Glycoside Hydrolase Family 5 / Subf 2

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (1131); Uniprot accession (275); PDB accession (42); 3D entries (14); cryst (0)
All (1014) Bacteria (845) Eukaryota (155) unclassified (14) Structure (14) Characterized (120)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 endo-β-1,4-glucanase E / 5B (CelE;CJA_2983) (Cel5B) 3.2.1.4 Cellvibrio japonicus Ueda107 ACE84076.1
CAA60493.1
B3PCS3
Q59665
  2
 endo-β-1,4-glucanase B (CelB) (Cel5A;Cel5B) 3.2.1.4 Cellvibrio mixtus ATCC 12120 AAB61462.2 O07653   2
 CBR65_07670   Cellvibrio sp. PSBB006 ARU27326.1     2
 CBR65_04985   Cellvibrio sp. PSBB006 ARU26834.1     2
 B0D95_09905   Cellvibrio sp. PSBB023 AQT60375.1     2
 Cpin_2009   Chitinophaga pinensis DSM 2588 ACU59504.1 C7PCC1   2
 CK934_17930   Chitinophaga sp. MD30 ASZ12701.1     2
 CMC5_057090   Chondromyces crocatus Cm c5 AKT41501.1     2
 CMC5_059560   Chondromyces crocatus Cm c5 AKT41745.1     2
 CAC0706   Clostridium acetobutylicum ATCC 824 AAK78683.1
NP_347343.1
Q97L56   2
 SMB_G0720 (EglA)   Clostridium acetobutylicum DSM 1731 AEI34191.1     2
 CEA_G0717   Clostridium acetobutylicum EA 2018 ADZ19756.1     2
 DK921_09910   Clostridium acetobutylicum LJ4 AWV80402.1     2
 β-1,4-glucanase (Cel5I;Ccel_0428) (Cel5I) 3.2.1.4 [Clostridium] cellulolyticum H10 ACL74811.1
AAL79562.1
B8I5Z4
Q8RLT7
  2
 CCDG5_0576   [Clostridium] cellulosi CDZ23707.1     2
 endoglucanase (Eng5F)   Clostridium cellulovorans BAV13064.1     2
 endo-β-1,4-glucanase 5A (EngF) (Cel5A) 3.2.1.4 Clostridium cellulovorans AAB40891.1 P94622   2
 Clocel_0905   Clostridium cellulovorans 743B ADL50675.1 D9ST59   2
 Clocel_3662   Clostridium cellulovorans 743B ADL53332.1 D9SWQ0   2
 A7L45_18475   Clostridium estertheticum subsp. estertheticum DSM 8809 APC41907.1     2
 endo-β-1,4-glucanase 5A (CelA) (Cel5A) 3.2.1.4 Clostridium josui BAA12826.1
BAA12826.2
Q59290   2
 CSACC_09830 (Cel5A)   Clostridium saccharobutylicum BAS/B3/SW/136 AQR99180.1     2
 CLSA_c09900 (EglA)   Clostridium saccharobutylicum DSM 13864 AGX42001.1     2
 CLOSACC_09830 (Cel5A)   Clostridium saccharobutylicum NCP 195 AQS13168.1     2
 CLOSC_09760 (Cel5A)   Clostridium saccharobutylicum NCP 200 AQR89279.1     2
 CLOBY_10270 (Cel5A)   Clostridium saccharobutylicum NCP 258 AQS08912.1     2
 endo-β-1,4-glucanase (EglA) 3.2.1.4 Clostridium saccharobutylicum P262 AAA23230.1 P15704   2
 Clo1100_1353   Clostridium sp. BNL1100 AEY65590.1     2
 CCU_20020   Coprococcus sp. ART55/1 CBK83458.1 D5HEX5   2
 CCU_25500   Coprococcus sp. ART55/1 CBK83877.1 D5HG44   2
 CYFUS_008414   Cystobacter fuscus DSM 52655 ATB42935.1     2
 CYFUS_001603   Cystobacter fuscus DSM 52655 ATB36189.1     2
 endoglucanase 5A (ChCel5A;CHU_1107) (Cel5A) 3.2.1.4 Cytophaga hutchinsonii ATCC 33406 ABG58383.1 Q11W33   2
 periplasmic endoglucanase 5B (CHU_2103) (Cel5B) 3.2.1.4 Cytophaga hutchinsonii ATCC 33406 ABG59366.1 Q11T98 5IHS[A] 2
 SAMN06298216_2068   Cytophagales bacterium TFI 002 SOE21610.1     2
 DTL3_1188   Defluviitoga tunisiensis CEP78490.1     2
 endocellulase (Cel5)   Deinococcus cellulosilyticus 5516J-15 AKN19928.1     2
 Dd1591_1529   Dickeya chrysanthemi Ech1591 ACT06384.1 C6CF34   2
 endo-β-1,4-glucanase (Cel5Z) 3.2.1.4 Dickeya chrysanthemi PY35 AAF18152.1 Q9REW0   2
 endo-β-1,4-glucanase Z (CelZ;EgZ;Dda3937_02793) (Cel5A=Cel5Z) 3.2.1.4 Dickeya dadantii 3937 ADM99099.1
CAA68604.1
P07103 1EGZ[A,B,C] 2
 DDI_2600   Dickeya dianthicola RNS04.9 ATO33768.1     2
 DDI_0695   Dickeya dianthicola RNS04.9 ATO31863.1     2
 CVE23_14355   Dickeya fangzhongdai DSM 101947 ATZ95058.1     2
 Dd703_1886   Dickeya paradisiaca Ech703 ACS85678.1 C6C568   2
 BJD21_19575   Dickeya solani D s0432-1 AUH10464.1     2
 A4U42_01465   Dickeya solani IPO 2222 ANE74123.1     2
 BJJ98_19545   Dickeya solani PPO 9019 AUH14400.1     2
 D083_0932   Dickeya solani RNS 08.23.3.1.A AUC41282.1     2
 W909_12595   Dickeya zeae EC1 AJC66868.1     2
 Dd586_1489   Dickeya zeae Ech586 ACZ76357.1 D2BWX3   2
 C1O30_13580   Dickeya zeae MS2 AUQ26034.1     2
 DN752_14120   Echinicola strongylocentroti MEBiC08714 AWW31171.1     2
 Echvi_1632   Echinicola vietnamensis DSM 17526 AGA77897.1     2
 AV903_20125   Erwinia tracheiphila MDcuke AXF77819.1     2
 EUBELI_20587   [Eubacterium] eligens ATCC 27750 ACR73731.1 C4Z6Y9   2
 EUBREC_0616   [Eubacterium] rectale ATCC 33656 ACR74405.1 C4ZCQ0   2
 EUR_02280   [Eubacterium] rectale DSM 17629 CBK89462.1 D6E222   2
 ERE_23730   [Eubacterium] rectale M104/1 CBK94241.1 D4JKU4   2
 EUS_00270   [Eubacterium] siraeum 70/3 CBK95395.1 D4JQM6   2
 ES1_04480   [Eubacterium] siraeum V10Sc8a CBL33590.1 D4MIK7   2
 AALO17_05750 (fragment)   Faecalibaculum rodentium Alo17 AMK53709.1     2
 AALO17_05740 (fragment)   Faecalibaculum rodentium Alo17 AMK53708.1     2
 Fisuc_1224 / FSU_1685 3.2.1.4 Fibrobacter succinogenes subsp. succinogenes S85 ACX74827.1
ADL26286.1
C9RQJ1   2
 Fisuc_1661 / FSU_2150   Fibrobacter succinogenes subsp. succinogenes S85 ACX75256.1
ADL25349.1
C9RRS0   2
 Fisuc_2011 / FSU_2534   Fibrobacter succinogenes subsp. succinogenes S85 ACX75598.1
ADL25634.1
C9RJ81   2
 endoglucanase (partial) 3.2.1.4 Fibrobacter succinogenes subsp. succinogenes S85 AAC06197.1 O66065   2
 cellulase (Fisuc_2364;FSU_2914) (Cel5H) 3.2.1.4 Fibrobacter succinogenes subsp. succinogenes S85 ABU45500.1
ACX75950.1
ADL27061.1
A7UG69   2
 FLA_2145   Filimonas lacunae NBRC 104114 BAV06130.1     2
 MY04_0191 (Cel5B)   Flammeovirga sp. MY04 ANQ47573.1     2
 D770_26615   Flammeovirgaceae bacterium 311 AHM63566.1     2
 D770_06795   Flammeovirgaceae bacterium 311 AHM59622.1     2
 DVK85_01130   Flavobacterium arcticum SM1502 AXG72906.1     2
 BB050_02617 (EglS)   Flavobacterium johnsoniae GSE09 AOC95714.1     2
 Fjoh_4946   Flavobacterium johnsoniae UW101 ABQ07945.1 A5FA24   2
 ALW18_03010   Flavobacterium psychrophilum Z1 AOE54289.1     2
 AMR72_03010   Flavobacterium psychrophilum Z2 ALM50669.1     2
 FK004_17195   Flavobacterium sp. AJ004 AWG26841.1     2
 HYN56_24350   Flavobacterium sp. HYN0056 AWK07189.1     2
 HYN59_00930   Flavobacterium sp. HYN0059 AWH83763.1     2
 HYN86_20395   Flavobacterium sp. HYN0086 AXB58816.1     2
 DI487_13690   Flavobacterium sp. MEBiC07310 AWM14796.1     2
 endo-β-1,4-glucanase (CelA;GsCelA) 3.2.1.4 Geobacillus sp. 70PC53 ACJ60856.1 C5H6X3 4XZB[A]
4XZW[A]
2
 endoglucanase   Geobacillus stearothermophilus CICC-20649 ADO21451.1 E3V048   2
 C7S20_04585   Gramella sp. SH35 AVR44599.1     2
 endoglucanase (Cel5A)   Gynuella sunshinyii YC6258 AII80614.1     2
 YC6258_05810   Gynuella sunshinyii YC6258 AJQ97838.1     2
 YC6258_02995   Gynuella sunshinyii YC6258 AJQ95033.1     2
 endoglucanase (Cel5;HCH_03914) 3.2.1.4 Hahella chejuensis KCTC 2396 ABC30636.1 Q2SFD8   2
 SD1D_0239 (EglA)   Herbinix luporum SD1D CUH91792.1     2
 HVS_14300 (fragment)   Herbivorax saccincola GGR1 AUG58721.1     2
 HVS_12420 (Cel5A)   Herbivorax saccincola GGR1 AUG58357.1     2
 DDQ68_08965   Hymenobacter nivis NBRC 111535 AWM35364.1     2
 AXW84_14545   Hymenobacter sp. PAMC 26628 AMJ66514.1     2
 Hsw_1037   Hymenobacter swuensis DY53 AHJ96632.1     2
 BN2497_11653   Janthinobacterium sp. CG23_2 CUI24051.1     2
 AOZ06_10145   Kibdelosporangium phytohabitans KLBMP1111 ALG07233.1     2
 ORF   Kibdelosporangium sp. MJ126-NF4 CTQ95794.1     2
 B7C62_30465   Kitasatospora albolonga YIM 101047 ARF76115.1     2
 Kfla_1714   Kribbella flavida DSM 17836 ADB30809.1 D2PNF7   2
 cellulase, partial (Cel1) (fragment)   Lactobacillus plantarum UBL1 AOO87088.1     2
Top




Last update: 2018-08-08 © Copyright 1998-2018
AFMB - CNRS - Université d'Aix-Marseille