Activities in Sub Family	Chitosanase (EC 3.2.1.132); Endo-β-1,4-glucanase (EC 3.2.1.4); Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73); Endo-β-1,4-xylanase (EC 3.2.1.8);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (10); Uniprot accession (147); PDB accession (47); 3D entries (17); cryst (0)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
endoglucanase (EglS)		Bacillus velezensis RS1	AUB45040.1			2
BVS141_18850 (EglS)		Bacillus velezensis S141	BBA76409.1			2
A5891_09010		Bacillus velezensis S3-1	ANS38519.1			2
BVELS4_01900 (EglS)		Bacillus velezensis S4	QIR33158.1			2
CHN56_00337 (EglS)		Bacillus velezensis SCDB 291	ASS60881.1			2
CLI97_03910 (EglS)		Bacillus velezensis SCGB 1	ATC53134.1			2
CLI98_03744 (EglS)		Bacillus velezensis SCGB 574	ATD76966.1			2
C1N92_00760		Bacillus velezensis SGAir0473	AWQ13510.1			2
V529_17790 (BglC)		Bacillus velezensis SQR9	AHZ15805.1			2
S100072_01973		Bacillus velezensis SRCM100072	ASB53309.1			2
DXY21_03136		Bacillus velezensis SRCM101368	QHM89061.1			2
S101413_02134		Bacillus velezensis SRCM101413	ASB65581.1			2
C7M19_00124 (EglS)		Bacillus velezensis SRCM102741	QHK05195.1			2
C7M20_01842 (EglS)		Bacillus velezensis SRCM102742	QHK10718.1			2
C7M21_02706 (EglS)		Bacillus velezensis SRCM102743	QHK15437.1			2
C7M22_03294 (EglS)		Bacillus velezensis SRCM102744	QHK65337.1			2
C7M24_01991 (EglS)		Bacillus velezensis SRCM102746	QHL94005.1			2
C7M25_03156 (EglS)		Bacillus velezensis SRCM102747	QHL98929.1			2
DBK22_00969 (EglS)		Bacillus velezensis SRCM102752	QHM79132.1			2
C7M18_03335 (EglS)		Bacillus velezensis SRCM102755	QHK04438.1			2
ETK69_10500		Bacillus velezensis SRCM103616	QAW50126.1			2
ES966_10125		Bacillus velezensis SRCM103691	QAV92521.1			2
ETA12_10130		Bacillus velezensis SRCM103788	QAW24951.1			2
BLL65_09625		Bacillus velezensis sx01604	AQZ73217.1			2
F0M21_09250		Bacillus velezensis SYP-B637	QEO30804.1			2
CEG11_09415		Bacillus velezensis T20E-257	ASF55305.1			2
CG798_14945		Bacillus velezensis TB1501	ASP26388.1			2
AJ82_10290		Bacillus velezensis TrigoCor1448	AHK49356.1			2
D069_1727 (fragment)		Bacillus velezensis UCMB5007	QDF52438.1			2
RBAU_1784 (EglS)		Bacillus velezensis UCMB5033	CDG29752.1			2
BAM5036_1746 (EglS)		Bacillus velezensis UCMB5036	CCP21786.1			2
FIM06_1728 (fragment)		Bacillus velezensis UCMB5044	QDF48792.1			2
BASU_1764 (EglS)		Bacillus velezensis UCMB5113	CDG26057.1			2
HC661_18130		Bacillus velezensis UCMB5140	QJC92630.1			2
E0E07_08705		Bacillus velezensis UTB96	QBK22500.1			2
C6P48_09830		Bacillus velezensis VCC-2003	AVM08503.1			2
HUW56_02630		Bacillus velezensis WLYS23	QKX12347.1			2
CXB71_09415		Bacillus velezensis WRN014	QDK90074.1			2
BANAU_1935 (BglC)		Bacillus velezensis YAU B9601-Y2	CCG49956.1			2
AAV30_10320		Bacillus velezensis YJ11-1-4	AKF76524.1			2
ETZ92_004745		Bacillus velezensis ZeaDK315Endobac16	QEQ03602.1			2
D3N19_09300		Bacillus velezensis ZF2	AXY70422.1			2
cellulase (CelA10)	3.2.1.4	bacterium enrichment culture clone CelA10	ACR23656.1	C5HG53		2
endoglucanase (Cel5) (Cel5A)		bacterium enrichment culture clone FV-Cel5A	AEL31246.1			2
K6V21_01965		Bacteroides cellulosilyticus BFG-250	UBD70222.1			2
NXW88_02250		Bacteroides cellulosilyticus BFG-371	UVP51786.1			2
INE78_01642 (EglS)		Bacteroides cellulosilyticus CL06T03C01	QUT89667.1			2
NWT25_02120		Bacteroides cellulosilyticus PL2022	UWZ90046.1			2
BcellWH2_02030 (EglS)		Bacteroides cellulosilyticus WH2	ALJ59275.1			2
JXR92_001680		Bacteroides humanifaecis KGMB07931	UDB44394.1			2
LIX30_01675		Bacteroides humanifaecis KGMB10229	UDL12022.1			2
DYI28_17305		Bacteroides ovatus 3725 D1 iv	QDM12662.1			2
Bovatus_03047 (EglS)		Bacteroides ovatus ATCC 8483	ALJ47655.1			2
NQ517_04025		Bacteroides ovatus ATCC 8483	UWN94253.1			2
NXW74_04615		Bacteroides ovatus BFG-126	UVR11611.1			2
NXW64_04695		Bacteroides ovatus BFG-177	UVO70393.1			2
NXV93_04465		Bacteroides ovatus BFG-224	UVR45745.1			2
NXV29_04740		Bacteroides ovatus BFG-261	UVR40875.1			2
NXW52_09870		Bacteroides ovatus BFG-464	UVP13485.1			2
INE80_01261 (EglS)		Bacteroides ovatus CL06T03C20	QUT79284.1			2
I6J65_13330		Bacteroides ovatus FDAARGOS_1235	QRQ59075.1			2
FOC41_16510		Bacteroides ovatus FDAARGOS_733	QGT74225.1			2
RJT06_16860		Bacteroides ovatus H-1813	MDV3118213.1			2
BACOV975_00809		Bacteroides ovatus V975	SCV07053.1			2
BOVAC1_5192		Bacteroides ovatus VPIC145	CAG9870837.1			2
NQ488_05930		[Bacteroides] pectinophilus ATCC 43243	UWN96836.1			2
EYA81_06420		Bacteroides sp. A1C1	QBJ17986.1			2
NXV86_02045		Bacteroides sp. BFG-257	UVO98852.1			2
H1A11_13350		Bacteroides sp. CACC 737	QMI79433.1			2
NQ505_06170		Bacteroides sp. D2	UWO01017.1			2
ITJ87_01505		Bacteroides sp. HF-162	QPH58292.1			2
H8796_04415		Bacteroides sp. M10	QNL39857.1			2
NQ510_02090		Bacteroides uniformis ATCC 8492	UWO07773.1			2
NXX72_01250		Bacteroides uniformis BFG-227	UVS17643.1			2
INE75_02951 (EglS)		Bacteroides uniformis CL03T12C37	QUU00598.1			2
INE83_00503 (EglS)		Bacteroides uniformis CL06T03C05	QUT65069.1			2
INE84_01762 (EglS)		Bacteroides uniformis CL06T06C18	QUT62082.1			2
INE90_00435 (EglS) (fragment)		Bacteroides uniformis CL11T00C07	QUT33701.1			2
INE90_00432 (fragment)		Bacteroides uniformis CL11T00C07	QUT33698.1			2
I6G58_02755		Bacteroides uniformis FDAARGOS_901	QQA30548.1			2
QWU49_02090		Bacteroides uniformis JCM5828	WNG09923.1			2
Bun01g_02670		Bacteroides uniformis NBRC 113350	BBK85897.1			2
KQP54_11720		Bacteroides uniformis VPI-3537	UYU51478.1			2
FQN58_21180		Bacteroides xylanisolvens APCS1/XY	QUR46759.1			2
P2T61_10905		Bacteroides xylanisolvens AY11-1	WET88445.1			2
NXW81_04270		Bacteroides xylanisolvens BFG-319	UVQ13590.1			2
NXX95_04320		Bacteroides xylanisolvens BFG-514	UVP26562.1			2
INE92_03593 (EglS)		Bacteroides xylanisolvens CL11T00C03	QUT31543.1			2
INE93_03674 (EglS)		Bacteroides xylanisolvens CL11T00C41	QUT26196.1			2
GFH35_14090		Bacteroides xylanisolvens funn3	QRN02187.1			2
FKZ68_03940		Bacteroides xylanisolvens H207	QDH57502.1			2
BXY_21090		Bacteroides xylanisolvens XB1A	CBK67187.1			2
BANAN_06350		Bifidobacterium animalis subsp. animalis ATCC 25527	AFI63478.1			2
CNCMI4602_1260		Bifidobacterium animalis subsp. animalis CNCM I-4602	AYN24105.1			2
A4U98_07950		Bifidobacterium animalis subsp. animalis YL2	ARE60173.1			2
LDH92_06575 (fragment)		Bifidobacterium animalis subsp. lactis 19-D-1	UBZ02305.1			2
BLAC_06500 (fragment)		Bifidobacterium animalis subsp. lactis ATCC 27673	AGW85477.1			2
I5Q88_02190		Bifidobacterium animalis YL2	QQQ90661.1			2
M2855_05445		Bifidobacterium animalis YL2	UQE62846.1			2
BcFMB_00600		Bifidobacterium choerinum FMB-1	ATU19681.1			2
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