Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC; xylan 1,4-β-xylosidase (EC; β-glucosylceramidase (EC; β-N-acetylhexosaminidase (EC; α-L-arabinofuranosidase (EC; glucan 1,3-β-glucosidase (EC; glucan 1,4-β-glucosidase (EC; isoprimeverose-producing oligoxyloglucan hydrolase (EC; coniferin β-glucosidase (EC; exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that some enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (26572); Uniprot accession (2560); PDB accession (127); 3D entries (45); cryst (4)
All (25632) Archaea (113) Bacteria (24192) Eukaryota (1224) Viruses (1) unclassified (102) Structure (45 - 4 cryst) Characterized (309)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 242 |
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AM1_3082   Acaryochloris marina MBIC11017 ABW28078.1 B0CDK9  
 ASN_1325   Acetobacter senegalensis 108B CEF40690.1    
 ASN_1302   Acetobacter senegalensis 108B CEF40668.1    
 CIW82_05425   Acetobacter tropicalis BDGP1 ATJ90215.1    
 CIW82_05575   Acetobacter tropicalis BDGP1 ATJ90238.1    
 DOZ58_04815   Acetobacterium sp. KB-1 AWW26029.1    
 Awo_c16420   Acetobacterium woodii DSM 1030 AFA48424.1    
 NCTC10138_00594 (Bglb_4)   Acholeplasma axanthum NCTC10138 VEU80235.1    
 NCTC10138_01603 (BglX)   Acholeplasma axanthum NCTC10138 VEU81205.1    
 NCTC10138_01512 (Bglb_5)   Acholeplasma axanthum NCTC10138 VEU81120.1    
 NCTC10138_00202 (Bglb_1)   Acholeplasma axanthum NCTC10138 VEU79849.1    
 NCTC10138_00591 (Bglb_3)   Acholeplasma axanthum NCTC10138 VEU80232.1    
 NCTC10138_00181 (Ybbd_1)   Acholeplasma axanthum NCTC10138 VEU79828.1    
 NCTC10138_00675 (Ybbd_2)   Acholeplasma axanthum NCTC10138 VEU80306.1    
 NCTC10138_00589 (Bglb_2)   Acholeplasma axanthum NCTC10138 VEU80230.1    
 BN85303960   Acholeplasma brassicae O502 CCV65417.1    
 BN85304700 (BglX)   Acholeplasma brassicae O502 CCV65491.1    
 BN85309520   Acholeplasma brassicae O502 CCV65973.1    
 BN85304390 (BglX)   Acholeplasma brassicae O502 CCV65460.1    
 BN85314460   Acholeplasma brassicae O502 CCV66467.1    
 NCTC10172_00453 (BglB)   Acholeplasma hippikon NCTC10172 VEU82442.1    
 NCTC10172_00827 (Ybbd_2)   Acholeplasma hippikon NCTC10172 VEU82803.1    
 NCTC10172_00119 (Ybbd_1)   Acholeplasma hippikon NCTC10172 VEU82113.1    
 NCTC10116_00722 (BglX)   Acholeplasma laidlawii NCTC10116 SQH56932.1    
 NCTC10116_00737 (BglB)   Acholeplasma laidlawii NCTC10116 SQH56947.1    
 NCTC10116_00282 (YbbD)   Acholeplasma laidlawii NCTC10116 SQH56505.1    
 ACL_0280   Acholeplasma laidlawii PG-8A ABX80904.1 A9NEX4  
 ACL_0715   Acholeplasma laidlawii PG-8A ABX81331.1 A9NG51  
 ACL_0730   Acholeplasma laidlawii PG-8A ABX81346.1 A9NG66  
 Aocu_07840   Acholeplasma oculi CDR30857.1    
 Aocu_07990 (BglX)   Acholeplasma oculi CDR30872.1    
 Aocu_11800 (NagZ)   Acholeplasma oculi CDR31253.1    
 BN85409310   Acholeplasma palmae J233 CCV64508.1    
 EC609_22520 (NagZ)   Achromobacter denitrificans PheN1 QCS64993.1    
 B9P52_21800   Achromobacter denitrificans PR1 ASC66745.1    
 APT56_21180   Achromobacter denitrificans USDA-ARS-USMARC-56712 ALX85503.1    
 CE205_10080   Achromobacter insolitus AB2 AXA70939.1    
 BUW96_11085   Achromobacter insolitus DSM 23807 APX75367.1    
 MC81_13370   Achromobacter insolitus FDAARGOS_88 AVG40303.1    
 NCTC13520_01993 (NagZ)   Achromobacter insolitus NCTC13520 VEG67434.1    
 AruCF_1373 (NagZ)   Achromobacter ruhlandii SCCH3:ACH 33-1365 AOU92264.1    
 C2U31_16220   Achromobacter sp. AONIH1 AUT47394.1    
 DVB37_17635   Achromobacter sp. B7 AYD65546.1    
 SAMN05428937_4044   Achromobacter sp. MFA1 R4 SIT28842.1    
 CVS48_23250   Achromobacter spanius DSM 23806 AUA58672.1    
 CLM73_18100   Achromobacter spanius MYb73 AVJ28871.1    
 NCTC13519_04700 (NagZ)   Achromobacter spanius NCTC13519 VEE59191.1    
 ELS24_19680   Achromobacter spanius UQ283 AZS80482.1    
 AXYL_04378   Achromobacter xylosoxidans A8 ADP17697.1 E3HEX0  
 LH59_21195   Achromobacter xylosoxidans C54 AIR53154.1    
 AL504_26905   Achromobacter xylosoxidans FDAARGOS_147 AMG39326.1    
 AL509_05730   Achromobacter xylosoxidans FDAARGOS_150 AUZ18690.1    
 AL520_15505   Achromobacter xylosoxidans FDAARGOS_162 AMG45676.1    
 Axylo_1915   Achromobacter xylosoxidans MN001 AKP89417.1    
 AX27061_4603   Achromobacter xylosoxidans NBRC 15126 = ATCC 27061 AHC49060.1    
 ERS451415_04634 (NagZ)   Achromobacter xylosoxidans NCTC10807 CKH98543.1    
 NCTC10808_04574 (NagZ)   Achromobacter xylosoxidans NCTC10808 SQG76731.1    
 NH44784_063631   Achromobacter xylosoxidans NH44784-1996 CCH10298.1    
 CE206_23425   Achromobacter xylosoxidans SOLR10 AXA79184.1    
 Acfer_1474   Acidaminococcus fermentans DSM 20731 ADB47833.1 D2RL81  
 C4901_09420   Acidiferrobacter sp. SPIII_3 AWP23520.1    
 BW247_10275   Acidihalobacter ferrooxidans V8 APZ43427.1    
 BJI67_08315   Acidihalobacter prosperus V6 AOV17060.1    
 Acry_0568   Acidiphilium cryptum JF-5 ABQ29792.1 A5FW10  
 Acry_0951 (fragment)   Acidiphilium cryptum JF-5 ABQ30169.1 A5FX37  
 ACMV_06430   Acidiphilium multivorum AIU301 BAJ79990.1    
 ACMV_09360 (probable fragment)   Acidiphilium multivorum AIU301 BAJ80283.1    
 PACID_19970   Acidipropionibacterium acidipropionici ATCC 4875 AFV89792.1    
 PACID_31860   Acidipropionibacterium acidipropionici ATCC 4875 AFV90946.1    
 PACID_01920   Acidipropionibacterium acidipropionici ATCC 4875 AFV88042.1    
 PACID_13280   Acidipropionibacterium acidipropionici ATCC 4875 AFV89149.1    
 AXH35_08890   Acidipropionibacterium acidipropionici ATCC 55737 AMS05544.1    
 AXH35_16605   Acidipropionibacterium acidipropionici ATCC 55737 AMS06828.1    
 AXH35_02755   Acidipropionibacterium acidipropionici ATCC 55737 AMS04561.1    
 AXH35_01455   Acidipropionibacterium acidipropionici ATCC 55737 AMS04340.1    
 ASQ49_13175   Acidipropionibacterium acidipropionici CGMCC 1.2230 ALN16057.1    
 ASQ49_14555   Acidipropionibacterium acidipropionici CGMCC 1.2230 ALN16282.1    
 ASQ49_06245   Acidipropionibacterium acidipropionici CGMCC 1.2230 ALN14944.1    
 ASQ49_11920   Acidipropionibacterium acidipropionici CGMCC 1.2230 ALN15846.1    
 A8L58_01540   Acidipropionibacterium acidipropionici F3E8 AOZ45612.1    
 A8L58_02920   Acidipropionibacterium acidipropionici F3E8 AOZ45833.1    
 A8L58_04220   Acidipropionibacterium acidipropionici F3E8 AOZ48134.1    
 A8L58_10330   Acidipropionibacterium acidipropionici F3E8 AOZ47014.1    
 FEZ30_07210   Acidipropionibacterium acidipropionici FAM 19036 QCV95088.1    
 FEZ30_00310   Acidipropionibacterium acidipropionici FAM 19036 QCV93921.1    
 FEZ30_05955   Acidipropionibacterium acidipropionici FAM 19036 QCV94867.1    
 FEZ30_08665   Acidipropionibacterium acidipropionici FAM 19036 QCV95324.1    
 DUY81_11755   Acidipropionibacterium acidipropionici WGS7 AZP38378.1    
 DUY81_02855   Acidipropionibacterium acidipropionici WGS7 AZP36891.1    
 DUY81_10340   Acidipropionibacterium acidipropionici WGS7 AZP38150.1    
 DUY81_09030   Acidipropionibacterium acidipropionici WGS7 AZP37922.1    
 BWX38_00320   Acidipropionibacterium acidipropionici WSH1105 APZ07970.1    
 BWX38_02985   Acidipropionibacterium acidipropionici WSH1105 APZ08408.1    
 BWX38_01710   Acidipropionibacterium acidipropionici WSH1105 APZ10662.1    
 BWX38_08680   Acidipropionibacterium acidipropionici WSH1105 APZ09304.1    
 FEZ32_10590   Acidipropionibacterium jensenii FAM 19038 QCV88735.1    
 FEZ32_13295   Acidipropionibacterium jensenii FAM 19038 QCV89184.1    
 FEZ32_11065   Acidipropionibacterium jensenii FAM 19038 QCV88815.1    
 C0Z11_07790   Acidipropionibacterium jensenii JS279 AZZ42204.1    
 C0Z11_05680   Acidipropionibacterium jensenii JS279 AZZ41850.1    

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