GlycosylTransferase Family 104

Activities in FamilydTDP-β-L-Rhap : arginine α-L-rhamnosyltransferase (EC 2.4.1.-)
Mechanism Inverting
NoteLassak et al. identified EarP as EF-P arginine R32 specific rhamnosyl transferase in Shewanella oneidensis using dTDP-b-L-rhamnose as donor substrate (PMID=25686373). The results of this study were subsequently confirmed for Pseudomonas aeruginosa (PMID=26060278), Pseudomonas putida (PMID=28951478) and Neisseria meningitidis (PMID=26840407). In 2016, it has been shown for S. oneidensis (PMID=28451135) and P. aeruginosa (PMID=28451332) that the enzyme is an inverting glycosyltransferase, thus mediating the formation of an a-L-rhamnosidic linkage. A structural basis for the arginine glycosylation reaction was provided by Krafczyk, Macosek and coworkers by having solved the crystal structure of the GT-B folding EarP from P. putida and an accompanying biochemical analysis of the enzyme (PMID=28951478).
Statistics GenBank accession (2176); Uniprot accession (0); PDB accession (9); 3D entries (3); cryst (0)
All (2172) Bacteria (2172) Structure (3) Characterized (4)
| 1 | ... | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | ... | 22 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CHL79_21215   Delftia acidovorans RAY209 ATH14767.1    
 Daci_2872   Delftia acidovorans SPH-1 ABX35510.1    
 DelCs14_3860   Delftia sp. Cs1-4 AEF90848.1    
 BO996_13265   Delftia sp. HK171 APE48745.1    
 BI380_09090   Delftia tsuruhatensis CM13 AOV05859.1    
 GCS91_19510 (EarP)   Delftia tsuruhatensis TR1180 QFS66344.1    
 B9N43_03330   Denitratisoma sp. DHT3 QDX80378.1    
 BA022_01890   Diaphorobacter polyhydroxybutyrativorans SL-205 ASI67438.1    
 G7047_04515 (EarP)   Diaphorobacter sp. HDW4A QIL79249.1    
 G7048_20030 (EarP)   Diaphorobacter sp. HDW4B QIL72445.1    
 HND92_12875 (EarP)   Diaphorobacter sp. JS3050 QJY33772.1    
 HH213_00640 (EarP)   Duganella sp. AF9R3 QJD88750.1    
 HH212_16690 (EarP)   Duganella sp. GN2-R2 QJE01469.1    
 ELB75_00610 (fragment)   Eikenella corrodens KCOM 3110 AZR60732.1    
 SAMEA4412678_01032   Eikenella corrodens NCTC10596 SNW08453.1    
 EZJ17_09025 (fragment)   Eikenella exigua PXX QED92974.1    
 DTO96_101936   Ephemeroptericola cinctiostellae F02 AXF86190.1    
 OYT1_ch2036   Ferriphaselus amnicola OYT1 BBE51562.1    
 HO274_12430 (EarP)   Ferrovum myxofaciens QKE42016.1    
 HO273_12305 (EarP)   Ferrovum myxofaciens QKE39400.1    
 RN87_06485   Fusobacterium hwasookii ChDC F174 ALQ40178.1    
 RN92_07115   Fusobacterium hwasookii ChDC F206 ALQ35674.1    
 RN97_05600   Fusobacterium hwasookii ChDC F300 ALQ37693.1    
 C4N19_07505   Fusobacterium mortiferum ATCC 9817 AVQ18948.1    
 EGX98_08955   Fusobacterium necrophorum FDAARGOS_565 AYZ74144.1    
 C4N15_04490   Fusobacterium necrophorum subsp. funduliforme 1_1_36S AVQ20942.1    
 BWX37_02840   Fusobacterium necrophorum subsp. funduliforme F1260 AYV94615.1    
 BSQ88_02660   Fusobacterium necrophorum subsp. funduliforme F1291 AYV92641.1    
 EO219_10605   Fusobacterium necrophorum subsp. necrophorum ATCC 25286 AZW09975.1    
 HOO60_07995 (EarP)   Fusobacterium nucleatum Fn12230 QJX50828.1    
 HMPREF0409_00860   Fusobacterium nucleatum subsp. animalis 4_8 AGM23324.1    
 FSDG_00303   Fusobacterium nucleatum subsp. animalis 7_1 EEO41744.1    
 CBG60_07525   Fusobacterium nucleatum subsp. animalis ChDC F332 ASG31071.1    
 RN98_07355   Fusobacterium nucleatum subsp. animalis KCOM 1279 ALF17996.1    
 RO08_03275   Fusobacterium nucleatum subsp. animalis KCOM 1325 ALF21343.1    
 C7Y58_06640 (EarP)   Fusobacterium nucleatum subsp. nucleatum 25586 AVQ15118.1    
 C4N14_08630 (EarP)   Fusobacterium nucleatum subsp. nucleatum ATCC 23726 AVQ23608.1    
 FN0719   Fusobacterium nucleatum subsp. nucleatum ATCC 25586 AAL94915.1    
 RO05_07035   Fusobacterium nucleatum subsp. nucleatum ChDC F316 KCOM 1322 ALF24132.1    
 RN84_06835   Fusobacterium nucleatum subsp. nucleatum ChDC F317 ASG26569.1    
 RN95_01605   Fusobacterium nucleatum subsp. nucleatum KCOM 1250 ALF25187.1    
 RO02_02465   Fusobacterium nucleatum subsp. polymorphum ChDC F306 ALM93517.1    
 RN93_06580   Fusobacterium nucleatum subsp. polymorphum ChDC F319 ALQ42467.1    
 CBG50_05980   Fusobacterium nucleatum subsp. polymorphum KCOM 1260 (=ChDC F218) ASC02897.1    
 CBG61_03570   Fusobacterium nucleatum subsp. polymorphum KCOM 1275 ASG28104.1    
 ERS445057_01527   Fusobacterium nucleatum subsp. polymorphum NCTC10562 CKH00579.1    
 HMPREF0405_01054   Fusobacterium nucleatum subsp. vincentii 3_1_27 EFG34775.1    
 HMPREF0946_00201   Fusobacterium nucleatum subsp. vincentii 3_1_36A2 EEU32128.1    
 RN99_05270   Fusobacterium nucleatum subsp. vincentii ChDC F8 KCOM 1231 ALF19899.1    
 CS401_00945   Fusobacterium nucleatum subsp. vincentii KCOM 2931 ATV05475.1    
 C4N17_02415   Fusobacterium periodonticum 2_1_31 AVQ24645.1    
 CTM72_11395   Fusobacterium periodonticum KCOM 1261 ATV60255.1    
 CTM64_05695   Fusobacterium periodonticum KCOM 1262 ATV35583.1    
 CTM74_06665   Fusobacterium periodonticum KCOM 1263 ATV61523.1    
 CTM78_03340   Fusobacterium periodonticum KCOM 1277 ATV63508.1    
 CTM86_05635   Fusobacterium periodonticum KCOM 1282 ATV66115.1    
 CTM68_09285   Fusobacterium periodonticum KCOM 1283 ATV57849.1    
 CTM92_02110   Fusobacterium periodonticum KCOM 2305 ATV67522.1    
 CTM98_06525   Fusobacterium periodonticum KCOM 2555 ATV70327.1    
 CTN00_02480   Fusobacterium periodonticum KCOM 2653 ATV71944.1    
 AXF16_08685   Fusobacterium sp. oral taxon 203 W7671 ASS40151.1    
 C4N20_16125   Fusobacterium ulcerans ATCC 49185 AVQ29678.1    
 NCTC12112_01818   Fusobacterium ulcerans NCTC12112 SQJ04048.1    
 C4N18_14830   Fusobacterium varium ATCC 27725 AVQ32594.1    
 FV113G1_21700   Fusobacterium varium Fv113-g1 BBA51820.1    
 NCTC10560_00990   Fusobacterium varium NCTC10560 VEH38595.1    
 Galf_0622   Gallionella capsiferriformans ES-2 ADL54664.1    
 DKL61_03470 (fragment)   Gammaproteobacteria bacterium ESL0073 AWM79483.1    
 DKL61_03475 (fragment)   Gammaproteobacteria bacterium ESL0073 AWM79484.1    
 A9404_12485   Halothiobacillus sp. LS2 ANJ68083.1    
 F506_14895   Herbaspirillum hiltneri N3 AKZ63781.1    
 E2K99_15745 (EarP)   Herbaspirillum huttiense NFYY 53159 QBP76374.1    
 RC54_16240   Herbaspirillum rubrisubalbicans DSM 11543 AYR25277.1    
 Hrubri_3079   Herbaspirillum rubrisubalbicans M1 ALU90248.1    
 C798_17280   Herbaspirillum rubrisubalbicans Os34 QJQ01925.1    
 EJD96_15005 (EarP)   Herbaspirillum seropedicae AU13965 QDD65378.1    
 Hsc_3017   Herbaspirillum seropedicae AU14040 AON55293.1    
 Hsero_3062   Herbaspirillum seropedicae SmR1 ADJ64550.1    
 ACP92_15365   Herbaspirillum seropedicae Z67 AKN66478.1    
 hmeg3_15085   Herbaspirillum sp. meg3 ASU39482.1    
 HEAR0987   Herminiimonas arsenicoxydans CAL61169.1    
 LPB072_14130   Hydrogenophaga crassostreae LPB0072 AOW13809.1    
 HPF_09650   Hydrogenophaga pseudoflava DSM 1084 QBM27951.1    
 G9Q37_09710 (EarP)   Hydrogenophaga sp. BA0156 QIM52398.1    
 F9K07_12380 (EarP)   Hydrogenophaga sp. BPS33 QHE85642.1    
 E5678_07505 (EarP)   Hydrogenophaga sp. PAMC20947 QCB45875.1    
 Q5W_08510   Hydrogenophaga sp. PBC AOS82130.1    
 F9Z44_08585 (EarP)   Hydrogenophaga sp. PBL-H3 QHE80539.1    
 F9Z45_08585 (EarP)   Hydrogenophaga sp. PBL-H3 QHE76115.1    
 BSY239_2183   Hydrogenophaga sp. RAC07 AOF87336.1    
 HPTL_0421   Hydrogenophilus thermoluteolus TH-1 BBD76689.1    
 DW355_13615 (EarP)   Hylemonella gracilis NS1 QBK06598.1    
 Ilyop_2608   Ilyobacter polytropus DSM 2926 ADO84365.1    
 C1H71_11580   Iodobacter fluviatilis PCH194 QBC44105.1    
 EJO50_16425 (EarP)   Iodobacter sp. H11R3 AZN37913.1    
 D9M09_08075 (EarP)   Janthinobacterium agaricidamnosum BHSEK AYM75764.1    
 GJA_1540   Janthinobacterium agaricidamnosum NBRC 102515 = DSM 9628 CDG82185.1    
 G3257_10890 (EarP)   Janthinobacterium lividum EIF1 QKY02701.1    
 G8765_11140 (EarP)   Janthinobacterium lividum EIF2 QKY08252.1    
 EKL02_11920 (EarP)   Janthinobacterium sp. 17J80-10 QAU34834.1    
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