Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC 3.2.1.21); xylan 1,4-β-xylosidase (EC 3.2.1.37); β-glucosylceramidase (EC 3.2.1.45); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,3-β-glucosidase (EC 3.2.1.58); glucan 1,4-β-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin β-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (17231); Uniprot accession (2560); PDB accession (105); 3D entries (33); cryst (4)
All (16380) Archaea (94) Bacteria (15236) Eukaryota (949) Viruses (1) unclassified (100) Structure (33 - 4 cryst) Characterized (293)
| 1 | ... | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ... | 153 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AMETH_6610 (NagA)   Amycolatopsis methanolica 239 AIJ26702.1    
 AMETH_2236 (BglX) (fragment)   Amycolatopsis methanolica 239 AIJ22328.1    
 SD37_02670   Amycolatopsis orientalis B-37 ANN14664.1    
 SD37_05955   Amycolatopsis orientalis B-37 ANN15242.1    
 SD37_20795   Amycolatopsis orientalis B-37 ANN17846.1    
 SD37_36580   Amycolatopsis orientalis B-37 ANN20566.1    
 SD37_23495   Amycolatopsis orientalis B-37 ANN18309.1    
 SD37_34545   Amycolatopsis orientalis B-37 ANN20212.1    
 SD37_24025   Amycolatopsis orientalis B-37 ANN18396.1    
 SD37_23490   Amycolatopsis orientalis B-37 ANN18308.1    
 AORI_0933   Amycolatopsis orientalis HCCB10007 AGM03522.1    
 AORI_1329 (NagZ)   Amycolatopsis orientalis HCCB10007 AGM03918.1    
 AORI_4858   Amycolatopsis orientalis HCCB10007 AGM07442.1    
 AORI_6949 (NagZ)   Amycolatopsis orientalis HCCB10007 AGM09531.1    
 AORI_7586 (NagZ)   Amycolatopsis orientalis HCCB10007 AGM10168.1    
 Anacy_3876   Anabaena cylindrica PCC 7122 AFZ59251.1    
 chitosanase (ChoA) (fragment)   Anabaena iyengarii RPAN9 ACM91579.1 C0KRU8  
 chitosanase (ChoA) (fragment)   Anabaena laxa RPAN8 / CCC 381 ACM91578.1 C0KRU7  
 ANA_C20302   Anabaena sp. 90 AFW96749.1    
 AA650_04085   Anabaena sp. wa102 ALB39750.1    
 Cho   Anabaena sphaerica RPAN12 ACY66645.1 D1MAD8  
 NIES21_26160   Anabaenopsis circularis NIES-21 BAY16782.1    
 Apre_1591   Anaerococcus prevotii DSM 20548 ACV29612.1 C7REJ9  
 ANT_18720   Anaerolinea thermophila UNI-1 BAJ63898.1    
 ANT_13340   Anaerolinea thermophila UNI-1 BAJ63366.1    
 ANT_17560   Anaerolinea thermophila UNI-1 BAJ63782.1    
 ANT_24960   Anaerolinea thermophila UNI-1 BAJ64522.1    
 BEQ56_07990   Anaerolineaceae bacterium oral taxon 439 W11661 AOH43419.1    
 BEQ56_04065   Anaerolineaceae bacterium oral taxon 439 W11661 AOH42722.1    
 A2cp1_4420   Anaeromyxobacter dehalogenans 2CP-1 ACL67737.1 B8JCL7  
 Adeh_4264   Anaeromyxobacter dehalogenans 2CP-C ABC84028.1 Q2IHH1  
 Anae109_4419   Anaeromyxobacter sp. Fw109-5 ABS28597.1 A7HIQ1  
 Anae109_4074   Anaeromyxobacter sp. Fw109-5 ABS28252.1 A7HHQ6  
 Anae109_3267   Anaeromyxobacter sp. Fw109-5 ABS27460.1 A7HFG4  
 AnaeK_4399   Anaeromyxobacter sp. K ACG75602.1 B4UJM1  
 DO83_10555   Anaerostipes hadrus BPB5 AQP39976.1    
 CPRO_04360 (NagZ)   Anaerotignum propionicum DSM 1682 X2 AMJ40045.1    
 ANTHELSMS3_03587 (NagZ)   Antarctobacter heliothermus SMS3 ASP22210.1    
 BXU06_05690   Aquaspirillum sp. LM1 AQR64606.1    
 SAMN00777080_4614   Aquiflexum balticum DSM 16537 SMD45941.1    
 SAMN00777080_0266   Aquiflexum balticum DSM 16537 SMD41736.1    
 A9P82_05475   Arachidicoccus sp. BS20 ANI88786.1    
 A9P82_14665   Arachidicoccus sp. BS20 ANI90418.1    
 A9P82_12190   Arachidicoccus sp. BS20 ANI89978.1    
 A9P82_13770   Arachidicoccus sp. BS20 ANI90266.1    
 A9P82_02165   Arachidicoccus sp. BS20 ANI88217.1    
 A9P82_13180   Arachidicoccus sp. BS20 ANI90153.1    
 A9P82_12150   Arachidicoccus sp. BS20 ANI90765.1    
 A9P82_07975   Arachidicoccus sp. BS20 ANI89233.1    
 AA314_00014   Archangium gephyra DSM 2261 AKI98387.1    
 AA314_10118 (fragment)   Archangium gephyra DSM 2261 AKJ08492.1    
 AA314_03477   Archangium gephyra DSM 2261 AKJ01851.1    
 AA314_02241   Archangium gephyra DSM 2261 AKJ00615.1    
 AA314_08720   Archangium gephyra DSM 2261 AKJ07094.1    
 AA314_02838   Archangium gephyra DSM 2261 AKJ01212.1    
 AA314_09292   Archangium gephyra DSM 2261 AKJ07666.1    
 A7H1H_1036   Arcobacter butzleri 7h1h AGR77337.1    
 ABED_0981   Arcobacter butzleri ED-1 BAK70698.1    
 SAMEA4475700_01045   Arcobacter butzleri NCTC 12481 SNV27784.1    
 Abu_1035   Arcobacter butzleri RM4018 ABV67295.1 A8ETM1  
 ABLL_1750   Arcobacter sp. L BAK73625.1    
 LPB137_04795   Arcobacter sp. LPB0137 APW65207.1    
 CFX0092_b0832   Ardenticatena Cfx-K CUS06366.1    
 CFX0092_a2966   Ardenticatena Cfx-K CUS04844.1
CUS04862.2
   
 CFX0092_a0467   Ardenticatena Cfx-K CUS02348.1
CUS02359.2
   
 CFX0092_a1634 (BglB)   Ardenticatena Cfx-K CUS03512.1
CUS03526.2
   
 CFX0092_a1005 (BglX)   Ardenticatena Cfx-K CUS02883.1
CUS02893.2
   
 AREALGSMS7_03216   Arenibacter algicola SMS7 ASO06643.1    
 AREALGSMS7_02550   Arenibacter algicola SMS7 ASO05993.1    
 AREALGSMS7_03401   Arenibacter algicola SMS7 ASO06826.1    
 AREALGSMS7_01333 (BglB)   Arenibacter algicola SMS7 ASO04806.1    
 ebA5547 (NagZ)   Aromatoleum aromaticum EbN1 CAI09283.1 Q5P081  
 ADJ73_10560   Arsenicicoccus sp. oral taxon 190 F0371 AKT51629.1    
 ARN_29200 (NagZ)   Arsenophonus nasoniae CBA75455.1 D2U2U1  
 ARN_13140   Arsenophonus nasoniae CBA72620.1 D2TYT2  
 AS189_07555   Arthrobacter alpinus ERGS4:06 ALO66371.1    
 AS189_17220   Arthrobacter alpinus ERGS4:06 ALO67901.1    
 AS189_04165   Arthrobacter alpinus ERGS4:06 ALO65835.1    
 AS189_18505   Arthrobacter alpinus ERGS4:06 ALO68123.1    
 AS189_07330   Arthrobacter alpinus ERGS4:06 ALO68403.1    
 AOC05_10575   Arthrobacter alpinus R3.8 ALE94161.1    
 AOC05_00860   Arthrobacter alpinus R3.8 ALE91248.1    
 AOC05_02140   Arthrobacter alpinus R3.8 ALE93904.1    
 BN1051_02968 (BglX)   Arthrobacter saudimassiliensis 11W110_air CEA09596.1    
 BN1051_00677   Arthrobacter saudimassiliensis 11W110_air CEA07365.1    
 CGQ24_17415   Arthrobacter sp. 7749 ASN40603.1    
 CGQ24_02775   Arthrobacter sp. 7749 ASN38041.1    
 MB46_00235   Arthrobacter sp. A3 ALV44171.1    
 MB46_11115   Arthrobacter sp. A3 ALV45953.1    
 MB46_01680   Arthrobacter sp. A3 ALV47324.1    
 MB46_11305   Arthrobacter sp. A3 ALV47602.1    
 MB46_14520   Arthrobacter sp. A3 ALV46525.1    
 AUT26_13535   Arthrobacter sp. ATCC 21022 AMB42567.1    
 AUT26_02875   Arthrobacter sp. ATCC 21022 AMB39281.1    
 AUT26_02500   Arthrobacter sp. ATCC 21022 AMB39214.1    
 AL755_15970   Arthrobacter sp. ERGS1:01 ALE07895.1    
 AL755_02405   Arthrobacter sp. ERGS1:01 ALE04538.1    
 AL755_16835   Arthrobacter sp. ERGS1:01 ALE07930.1    
 AL755_21640   Arthrobacter sp. ERGS1:01 ALE07477.1    
 AL755_05360   Arthrobacter sp. ERGS1:01 ALE07584.1    
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