GlycosylTransferase Family 104

Activities in FamilydTDP-β-L-Rhap : arginine α-L-rhamnosyltransferase (EC 2.4.1.-)
Mechanism Inverting
NoteLassak et al. identified EarP as EF-P arginine R32 specific rhamnosyl transferase in Shewanella oneidensis using dTDP-b-L-rhamnose as donor substrate (PMID=25686373). The results of this study were subsequently confirmed for Pseudomonas aeruginosa (PMID=26060278), Pseudomonas putida (PMID=28951478) and Neisseria meningitidis (PMID=26840407). In 2016, it has been shown for S. oneidensis (PMID=28451135) and P. aeruginosa (PMID=28451332) that the enzyme is an inverting glycosyltransferase, thus mediating the formation of an a-L-rhamnosidic linkage. A structural basis for the arginine glycosylation reaction was provided by Krafczyk, Macosek and coworkers by having solved the crystal structure of the GT-B folding EarP from P. putida and an accompanying biochemical analysis of the enzyme (PMID=28951478).
Statistics GenBank accession (2176); Uniprot accession (0); PDB accession (9); 3D entries (3); cryst (0)
All (2172) Bacteria (2172) Structure (3) Characterized (4)
| 1 | ... | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ... | 22 |
Protein Name EC#OrganismGenBank UniprotPDB/3D
 bgla_1g10600   Burkholderia gladioli BSR3 AEA59743.1    
 EDD84_10180 (EarP)   Burkholderia gladioli Co14 AYQ87715.1    
 A8H28_35860   Burkholderia gladioli pv. gladioli FDAARGOS_188 AWY56271.1    
 CO712_08380   Burkholderia gladioli pv. gladioli FDAARGOS_389 ATF85057.1    
 CEJ98_05295   Burkholderia gladioli pv. gladioli KACC 11889 ASD78487.1    
 EXE55_15205 (EarP)   Burkholderia glumae 257sh-1 QHP92177.1    
 CG017_01916   Burkholderia glumae 336gr-1 QKM53892.1    
 B7760_00471   Burkholderia glumae 411gr-6 QKM46475.1    
 GQR88_04255 (EarP)   Burkholderia glumae AU6208 QHE09672.1    
 bglu_1g09720   Burkholderia glumae BGR1 ACR28152.1    
 GAS19_12810 (EarP)   Burkholderia glumae GX QGA38406.1    
 GAS18_05205 (EarP)   Burkholderia glumae HN QJW78201.1    
 HJC54_28770 (EarP)   Burkholderia glumae HN1 QJP73979.1    
 KS03_1905   Burkholderia glumae LMG 2196 = ATCC 33617 AJY67242.1    
 BGL_1c10090   Burkholderia glumae PG1 AJK45536.1    
 BRPE64_ACDS19570   Burkholderia insecticola RPE64 BAN23711.1    
 CVS37_06410   Burkholderia lata A05 AYQ37780.1    
 Bcep18194_A4254   Burkholderia lata sp. 383 ABB07851.1    
 BG99_3145   Burkholderia mallei 11 AJX42464.1    
 DM57_2570   Burkholderia mallei 2000031063 AIO82528.1    
 BO07_2275   Burkholderia mallei 2002721276 AJY35600.1    
 BM45_979   Burkholderia mallei 2002734299 AJX03355.1    
 BO06_2115   Burkholderia mallei 2002734306 AJX52942.1    
 DM55_1939   Burkholderia mallei 23344 AIO50900.1    
 DM78_1147   Burkholderia mallei 6 AIO58980.1    
 BMA0551   Burkholderia mallei ATCC 23344 AAU49352.1    
 BHL98_23215   Burkholderia mallei Bahrain1 AOP67741.1    
 DM76_1914   Burkholderia mallei BMQ AIO62395.1    
 RY28_02645   Burkholderia mallei FMH ATE31689.1    
 DM51_340   Burkholderia mallei FMH 23344 AIP77768.1    
 BM47_2809   Burkholderia mallei India86-567-2 AJX49174.1    
 RY29_02620   Burkholderia mallei JHU ATE36657.1    
 BM94_1893   Burkholderia mallei KC_1092 AJX65172.1    
 BMA10229_A2823   Burkholderia mallei NCTC 10229 ABN03553.1    
 BMA10247_1781   Burkholderia mallei NCTC 10247 ABO07307.1    
 BM44_1418   Burkholderia mallei NCTC 10247 AIS29574.1    
 BMASAVP1_A2458   Burkholderia mallei SAVP1 ABM51358.1    
 NM78_13775   Burkholderia mallei Turkey1 ATD89933.1    
 NW99_14470   Burkholderia mallei Turkey10 ATE43638.1    
 NW91_13755   Burkholderia mallei Turkey2 ATD94687.1    
 NW92_14175   Burkholderia mallei Turkey3 ATD99503.1    
 NW93_14385   Burkholderia mallei Turkey4 ATE04408.1    
 NW94_13840   Burkholderia mallei Turkey5 ATE09237.1    
 NW95_13765   Burkholderia mallei Turkey6 ATE14101.1    
 NW96_14095   Burkholderia mallei Turkey7 ATE19051.1    
 NW97_14275   Burkholderia mallei Turkey8 ATE23968.1    
 NW98_11720   Burkholderia mallei Turkey9 ATE28364.1    
 BMULJ_01079   Burkholderia multivorans ATCC 17616 BAG43023.1
 NP80_1244   Burkholderia multivorans ATCC BAA-247 AJY18278.1    
 DM80_499   Burkholderia multivorans DDS 15A-1 AIO76293.1    
 A8H40_19725 (EarP)   Burkholderia multivorans FDAARGOS_246 AVR21647.1    
 EGY31_32635 (EarP)   Burkholderia multivorans FDAARGOS_496 AYZ67771.1    
 EGY20_17195 (EarP)   Burkholderia multivorans FDAARGOS_547 AYY58489.1    
 EGY19_04350 (EarP)   Burkholderia multivorans FDAARGOS_548 AYY96758.1    
 FOB30_20195 (EarP)   Burkholderia multivorans FDAARGOS_622 QET40011.1    
 FOB31_06185 (EarP)   Burkholderia multivorans FDAARGOS_623 QET29419.1    
 FOB32_15820 (EarP)   Burkholderia multivorans FDAARGOS_624 QIX17088.1    
 FOC27_08680 (EarP)   Burkholderia multivorans FDAARGOS_719 QGR60290.1    
 FOC30_18420 (EarP)   Burkholderia multivorans FDAARGOS_722 QGR92911.1    
 FOC34_15750 (EarP)   Burkholderia multivorans FDAARGOS_726 QGR86702.1    
 BG90_2672   Burkholderia oklahomensis C6786 AJX31063.1
 DM82_2041   Burkholderia oklahomensis EO147 AIO66510.1    
 WG70_19070   Burkholderia oklahomensis EO147 AOI41773.1    
 bpln_1g09670   Burkholderia plantarii ATCC 43733 ALK29789.1    
 BP1026B_I0898   Burkholderia pseudomallei 1026b AFI65553.1
 DP48_1032   Burkholderia pseudomallei 1106a AIO88933.1    
 BURPS1106A_2831   Burkholderia pseudomallei 1106a ABN89073.1    
 BURPS1710b_2885   Burkholderia pseudomallei 1710b ABA49110.1    
 ACT79_26815   Burkholderia pseudomallei 350105 ALB14043.1    
 BP3921G_24140   Burkholderia pseudomallei 3921 CDU29073.1    
 BG92_493   Burkholderia pseudomallei 406e AJW92447.1    
 DP50_1547   Burkholderia pseudomallei 576 AIO95341.1    
 BURPS668_2770   Burkholderia pseudomallei 668 ABN85199.1    
 BG97_741   Burkholderia pseudomallei 7894 AJX82716.1    
 DP46_2682   Burkholderia pseudomallei BEK AIO86650.1    
 AMS56_07440   Burkholderia pseudomallei 982 ALC56647.1    
 X996_1740   Burkholderia pseudomallei A79A AIV95609.1    
 X995_1788   Burkholderia pseudomallei B03 AIV90119.1    
 JE55_603   Burkholderia pseudomallei BDP AIP80684.1    
 DR61_2521   Burkholderia pseudomallei BGK AIS48483.1    
 DP60_2349   Burkholderia pseudomallei BGR AIP13823.1    
 TR70_1360   Burkholderia pseudomallei Bp1651 ALJ70916.1    
 BPC006_I2869   Burkholderia pseudomallei BPC006 AFR16724.1    
 DU27_1567   Burkholderia pseudomallei BSR AIP70112.1    
 BFR05_05700   Burkholderia pseudomallei Burk178-Type1 APF91377.1    
 BFR05_05700   Burkholderia pseudomallei Burk178-Type1 APF91377.1    
 BFR06_05710   Burkholderia pseudomallei Burk178-Type2 APF97425.1    
 DR55_2095   Burkholderia pseudomallei HBPUB10134a AIP52388.1    
 DR54_2158   Burkholderia pseudomallei HBPUB10303a AIP58670.1    
 X993_2750   Burkholderia pseudomallei K42 AIV62682.1    
 BPSL2421   Burkholderia pseudomallei K96243 CAH36424.1
 A7U58_06535   Burkholderia pseudomallei M1 ANW49752.1    
 DP58_2583   Burkholderia pseudomallei Mahidol-1106a AIO13876.1    
 A7U59_06530   Burkholderia pseudomallei MS ANW57921.1    
 Y603_1690   Burkholderia pseudomallei MSHR1153 AIV50394.1    
 BBN_1013   Burkholderia pseudomallei MSHR146 AHG68541.1    
 DP51_3026   Burkholderia pseudomallei MSHR1655 AIP05123.1    
 Y044_2775   Burkholderia pseudomallei MSHR2243 AIV60645.1    
 BG16_1290   Burkholderia pseudomallei MSHR2543 AJX79329.1    
 BDL_3020   Burkholderia pseudomallei MSHR305 AGR73374.1    

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