Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC 3.2.1.21); xylan 1,4-β-xylosidase (EC 3.2.1.37); β-glucosylceramidase (EC 3.2.1.45); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,3-β-glucosidase (EC 3.2.1.58); glucan 1,4-β-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin β-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (21009); Uniprot accession (2560); PDB accession (117); 3D entries (40); cryst (4)
All (20118) Archaea (104) Bacteria (18846) Eukaryota (1066) Viruses (1) unclassified (101) Structure (40 - 4 cryst) Characterized (300)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 189 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AM1_3082   Acaryochloris marina MBIC11017 ABW28078.1 B0CDK9  
 ASN_1325   Acetobacter senegalensis 108B CEF40690.1    
 ASN_1302   Acetobacter senegalensis 108B CEF40668.1    
 CIW82_05425   Acetobacter tropicalis BDGP1 ATJ90215.1    
 CIW82_05575   Acetobacter tropicalis BDGP1 ATJ90238.1    
 DOZ58_04815   Acetobacterium sp. KB-1 AWW26029.1    
 Awo_c16420   Acetobacterium woodii DSM 1030 AFA48424.1    
 BN85303960   Acholeplasma brassicae O502 CCV65417.1    
 BN85304700 (BglX)   Acholeplasma brassicae O502 CCV65491.1    
 BN85309520   Acholeplasma brassicae O502 CCV65973.1    
 BN85304390 (BglX)   Acholeplasma brassicae O502 CCV65460.1    
 BN85314460   Acholeplasma brassicae O502 CCV66467.1    
 NCTC10116_00722 (BglX)   Acholeplasma laidlawii NCTC10116 SQH56932.1    
 NCTC10116_00737 (BglB)   Acholeplasma laidlawii NCTC10116 SQH56947.1    
 NCTC10116_00282 (YbbD)   Acholeplasma laidlawii NCTC10116 SQH56505.1    
 ACL_0280   Acholeplasma laidlawii PG-8A ABX80904.1 A9NEX4  
 ACL_0715   Acholeplasma laidlawii PG-8A ABX81331.1 A9NG51  
 ACL_0730   Acholeplasma laidlawii PG-8A ABX81346.1 A9NG66  
 Aocu_07840   Acholeplasma oculi CDR30857.1    
 Aocu_07990 (BglX)   Acholeplasma oculi CDR30872.1    
 Aocu_11800 (NagZ)   Acholeplasma oculi CDR31253.1    
 BN85409310   Acholeplasma palmae J233 CCV64508.1    
 B9P52_21800   Achromobacter denitrificans PR1 ASC66745.1    
 APT56_21180   Achromobacter denitrificans USDA-ARS-USMARC-56712 ALX85503.1    
 CE205_10080   Achromobacter insolitus AB2 AXA70939.1    
 BUW96_11085   Achromobacter insolitus DSM 23807 APX75367.1    
 MC81_13370   Achromobacter insolitus FDAARGOS_88 AVG40303.1    
 AruCF_1373 (NagZ)   Achromobacter ruhlandii SCCH3:ACH 33-1365 AOU92264.1    
 C2U31_16220   Achromobacter sp. AONIH1 AUT47394.1    
 SAMN05428937_4044   Achromobacter sp. MFA1 R4 SIT28842.1    
 CVS48_23250   Achromobacter spanius DSM 23806 AUA58672.1    
 CLM73_18100   Achromobacter spanius MYb73 AVJ28871.1    
 AXYL_04378   Achromobacter xylosoxidans A8 ADP17697.1 E3HEX0  
 LH59_21195   Achromobacter xylosoxidans C54 AIR53154.1    
 AL504_26905   Achromobacter xylosoxidans FDAARGOS_147 AMG39326.1    
 AL509_05730   Achromobacter xylosoxidans FDAARGOS_150 AUZ18690.1    
 AL520_15505   Achromobacter xylosoxidans FDAARGOS_162 AMG45676.1    
 Axylo_1915   Achromobacter xylosoxidans MN001 AKP89417.1    
 AX27061_4603   Achromobacter xylosoxidans NBRC 15126 = ATCC 27061 AHC49060.1    
 ERS451415_04634 (NagZ)   Achromobacter xylosoxidans NCTC10807 CKH98543.1    
 NCTC10808_04574 (NagZ)   Achromobacter xylosoxidans NCTC10808 SQG76731.1    
 NH44784_063631   Achromobacter xylosoxidans NH44784-1996 CCH10298.1    
 CE206_23425   Achromobacter xylosoxidans SOLR10 AXA79184.1    
 Acfer_1474   Acidaminococcus fermentans DSM 20731 ADB47833.1 D2RL81  
 C4901_09420   Acidiferrobacter sp. SPIII_3 AWP23520.1    
 BW247_10275   Acidihalobacter ferrooxidans V8 APZ43427.1    
 BJI67_08315   Acidihalobacter prosperus V6 AOV17060.1    
 Acry_0568   Acidiphilium cryptum JF-5 ABQ29792.1 A5FW10  
 Acry_0951 (fragment)   Acidiphilium cryptum JF-5 ABQ30169.1 A5FX37  
 ACMV_06430   Acidiphilium multivorum AIU301 BAJ79990.1    
 ACMV_09360 (probable fragment)   Acidiphilium multivorum AIU301 BAJ80283.1    
 PACID_19970   Acidipropionibacterium acidipropionici ATCC 4875 AFV89792.1    
 PACID_31860   Acidipropionibacterium acidipropionici ATCC 4875 AFV90946.1    
 PACID_01920   Acidipropionibacterium acidipropionici ATCC 4875 AFV88042.1    
 PACID_13280   Acidipropionibacterium acidipropionici ATCC 4875 AFV89149.1    
 AXH35_08890   Acidipropionibacterium acidipropionici ATCC 55737 AMS05544.1    
 AXH35_16605   Acidipropionibacterium acidipropionici ATCC 55737 AMS06828.1    
 AXH35_02755   Acidipropionibacterium acidipropionici ATCC 55737 AMS04561.1    
 AXH35_01455   Acidipropionibacterium acidipropionici ATCC 55737 AMS04340.1    
 ASQ49_13175   Acidipropionibacterium acidipropionici CGMCC 1.2230 ALN16057.1    
 ASQ49_14555   Acidipropionibacterium acidipropionici CGMCC 1.2230 ALN16282.1    
 ASQ49_06245   Acidipropionibacterium acidipropionici CGMCC 1.2230 ALN14944.1    
 ASQ49_11920   Acidipropionibacterium acidipropionici CGMCC 1.2230 ALN15846.1    
 A8L58_01540   Acidipropionibacterium acidipropionici F3E8 AOZ45612.1    
 A8L58_02920   Acidipropionibacterium acidipropionici F3E8 AOZ45833.1    
 A8L58_04220   Acidipropionibacterium acidipropionici F3E8 AOZ48134.1    
 A8L58_10330   Acidipropionibacterium acidipropionici F3E8 AOZ47014.1    
 BWX38_00320   Acidipropionibacterium acidipropionici WSH1105 APZ07970.1    
 BWX38_02985   Acidipropionibacterium acidipropionici WSH1105 APZ08408.1    
 BWX38_01710   Acidipropionibacterium acidipropionici WSH1105 APZ10662.1    
 BWX38_08680   Acidipropionibacterium acidipropionici WSH1105 APZ09304.1    
 JS278_00339   Acidipropionibacterium sp. JS278 AXE37536.1    
 JS278_02000 (Nagz_2)   Acidipropionibacterium sp. JS278 AXE39154.1    
 JS278_01484 (BglB)   Acidipropionibacterium sp. JS278 AXE38651.1    
 JS278_01735 (Nagz_1)   Acidipropionibacterium sp. JS278 AXE38898.1    
 Acaty_c0269   Acidithiobacillus caldus ATCC 51756 AIA54160.1    
 A5904_00765   Acidithiobacillus caldus MTH-04 AUW33902.1    
 Atc_0242   Acidithiobacillus caldus SM-1 AEK56893.1    
 AFERRID_07770   Acidithiobacillus ferridurans JCM 18981 BBF64559.1    
 AFERRI_50234 (NagZ)   Acidithiobacillus ferrivorans SMH67033.1    
 Acife_0325   Acidithiobacillus ferrivorans SS3 AEM46554.1    
 AFE_2825 (NagZ)   Acidithiobacillus ferrooxidans ATCC 23270 ACK78082.1 B7J918  
 Lferr_2447   Acidithiobacillus ferrooxidans ATCC 53993 ACH84642.1 B5EPA1  
 LuPra_04207   Acidobacteria bacterium DSM 100886 AMY10963.1    
 LuPra_01061 (BglX)   Acidobacteria bacterium DSM 100886 AMY07878.1    
 ABI59_19215   Acidobacteria bacterium Mor1 ANM32364.1    
 ACPOL_1262   Acidobacteriaceae bacterium SBC82 AXC10610.1    
 ACPOL_5806   Acidobacteriaceae bacterium SBC82 AXC15052.1    
 ACPOL_0347   Acidobacteriaceae bacterium SBC82 AXC09728.1    
 ACPOL_1722   Acidobacteriaceae bacterium SBC82 AXC11064.1    
 ACPOL_4613   Acidobacteriaceae bacterium SBC82 AXC13885.1    
 ACPOL_0985   Acidobacteriaceae bacterium SBC82 AXC10336.1    
 ACPOL_2136   Acidobacteriaceae bacterium SBC82 AXC11460.1    
 ACPOL_4027   Acidobacteriaceae bacterium SBC82 AXC13306.1    
 ACPOL_2003   Acidobacteriaceae bacterium SBC82 AXC11339.1    
 ACP_2412 (Bxlb2)   Acidobacterium capsulatum ATCC 51196 ACO31611.1 C1F1A8  
 ACP_2415 (BxlB)   Acidobacterium capsulatum ATCC 51196 ACO32886.1 C1F1B0  
 ACP_1071 (Bxlb1)   Acidobacterium capsulatum ATCC 51196 ACO33323.1 C1F444  
 ACP_0717   Acidobacterium capsulatum ATCC 51196 ACO31306.1 C1F257  
 ACP_2957 (Cbg-1)   Acidobacterium capsulatum ATCC 51196 ACO32765.1 C1F4B5  
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