonicida subsp. salmonicida 01-B526 AYO62330.1    
 ASA_1087 (fragment)   Aeromonas salmonicida subsp. salmonicida A449 ABO89209.1    
 AXA69_002470 (EarP)   Aeromonas salmonicida subsp. salmonicida J223 QHU94703.1    
 GO992_18950 (EarP)   Aeromonas salmonicida subsp. salmonicida J409 QHE45083.1    
 GO994_05720 (EarP)   Aeromonas salmonicida subsp. salmonicida J410 QHE46886.1    
 GO993_01210 (EarP)   Aeromonas salmonicida subsp. salmonicida J411 QJF54675.1    
 E3D14_16670 (EarP)   Aeromonas salmonicida subsp. salmonicida SHY16-3432 QEO84886.1    
 E2P79_18190 (EarP)   Aeromonas schubertii LF1708 QCG49504.1    
 WL1483_3566   Aeromonas schubertii WL1483 ALP42985.1    
 FE240_01495 (EarP)   Aeromonas simiae A6 QFI53496.1    
 E5E96_01655 (EarP)   Aeromonas sp. 1805 QJT16118.1    
 E5E97_22075 (EarP)   Aeromonas sp. 2692-1 QJT15331.1    
 C2U37_13105   Aeromonas sp. ASNIH1 AUZ80490.1    
 C3F36_16500   Aeromonas sp. ASNIH2 AUY10924.1    
 C2U39_05645   Aeromonas sp. ASNIH3 AUV11710.1    
 C2U40_04265   Aeromonas sp. ASNIH4 AUZ74097.1    
 C2U30_08085   Aeromonas sp. ASNIH5 AUT41676.1    
 C2U47_15670   Aeromonas sp. ASNIH7 AUV17820.1    
 CK910_10895   Aeromonas sp. CA23 ATL98929.1    
 CK911_12260   Aeromonas sp. CU5 ATL93508.1    
 O23A_p0258   Aeromonas sp. O23A ARW81010.1    
 C7U63_20990 (EarP)   Aeromonas veronii 17ISAe AXV22182.1    
 GIS01_16735 (EarP)   Aeromonas veronii A8-AHP QHB83675.1    
 WM43_17745   Aeromonas veronii AVNIH1 ANB54366.1    
 GRF56_18535 (EarP)   Aeromonas veronii AVNIH1 QHC09245.1    
 B565_0929   Aeromonas veronii B565 AEB48964.1    
 A6033_08690   Aeromonas veronii CB51 ANB68669.1    
 C0073_005215 (EarP)   Aeromonas veronii FC951 AYK17360.1    
 FOB40_09450 (EarP)   Aeromonas veronii FDAARGOS_632 QET79473.1    
 FGM04_18795 (EarP)   Aeromonas veronii HX3 QGW98394.1    
 HXV88_16840 (EarP)   Aeromonas veronii JC529 QLH68002.1    
 EFI48_05320 (EarP)   Aeromonas veronii MS-18-37 AYV36281.1    
 AMS64_06385   Aeromonas veronii TH0426 AMQ42031.1    
 WP2S18C03_34200   Aeromonas veronii WP2-S18-CRE-03 BBQ54339.1    
 WP3W19E03_33160   Aeromonas veronii WP3-W19-ESBL-03 BBR40791.1    
 WP8S18E11_33300   Aeromonas veronii WP8-S18-ESBL-11 BBT81664.1    
 WP8W19C03_09620   Aeromonas veronii WP8-W19-CRE-03 BBT94268.1    
 WP9W18E04_10180   Aeromonas veronii WP9-W18-ESBL-04 BBU03679.1    
 CVS41_05235   Aeromonas veronii X11 ATY76585.1    
 CVS42_04580   Aeromonas veronii X12 ATY80179.1    
 EO082_05260 (EarP)   Aeromonas veronii ZfB1 QIF43488.1    
 FMZ60_05980 (EarP)   Alcaligenaceae bacterium SJ-26 QDQ87176.1    
 CA948_10045   Alcaligenes aquatilis BU33N AWG36946.1    
 D3M96_06380 (EarP)   Alcaligenes aquatilis QD168 AYN22694.1    
 EYC51_13105 (EarP)   Alcaligenes faecalis AN70 QBH21448.1    
 D0C27_15510 (EarP)   Alcaligenes faecalis AU14 QCP84077.1    
 CDA61_05255   Alcaligenes faecalis BDB4 ASC91871.1    
 CPY64_03795   Alcaligenes faecalis DSM 30030 ATI01703.1    
 EGY22_09560 (EarP)   Alcaligenes faecalis FDAARGOS_491 AYZ93506.1    
 D6I95_16455 (EarP)   Alcaligenes faecalis J481 AYR22274.1    
 AFA_04775   Alcaligenes faecalis JQ135 ASR91379.1    
 DUD43_05140 (EarP)   Alcaligenes faecalis Mc250 QFY79729.1    
 GWQ43_05985 (EarP)   Alcaligenes faecalis MUB14 QHS35652.1    
 ALFP_1020   Alcaligenes faecalis P156 ARP52907.1    
 Alide_2792   Alicycliphilus denitrificans BC ADV00523.1    
 HF896_13620 (EarP)   Alicycliphilus denitrificans DP3 QKD44598.1    
 Alide2_1677   Alicycliphilus denitrificans K601 AEB84067.1    
 DEH84_06740 (EarP)   Aquabacterium olei NBRC 110486 AWI53161.1    
 BXU06_14985   Aquaspirillum sp. LM1 AQR66203.1    
 DLM_2794   Aquitalea magnusonii H3 BBF86395.1    
 DKK66_13075 (EarP)   Aquitalea sp. USM4 QBJ78932.1    
 CEW87_05820   Azoarcus communis TSNA42 AWI78919.1    
 CEW83_14490   Azoarcus communis TSPY31 AWI76274.1    
 dqs_0095   Azoarcus olearius DQS4 ANQ83178.1    
 azo0085   Azoarcus sp. BH72 CAL92703.1    
 CJ010_00450   Azoarcus sp. DD4 QDF95127.1    
 CDA09_00180   Azoarcus sp. DN11 AYH41816.1    
 AZKH_0036   Azoarcus sp. KH32C BAL22388.1    
 G3580_19615 (EarP)   Azoarcus sp. M9-3-2 QID19630.1    
 C0099_00110   Azoarcus sp. SY39 AUN93474.1    
 Dsui_2468   Azospira oryzae PS AEV26826.1    
 AZSP09_07210   Azospira sp. I09 BBN87698.1    
 ACG10_06205   Azotobacter chroococcum B3 ASL25950.1    
 Achr_27570   Azotobacter chroococcum NCIMB 8003 AJE22180.1    
 AvCA_15270   Azotobacter vinelandii CA AGK15295.1    
 AvCA6_15270   Azotobacter vinelandii CA6 AGK19950.1    
 Avin_15270   Azotobacter vinelandii DJ ATCC BAA-1303 ACO77742.1    
 D521_1412   beta proteobacterium CB AGG33981.1    
 BWI17_11830   Betaproteobacteria bacterium GR16-43 APV50319.1    
 B0B51_19955   blood disease bacterium A2-HR MARDI AQW32153.1    
 BDB_mp60173   blood disease bacterium R229 CCA83008.1    
 BAV2517   Bordetella avium 197N CAJ50127.1    
 C0J07_12535   Bordetella avium JBBA AZY53221.1    
 C0J09_12600   Bordetella avium Owl19 AZY49882.1    
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