Glycoside Hydrolase Family 5 / Subf 2

Activities in Sub Family	Chitosanase (EC 3.2.1.132); Endo-β-1,4-glucanase (EC 3.2.1.4); Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73); Endo-β-1,4-xylanase (EC 3.2.1.8);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) ₈ barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (10); Uniprot accession (147); PDB accession (47); 3D entries (17); cryst (0)

Summary

Download GH5_2 (2298) Taxonomic display Structure (17) Characterized (129)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
glycoside hydrolase family 5		uncultured bacterium contig00123	AGS51879.1			2
CelA84		uncultured bacterium fosmid pJB84D8	AIF26716.1			2
Firmicute1046_3160		uncultured Firmicutes bacterium	QGT51240.1			2
endoglucanase, partial		uncultured Saccharophagus sp.	WRM49288.1			2
RF679_07820		Undibacterium sp. 20NA77.5	WMW82180.1			2
LPB138_13260		Urechidicola croceus LPB0138	AOW21587.1			2
LPB138_02890		Urechidicola croceus LPB0138	AOW19691.1			2
HZI73_17905		Vallitalea pronyensis FatNI3	QUI24052.1			2
HUT12_15985		Verrucosispora sp. NA02020	QKW14137.1			2
HUT12_15160		Verrucosispora sp. NA02020	QKW17201.1			2
O3597_11585		Verrucosispora sp. WMMA2044	WBB51062.1			2
O7597_26540		Verrucosispora sp. WMMC514	WBB90494.1			2
O7624_29130		Verrucosispora sp. WMMD1129	WFE48127.1			2
O7601_23180		Verrucosispora sp. WMMD573	WBB53444.1			2
BSQ33_18105		Vibrio gazogenes ATCC 43942	ASA58289.1			2
MKS89_17635		Vibrio gazogenes PB1	USP16203.1			2
R8Z52_19190		Vibrio porteresiae DSM 19223 MSSRF30	WPC76655.1			2
RND59_19470		Vibrio ruber HNIBRBA4764	WNJ97381.1			2
Vspart_04132 (Celz_2)		Vibrio spartinae 3.6	QMV16727.1			2
endo-β-1,4-glucanase (Cel5A) (Cel5A)	3.2.1.4	Vibrio xiamenensis G21	ADJ93836.1	D8V609		2
WAL19_34880		Waltera intestinalis 19YCFAH0.3Co2	BEU19652.1			2
H9Q76_05765		Wujia chipingensis NSJ-4	QNM00780.1			2
H9Q76_01310		Wujia chipingensis NSJ-4	QNL99979.1			2
J7S26_07230		Xiamenia xianingshaonis zg-886	QTU84139.1			2
zobellia_3703 (BglC)		Zobellia galactanivorans DsijT	CAZ97841.1			2
Q5W13_23910		Zobellia laminariae AS94	WKX76522.1			2
carboxylmethylcellulase (Cell7)		Zobellia sp. B2	WIV69120.1			2
PBT91_01015		Zunongwangia sp. HGR-M22	WBL25887.1			2
INR75_03070		Zunongwangia sp. SCSIO 43204	UAB85029.1			2
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