Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC 3.2.1.21); xylan 1,4-β-xylosidase (EC 3.2.1.37); β-glucosylceramidase (EC 3.2.1.45); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,3-β-glucosidase (EC 3.2.1.58); glucan 1,4-β-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin β-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (17817); Uniprot accession (2560); PDB accession (106); 3D entries (34); cryst (4)
All (16969) Archaea (94) Bacteria (15784) Eukaryota (990) Viruses (1) unclassified (100) Structure (34 - 4 cryst) Characterized (295)
| 1 | ... | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ... | 158 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 RAM_44210   Amycolatopsis mediterranei S699 AEK47309.1
AFO82015.1
   
 RAM_22145   Amycolatopsis mediterranei S699 AEK42909.1
AFO77832.1
   
 RAM_41745   Amycolatopsis mediterranei S699 AEK46816.1
AFO81536.1
   
 RAM_20400   Amycolatopsis mediterranei S699 AEK42560.1
AFO77490.1
   
 RAM_45195   Amycolatopsis mediterranei S699 AEK47506.1
AFO82207.1
   
 RAM_04785   Amycolatopsis mediterranei S699 AEK39449.1
AFO74472.1
   
 AMES_1705 (BglX)   Amycolatopsis mediterranei S699 AFO75241.1
AEK40235.1
   
 AMES_5187 (BglX)   Amycolatopsis mediterranei S699 AFO78723.1
AEK43826.1
   
 AMED_0939   Amycolatopsis mediterranei U32 ADJ42758.1 D8I3K3  
 AMED_1295   Amycolatopsis mediterranei U32 ADJ43109.1 D8I6V9  
 AMED_1718 (BglX)   Amycolatopsis mediterranei U32 ADJ43529.1 D8HNH8  
 AMED_4002   Amycolatopsis mediterranei U32 ADJ45779.1 D8HPV7  
 AMED_4348   Amycolatopsis mediterranei U32 ADJ46121.1 D8HSD4  
 AMED_4507 (BglX)   Amycolatopsis mediterranei U32 ADJ46277.1 D8HTY3  
 AMED_5251 (BglX)   Amycolatopsis mediterranei U32 ADJ47013.1 D8I2Y8  
 AMED_7267   Amycolatopsis mediterranei U32 ADJ48983.1 D8I7W0  
 AMED_7379 (BglX)   Amycolatopsis mediterranei U32 ADJ49093.1 D8I9C6  
 AMED_7574   Amycolatopsis mediterranei U32 ADJ49287.1 D8HP73  
 AMED_8125   Amycolatopsis mediterranei U32 ADJ49828.1 D8HLX3  
 AMED_8808   Amycolatopsis mediterranei U32 ADJ50501.1 D8HK80  
 AMED_4365   Amycolatopsis mediterranei U32 ADJ46138.1 D8HSF1  
 AMED_8614   Amycolatopsis mediterranei U32 ADJ50309.1 D8HJN2  
 AMETH_0372   Amycolatopsis methanolica 239 AIJ20464.1    
 AMETH_3402 (CelD)   Amycolatopsis methanolica 239 AIJ23494.1    
 AMETH_6610 (NagA)   Amycolatopsis methanolica 239 AIJ26702.1    
 AMETH_2236 (BglX) (fragment)   Amycolatopsis methanolica 239 AIJ22328.1    
 SD37_02670   Amycolatopsis orientalis B-37 ANN14664.1    
 SD37_05955   Amycolatopsis orientalis B-37 ANN15242.1    
 SD37_20795   Amycolatopsis orientalis B-37 ANN17846.1    
 SD37_36580   Amycolatopsis orientalis B-37 ANN20566.1    
 SD37_23495   Amycolatopsis orientalis B-37 ANN18309.1    
 SD37_34545   Amycolatopsis orientalis B-37 ANN20212.1    
 SD37_24025   Amycolatopsis orientalis B-37 ANN18396.1    
 SD37_23490   Amycolatopsis orientalis B-37 ANN18308.1    
 AORI_0933   Amycolatopsis orientalis HCCB10007 AGM03522.1    
 AORI_1329 (NagZ)   Amycolatopsis orientalis HCCB10007 AGM03918.1    
 AORI_4858   Amycolatopsis orientalis HCCB10007 AGM07442.1    
 AORI_6949 (NagZ)   Amycolatopsis orientalis HCCB10007 AGM09531.1    
 AORI_7586 (NagZ)   Amycolatopsis orientalis HCCB10007 AGM10168.1    
 Anacy_3876   Anabaena cylindrica PCC 7122 AFZ59251.1    
 chitosanase (ChoA) (fragment)   Anabaena iyengarii RPAN9 ACM91579.1 C0KRU8  
 chitosanase (ChoA) (fragment)   Anabaena laxa RPAN8 / CCC 381 ACM91578.1 C0KRU7  
 ANA_C20302   Anabaena sp. 90 AFW96749.1    
 AA650_04085   Anabaena sp. wa102 ALB39750.1    
 Cho   Anabaena sphaerica RPAN12 ACY66645.1 D1MAD8  
 NIES21_26160   Anabaenopsis circularis NIES-21 BAY16782.1    
 Apre_1591   Anaerococcus prevotii DSM 20548 ACV29612.1 C7REJ9  
 ANT_18720   Anaerolinea thermophila UNI-1 BAJ63898.1    
 ANT_13340   Anaerolinea thermophila UNI-1 BAJ63366.1    
 ANT_17560   Anaerolinea thermophila UNI-1 BAJ63782.1    
 ANT_24960   Anaerolinea thermophila UNI-1 BAJ64522.1    
 BEQ56_07990   Anaerolineaceae bacterium oral taxon 439 W11661 AOH43419.1    
 BEQ56_04065   Anaerolineaceae bacterium oral taxon 439 W11661 AOH42722.1    
 A2cp1_4420   Anaeromyxobacter dehalogenans 2CP-1 ACL67737.1 B8JCL7  
 Adeh_4264   Anaeromyxobacter dehalogenans 2CP-C ABC84028.1 Q2IHH1  
 Anae109_4419   Anaeromyxobacter sp. Fw109-5 ABS28597.1 A7HIQ1  
 Anae109_4074   Anaeromyxobacter sp. Fw109-5 ABS28252.1 A7HHQ6  
 Anae109_3267   Anaeromyxobacter sp. Fw109-5 ABS27460.1 A7HFG4  
 AnaeK_4399   Anaeromyxobacter sp. K ACG75602.1 B4UJM1  
 DO83_10555   Anaerostipes hadrus BPB5 AQP39976.1    
 CPRO_04360 (NagZ)   Anaerotignum propionicum DSM 1682 X2 AMJ40045.1    
 ANTHELSMS3_03587 (NagZ)   Antarctobacter heliothermus SMS3 ASP22210.1    
 BXU06_05690   Aquaspirillum sp. LM1 AQR64606.1    
 SAMN00777080_4614   Aquiflexum balticum DSM 16537 SMD45941.1    
 SAMN00777080_0266   Aquiflexum balticum DSM 16537 SMD41736.1    
 A9P82_05475   Arachidicoccus sp. BS20 ANI88786.1    
 A9P82_14665   Arachidicoccus sp. BS20 ANI90418.1    
 A9P82_12190   Arachidicoccus sp. BS20 ANI89978.1    
 A9P82_13770   Arachidicoccus sp. BS20 ANI90266.1    
 A9P82_02165   Arachidicoccus sp. BS20 ANI88217.1    
 A9P82_13180   Arachidicoccus sp. BS20 ANI90153.1    
 A9P82_12150   Arachidicoccus sp. BS20 ANI90765.1    
 A9P82_07975   Arachidicoccus sp. BS20 ANI89233.1    
 AA314_00014   Archangium gephyra DSM 2261 AKI98387.1    
 AA314_10118 (fragment)   Archangium gephyra DSM 2261 AKJ08492.1    
 AA314_03477   Archangium gephyra DSM 2261 AKJ01851.1    
 AA314_02241   Archangium gephyra DSM 2261 AKJ00615.1    
 AA314_08720   Archangium gephyra DSM 2261 AKJ07094.1    
 AA314_02838   Archangium gephyra DSM 2261 AKJ01212.1    
 AA314_09292   Archangium gephyra DSM 2261 AKJ07666.1    
 A7H1H_1036   Arcobacter butzleri 7h1h AGR77337.1    
 ABED_0981   Arcobacter butzleri ED-1 BAK70698.1    
 SAMEA4475700_01045   Arcobacter butzleri NCTC 12481 SNV27784.1    
 Abu_1035   Arcobacter butzleri RM4018 ABV67295.1 A8ETM1  
 ABLL_1750   Arcobacter sp. L BAK73625.1    
 LPB137_04795   Arcobacter sp. LPB0137 APW65207.1    
 CFX0092_b0832   Ardenticatena Cfx-K CUS06366.1    
 CFX0092_a2966   Ardenticatena Cfx-K CUS04844.1
CUS04862.2
   
 CFX0092_a0467   Ardenticatena Cfx-K CUS02348.1
CUS02359.2
   
 CFX0092_a1634 (BglB)   Ardenticatena Cfx-K CUS03512.1
CUS03526.2
   
 CFX0092_a1005 (BglX)   Ardenticatena Cfx-K CUS02883.1
CUS02893.2
   
 AREALGSMS7_03216   Arenibacter algicola SMS7 ASO06643.1    
 AREALGSMS7_02550   Arenibacter algicola SMS7 ASO05993.1    
 AREALGSMS7_03401   Arenibacter algicola SMS7 ASO06826.1    
 AREALGSMS7_01333 (BglB)   Arenibacter algicola SMS7 ASO04806.1    
 ebA5547 (NagZ)   Aromatoleum aromaticum EbN1 CAI09283.1 Q5P081  
 ADJ73_10560   Arsenicicoccus sp. oral taxon 190 F0371 AKT51629.1    
 ARN_29200 (NagZ)   Arsenophonus nasoniae CBA75455.1 D2U2U1  
 ARN_13140   Arsenophonus nasoniae CBA72620.1 D2TYT2  
 AS189_07555   Arthrobacter alpinus ERGS4:06 ALO66371.1    
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