GlycosylTransferase Family 104

Activities in FamilydTDP-β-L-Rhap : arginine α-L-rhamnosyltransferase (EC 2.4.1.-)
Mechanism Inverting
NoteLassak et al. identified EarP as EF-P arginine R32 specific rhamnosyl transferase in Shewanella oneidensis using dTDP-b-L-rhamnose as donor substrate (PMID=25686373). The results of this study were subsequently confirmed for Pseudomonas aeruginosa (PMID=26060278), Pseudomonas putida (PMID=28951478) and Neisseria meningitidis (PMID=26840407). In 2016, it has been shown for S. oneidensis (PMID=28451135) and P. aeruginosa (PMID=28451332) that the enzyme is an inverting glycosyltransferase, thus mediating the formation of an a-L-rhamnosidic linkage. A structural basis for the arginine glycosylation reaction was provided by Krafczyk, Macosek and coworkers by having solved the crystal structure of the GT-B folding EarP from P. putida and an accompanying biochemical analysis of the enzyme (PMID=28951478).
Statistics GenBank accession (2404); Uniprot accession (0); PDB accession (9); 3D entries (3); cryst (0)
All (2396) Bacteria (2396) Structure (3) Characterized (4)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 24 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 GWQ43_05985 (EarP)   Alcaligenes faecalis MUB14 QHS35652.1    
 ALFP_1020   Alcaligenes faecalis P156 ARP52907.1    
 JYG33_00045 (EarP)   Alcaligenes sp. SORT26 QTB99922.1    
 DBV39_09190 (EarP)   Algicoccus marinus HZ20 AWB33853.1    
 Alide_2792   Alicycliphilus denitrificans BC ADV00523.1    
 HF896_13620 (EarP)   Alicycliphilus denitrificans DP3 QKD44598.1    
 ALDI51_29490   Alicycliphilus denitrificans I51 BCN39630.1    
 Alide2_1677   Alicycliphilus denitrificans K601 AEB84067.1    
 H3L97_11205 (EarP)   Alysiella filiformis DSM 16848 QMT31248.1    
 DEH84_06740 (EarP)   Aquabacterium olei NBRC 110486 AWI53161.1    
 BXU06_14985   Aquaspirillum sp. LM1 AQR66203.1    
 DLM_2794   Aquitalea magnusonii H3 BBF86395.1    
 DKK66_13075 (EarP)   Aquitalea sp. USM4 QBJ78932.1    
 CEW87_05820   Azoarcus communis TSNA42 AWI78919.1    
 CEW83_14490   Azoarcus communis TSPY31 AWI76274.1    
 dqs_0095   Azoarcus olearius DQS4 ANQ83178.1    
 C0099_00110   Azoarcus pumilus SY39 AUN93474.1    
 azo0085   Azoarcus sp. BH72 CAL92703.1    
 CJ010_00450   Azoarcus sp. DD4 QDF95127.1    
 CDA09_00180   Azoarcus sp. DN11 AYH41816.1    
 AZKH_0036   Azoarcus sp. KH32C BAL22388.1    
 G3580_19615 (EarP)   Azoarcus sp. M9-3-2 QID19630.1    
 Dsui_2468   Azospira oryzae PS AEV26826.1    
 IWH25_13585 (EarP)   Azospira restricta DSM 18626 QRJ62792.1    
 AZSP09_07210   Azospira sp. I09 BBN87698.1    
 ACG10_06205   Azotobacter chroococcum B3 ASL25950.1    
 GKQ51_06465 (EarP)   Azotobacter chroococcum HR1 QQE89961.1    
 Achr_27570   Azotobacter chroococcum NCIMB 8003 AJE22180.1    
 AvCA_15270   Azotobacter vinelandii CA AGK15295.1    
 AvCA6_15270   Azotobacter vinelandii CA6 AGK19950.1    
 Avin_15270   Azotobacter vinelandii DJ ATCC BAA-1303 ACO77742.1    
 D521_1412   beta proteobacterium CB AGG33981.1    
 BWI17_11830   Betaproteobacteria bacterium GR16-43 APV50319.1    
 B0B51_19955   blood disease bacterium A2-HR MARDI AQW32153.1    
 BDB_mp60173   blood disease bacterium R229 CCA83008.1    
 BAV2517   Bordetella avium 197N CAJ50127.1    
 C0J07_12535   Bordetella avium JBBA AZY53221.1    
 C0J09_12600   Bordetella avium Owl19 AZY49882.1    
 BAU08_07900   Bordetella bronchialis AU17976 ANN71266.1    
 BAU06_07670   Bordetella bronchialis AU3182 ANN66184.1    
 BN112_1674   Bordetella bronchiseptica 253 CCJ53591.1    
 BTL45_08920   Bordetella bronchiseptica A310 AUL14997.1    
 CS343_09210   Bordetella bronchiseptica A345 AZW30391.1    
 AL472_10680   Bordetella bronchiseptica ATCC:BAA-588D-5 AMG88199.1    
 CS344_08870   Bordetella bronchiseptica D448 AZW12115.1    
 B7P00_08965   Bordetella bronchiseptica D755 AWP84210.1    
 B9G72_08955   Bordetella bronchiseptica D973 AWQ09777.1    
 CS345_08875   Bordetella bronchiseptica D987 AZW21375.1    
 B7P04_08925   Bordetella bronchiseptica E001 AWP79396.1    
 B7P10_09185   Bordetella bronchiseptica E010 AWP74619.1    
 B2C13_08860   Bordetella bronchiseptica E016 QBS68701.1    
 B9G73_08835   Bordetella bronchiseptica F709 AWQ04828.1    
 FOB42_20990 (EarP)   Bordetella bronchiseptica FDAARGOS_634 QET72662.1    
 FOC01_21195 (EarP)   Bordetella bronchiseptica FDAARGOS_693 QIY02510.1    
 CWR61_08715   Bordetella bronchiseptica I124 AZW43599.1    
 BBB44_08625   Bordetella bronchiseptica I328 AOB26300.1    
 B7P02_08865   Bordetella bronchiseptica I943 AWP58096.1    
 CJ015_15410   Bordetella bronchiseptica KM22 AXT89853.1    
 BN115_1743   Bordetella bronchiseptica MO149 CCJ58499.1    
 NCTC10543_03036   Bordetella bronchiseptica NCTC10543 VEF43514.1    
 NCTC8344_01038   Bordetella bronchiseptica NCTC8344 VEI25313.1    
 BB1841   Bordetella bronchiseptica RB50 CAE32338.1    
 BBS798_1742   Bordetella bronchiseptica S798 BAO68468.1    
 CAL15_11235   Bordetella genomosp. 13 AU7206 ARP94900.1    
 CAL11_15215   Bordetella genomosp. 6 AU22978 ARP77405.1    
 CAL12_08150   Bordetella genomosp. 8 AU19157 ARP84422.1    
 CAL14_14630   Bordetella genomosp. 9 AU14267 ARP91370.1    
 CAL13_15105   Bordetella genomosp. 9 AU17164 ARP87389.1    
 CBR71_14275   Bordetella hinzii 14-3425 QDJ46893.1    
 CBR72_13700   Bordetella hinzii 243-2 QDJ55804.1    
 CBR67_14645   Bordetella hinzii 4134 QDJ37806.1    
 CBR70_14010   Bordetella hinzii 4449 QDJ42325.1    
 ACR54_03551   Bordetella hinzii F582 AKQ56841.1    
 FOB29_08745 (EarP)   Bordetella hinzii FDAARGOS_621 QET43700.1    
 G3T20_17935 (EarP)   Bordetella hinzii FY01 QII86396.1    
 ACR55_03464   Bordetella hinzii H568 AKQ61308.1    
 CS347_13505   Bordetella hinzii H720 AZW17710.1    
 NCTC13199_02090   Bordetella hinzii NCTC13199 VEH25183.1    
 SAMEA4040645_01066   Bordetella hinzii NCTC13200 SNV69074.1    
 CBR68_13235   Bordetella hinzii SV2 QDJ33208.1    
 CBR69_13640   Bordetella hinzii TR-1212 QDJ51283.1    
 D558_0800   Bordetella holmesii 44057 AIT25480.1    
 B7O96_15465   Bordetella holmesii C690 AWP94210.1    
 J3Q26_02495 (EarP)   Bordetella holmesii CIDM-BH3 QSY67796.1    
 FYA37_15770 (EarP)   Bordetella holmesii D130 QGF12567.1    
 B7O97_15445   Bordetella holmesii F028 AWP68121.1    
 FYA38_15740 (EarP)   Bordetella holmesii F029 QGF09308.1    
 FYA39_15750 (EarP)   Bordetella holmesii F061 QGF06061.1    
 B2B12_15600   Bordetella holmesii F274 QBS66417.1    
 FYA40_15750 (EarP)   Bordetella holmesii F586 QGF01733.1    
 FYA42_15740 (EarP)   Bordetella holmesii F588 QGE98487.1    
 FYA43_15740 (EarP)   Bordetella holmesii F589 QGE95243.1    
 FYA44_15740 (EarP)   Bordetella holmesii F590 QGE91989.1    
 FYA45_15735 (EarP)   Bordetella holmesii F592 QGE88737.1    
 FYA46_15735 (EarP)   Bordetella holmesii F593 QGE85495.1    
 FYA47_15780 (EarP)   Bordetella holmesii F594 QGE82241.1    
 FYA48_15740 (EarP)   Bordetella holmesii F595 QGE78994.1    
 F783_014480   Bordetella holmesii F627 AMD49863.1    
 FYA55_15740 (EarP)   Bordetella holmesii H108 QGE54933.1    
 FYA57_15730 (EarP)   Bordetella holmesii H248 QGE47518.1    
Top


Last update: 2021-03-26 © Copyright 1998-2021
AFMB - CNRS - Université d'Aix-Marseille