Activities in Sub Family	Chitosanase (EC 3.2.1.132); Endo-β-1,4-glucanase (EC 3.2.1.4); Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73); Endo-β-1,4-xylanase (EC 3.2.1.8);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (10); Uniprot accession (147); PDB accession (47); 3D entries (17); cryst (0)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
JRI60_12180		Archangium violaceum SDU8	QRO02487.1			2
ATOBIA_10440		Atopobiaceae bacterium P1	BCV18962.1			2
QP953_08965		Aureispira sp. CCB-E	WMX16498.1			2
IL989_08985		Bacillus amyloliquefaciens	QOQ56755.1			2
cellulase		Bacillus amyloliquefaciens 157	AVC04903.1			2
M1M81_09215		Bacillus amyloliquefaciens A15.1	UPV84719.1			2
BAALB65_09790		Bacillus amyloliquefaciens ALB65	AWM44312.1			2
DDT09_09835		Bacillus amyloliquefaciens ALB69	AWM48134.1			2
DDT10_09310		Bacillus amyloliquefaciens ALB79	AWM51868.1			2
endoglucanase		Bacillus amyloliquefaciens AMS1	AKS29707.1			2
A1R12_09055		Bacillus amyloliquefaciens B15	AMR50503.1			2
NO220_09365		Bacillus amyloliquefaciens B408	UUA78769.1			2
endo-β-1,4-glucanase (EgL)		Bacillus amyloliquefaciens BY-5	AMW90767.1			2
IXY24_09410		Bacillus amyloliquefaciens BZR 277	QPG23445.1			2
endo-β-1,4-glucanase (EgL)		Bacillus amyloliquefaciens C9	QEX95298.1			2
J4A01_09125		Bacillus amyloliquefaciens CAS02	UUO21544.1			2
U471_18630		Bacillus amyloliquefaciens CC178	AGZ56565.1			2
KMZ31_09145		Bacillus amyloliquefaciens CQN-2	UQB84025.1			2
I5367_09130		Bacillus amyloliquefaciens DGL1	QPQ41246.1			2
FNS63_03410		Bacillus amyloliquefaciens DH8030	QEQ52044.1			2
KZA05_14160		Bacillus amyloliquefaciens EA19	QXX28210.1			2
E3U39_21010		Bacillus amyloliquefaciens FS1092	QBQ47004.1			2
J5X95_18430		Bacillus amyloliquefaciens GKT04	QYC32921.1			2
MY487_09185		Bacillus amyloliquefaciens GL18	UPM48809.1			2
I3J23_18860		Bacillus amyloliquefaciens GXU-1	QSZ44784.1			2
DKG78_09950		Bacillus amyloliquefaciens HM618	QOH66468.1			2
GlnC		Bacillus amyloliquefaciens HYM-12	WJJ67088.1			2
endo-β-1,4-glucanase		Bacillus amyloliquefaciens IARI-SP-2	AGW99978.1			2
BAINH2_09115		Bacillus amyloliquefaciens INH2-4b	QOE02189.1			2
KSO_010315		Bacillus amyloliquefaciens IT-45	AGF27558.1			2
BAJP3042_09540		Bacillus amyloliquefaciens JP3042	QZT42720.1			2
BAJP3144_10215		Bacillus amyloliquefaciens JP3144	QZY31001.1			2
KHU1_1621		Bacillus amyloliquefaciens KHG19	AJK65578.1			2
NMK97_09485		Bacillus amyloliquefaciens KNU-28	UTQ09957.1			2
SB45_09085		Bacillus amyloliquefaciens L-H15	AJH24169.1			2
XM40_09090		Bacillus amyloliquefaciens L-S60	AKD22364.1			2
U722_09575		Bacillus amyloliquefaciens LFB112	AHC42348.1			2
BSF20_16750		Bacillus amyloliquefaciens LM2303	APH49957.1			2
LUA14_10510		Bacillus amyloliquefaciens LS1-002-014s	UHH04931.1			2
cellulase (fragment)		Bacillus amyloliquefaciens MBAA3	AHJ80840.1			2
AVM03_03620		Bacillus amyloliquefaciens MBE1283	ALV01512.1			2
O7R04_08950		Bacillus amyloliquefaciens MBLB 0692	WBL41003.1			2
NUW85_02605		Bacillus amyloliquefaciens MBLB0692	WEU36757.1			2
P1K87_09285		Bacillus amyloliquefaciens MG-2	WER36259.1			2
endo-1,4-β-glucanase precursor		Bacillus amyloliquefaciens MN-13	AVI57374.1			2
MNY35_02035		Bacillus amyloliquefaciens MN-13	WGK42541.1			2
endo-1,4-β-glucanase precursor		Bacillus amyloliquefaciens MN-8	AVI57373.1			2
BAMOH1_09245		Bacillus amyloliquefaciens MOH1-5b	QOE05899.1			2
QQW99_09135		Bacillus amyloliquefaciens N2B2	WIX31009.1			2
endoglucanase (EglS)		Bacillus amyloliquefaciens PK1	AUB45039.1			2
endoglucanase (EglII)	3.2.1.4	Bacillus amyloliquefaciens PSM 3.1	ADC54852.1	D3Y2F0		2
HT132_11430		Bacillus amyloliquefaciens R8-25	QKP74283.1			2
AS588_06260		Bacillus amyloliquefaciens S499	AMP31635.1			2
KHS93_09090		Bacillus amyloliquefaciens SN16-1	QVV95581.1			2
cellulase		Bacillus amyloliquefaciens T3	AWB51882.1			2
LT978_10075		Bacillus amyloliquefaciens TL106	USP42461.1			2
BAMY6614_13370		Bacillus amyloliquefaciens UMAF6614	AMQ74283.1			2
BAMY6639_00620		Bacillus amyloliquefaciens UMAF6639	AMQ71229.1			2
endoglucanase A (EngA)	3.2.1.4	Bacillus amyloliquefaciens UMAS1002	AAL99668.1	Q8RPQ6		2
BACIH_1837		Bacillus amyloliquefaciens V167	QEY93577.1			2
BACIT_3901		Bacillus amyloliquefaciens V417	QEY91658.1			2
LXM91_09295		Bacillus amyloliquefaciens W0101	UOI92275.1			2
HNO12_09155		Bacillus amyloliquefaciens WF02	QJW63008.1			2
MK616_09465		Bacillus amyloliquefaciens WF2020	UMR28097.1			2
OU987_09225		Bacillus amyloliquefaciens WH1	WAI11341.1			2
BSO20_02700		Bacillus amyloliquefaciens WS-8	APQ49018.1			2
J4048_09325		Bacillus amyloliquefaciens XJ5	QTG86945.1			2
BAMY_08970		Bacillus amyloliquefaciens Y14	APB82271.1			2
MUS_2161 (BglC)		Bacillus amyloliquefaciens Y2	AFJ62120.1			2
LOZ87_09355		Bacillus amyloliquefaciens ZF57	UFK58802.1			2
FGF55_09690		Bacillus amyloliquefaciens ZJU1	QDP88508.1			2
F5K02_10680		Bacillus amyloliquefaciens ZKY01	UNE51288.1			2
BaGK_15910 (fragment)		Bacillus atrophaeus GQJK17	ASS72344.1			2
D068_cds30840 (fragment)		Bacillus atrophaeus UCMB-5137	AKL85635.1			2
EFK13_10005		Bacillus cabrialesii TE3	UQE81032.1			2
endo-β-1,4-glucanase (fragment)		Bacillus cereus IARI-SP-7	AGW99984.1			2
C1T25_10255		Bacillus cereus MBGJa3	AUZ28685.1			2
BGLY_2367 (Bglc2)		Bacillus glycinifermentans	SCA86190.1			2
COP00_03840		Bacillus glycinifermentans KBN06P03352	ATH91857.1			2
MW696_03190		Bacillus glycinifermentans MGMM1	UOY89265.1			2
EQZ20_11665		Bacillus glycinifermentans SRCM103574	QAT65500.1			2
QYM22_11965		Bacillus glycinifermentans SRCM12603	WKB79679.1			2
O0R52_09975		Bacillus halotolerans B13	WAT23248.1			2
FLQ13_17995		Bacillus halotolerans F41-3	QDK69171.1			2
OMK57_10185		Bacillus halotolerans HMB20199	UZD53337.1			2
QRD86_10690		Bacillus halotolerans KF17	WJE44988.1			2
QNH41_09960		Bacillus halotolerans LN2	WHY26311.1			2
JYG31_09965		Bacillus halotolerans MBH1	QVN29470.1			2
NLV76_10210		Bacillus halotolerans MEC_B301	UTL74547.1			2
NLW79_10070		Bacillus halotolerans MEC_B334	UTL78545.1			2
I7X10_08895		Bacillus halotolerans P1	QPZ43917.1			2
C2H92_05645		Bacillus halotolerans PK3_4	UQZ46225.1			2
RYX39_10240		Bacillus halotolerans Q2H2	WOC58764.1			2
NPA28_10060		Bacillus halotolerans S-5	UUI86189.1			2
QPL78_10260		Bacillus halotolerans Tehuacan_S4	WIG48837.1			2
NDR85_10115		Bacillus halotolerans XE48	UYO33869.1			2
ICJ61_10455		Bacillus halotolerans XH-1	QNS22171.1			2
DIC78_00115		Bacillus halotolerans ZB201702	AZV47552.1			2
RA179_10085		Bacillus halotolerans ZSTM2175/A	WPC82537.1			2
NM058_12215		Bacillus inaquosorum 1HC-NA	UTX03959.1			2
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