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Glycoside Hydrolase Family 5 / Subf 2

Activities in Sub FamilyChitosanase (EC 3.2.1.132);
Endo-β-1,4-glucanase (EC 3.2.1.4);
Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73);
Endo-β-1,4-xylanase (EC 3.2.1.8);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (10); Uniprot accession (147); PDB accession (47); 3D entries (17); cryst (0)
Summary
Download GH5_2 (2298) Taxonomic display Structure (17) Characterized (129)
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Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 HC658_19150 (EglS)   Bacillus subtilis subsp. subtilis UCMB5021 QJD04277.1     2
 HC659_19120 (EglS)   Bacillus subtilis subsp. subtilis UCMB5121 QJD00294.1     2
 endo-β-1,4-glucanase 3.2.1.4 Bacillus subtilis subsp. subtilis UMC7 AGG11030.1 M1R5G7   2
 BSSX_2016   Bacillus subtilis SX01705 ASK23911.1     2
 endo-β-1,4-glucanase (fragment)   Bacillus subtilis SYYS AFV95351.1     2
 A3772_09840   Bacillus subtilis SZMC 6179J AMS47376.1     2
 β-1,4-endo-glucanase, partial (fragment)   Bacillus subtilis T28d AHD24514.1     2
 BIS30_19935   Bacillus subtilis T30 AJW87252.1     2
 β-1,4-endo-glucanase, partial (fragment)   Bacillus subtilis t37a AHD24506.1     2
 ORF (fragment)   Bacillus subtilis T41a AIT71752.1     2
 cellulase   Bacillus subtilis TB-2 ABS70711.1     2
 CLD04_10445   Bacillus subtilis TLO3 ASZ61563.1     2
 M036_09535   Bacillus subtilis TO-A AII35811.1     2
 ABU16_2893   Bacillus subtilis TO-A JPC AKN13969.1     2
 ABA10_09875   Bacillus subtilis UD1022 AKI92270.1     2
 endo-1,4-β-glucanase   Bacillus subtilis VSDB5 QEA08555.1     2
 BKN48_19800   Bacillus subtilis VV2 AOY07432.1     2
 β-1,4-endo-glucanase, partial (fragment)   Bacillus subtilis w AHD24516.1     2
 D3Z87_09910   Bacillus subtilis WB800N AYE64410.1     2
 cellulase (Egls3)   Bacillus subtilis WL001 AOY41715.1     2
 endoglucanase (CelW)   Bacillus subtilis WL001 AHZ62779.1     2
 C663_1868 (EglS)   Bacillus subtilis XF-1 AGE63656.1     2
 xylanase (Xyl141)   Bacillus subtilis Xyl14-KBRB ADP09027.1     2
 β-1,4-endo-glucanase, partial (fragment)   Bacillus subtilis Y AHD24507.1     2
 GFX43_011830 (EglS)   Bacillus subtilis ZD01 QGU24489.1     2
 G4P54_10325   Bacillus tequilensis EA-CB0015 QIW80171.1     2
 endoglucanase (CeL)   Bacillus tequilensis S17I28 AIJ27554.1     2
 endo-β-1,4-glucanase (fragment)   Bacillus thuringiensis IARI-SP-6 AGW99983.1     2
 MKF32_09760   Bacillus vallismortis BL01 USP97304.1     2
 BV11031_07980   Bacillus vallismortis DSM 11031 QAV11188.1     2
 B9C48_09240   Bacillus vallismortis NBIF-001 ARM28000.1     2
 E4T61_09420   Bacillus velezensis QCC36190.1     2
 C0W57_06835   Bacillus velezensis 10075 AUS15916.1     2
 CFN60_09420   Bacillus velezensis 157 ASK58591.1     2
 EG882_14895   Bacillus velezensis 1B-23 AZJ44488.1     2
 EBA29_01894 (EglS)   Bacillus velezensis 83 QAR56922.1     2
 BK055_10270   Bacillus velezensis 9912D APA02899.1     2
 B7941_11800   Bacillus velezensis 9D-6 ARJ75167.1     2
 endoglucanase, partial (EglS)   Bacillus velezensis A4 AYO51733.1     2
 EYB46_01045   Bacillus velezensis ANSB01E QBK08640.1     2
 RZ52_09125   Bacillus velezensis AP183 AWK46308.1     2
 B938_09365   Bacillus velezensis AS43.3 AFZ90893.1     2
 D073_1756   Bacillus velezensis At1 QDF56117.1     2
 BMJ37_09290   Bacillus velezensis ATR2 ATU26929.1     2
 BAMMD1_1755 (EglS)   Bacillus velezensis B25 CUX93659.1     2
 HPQ66_09040   Bacillus velezensis B268 QKF33642.1     2
 GPY14_03160   Bacillus velezensis BA-26 QGZ43983.1     2
 EG219_08725   Bacillus velezensis BCSo1 AZG39173.1     2
 HB674_09180   Bacillus velezensis BIM B-1312D QIR72640.1     2
 D3C60_09205   Bacillus velezensis BIM B-439D AXY37919.1     2
 CMR26_07555   Bacillus velezensis BS-37 AWG38431.1     2
 BvL003_09135   Bacillus velezensis BvL03 QGJ64975.1     2
 GWK37_18565   Bacillus velezensis CACC 316 QHQ58997.1     2
 BACAU_1766 (BglC)   Bacillus velezensis CAU B946 CCF05300.1     2
 BCBMB205_18710   Bacillus velezensis CBMB205 ANF36769.1
ARN87289.1		     2
 A1D33_000185   Bacillus velezensis CC09 ANB45748.1     2
 C3Z10_09765   Bacillus velezensis CGMCC 11640 AVI28645.1     2
 CVD07_09175   Bacillus velezensis CN026 ATY28447.1     2
 A2I97_08780   Bacillus velezensis D2-2 AOU01160.1     2
 DA376_09390   Bacillus velezensis DR-08 AVV94124.1     2
 BVDSYZ_09785   Bacillus velezensis DSYZ AWX72297.1     2
 HNO13_09150   Bacillus velezensis EN01 QJW66824.1     2
 GRT15_09150   Bacillus velezensis FJAT-45028 QHC11861.1     2
 F3129_09710   Bacillus velezensis FJAT-46737 QEV91689.1     2
 F9286_09295   Bacillus velezensis FJAT-52631 QFS24835.1     2
 RBAM_018100   Bacillus velezensis FZB42 CAE11243.1
ABS74173.1		     2
 ABH13_1848   Bacillus velezensis G341 AKL76432.1     2
 GL331_14005   Bacillus velezensis GA1 QGT59575.1     2
 B6257_19060   Bacillus velezensis GFP-2 AUJ62547.1     2
 BAGQ_1973   Bacillus velezensis GQJK49 ARZ58207.1     2
 B9C53_00960   Bacillus velezensis GYL4 AWD12147.1     2
 GG619_09190   Bacillus velezensis HN-Q-8 QGU47594.1     2
 HCC49_08940   Bacillus velezensis Htq6 QIW83982.1     2
 B7L90_08260   Bacillus velezensis Hx05 AWM83213.1     2
 CJP14_07175   Bacillus velezensis J01 ASZ03660.1     2
 AAV29_08940   Bacillus velezensis JJ-D34 AKF30670.1     2
 NG74_01886 (EglS)   Bacillus velezensis JS25R AIU81966.1     2
 D5H27_06980   Bacillus velezensis JT3-1 QJD43999.1     2
 BAJT_09240   Bacillus velezensis JTYP2 ARB33457.1     2
 HUO02_09175   Bacillus velezensis KKLW QKT00296.1     2
 CRH11_14675   Bacillus velezensis L-1 ATO11163.1     2
 GJS30_10450   Bacillus velezensis LABIM22 QLG07474.1     2
 CQJ38_09320   Bacillus velezensis LABIM40 ATL39711.1     2
 EYS44_09250   Bacillus velezensis LB002 QBK79881.1     2
 F6467_09295   Bacillus velezensis LC1 QEX98065.1     2
 CMV18_11305   Bacillus velezensis LG37 QDL82288.1     2
 DDE72_07450   Bacillus velezensis LM23DO2 AWE16031.1     2
 SB21_09455   Bacillus velezensis LPL-K103 QCE18606.1     2
 A8142_08875   Bacillus velezensis LS69 ANU30279.1     2
 CXP43_10450   Bacillus velezensis Lzh-a42 AUG36120.1     2
 BBJ33_09410   Bacillus velezensis M75 AOO61741.1     2
 BVMH_09535   Bacillus velezensis MH25 AZI47122.1     2
 BAPNAU_1934 (BglC)   Bacillus velezensis NAU-B3 CDH95715.1     2
 AW02_018440 (BglC)   Bacillus velezensis NJN-6 AKD29994.1     2
 EEB07_19455   Bacillus velezensis NY12-2 AYV19409.1     2
 FZE25_09360   Bacillus velezensis ONU 553 QGH56744.1     2
 D0U03_09300   Bacillus velezensis OSY-GA1 AXT12600.1     2
 D1120_09125   Bacillus velezensis P34 QCT30002.1     2
 alkali tolerable endoglucanase, partial (Ega5)   Bacillus velezensis Q5 ALE32753.1     2
 BVQ_09580   Bacillus velezensis QST713 AWD87699.1     2
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