GlycosylTransferase Family 104

Activities in FamilydTDP-β-L-Rhap : arginine α-L-rhamnosyltransferase (EC 2.4.1.-)
Mechanism Inverting
NoteLassak et al. identified EarP as EF-P arginine R32 specific rhamnosyl transferase in Shewanella oneidensis using dTDP-b-L-rhamnose as donor substrate (PMID=25686373). The results of this study were subsequently confirmed for Pseudomonas aeruginosa (PMID=26060278), Pseudomonas putida (PMID=28951478) and Neisseria meningitidis (PMID=26840407). In 2016, it has been shown for S. oneidensis (PMID=28451135) and P. aeruginosa (PMID=28451332) that the enzyme is an inverting glycosyltransferase, thus mediating the formation of an a-L-rhamnosidic linkage. A structural basis for the arginine glycosylation reaction was provided by Krafczyk, Macosek and coworkers by having solved the crystal structure of the GT-B folding EarP from P. putida and an accompanying biochemical analysis of the enzyme (PMID=28951478).
Statistics GenBank accession (1174); Uniprot accession (0); PDB accession (5); 3D entries (2); cryst (0)
All (1176) Bacteria (1176) Structure (2) Characterized (4)
| 1 | ... | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | ... | 12 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 SAMN06296273_1123   Nitrosomonas ureae Nm15 SNX59685.1    
 CEQ07_04390 (EarP)   Oligella urethralis FDAARGOS_329 AVL70727.1    
 ODI_R2902   Orrella dioscoreae SOE50698.1    
 C6570_14165 (EarP)   Ottowia sp. KADR8-3 AVO35248.1    
 ADJ79_09350   Ottowia sp. oral taxon 894 W10237 AKU67370.1    
 BRW83_1049   Oxalobacter formigenes HC-1 ARQ45797.1    
 BRW84_04900   Oxalobacter formigenes OXCC13 ARQ78027.1    
 PAEH1_12265   Paenalcaligenes hominis 15S00501 AQS52113.1    
 AA956_21440   Pandoraea apista AU2161 AKI63800.1    
 AT395_20840   Pandoraea apista DSM 16535 ALS68240.1    
 AL486_22905   Pandoraea apista FDAARGOS_126 AVF42205.1    
 XM39_04120   Pandoraea apista TF80G25 AKH71527.1    
 SG18_04120   Pandoraea apista TF81F4 AJE97551.1    
 AB870_07020   Pandoraea faecigallinarum DSM 23572 AKM32614.1    
 AT302_03605   Pandoraea norimbergensis DSM 11628 ALS58992.1    
 MB84_00055   Pandoraea oxalativorans DSM 23570 AKC71988.2    
 U875_03550   Pandoraea pnomenusa 3kgm AHB04582.2    
 LV28_09780   Pandoraea pnomenusa DSM 16536 AIU26793.1    
 A6P55_07110   Pandoraea pnomenusa MCB032 ANC44020.1    
 X636_05940   Pandoraea pnomenusa RB-44 AHB75032.1    
 DA70_20600   Pandoraea pnomenusa RB38 AHN76597.1    
 RO07_04100   Pandoraea pulmonicola DSM 16583 AJC23045.2    
 NA29_24960   Pandoraea sputorum DSM 21091 AJC18388.1    
 SAMEA4530655_04181   Pandoraea sputorum NCTC13161 SNU88303.1    
 PATSB16_31100   Pandoraea thiooxydans ATSB16 APR96448.1    
 ABW99_12655   Pandoraea thiooxydans DSM 25325 AKJ68929.1    
 UC34_20150   Pandoraea vervacti NS15 AJP59975.2    
 CJU94_10490   Paraburkholderia aromaticivorans ASW00353.1    
 ATN79_04885   Paraburkholderia caribensis Bcrs1W AMV42018.1    
 C2L66_04735   Paraburkholderia caribensis DSM 13236 AUT51238.1    
 K788_0005565   Paraburkholderia caribensis MBA4 ALL65921.1    
 AN416_13580   Paraburkholderia caribensis MWAP64 ALP63510.1    
 OI25_2531   Paraburkholderia fungorum ATCC BAA-463 AJZ58081.1    
 C2L64_04705   Paraburkholderia hospita DSM 17164 AUT67716.1    
 BUPH_03102 (fragment)   Paraburkholderia phenoliruptrix BR3459a AFT86676.1    
 Bphy_0850   Paraburkholderia phymatum STM815 ACC70039.1    
 Bphyt_2890   Paraburkholderia phytofirmans PsJN ACD17284.1    
 RBRH_02437   Paraburkholderia rhizoxinica HKI 454 CBW74328.1    
 BTO02_15155   Paraburkholderia sp. SOS3 APR37718.1    
 BJG93_01725   Paraburkholderia sprentiae WSM5005 APA84261.1    
 C2L65_04515   Paraburkholderia terrae DSM 17804 AUT58944.1    
 DR64_3257   Paraburkholderia xenovorans LB400 AIP31817.1    
 Bxe_A1094   Paraburkholderia xenovorans LB400 ABE31852.1    
 AT984_06585   Paucibacter sp. KCTC 42545 ALT79680.1    
 C7R88_01440 (EarP)   Plesiomonas shigelloides MS-17-188 AVQ86094.1    
 SAMEA2665130_01755   Plesiomonas shigelloides NCTC10360 SBT61264.1    
 Pnap_1626   Polaromonas naphthalenivorans CJ2 ABM36940.1    
 Bpro_3073   Polaromonas sp. JS666 ABE44987.1    
 AAW51_2046   [Polyangium] brachysporum DSM 7029 AKJ28737.1    
 AOC25_02595   Polynucleobacter asymbioticus MWH-RechtKol4 APC00588.1    
 A4F89_02590   Polynucleobacter asymbioticus MWH-RechtKolB APB98303.1    
 Pnuc_0414   Polynucleobacter asymbioticus QLW-P1DMWA-1 ABP33634.1    
 AOC10_02260   Polynucleobacter asymbioticus Tro8F10W22 APC05435.1    
 CL55_00015090   Polynucleobacter duraquae MWH-MoK4 AKD25842.1    
 Pnec_0422   Polynucleobacter necessarius STIR1 ACB43698.1    
 A8O14_02095   Polynucleobacter wuianus QLW-P1FAT50C-4 ANI98990.1    
 PTUN_b0402   Pseudoalteromonas tunicata D2 ATC96794.1    
 PA14OR_2194   Pseudomonas aeruginosa SCM62097.1    
 BMR72_10180   Pseudomonas aeruginosa APB64713.1    
 BMR72_10180   Pseudomonas aeruginosa APB64713.1    
 PERCYII10_2123   Pseudomonas aeruginosa SIP52384.1    
 AU380_17875   Pseudomonas aeruginosa 12-4-4(59) ALU49575.1    
 CD800_26170   Pseudomonas aeruginosa 1207 ASD12355.1    
 CDG41_11615   Pseudomonas aeruginosa 124 ASA28827.1    
 CD797_11935   Pseudomonas aeruginosa 127 ASD03217.1    
 CDL16_12260   Pseudomonas aeruginosa 58 ASA14938.1    
 PA8380_22890   Pseudomonas aeruginosa 8380 BAR67123.1    
 CD796_11690   Pseudomonas aeruginosa 84 ASC97109.1    
 AES1R_26415   Pseudomonas aeruginosa AES-1R ALT75129.1    
 CSC26_4727   Pseudomonas aeruginosa AR439 AWF02638.1    
 CSC28_2337   Pseudomonas aeruginosa AR441 AWE90286.1    
 CSC29_1452   Pseudomonas aeruginosa AR442 AWE81959.1    
 CSC31_2880   Pseudomonas aeruginosa AR444 AWE80294.1    
 CSC32_2497   Pseudomonas aeruginosa AR445 AWE71142.1    
 AM474_03440 (EarP)   Pseudomonas aeruginosa AR_0095 AVN42572.1    
 CSB85_0872   Pseudomonas aeruginosa AR_0230 AVK28707.1    
 CSB90_4701   Pseudomonas aeruginosa AR_0353 AVK22091.1    
 CSB91_0200   Pseudomonas aeruginosa AR_0354 AVK10727.1    
 CSB93_3554   Pseudomonas aeruginosa AR_0356 AVK06470.1    
 CSB94_6247   Pseudomonas aeruginosa AR_0357 AVJ98124.1    
 CSB97_1036   Pseudomonas aeruginosa AR_0360 AVJ94745.1    
 CSC27_1417   Pseudomonas aeruginosa AR_0440 AWF66084.1    
 CSC30_5749   Pseudomonas aeruginosa AR_0443 AWF56881.1    
 BGV84_10760   Pseudomonas aeruginosa ATCC 15692 AOP57602.1    
 A4W92_27310   Pseudomonas aeruginosa ATCC 27853 ANT75767.1
AMX90581.1
   
 G655_10545   Pseudomonas aeruginosa B136-33 AGI81032.1    
 A6R75_21255   Pseudomonas aeruginosa BAMC 07-48 ANA72553.1    
 YQ19_12925   Pseudomonas aeruginosa Carb01 63 AKE69083.1    
 B7D75_10875 (EarP)   Pseudomonas aeruginosa CR1 AVR67437.1    
 AOU28_09350   Pseudomonas aeruginosa Cu1510 ALS11775.1    
 AOU28_09350   Pseudomonas aeruginosa Cu1510 ALS11775.1    
 PADK1_02124   Pseudomonas aeruginosa DK1 CRZ29682.1    
 PADK2_10115   Pseudomonas aeruginosa DK2 AFM64310.1    
 BG483_09670   Pseudomonas aeruginosa DN1 AON71420.1    
 PA50071_10625   Pseudomonas aeruginosa DSM 50071 = NBRC 12689 AKO86238.1    
 E613_22220   Pseudomonas aeruginosa E6130952 ARG86320.1    
 F22031_24045   Pseudomonas aeruginosa F22031 AJD63497.1    
 HW10_02660   Pseudomonas aeruginosa F23197 ALY34037.1    
 HW09_33290   Pseudomonas aeruginosa F30658 ALY45664.1    
 HV91_11705 (EarP)   Pseudomonas aeruginosa F5677 AVE32805.1    
Top


Last update: 2018-06-11 © Copyright 1998-2018
AFMB - CNRS - Université d'Aix-Marseille