GlycosylTransferase Family 104

Activities in FamilydTDP-β-L-Rhap : arginine α-L-rhamnosyltransferase (EC 2.4.1.-)
Mechanism Inverting
NoteLassak et al. identified EarP as EF-P arginine R32 specific rhamnosyl transferase in Shewanella oneidensis using dTDP-b-L-rhamnose as donor substrate (PMID=25686373). The results of this study were subsequently confirmed for Pseudomonas aeruginosa (PMID=26060278), Pseudomonas putida (PMID=28951478) and Neisseria meningitidis (PMID=26840407). In 2016, it has been shown for S. oneidensis (PMID=28451135) and P. aeruginosa (PMID=28451332) that the enzyme is an inverting glycosyltransferase, thus mediating the formation of an a-L-rhamnosidic linkage. A structural basis for the arginine glycosylation reaction was provided by Krafczyk, Macosek and coworkers by having solved the crystal structure of the GT-B folding EarP from P. putida and an accompanying biochemical analysis of the enzyme (PMID=28951478).
Statistics GenBank accession (2404); Uniprot accession (0); PDB accession (9); 3D entries (3); cryst (0)
All (2396) Bacteria (2396) Structure (3) Characterized (4)
| 1 | ... | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ... | 24 |
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ASB57_14305   Bordetella sp. N ALM83989.1    
 EYB34_00075 (EarP)   Bordetella trematum CBM01 QIM69906.1    
 BBB39_14705   Bordetella trematum F581 AZR94882.1    
 SAMEA3906487_00015   Bordetella trematum H044680328 SAI65977.1    
 Bamb_1018   Burkholderia ambifaria AMMD ABI86577.1    
 CH72_524   Burkholderia ambifaria AMMD AJY23270.1    
 JG536_05315 (EarP)   Burkholderia ambifaria BJQ0010 QQJ98081.1    
 BamMC406_1022   Burkholderia ambifaria MC40-6 ACB63513.1    
 J4G50_12365 (EarP)   Burkholderia anthina 1CH1 QTD88618.1    
 JFN94_05535 (EarP)   Burkholderia anthina BJQ0011 QQK03629.1    
 A2T82_14920   Burkholderia cenocepacia 842 AMU07503.1    
 Bcen_0662   Burkholderia cenocepacia AU 1054 ABF75572.1    
 BHQ31_05990   Burkholderia cenocepacia CR318 AQT49614.1    
 DM39_980   Burkholderia cenocepacia DDS 22E-1 AIO31580.1    
 DM40_1804   Burkholderia cenocepacia DWS 37E-2 AIO41216.1    
 FOC28_13865 (EarP)   Burkholderia cenocepacia FDAARGOS_720 QIY40836.1    
 FOC42_27475 (EarP)   Burkholderia cenocepacia FDAARGOS_734 QKT95475.1    
 BCN122_II1908   Burkholderia cenocepacia GIMC4560:Bcn122 ARF88651.1
 I35_1010   Burkholderia cenocepacia H111 CDN59533.1    
 Bcen2424_1142   Burkholderia cenocepacia HI2424 ABK07894.1    
 K562_12755   Burkholderia cenocepacia K56-2 QNN05098.1    
 B9Z07_18385   Burkholderia cenocepacia PC184 Mulks AWG30847.1    
 SY91_01579   Burkholderia cenocepacia PS27 QND94185.1    
 TQ36_15030   Burkholderia cenocepacia ST32 ALV57472.1    
 A8E75_23705   Burkholderia cenocepacia VC12308 AQQ42007.1    
 A8F32_25580   Burkholderia cenocepacia VC1254 AQQ49158.1    
 A8E96_05670   Burkholderia cenocepacia VC12802 AQQ31970.1    
 A8D61_14390   Burkholderia cenocepacia VC2307 AQQ19601.1    
 A8E88_16200   Burkholderia cenocepacia VC7848 AQQ27083.1    
 D5R55_05780 (EarP)   Burkholderia cenocepacia YG-3 AZQ50552.1    
 C7S14_4163   Burkholderia cepacia 39628 QOH32918.1    
 EJ998_05905 (EarP)   Burkholderia cepacia ATCC 25416 QCY02697.1    
 BURCE16_05530   Burkholderia cepacia BC16 QFS36197.1    
 DM42_684   Burkholderia cepacia DDS 7H-2 AIO49016.1    
 CO711_14250   Burkholderia cepacia FDAARGOS_388 ATF78468.1    
 GEM_2377   Burkholderia cepacia GG4 AFQ48786.1    
 P350_13790   Burkholderia cepacia JBK9 ALX12534.1    
 XM57_15320   Burkholderia cepacia LO6 AKE04179.1    
 BCCH1_40330   Burkholderia contaminans CH-1 BBA41571.1    
 WI95_05310   Burkholderia contaminans FL-1-2-30-S1-D0 AOL03390.1    
 NL30_09945   Burkholderia contaminans MS14 AKM40204.1    
 SK875_A00021   Burkholderia contaminans SK875 QFR08259.1    
 GON15_26765 (EarP)   Burkholderia contaminans XL73 QGW72680.1    
 FPQ37_05875 (EarP)   Burkholderia contaminans ZCC QDS25795.1    
 AK34_2029   Burkholderia dolosa AU0158 AJY13154.1    
 I6K02_11685 (EarP)   Burkholderia dolosa FDAARGOS_1272 QRO76576.1    
 EGY28_29555 (EarP)   Burkholderia dolosa FDAARGOS_562 AYZ98950.1    
 BM43_2442   Burkholderia gladioli ATCC 10248 AJW98175.1    
 bgla_1g10600   Burkholderia gladioli BSR3 AEA59743.1    
 EDD84_10180 (EarP)   Burkholderia gladioli Co14 AYQ87715.1    
 A8H28_35860   Burkholderia gladioli pv. gladioli FDAARGOS_188 AWY56271.1    
 CO712_08380   Burkholderia gladioli pv. gladioli FDAARGOS_389 ATF85057.1    
 CEJ98_05295   Burkholderia gladioli pv. gladioli KACC 11889 ASD78487.1    
 EXE55_15205 (EarP)   Burkholderia glumae 257sh-1 QHP92177.1    
 CG017_01916   Burkholderia glumae 336gr-1 QKM53892.1    
 B7760_00471   Burkholderia glumae 411gr-6 QKM46475.1    
 GQR88_04255 (EarP)   Burkholderia glumae AU6208 QHE09672.1    
 bglu_1g09720   Burkholderia glumae BGR1 ACR28152.1    
 I6G78_16465 (EarP)   Burkholderia glumae FDAARGOS_921 QQM90703.1    
 GAS19_12810 (EarP)   Burkholderia glumae GX QGA38406.1    
 GAS18_05205 (EarP)   Burkholderia glumae HN QJW78201.1    
 HJC54_28770 (EarP)   Burkholderia glumae HN1 QJP73979.1    
 KS03_1905   Burkholderia glumae LMG 2196 = ATCC 33617 AJY67242.1    
 BGL_1c10090   Burkholderia glumae PG1 AJK45536.1    
 I6G56_14335 (EarP)   Burkholderia humptydooensis FDAARGOS_899 QPS42762.1    
 CVS37_06410   Burkholderia lata A05 AYQ37780.1    
 Bcep18194_A4254   Burkholderia lata sp. 383 ABB07851.1    
 BG99_3145   Burkholderia mallei 11 AJX42464.1    
 DM57_2570   Burkholderia mallei 2000031063 AIO82528.1    
 BO07_2275   Burkholderia mallei 2002721276 AJY35600.1    
 BM45_979   Burkholderia mallei 2002734299 AJX03355.1    
 BO06_2115   Burkholderia mallei 2002734306 AJX52942.1    
 DM55_1939   Burkholderia mallei 23344 AIO50900.1    
 DM78_1147   Burkholderia mallei 6 AIO58980.1    
 BMA0551   Burkholderia mallei ATCC 23344 AAU49352.1    
 BHL98_23215   Burkholderia mallei Bahrain1 AOP67741.1    
 DM76_1914   Burkholderia mallei BMQ AIO62395.1    
 RY28_02645   Burkholderia mallei FMH ATE31689.1    
 DM51_340   Burkholderia mallei FMH 23344 AIP77768.1    
 BM47_2809   Burkholderia mallei India86-567-2 AJX49174.1    
 RY29_02620   Burkholderia mallei JHU ATE36657.1    
 BM94_1893   Burkholderia mallei KC_1092 AJX65172.1    
 BMA10229_A2823   Burkholderia mallei NCTC 10229 ABN03553.1    
 BMA10247_1781   Burkholderia mallei NCTC 10247 ABO07307.1    
 BM44_1418   Burkholderia mallei NCTC 10247 AIS29574.1    
 BMASAVP1_A2458   Burkholderia mallei SAVP1 ABM51358.1    
 NM78_13775   Burkholderia mallei Turkey1 ATD89933.1    
 NW99_14470   Burkholderia mallei Turkey10 ATE43638.1    
 NW91_13755   Burkholderia mallei Turkey2 ATD94687.1    
 NW92_14175   Burkholderia mallei Turkey3 ATD99503.1    
 NW93_14385   Burkholderia mallei Turkey4 ATE04408.1    
 NW94_13840   Burkholderia mallei Turkey5 ATE09237.1    
 NW95_13765   Burkholderia mallei Turkey6 ATE14101.1    
 NW96_14095   Burkholderia mallei Turkey7 ATE19051.1    
 NW97_14275   Burkholderia mallei Turkey8 ATE23968.1    
 NW98_11720   Burkholderia mallei Turkey9 ATE28364.1    
 BMULJ_01079   Burkholderia multivorans ATCC 17616 BAG43023.1
 NP80_1244   Burkholderia multivorans ATCC BAA-247 AJY18278.1    
 DM80_499   Burkholderia multivorans DDS 15A-1 AIO76293.1    
 A8H40_19725 (EarP)   Burkholderia multivorans FDAARGOS_246 AVR21647.1    

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