Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC 3.2.1.21); xylan 1,4-β-xylosidase (EC 3.2.1.37); β-glucosylceramidase (EC 3.2.1.45); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,3-β-glucosidase (EC 3.2.1.58); glucan 1,4-β-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin β-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (17817); Uniprot accession (2560); PDB accession (106); 3D entries (34); cryst (4)
All (16969) Archaea (94) Bacteria (15784) Eukaryota (990) Viruses (1) unclassified (100) Structure (34 - 4 cryst) Characterized (295)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 158 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 L083_1586   Actinoplanes sp. N902-109 AGL15096.1    
 L083_1755 (NagA)   Actinoplanes sp. N902-109 AGL15265.1    
 L083_2146 (BglX)   Actinoplanes sp. N902-109 AGL15656.1    
 L083_2625   Actinoplanes sp. N902-109 AGL16135.1    
 L083_2754   Actinoplanes sp. N902-109 AGL16264.1    
 L083_3243   Actinoplanes sp. N902-109 AGL16753.1    
 L083_4236   Actinoplanes sp. N902-109 AGL17746.1    
 L083_4654   Actinoplanes sp. N902-109 AGL18164.1    
 L083_6099   Actinoplanes sp. N902-109 AGL19609.1    
 L083_6554   Actinoplanes sp. N902-109 AGL20064.1    
 L083_7020   Actinoplanes sp. N902-109 AGL20530.1    
 L083_4111   Actinoplanes sp. N902-109 AGL17621.1    
 L083_5876   Actinoplanes sp. N902-109 AGL19386.1    
 ACWT_6438   Actinoplanes sp. SE50 ATO85853.1    
 ACWT_2301   Actinoplanes sp. SE50 ATO81716.1    
 ACWT_2606 (fragment)   Actinoplanes sp. SE50 ATO82021.1    
 ACWT_7279   Actinoplanes sp. SE50 ATO86694.1    
 ACWT_2353   Actinoplanes sp. SE50 ATO81768.1    
 ACWT_1289   Actinoplanes sp. SE50 ATO80704.1    
 ACWT_1399   Actinoplanes sp. SE50 ATO80814.1    
 ACWT_6295   Actinoplanes sp. SE50 ATO85710.1    
 ACPL_1410 (BglK)   Actinoplanes sp. SE50/110 AEV82307.1
SLL98111.1
   
 ACPL_1520 (NagA)   Actinoplanes sp. SE50/110 AEV82417.1
SLL98222.1
   
 ACPL_2940 (possible fragment)   Actinoplanes sp. SE50/110 AEV83835.1
SLL99429.1
   
 ACPL_6428 (BglX)   Actinoplanes sp. SE50/110 AEV87310.1
SLM03123.1
   
 ACPL_6569   Actinoplanes sp. SE50/110 AEV87451.1
SLM03267.1
   
 ACPL_2428   Actinoplanes sp. SE50/110 AEV83323.1
SLL99124.1
   
 ACPL_2480   Actinoplanes sp. SE50/110 AEV83375.1
SLL99176.1
   
 ACPL_7409   Actinoplanes sp. SE50/110 AEV88289.1
SLM04112.1
   
 SAMN04489717_2242   Actinopolymorpha singaporensis DSM 22024 SDS29728.1    
 SAMN04489717_2190   Actinopolymorpha singaporensis DSM 22024 SDS28184.1    
 SAMN04489717_2793   Actinopolymorpha singaporensis DSM 22024 SDS46973.1    
 CDG81_08555   Actinopolyspora erythraea YIM 90600 ASU78334.1    
 CDG81_06555   Actinopolyspora erythraea YIM 90600 ASU78027.1    
 CDG81_01400   Actinopolyspora erythraea YIM 90600 ASU80737.1    
 CDG81_10515   Actinopolyspora erythraea YIM 90600 ASU81029.1    
 CDG81_10545   Actinopolyspora erythraea YIM 90600 ASU81031.1    
 Amir_1826   Actinosynnema mirum DSM 43827 ACU35774.1 C6WE31  
 Amir_1982   Actinosynnema mirum DSM 43827 ACU35930.1 C6WFJ5  
 Amir_2168   Actinosynnema mirum DSM 43827 ACU36113.1 C6WI70  
 β-glucosidase (BglAm;Amir_2978) 3.2.1.21 Actinosynnema mirum DSM 43827 ACU36898.1 C6WRQ6  
 Amir_4021   Actinosynnema mirum DSM 43827 ACU37884.1 C6WFU8  
 Amir_4612   Actinosynnema mirum DSM 43827 ACU38445.1 C6WLQ2  
 Amir_4963   Actinosynnema mirum DSM 43827 ACU38789.1 C6WQU9  
 Amir_0273   Actinosynnema mirum DSM 43827 ACU34242.1 C6WFB0  
 Amir_4872   Actinosynnema mirum DSM 43827 ACU38698.1 C6WQK8  
 CNX65_11070   Actinosynnema pretiosum X47 ATE53768.1    
 CNX65_22935   Actinosynnema pretiosum X47 ATE55782.1    
 CNX65_09900   Actinosynnema pretiosum X47 ATE53565.1    
 CNX65_24095   Actinosynnema pretiosum X47 ATE58354.1    
 CNX65_01290   Actinosynnema pretiosum X47 ATE52089.1    
 CNX65_24475   Actinosynnema pretiosum X47 ATE56038.1    
 CNX65_20135   Actinosynnema pretiosum X47 ATE55306.1    
 CNX65_09115   Actinosynnema pretiosum X47 ATE53435.1    
 ADH66_13945   Acutalibacter muris KB18 ASB41663.1    
 ADH66_06455   Acutalibacter muris KB18 ASB40334.1    
 ADH66_11300   Acutalibacter muris KB18 ASB41189.1    
 ADH66_02435   Acutalibacter muris KB18 ASB39616.1    
 AEQU_2010   Adlercreutzia equolifaciens DSM 19450 BAN77979.1    
 TKWG_14580   Advenella kashmirensis WT001 AFK62972.1    
 MIM_c16440 (NagZ)   Advenella mimigardefordensis DPN7 AHG63727.1    
 Aeqsu_2742   Aequorivita sublithincola DSM 14238 AFL82193.1    
 AP3564_06510   Aeribacillus pallidus KCTC3564 ASS92288.1    
 AWM72_06325   Aerococcus sanguinicola CCUG43001 AMB94403.1    
 AWM72_03455   Aerococcus sanguinicola CCUG43001 AMB94947.1    
 AWM72_05450   Aerococcus sanguinicola CCUG43001 AMB94239.1    
 AWM72_08740 (fragment)   Aerococcus sanguinicola CCUG43001 AMB94838.1    
 AWM74_02695   Aerococcus urinaeequi CCUG28094 AMB97212.1    
 AWM74_05590   Aerococcus urinaeequi CCUG28094 AMB97737.1    
 APT62_02015   Aerococcus urinaeequi USDA-ARS-USMARC-56713 ALZ87295.1    
 APT62_08530   Aerococcus urinaeequi USDA-ARS-USMARC-56713 ALZ88484.1    
 AWM75_03160   Aerococcus urinaehominis CCUG42038B AMB99060.1    
 AWM75_03870   Aerococcus urinaehominis CCUG42038B AMB99193.1    
 AWM75_01260   Aerococcus urinaehominis CCUG42038B AMB98705.1    
 SAMN06295964_3115   Aeromicrobium choanae 9H-4 SKB10129.1    
 β-glucosidase (EryBI) 3.2.1.21 Aeromicrobium erythreum AAU93797.1 Q5Y9H4  
 AERYTH_15870   Aeromicrobium erythreum AR18 ALX06068.1    
 BOQ57_13780   Aeromonas aquatica MX16A APJ15926.1    
 VI35_10145   Aeromonas caviae 8LM ATP90572.1    
 CK627_12380   Aeromonas dhakensis KN-Mc-6U21 ASX11519.1    
 AH4AK4_1957   Aeromonas hydrophila 4AK4 AHE49412.1    
 VU14_08290   Aeromonas hydrophila AH10 AKA16864.1    
 TK34_08400   Aeromonas hydrophila AHNIH1 ANT67484.1    
 RY45_14135   Aeromonas hydrophila AL06-06 AJQ55163.1    
 V428_14770   Aeromonas hydrophila AL09-71 AHX33289.1    
 AhyD4_08545   Aeromonas hydrophila D4 ALZ79637.1    
 A9258_08275   Aeromonas hydrophila GYK1 ANR99615.1    
 V469_08320   Aeromonas hydrophila J-1 AJE35886.1    
 AS145_08790   Aeromonas hydrophila JBN2301 ALQ62975.1    
 AHML_14270   Aeromonas hydrophila ML09-119 AGM44624.1    
 U876_08305   Aeromonas hydrophila NJ-35 AKJ34087.1    
 V429_14790   Aeromonas hydrophila pc104A AHX70089.1    
 AHA_2689   Aeromonas hydrophila subsp. hydrophila ATCC 7966 ABK38668.1 A0KLP6  
 B224_2473   Aeromonas media WS AHX61067.1    
 B224_1238   Aeromonas media WS AHX60168.1    
 CHQ57_08720   Aeromonas salmonicida A527 ATU97523.1    
 CE456_15330   Aeromonas salmonicida S121 ASI23802.1    
 CE463_15350   Aeromonas salmonicida S44 ASI28121.1    
 CE462_14300   Aeromonas salmonicida S68 ASI32253.1    
 BHG40_12355   Aeromonas salmonicida subsp. masoucida RFAS1 ATD38638.1    
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