Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC 3.2.1.21); xylan 1,4-β-xylosidase (EC 3.2.1.37); β-glucosylceramidase (EC 3.2.1.45); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,3-β-glucosidase (EC 3.2.1.58); glucan 1,4-β-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin β-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (17817); Uniprot accession (2560); PDB accession (106); 3D entries (34); cryst (4)
All (16969) Archaea (94) Bacteria (15784) Eukaryota (990) Viruses (1) unclassified (100) Structure (34 - 4 cryst) Characterized (295)
| 1 | ... | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ... | 158 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AL1_13740   Alistipes shahii WAL 8301 CBK63828.1 D4ILL6  
 AL1_13780   Alistipes shahii WAL 8301 CBK63832.1 D4ILM0  
 AL1_15910   Alistipes shahii WAL 8301 CBK63996.1 D4IM34  
 AL1_11640   Alistipes shahii WAL 8301 CBK63660.1 D4IL48  
 AL1_13770   Alistipes shahii WAL 8301 CBK63831.1 D4ILL9  
 Mlg_1327   Alkalilimnicola ehrlichii MLHE-1 ABI56676.1 Q0A911  
 Amet_1301   Alkaliphilus metalliredigens QYMF ABR47506.1 A6TMT8  
 Clos_2373   Alkaliphilus oremlandii OhILAs ABW19905.1 A8MJC3  
 CDL62_00090   Alkalitalea saponilacus DSM 24412 ASB50990.1    
 CDL62_10005   Alkalitalea saponilacus DSM 24412 ASB49446.1    
 CDL62_05050   Alkalitalea saponilacus DSM 24412 ASB48548.1    
 CDL62_00100   Alkalitalea saponilacus DSM 24412 ASB47665.1    
 CDL62_11970   Alkalitalea saponilacus DSM 24412 ASB49798.1    
 CDL62_06305   Alkalitalea saponilacus DSM 24412 ASB48771.1    
 CDL62_10000   Alkalitalea saponilacus DSM 24412 ASB49445.1    
 ORF   Alloactinosynnema sp. L-07 CRK57453.1    
 ORF   Alloactinosynnema sp. L-07 CRK61072.1    
 ORF   Alloactinosynnema sp. L-07 CRK62215.1    
 Alvin_0490   Allochromatium vinosum DSM 180 ADC61447.1 D3RNT7  
 SD28_05140   Allofrancisella guangzhouensis 08HL01032 AJC49060.1    
 SAMN04489726_6997   Allokutzneria albata DSM 44149 SDN52292.1    
 SAMN04489726_7597   Allokutzneria albata DSM 44149 SDN65388.1    
 SAMN04489726_5736   Allokutzneria albata DSM 44149 SDN25405.1    
 SAMN04489726_1433   Allokutzneria albata DSM 44149 SDM40043.1    
 SAMN04489726_7042   Allokutzneria albata DSM 44149 SDN53268.1    
 SAMN04489726_6101   Allokutzneria albata DSM 44149 SDN33342.1    
 SAMN04489726_6262   Allokutzneria albata DSM 44149 SDN36637.1    
 HIMB5_00006290   alpha proteobacterium HIMB5 AFS47391.1    
 HIMB59_00010880   alpha proteobacterium HIMB59 AFS49272.1    
 WYH_01388 (NagZ)   Altererythrobacter atlanticus 26DY36 AKH42429.1    
 WYH_01400 (Bglx_1)   Altererythrobacter atlanticus 26DY36 AKH42441.1    
 WYH_02210 (fragment)   Altererythrobacter atlanticus 26DY36 AKH43243.1    
 WYH_02209 (Bglx_2) (fragment)   Altererythrobacter atlanticus 26DY36 AKH43242.1    
 A6F68_02906 (Bglx_2)   Altererythrobacter dongtanensis KCTC 22672 ANY21392.1    
 A6F68_00095 (Bglx_1)   Altererythrobacter dongtanensis KCTC 22672 ANY18631.1    
 A6F68_02816 (NagZ)   Altererythrobacter dongtanensis KCTC 22672 ANY21305.1    
 AMC99_02452   Altererythrobacter epoxidivorans GCMCC 1.7731 ALE17726.1    
 AMC99_01913   Altererythrobacter epoxidivorans GCMCC 1.7731 ALE17201.1    
 AM2010_213   Altererythrobacter marensis KCTC 22370 AKM06302.1    
 AM2010_2140   Altererythrobacter marensis KCTC 22370 AKM08200.1    
 AM2010_396   Altererythrobacter marensis KCTC 22370 AKM06484.1    
 A6F65_00908 (Bglx_1)   Altererythrobacter namhicola JCM 16345 ANU07218.1    
 A6F65_01042 (Bglx_2)   Altererythrobacter namhicola JCM 16345 ANU07351.1    
 A6F65_02304 (NagZ)   Altererythrobacter namhicola JCM 16345 ANU08587.1    
 AVL56_18430   Alteromonas addita R10SW13 AMJ96093.1    
 AVL56_08720   Alteromonas addita R10SW13 AMJ94378.1    
 AVL56_04185   Alteromonas addita R10SW13 AMJ93578.1    
 AVL56_02415   Alteromonas addita R10SW13 AMJ96405.1    
 AVL56_07305   Alteromonas addita R10SW13 AMJ96493.1    
 EP12_02755   Alteromonas australica DE170 AJP42775.1    
 EP13_02645   Alteromonas australica H 17 AIF97677.1    
 EP13_08205   Alteromonas australica H 17 AIF98665.1    
 EP13_17725   Alteromonas australica H 17 AIG00373.1    
 MASE_02155   Alteromonas macleodii ATCC 27126 AFS35995.1    
 MASE_07500   Alteromonas macleodii ATCC 27126 AFS37031.1    
 MASE_18065   Alteromonas macleodii ATCC 27126 AFS39103.1    
 MASE_19195   Alteromonas macleodii ATCC 27126 AFS39325.1    
 AVL55_08285   Alteromonas macleodii D7 AMJ98157.1    
 AVL55_02325   Alteromonas macleodii D7 AMJ97102.1    
 ACZ81_08140   Alteromonas macleodii HOT1A3 AMN11543.1    
 ACZ81_02415   Alteromonas macleodii HOT1A3 AMN10533.1    
 ACZ81_18565   Alteromonas macleodii HOT1A3 AMN13414.1    
 AMBAS45_02430   Alteromonas macleodii str. Balearic Sea AD45 AFT93966.1    
 AMBAS45_18490   Alteromonas macleodii str. Balearic Sea AD45 AFT97155.1    
 AMBAS45_08085   Alteromonas macleodii str. Balearic Sea AD45 AFT95092.1    
 AMBLS11_17515   Alteromonas macleodii str. Black Sea 11 AFT80068.1    
 AMBLS11_07520   Alteromonas macleodii str. Black Sea 11 AFT78085.1    
 AMBLS11_18495   Alteromonas macleodii str. Black Sea 11 AFT80264.1    
 AMBLS11_02435   Alteromonas macleodii str. Black Sea 11 AFT77079.1    
 AMEC673_02230   Alteromonas macleodii str. English Channel 673 AFT73149.1    
 AMEC673_07550   Alteromonas macleodii str. English Channel 673 AFT74204.1    
 AMEC673_18200   Alteromonas macleodii str. English Channel 673 AFT76316.1    
 I633_08505   Alteromonas mediterranea 615 AGP77758.1    
 BM523_17285   Alteromonas mediterranea AR43 APD95609.1    
 BM523_07265   Alteromonas mediterranea AR43 APD95938.1    
 BM523_02295   Alteromonas mediterranea AR43 APD92927.1    
 BM524_17165   Alteromonas mediterranea CP48 APD91393.1    
 BM524_07350   Alteromonas mediterranea CP48 APD91718.1    
 BM524_02350   Alteromonas mediterranea CP48 APD91635.1    
 BM525_17305   Alteromonas mediterranea CP49 APD99242.1    
 BM525_07305   Alteromonas mediterranea CP49 APD99573.1    
 BM525_02280   Alteromonas mediterranea CP49 APD96541.1    
 MADE_00592   Alteromonas mediterranea DE ACG64910.1
AEA96741.1
B4S1A2  
 MADE_02440   Alteromonas mediterranea DE ACG66736.1
AEA97801.1
B4RS37  
 MADE_03794   Alteromonas mediterranea DE ACG68084.1
AEA99928.1
B4S026  
 amad1_18980   Alteromonas mediterranea DE1 AFV87271.1    
 amad1_19790   Alteromonas mediterranea DE1 AFV87431.1    
 amad1_02700   Alteromonas mediterranea DE1 AFV84070.1    
 amad1_08340   Alteromonas mediterranea DE1 AFV85179.1    
 I533_02635   Alteromonas mediterranea MED64 AGP80520.1    
 I533_17850   Alteromonas mediterranea MED64 AGP83521.1    
 I533_07920   Alteromonas mediterranea MED64 AGP81560.1    
 BM526_07355   Alteromonas mediterranea RG65 APE03817.1    
 BM526_02320   Alteromonas mediterranea RG65 APE03727.1    
 BM526_17490   Alteromonas mediterranea RG65 APE03494.1    
 AV941_19550   Alteromonas mediterranea U10 AMJ84464.1    
 AV941_02630   Alteromonas mediterranea U10 AMJ81427.1    
 AV941_18765   Alteromonas mediterranea U10 AMJ84327.1    
 AV941_08290   Alteromonas mediterranea U10 AMJ84705.1    
 I607_17915   Alteromonas mediterranea U4 AGP87353.1    
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