Glycoside Hydrolase Family 5 / Subf 2

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (1020); Uniprot accession (275); PDB accession (40); 3D entries (13); cryst (0)
All (905) Bacteria (737) Eukaryota (154) unclassified (14) Structure (13) Characterized (119)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 SAMN05428941_7586   Streptomyces sp. 2114.2 SDT81869.1     2
 ASR50_33260   Streptomyces sp. 4F ALV54720.1     2
 NI25_36320   Streptomyces sp. CCM_MD2014 AIV38329.1     2
 ABE83_05735   Streptomyces sp. CFMR 7 ALC26638.1     2
 CAC01_21465   Streptomyces sp. CLI2509 CLI2905 ASY34930.1     2
 AA958_30920   Streptomyces sp. CNQ-509 AKH85894.1     2
 F750_5063 (CelA)   Streptomyces sp. PAMC 26508 AGJ57501.1     2
 QR97_13405   Streptomyces sp. PBH53 AKN70681.1     2
 A6E92_04910   Streptomyces sp. S8 ARI51563.1     2
 CAG99_24650   Streptomyces sp. SCSIO 03032 ARQ71592.1     2
 SACTE_0482   Streptomyces sp. SirexAA-E AEN08423.1     2
 TK78_05020   Streptomyces sp. Tue 6075 Tue6075 APS18384.1     2
 ORF   Streptomyces sp. WAC1438 AFO53553.1     2
 cellulase (Cel5A)   Streptomyces thermocarboxydus C42 BAP18991.1     2
 SVEN_6970   Streptomyces venezuelae ATCC 10712 CCA60256.1     2
 BN2537_1935   Streptomyces venezuelae ATCC 15439 CUM36485.1     2
 AQF52_7272   Streptomyces venezuelae ATCC 15439 ALO12858.1     2
 B1H20_29330   Streptomyces violaceoruber S21 ARF65053.1     2
 SXIM_16110   Streptomyces xiamenensis 318 AKG42995.1     2
 TJEJU_1423   Tenacibaculum jejuense KCTC 22618 SNR15156.1     2
 bifunctional beta 1,4-endoglucanase/cellobiohydrolase, partial (CelaB) (fragment)   Teredinibacter turnerae PMS-1675L.S.0a.01 ARD05454.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-509L.S.1a.4 AHL25053.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-509L.S.1a.6 AHL25054.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-517Y.S.1a.10 AHL25051.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-535T.S.1b.3 AHL25050.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-539Y.S.1a.1 AHL25035.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-554M.S.1a.4 AHL25043.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-574K.S.1a.1 AHL25044.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-683H.S.1a.9 AHL25049.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-691W.S.1a.3 AHL25052.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T0609 AHL25040.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T0611 AHL25041.1     2
 TERTU_2895 (CelA)   Teredinibacter turnerae T7901 ACR12145.1 C5BNA9   2
 bifunctional β-1,4-endoglucanase / cellobiohydrolase (CelAB) 3.2.1.4
3.2.1.91
Teredinibacter turnerae T7901 ABS72374.1 A9Q634   2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T7902 AHL25042.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T7903 AHL25048.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T8401 AHL25055.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T8402 AHL25036.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T8412 AHL25046.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T8415 AHL25039.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T8503 AHL25045.1     2
 bifunctional b- 1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T8508 AHL25037.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T8509 AHL25038.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T8510 AHL25056.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T8513 AHL25047.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T8601 AHL25057.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T8602 AHL25034.1     2
 acid-, alkali- and thermo-tolerant GH5 endoglucanase, partial   Thermoactinospora rubra YIM 77501 AOP17814.1     2
 Tsac_0338   Thermoanaerobacterium saccharolyticum JW/SL-YS485 AFK85368.1     2
 Tsac_2253   Thermoanaerobacterium saccharolyticum JW/SL-YS485 AFK87257.1     2
 endo-β-1,4-glucanase / celulase (CelDZ1a) 3.2.1.4 Thermoanaerobacterium sp. A57Txylan ALX38276.1   5FIP[A,B,C,D] 2
 endo-β-1,4-glucanase 5A (E5;CelE;TfCel5A;Tfu_0901) (Cel5A) 3.2.1.4 Thermobifida fusca YX AAZ54939.1
AAC09379.1
Q01786
Q47RH8
2CKR[A,B]
2CKS[A,B]
2
 GH5 cellulase (Cel5A)   Thermobifida halotolerans YIM 90462 AFK65733.1     2
 Spica_2444   Treponema caldarium DSM 7334 AEJ20552.1     2
 Sequence 1 from patent US 6190899   uncultured actinomycete AAE60112.1     2
 endo-1,4-β-glucanase, partial (Cel5A) (fragment)   uncultured Bacillus sp. AKP92783.1     2
 ORF (fragment)   uncultured bacterium CAR66437.1 B5U8B2   2
 ORF (fragment)   uncultured bacterium CAR66438.1 B5U8B3   2
 glycoside hydrolase   uncultured bacterium AMO13171.1     2
 cellulase 5R (Cel5R;Cel5R_FS) 3.2.1.4 uncultured bacterium AND74761.1   5I2U[A,B] 2
 ORF (fragment)   uncultured bacterium ACN90881.1 C0M099   2
 ORF (fragment)   uncultured bacterium ACN90882.1 C0M0A0   2
 ORF (fragment)   uncultured bacterium ACN90883.1 C0M0A1   2
 ORF (fragment)   uncultured bacterium ACN90884.1 C0M0A2   2
 ORF (fragment)   uncultured bacterium ACN90885.1 C0M0A3   2
 ORF (fragment)   uncultured bacterium ACN90886.1 C0M0A4   2
 ORF (fragment)   uncultured bacterium ACN90888.1 C0M0A6   2
 ORF (fragment)   uncultured bacterium ACN90889.1 C0M0A7   2
 ORF (fragment)   uncultured bacterium ACN90890.1 C0M0A8   2
 ORF (fragment)   uncultured bacterium ACN90891.1 C0M0A9   2
 Endoglucanase A precursor   uncultured bacterium SIP56560.1     2
 Endoglucanase A precursor   uncultured bacterium SIP56505.1     2
 Endoglucanase A precursor   uncultured bacterium SIP56455.1     2
 Endoglucanase precursor   uncultured bacterium SIP56247.1     2
 bifunctional beta 1,4-endoglucanase/cellobiohydrolase, partial (CelaB) (fragment)   uncultured bacterium ARD05451.1     2
 bifunctional beta 1,4-endoglucanase/cellobiohydrolase, partial (CelaB) (fragment)   uncultured bacterium ARD05450.1     2
 bifunctional beta 1,4-endoglucanase/cellobiohydrolase, partial (CelaB) (fragment)   uncultured bacterium ARD05452.1     2
 cellulase (CelA3;BP-CelA3) (fragment)   uncultured bacterium AEW10554.1     2
 cellulase (CelA84;EF-84D8)   uncultured bacterium AEW10555.1     2
 YBcontig212-01191-9   uncultured bacterium ADU86904.1     2
 β-glucanase (UmCel5G;RC1) 3.2.1.4 uncultured bacterium ABA42184.1 Q3HXC4   2
 β-glucanase (UmCel5H;RC2) 3.2.1.4 uncultured bacterium ABA42185.1 Q3HXC3   2
 endo-β-1,4-glucanase (CRS200) (Cel5B) 3.2.1.4 uncultured bacterium AFJ44728.1     2
 endo-β-1,4-glucanase (CelWS15)   uncultured bacterium AFX88669.1     2
 endo-β-1,4-glucanase (CelWS3) 3.2.1.4 uncultured bacterium AFX88673.1     2
 endo-β-1,4-glucanase (CelWS14) 3.2.1.4 uncultured bacterium AFX88668.1     2
 endo-β-1,4-glucanase (CelWS6) 3.2.1.4 uncultured bacterium AFX88666.1     2
 endo-β-1,4-glucanase (CelWS36)   uncultured bacterium AFX88672.1     2
 endo-β-1,4-glucanase (CelWS7)   uncultured bacterium AFX88667.1     2
 endo-β-1,4-glucanase (CelWS20)   uncultured bacterium AFX88670.1     2
 endo-β-1,4-glucanase (CelWS30) (fragment) 3.2.1.4 uncultured bacterium AFX88671.1     2
 cellulase (CS10;CelCS10) 3.2.1.4 uncultured bacterium AGL50932.1     2
 endo-β-1,4-glucanase (RC3) 3.2.1.4 uncultured bacterium ABI94085.1 Q06B38   2
 endo-β-1,4-glucanase (RC5) 3.2.1.4 uncultured bacterium ABI94086.1 Q06B37   2
 endo-β-1,4-glucanase (Endos11)   uncultured bacterium AGW99967.1     2
 endo-β-1,4-glucanase (Endos9)   uncultured bacterium AGW99965.1     2
 endo-β-1,4-glucanase (Endos3)   uncultured bacterium AGW99959.1     2
 endo-β-1,4-glucanase (Endos15)   uncultured bacterium AGW99971.1     2
 endo-β-1,4-glucanase (Endos1)   uncultured bacterium AGW99957.1     2
 endo-β-1,4-glucanase (Endos19)   uncultured bacterium AGW99975.1     2
Top




Last update: 2017-10-09 © Copyright 1998-2017
AFMB - CNRS - Université d'Aix-Marseille