Glycoside Hydrolase Family 5 / Subf 2

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (1120); Uniprot accession (275); PDB accession (42); 3D entries (14); cryst (0)
All (1003) Bacteria (834) Eukaryota (155) unclassified (14) Structure (14) Characterized (120)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 LPB138_02890   Lutibacter sp. LPB0138 AOW19691.1     2
 Mahau_1113   Mahella australiensis 50-1 BON AEE96310.1     2
 BTR34_14425   Maribacter sp. T28 APQ18437.1     2
 CR152_18245   Massilia violaceinigra B2 ATQ78963.1     2
 MROS_0753   Melioribacter roseus P3M-2 AFN73995.1     2
 Mag101_04990   Microbulbifer agarilyticus GP101 AQQ67068.1     2
 Mag101_04970   Microbulbifer agarilyticus GP101 AQQ67064.1     2
 BTJ40_12585   Microbulbifer sp. A4B17 AWF81594.1     2
 A3224_06300   Microbulbifer thermotolerans DAU221 AMX02246.1     2
 Micau_2979   Micromonospora aurantiaca ATCC 27029 ADL46510.1 D9TBA5   2
 GA0070611_1781   Micromonospora auratinigra DSM 44815 SBT41892.1     2
 GA0070614_0094   Micromonospora coxensis DSM 45161 SCG34747.1     2
 GA0070610_3306   Micromonospora echinofusca DSM 43913 SCG17005.1     2
 GA0070618_5067   Micromonospora echinospora DSM 43816 SCF30627.1     2
 GA0070618_5917   Micromonospora echinospora DSM 43816 SCF37480.1     2
 GA0070621_1393   Micromonospora narathiwatensis DSM 45248 SBT42013.1     2
 GA0074696_3702   Micromonospora purpureochromogenes DSM 43821 SCF24260.1     2
 GA0070623_0785   Micromonospora rifamycinica DSM 44983 SCG41432.1     2
 GA0074704_3372   Micromonospora siamensis DSM 45097 SCG57304.1     2
 ML5_5408   Micromonospora sp. L5 ADU10877.1 D3C5S4   2
 CO540_05510   Micromonospora sp. WMMA2032 ATO13355.1     2
 GA0070619_3022   Micromonospora zamorensis DSM 45600 SCG53995.1     2
 A7982_04389   Minicystis rosea DSM 24000 APR79042.1     2
 SAMN05216490_0949   Mucilaginibacter mallensis MP1X4 SDS32391.1     2
 A0256_21225   Mucilaginibacter sp. PAMC 26640 AMR33776.1     2
 Niako_3530   Niastella koreensis GR20-10 AEV99831.1     2
 Niako_4179   Niastella koreensis GR20-10 AEW00453.1     2
 B005_3970   Nocardiopsis alba ATCC BAA-2165 AFR08794.1     2
 CGQ36_10255   Nocardiopsis dassonvillei HZNU_N_1 ASU57907.1     2
 A9R04_10425   Nocardiopsis dassonvillei NOCA502F APC35073.1     2
 Ndas_1368   Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 ADH66800.1 D7B2V2   2
 BN4615_P6407   Nonomuraea gerenzanensis ATCC 39727 SBO96891.1     2
 BKM31_10990   Nonomuraea sp. ATCC 55076 AQZ70298.1     2
 CW732_04295   Olleya sp. Bg11-27 AUC74935.1     2
 AR543_07145 (fragment)   Paenibacillus bovis BD3526 ANF95802.1     2
 cellulase (fragment)   Paenibacillus campinasensis BL11 ADI39639.1 D8WN01   2
 B9T62_05285   Paenibacillus donghaensis KCTC 13049 ASA20263.1     2
 B4V02_06945   Paenibacillus kribbensis AM49 ASR46431.1     2
 Sequence 9 from patent US 7364891 (Egl-N131b)   Paenibacillus KSM-N131 ACE14926.1     2
 endo-β-1,4-glucanase 3a (possible fragment)   Paenibacillus lautus CAA01935.1     2
 PM3016_5775   Paenibacillus mucilaginosus 3016 AFC32453.1     2
 B2K_29390   Paenibacillus mucilaginosus K02 AFH64766.1
AFK65318.1
    2
 KNP414_06148   Paenibacillus mucilaginosus KNP414 AEI44672.1     2
 ABE82_18615   Paenibacillus peoriae HS311 ALA43398.1     2
 VK72_19185   Paenibacillus polymyxa ATCC 15970 APQ60687.1     2
 LK13_05895   Paenibacillus polymyxa CF05 AIY08152.1     2
 LK13_24440   Paenibacillus polymyxa CF05 AIY11516.1     2
 X809_19720   Paenibacillus polymyxa CR1 AHC21223.1
AIW41134.1
    2
 PPE_03499   Paenibacillus polymyxa E681 ADM71316.1 E0RKV9   2
 cellulase 5A (Cel5A) 3.2.1.4 Paenibacillus polymyxa GS01 ABV08875.1 A9Q741   2
 C1A50_3836   Paenibacillus polymyxa HY96-2 AUS28000.1     2
 C1A50_2484   Paenibacillus polymyxa HY96-2 AUS26651.1     2
 AOU00_05770   Paenibacillus polymyxa J AOK89371.1     2
 PPM_2317 (Cela1)   Paenibacillus polymyxa M1 CCC85254.1     2
 PPM_3757 (Bglc5)   Paenibacillus polymyxa M1 CCI70566.1     2
 RE92_00250   Paenibacillus polymyxa Sb3-1 AJE49587.1     2
 RE92_18560   Paenibacillus polymyxa Sb3-1 AJE52898.1     2
 PPSC2_c2575   Paenibacillus polymyxa SC2 ADO56545.1 E3EJJ5   2
 PPSC2_c4008   Paenibacillus polymyxa SC2 ADO57958.1 E3E5T1   2
 PPSQR21_024100 (BglC)   Paenibacillus polymyxa SQR-21 SQR21 AHM66052.1     2
 PPSQR21_037440   Paenibacillus polymyxa SQR-21 SQR21 AHM67382.1     2
 PPYC1_07015   Paenibacillus polymyxa YC0136 APB70121.1     2
 PPYC2_07365   Paenibacillus polymyxa YC0573 APB74809.1     2
 ASL14_19680   Paenibacillus sp. IHB B 3084 ALP38072.1     2
 endoglucanase (EG5B)   Paenibacillus sp. IHB B 3084 AHA61671.1     2
 endoglucanase (EgL)   Paenibacillus sp. KSM-N115 BAF62084.1 A5A6G0   2
 endoglucanase (EgL)   Paenibacillus sp. KSM-N145 BAF62085.1 A5A6G1   2
 endoglucanase (Egl)   Paenibacillus sp. KSM-N440 BAF62086.1 A5A6G2   2
 endoglucanase (EgL)   Paenibacillus sp. KSM-N659 BAF62087.1 A5A6G3   2
 C0638_20945   Paenibacillus sp. lzh-N1 AUO08830.1     2
 C0638_14795   Paenibacillus sp. lzh-N1 AUO07708.1     2
 HPL003_27305   Paenibacillus terrae HPL-003 AET62173.1     2
 Palpr_1811   Paludibacter propionicigenes WB4 ADQ79950.1 E4T5F6   2
 DSJ_23665   Pantoea stewartii subsp. stewartii DC283 ARF52259.1     2
 GZ59_26180 (CelV)   Pectobacterium atrosepticum 21A AIK14411.1     2
 CVS35_12765   Pectobacterium atrosepticum 36A ATY91160.1     2
 EV46_09525   Pectobacterium atrosepticum JG10-08 AIA70817.1     2
 ECA1981 (CelV)   Pectobacterium atrosepticum SCRI1043 CAG74882.1     2
 OA04_19270 (CelV)   Pectobacterium carotovorum 3-2 AVT58502.1     2
 endoglucanase (CelV2)   Pectobacterium carotovorum ATCC 15713 ACO59152.1 C7T4H6   2
 endoglucanase (CelN1) (fragment)   Pectobacterium carotovorum ATCC 15713 ACO59153.1 C7T4H7   2
 endo-β-1,4-glucanase N (CelN) (fragment) 3.2.1.4 Pectobacterium carotovorum ATROSEPTICA AAC37033.1 Q59394   2
 endoglucanase (CelV4)   Pectobacterium carotovorum N34 ACV51799.1 C9DDS2   2
 endoglucanase (CelN3) (fragment)   Pectobacterium carotovorum N34 ACV51800.1 C9DDS3   2
 endoglucanase (CelV3)   Pectobacterium carotovorum N35 ACO59154.1 C7T4H8   2
 endoglucanase (CelN2) (fragment)   Pectobacterium carotovorum N35 ACO59155.1 C7T4H9   2
 endoglucanase (CelV5)   Pectobacterium carotovorum N47 ACV51801.1 C9DDS4   2
 endoglucanase (CelN4) (fragment)   Pectobacterium carotovorum N47 ACV51802.1 C9DDS5   2
 BJJ97_16795   Pectobacterium carotovorum Polaris ASY77460.1     2
 SCC1_2532 (CelV)   Pectobacterium carotovorum SCC1 ASN85963.1     2
 endo-β-1,4-glucanase V1 3.2.1.4 Pectobacterium carotovorum SCC3193 CAA55823.1 Q59395   2
 endo-β-1,4-glucanase V 3.2.1.4 Pectobacterium carotovorum SCRI193 CAA53592.1 Q47096   2
 BJK05_06530   Pectobacterium carotovorum SK-992-20-13 ASY79671.1     2
 NC16_11725   Pectobacterium carotovorum subsp. brasiliense BC1 APS30351.1     2
 CTV95_02425   Pectobacterium carotovorum subsp. brasiliense BZA12 ATV42374.1     2
 B5S52_10115   Pectobacterium carotovorum subsp. brasiliense SX309 ARA76210.1     2
 endo-β-1,4-glucanase (CelA) 3.2.1.4 Pectobacterium carotovorum subsp. carotovorum LY34 AAC02964.2
AAC02964.1
O31029   2
 PC1_2337   Pectobacterium carotovorum subsp. carotovorum PC1 ACT13369.1 C6DJY6   2
 PCC21_024390   Pectobacterium carotovorum subsp. carotovorum PCC21 AFR03842.1     2
 BCS7_11780   Pectobacterium carotovorum subsp. odoriferum BC S7 AIU88722.1     2
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