Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC; xylan 1,4-β-xylosidase (EC; β-glucosylceramidase (EC; β-N-acetylhexosaminidase (EC; α-L-arabinofuranosidase (EC; glucan 1,3-β-glucosidase (EC; glucan 1,4-β-glucosidase (EC; isoprimeverose-producing oligoxyloglucan hydrolase (EC; coniferin β-glucosidase (EC; exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (19964); Uniprot accession (2560); PDB accession (117); 3D entries (40); cryst (4)
All (19079) Archaea (102) Bacteria (17820) Eukaryota (1055) Viruses (1) unclassified (101) Structure (40 - 4 cryst) Characterized (300)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 179 |
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AM1_3082   Acaryochloris marina MBIC11017 ABW28078.1 B0CDK9  
 ASN_1325   Acetobacter senegalensis 108B CEF40690.1    
 ASN_1302   Acetobacter senegalensis 108B CEF40668.1    
 CIW82_05425   Acetobacter tropicalis BDGP1 ATJ90215.1    
 CIW82_05575   Acetobacter tropicalis BDGP1 ATJ90238.1    
 Awo_c16420   Acetobacterium woodii DSM 1030 AFA48424.1    
 BN85303960   Acholeplasma brassicae O502 CCV65417.1    
 BN85304700 (BglX)   Acholeplasma brassicae O502 CCV65491.1    
 BN85309520   Acholeplasma brassicae O502 CCV65973.1    
 BN85304390 (BglX)   Acholeplasma brassicae O502 CCV65460.1    
 BN85314460   Acholeplasma brassicae O502 CCV66467.1    
 ACL_0280   Acholeplasma laidlawii PG-8A ABX80904.1 A9NEX4  
 ACL_0715   Acholeplasma laidlawii PG-8A ABX81331.1 A9NG51  
 ACL_0730   Acholeplasma laidlawii PG-8A ABX81346.1 A9NG66  
 Aocu_07840   Acholeplasma oculi CDR30857.1    
 Aocu_07990 (BglX)   Acholeplasma oculi CDR30872.1    
 Aocu_11800 (NagZ)   Acholeplasma oculi CDR31253.1    
 BN85409310   Acholeplasma palmae J233 CCV64508.1    
 B9P52_21800   Achromobacter denitrificans PR1 ASC66745.1    
 APT56_21180   Achromobacter denitrificans USDA-ARS-USMARC-56712 ALX85503.1    
 BUW96_11085   Achromobacter insolitus DSM 23807 APX75367.1    
 MC81_13370   Achromobacter insolitus FDAARGOS_88 AVG40303.1    
 AruCF_1373 (NagZ)   Achromobacter ruhlandii SCCH3:ACH 33-1365 AOU92264.1    
 C2U31_16220   Achromobacter sp. AONIH1 AUT47394.1    
 SAMN05428937_4044   Achromobacter sp. MFA1 R4 SIT28842.1    
 CVS48_23250   Achromobacter spanius DSM 23806 AUA58672.1    
 CLM73_18100   Achromobacter spanius MYb73 AVJ28871.1    
 AXYL_04378   Achromobacter xylosoxidans A8 ADP17697.1 E3HEX0  
 LH59_21195   Achromobacter xylosoxidans C54 AIR53154.1    
 AL504_26905   Achromobacter xylosoxidans FDAARGOS_147 AMG39326.1    
 AL509_05730   Achromobacter xylosoxidans FDAARGOS_150 AUZ18690.1    
 AL520_15505   Achromobacter xylosoxidans FDAARGOS_162 AMG45676.1    
 Axylo_1915   Achromobacter xylosoxidans MN001 AKP89417.1    
 AX27061_4603   Achromobacter xylosoxidans NBRC 15126 = ATCC 27061 AHC49060.1    
 ERS451415_04634 (NagZ)   Achromobacter xylosoxidans NCTC10807 CKH98543.1    
 NH44784_063631   Achromobacter xylosoxidans NH44784-1996 CCH10298.1    
 Acfer_1474   Acidaminococcus fermentans DSM 20731 ADB47833.1 D2RL81  
 BW247_10275   Acidihalobacter ferrooxidans V8 APZ43427.1    
 BJI67_08315   Acidihalobacter prosperus V6 AOV17060.1    
 Acry_0568   Acidiphilium cryptum JF-5 ABQ29792.1 A5FW10  
 Acry_0951 (fragment)   Acidiphilium cryptum JF-5 ABQ30169.1 A5FX37  
 ACMV_06430   Acidiphilium multivorum AIU301 BAJ79990.1    
 ACMV_09360 (probable fragment)   Acidiphilium multivorum AIU301 BAJ80283.1    
 PACID_19970   Acidipropionibacterium acidipropionici ATCC 4875 AFV89792.1    
 PACID_31860   Acidipropionibacterium acidipropionici ATCC 4875 AFV90946.1    
 PACID_01920   Acidipropionibacterium acidipropionici ATCC 4875 AFV88042.1    
 PACID_13280   Acidipropionibacterium acidipropionici ATCC 4875 AFV89149.1    
 AXH35_08890   Acidipropionibacterium acidipropionici ATCC 55737 AMS05544.1    
 AXH35_16605   Acidipropionibacterium acidipropionici ATCC 55737 AMS06828.1    
 AXH35_02755   Acidipropionibacterium acidipropionici ATCC 55737 AMS04561.1    
 AXH35_01455   Acidipropionibacterium acidipropionici ATCC 55737 AMS04340.1    
 ASQ49_13175   Acidipropionibacterium acidipropionici CGMCC 1.2230 ALN16057.1    
 ASQ49_14555   Acidipropionibacterium acidipropionici CGMCC 1.2230 ALN16282.1    
 ASQ49_06245   Acidipropionibacterium acidipropionici CGMCC 1.2230 ALN14944.1    
 ASQ49_11920   Acidipropionibacterium acidipropionici CGMCC 1.2230 ALN15846.1    
 A8L58_01540   Acidipropionibacterium acidipropionici F3E8 AOZ45612.1    
 A8L58_02920   Acidipropionibacterium acidipropionici F3E8 AOZ45833.1    
 A8L58_04220   Acidipropionibacterium acidipropionici F3E8 AOZ48134.1    
 A8L58_10330   Acidipropionibacterium acidipropionici F3E8 AOZ47014.1    
 BWX38_00320   Acidipropionibacterium acidipropionici WSH1105 APZ07970.1    
 BWX38_02985   Acidipropionibacterium acidipropionici WSH1105 APZ08408.1    
 BWX38_01710   Acidipropionibacterium acidipropionici WSH1105 APZ10662.1    
 BWX38_08680   Acidipropionibacterium acidipropionici WSH1105 APZ09304.1    
 Acaty_c0269   Acidithiobacillus caldus ATCC 51756 AIA54160.1    
 A5904_00765   Acidithiobacillus caldus MTH-04 AUW33902.1    
 Atc_0242   Acidithiobacillus caldus SM-1 AEK56893.1    
 AFERRI_50234 (NagZ)   Acidithiobacillus ferrivorans SMH67033.1    
 Acife_0325   Acidithiobacillus ferrivorans SS3 AEM46554.1    
 AFE_2825 (NagZ)   Acidithiobacillus ferrooxidans ATCC 23270 ACK78082.1 B7J918  
 Lferr_2447   Acidithiobacillus ferrooxidans ATCC 53993 ACH84642.1 B5EPA1  
 LuPra_04207   Acidobacteria bacterium DSM 100886 AMY10963.1    
 LuPra_01061 (BglX)   Acidobacteria bacterium DSM 100886 AMY07878.1    
 ABI59_19215   Acidobacteria bacterium Mor1 ANM32364.1    
 ACP_2412 (Bxlb2)   Acidobacterium capsulatum ATCC 51196 ACO31611.1 C1F1A8  
 ACP_2415 (BxlB)   Acidobacterium capsulatum ATCC 51196 ACO32886.1 C1F1B0  
 ACP_1071 (Bxlb1)   Acidobacterium capsulatum ATCC 51196 ACO33323.1 C1F444  
 ACP_0717   Acidobacterium capsulatum ATCC 51196 ACO31306.1 C1F257  
 ACP_2957 (Cbg-1)   Acidobacterium capsulatum ATCC 51196 ACO32765.1 C1F4B5  
 ACP_0020   Acidobacterium capsulatum ATCC 51196 ACO33506.1 C1F7X7  
 ACP_2108   Acidobacterium capsulatum ATCC 51196 ACO33751.1 C1F943  
 Acel_0128   Acidothermus cellulolyticus 11B ABK51903.1 A0LR43  
 Acel_1659   Acidothermus cellulolyticus 11B ABK53431.1 A0LVH1  
 Acel_2050   Acidothermus cellulolyticus 11B ABK53822.1 A0LWL2  
 C8241_05765   Acidovorax avenae subsp. avenae AA78_5 AVS61289.1    
 C8247_04980   Acidovorax avenae subsp. avenae AA99_2 AVS69863.1    
 Acav_1215   Acidovorax avenae subsp. avenae ATCC 19860 ADX45137.1    
 C8234_03665   Acidovorax avenae subsp. avenae COLB1 AVS77259.1    
 C8237_04790   Acidovorax avenae subsp. avenae INDB2 AVS80477.1    
 C8239_05150   Acidovorax avenae subsp. avenae INV AVS84232.1    
 C8238_05075   Acidovorax avenae subsp. avenae KL3 AVS87700.1    
 C8246_08970   Acidovorax avenae subsp. avenae MD5 AVS91884.1    
 C8232_02395   Acidovorax avenae subsp. avenae MDB1 AVS95242.1    
 C8236_05545   Acidovorax avenae subsp. avenae MOR AVS98352.1    
 C8243_04920   Acidovorax avenae subsp. avenae NCT3 AVT01912.1    
 C8248_04805   Acidovorax avenae subsp. avenae QH1 AVT05372.1    
 C8242_04375   Acidovorax avenae subsp. avenae QHB1 AVT08818.1    
 C8235_04290   Acidovorax avenae subsp. avenae Sa2 AVT12184.1    
 C7Y68_05700   Acidovorax avenae subsp. avenae SH7 AVT19567.1    
 C8240_05165   Acidovorax cattleyae CAT98_1 AVS73523.1    
 Aave_1200   Acidovorax citrulli AAC00-1 ABM31792.1 A1TLF4  

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