Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC; xylan 1,4-β-xylosidase (EC; β-glucosylceramidase (EC; β-N-acetylhexosaminidase (EC; α-L-arabinofuranosidase (EC; glucan 1,3-β-glucosidase (EC; glucan 1,4-β-glucosidase (EC; isoprimeverose-producing oligoxyloglucan hydrolase (EC; coniferin β-glucosidase (EC; exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (20155); Uniprot accession (2560); PDB accession (117); 3D entries (40); cryst (4)
All (19268) Archaea (102) Bacteria (18008) Eukaryota (1056) Viruses (1) unclassified (101) Structure (40 - 4 cryst) Characterized (300)
| 1 | ... | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ... | 181 |
Protein Name EC#OrganismGenBank UniprotPDB/3D
 I634_07980   Alteromonas mediterranea U8 AGP93314.1    
 I636_02715   Alteromonas mediterranea UM4b AGQ00419.1    
 I636_18125   Alteromonas mediterranea UM4b AGQ03447.1    
 I636_18930   Alteromonas mediterranea UM4b AGQ03605.1    
 I636_08420   Alteromonas mediterranea UM4b AGQ01538.1    
 I635_18970   Alteromonas mediterranea UM7 AGP99287.1    
 I635_19780   Alteromonas mediterranea UM7 AGP99447.1    
 I635_02700   Alteromonas mediterranea UM7 AGP96085.1    
 I635_08330   Alteromonas mediterranea UM7 AGP97190.1    
 AV942_18690   Alteromonas mediterranea UM8 AMJ80172.1    
 AV942_02640   Alteromonas mediterranea UM8 AMJ77285.1    
 AV942_19475   Alteromonas mediterranea UM8 AMJ80308.1    
 AV942_08255   Alteromonas mediterranea UM8 AMJ80542.1    
 ambt_10425   Alteromonas naphthalenivorans AEF03609.1    
 ambt_15775   Alteromonas naphthalenivorans AEF04665.1    
 ambt_20070   Alteromonas naphthalenivorans AEF05505.1    
 AV939_02510   Alteromonas sp. Mac1 AMJ88697.1    
 AV939_18585   Alteromonas sp. Mac1 AMJ88403.1    
 AV939_04480   Alteromonas sp. Mac1 AMJ85903.1    
 AV939_07430   Alteromonas sp. Mac1 AMJ88784.1    
 AV940_02535   Alteromonas sp. Mac2 AMJ89443.1    
 AV940_18280   Alteromonas sp. Mac2 AMJ92257.1    
 AV940_07260   Alteromonas sp. Mac2 AMJ92637.1    
 AV940_04325   Alteromonas sp. Mac2 AMJ89760.1    
 CW735_18230   Alteromonas sp. MB-3u-76 AUC89884.1    
 CW735_02375 (fragment)   Alteromonas sp. MB-3u-76 AUC90127.1    
 CW735_12015   Alteromonas sp. MB-3u-76 AUC88819.1    
 BM527_02330   Alteromonas sp. Mex14 APD85021.1    
 BM527_17865   Alteromonas sp. Mex14 APD87812.1    
 BM527_07815   Alteromonas sp. Mex14 APD88137.1    
 BM528_16935   Alteromonas sp. RW2A1 APE07257.1    
 BM528_02565   Alteromonas sp. RW2A1 APE04790.1    
 BM528_06600   Alteromonas sp. RW2A1 APE05489.1    
 AOR13_1939   Alteromonas stellipolaris LMG 21856 ALM90969.1    
 AOR13_3017   Alteromonas stellipolaris LMG 21856 ALM92021.1    
 AOR13_3813   Alteromonas stellipolaris LMG 21856 ALM92806.1    
 AOR13_2665   Alteromonas stellipolaris LMG 21856 ALM91669.1    
 AVL57_03695   Alteromonas stellipolaris LMG 21861 AMJ76266.1    
 AVL57_08420   Alteromonas stellipolaris LMG 21861 AMJ76349.1    
 AVL57_19615   Alteromonas stellipolaris LMG 21861 AMJ75975.1    
 AVL57_05410   Alteromonas stellipolaris LMG 21861 AMJ73459.1    
 A6K25_02160   Alteromonas stellipolaris PQQ-42 ANB20193.1    
 A6K25_17080   Alteromonas stellipolaris PQQ-42 ANB23685.1    
 A6K25_00370   Alteromonas stellipolaris PQQ-42 ANB19880.1    
 A6K25_06030   Alteromonas stellipolaris PQQ-42 ANB20879.1    
 A6F57_14125   Alteromonas stellipolaris PQQ-44 ANB26224.1    
 A6F57_12430   Alteromonas stellipolaris PQQ-44 ANB25928.1    
 A6F57_17720   Alteromonas stellipolaris PQQ-44 ANB26855.1    
 A6F57_08535   Alteromonas stellipolaris PQQ-44 ANB25243.1    
 AA2016_0352   Aminobacter aminovorans KCTC 2477 AMS39292.1    
 AA2016_0161   Aminobacter aminovorans KCTC 2477 AMS39103.1    
 BglG204b   Aminobacter sp. Gsoil204 AGA60127.1    
 CO731_03755 (NagZ)   Aminobacter sp. MSH1 AWC24273.1    
 AXY_07670   Amphibacillus xylanus NBRC 15112 BAM46899.1    
 AXY_22780   Amphibacillus xylanus NBRC 15112 BAM48410.1    
 AXY_22860 (BglB)   Amphibacillus xylanus NBRC 15112 BAM48418.1    
 AXY_22880   Amphibacillus xylanus NBRC 15112 BAM48420.1    
 AJAP_32910   Amycolatopsis japonica MG417-CF17 AIG79396.1    
 AJAP_15280   Amycolatopsis japonica MG417-CF17 AIG75932.1    
 AJAP_39560   Amycolatopsis japonica MG417-CF17 AIG80692.1    
 AJAP_04360 (fragment)   Amycolatopsis japonica MG417-CF17 AIG73794.1    
 AJAP_34900   Amycolatopsis japonica MG417-CF17 AIG79787.1    
 SAMN04489733_7504   Amycolatopsis keratiniphila FH 1893 SDU64033.1    
 SAMN04489733_4580   Amycolatopsis keratiniphila FH 1893 SDU46216.1    
 SAMN04489733_6677   Amycolatopsis keratiniphila FH 1893 SDU59369.1    
 SAMN04489733_2481   Amycolatopsis keratiniphila FH 1893 SDU25865.1    
 SAMN04489733_4989   Amycolatopsis keratiniphila FH 1893 SDU49307.1    
 SAMN04489733_0935   Amycolatopsis keratiniphila FH 1893 SDU07690.1    
 SAMN04489733_2480   Amycolatopsis keratiniphila FH 1893 SDU25854.1    
 BB31_15885   Amycolatopsis lurida NRRL 2430 AJK54761.1    
 BB31_03175 (fragment)   Amycolatopsis lurida NRRL 2430 AJK52497.1    
 BB31_29270   Amycolatopsis lurida NRRL 2430 AJK57255.1    
 BB31_29275   Amycolatopsis lurida NRRL 2430 AJK57256.1    
 BB31_01795   Amycolatopsis lurida NRRL 2430 AJK52236.1    
 BB31_23570   Amycolatopsis lurida NRRL 2430 AJK56201.1    
 BB31_27770   Amycolatopsis lurida NRRL 2430 AJK56964.1    
 BB31_29760   Amycolatopsis lurida NRRL 2430 AJK57324.1    
 B737_5187 (BglX)   Amycolatopsis mediterranei RB AGT85851.1    
 B737_4313 (NagZ)   Amycolatopsis mediterranei RB AGT84977.1    
 B737_0937   Amycolatopsis mediterranei RB AGT81601.1    
 B737_8484   Amycolatopsis mediterranei RB AGT89144.1    
 B737_8676   Amycolatopsis mediterranei RB AGT89336.1    
 B737_1288   Amycolatopsis mediterranei RB AGT81952.1    
 B737_7157   Amycolatopsis mediterranei RB AGT87819.1    
 B737_1706 (BglX)   Amycolatopsis mediterranei RB AGT82370.1    
 B737_8004   Amycolatopsis mediterranei RB AGT88665.1    
 B737_4296   Amycolatopsis mediterranei RB AGT84960.1    
 B737_4452 (BglX)   Amycolatopsis mediterranei RB AGT85116.1    
 B737_7268 (BglX)   Amycolatopsis mediterranei RB AGT87929.1    
 B737_7462   Amycolatopsis mediterranei RB AGT88123.1    
 B737_3954   Amycolatopsis mediterranei RB AGT84618.1    
 RAM_22230   Amycolatopsis mediterranei S699 AEK42926.1
 RAM_06570   Amycolatopsis mediterranei S699 AEK39806.1
 RAM_22950   Amycolatopsis mediterranei S699 AEK43070.1
 RAM_38915   Amycolatopsis mediterranei S699 AEK46250.1
 RAM_37935   Amycolatopsis mediterranei S699 AEK46054.1
 RAM_37330   Amycolatopsis mediterranei S699 AEK45933.1
 RAM_44210   Amycolatopsis mediterranei S699 AEK47309.1
 RAM_22145   Amycolatopsis mediterranei S699 AEK42909.1
 RAM_41745   Amycolatopsis mediterranei S699 AEK46816.1

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