Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC 3.2.1.21); xylan 1,4-β-xylosidase (EC 3.2.1.37); β-glucosylceramidase (EC 3.2.1.45); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,3-β-glucosidase (EC 3.2.1.58); glucan 1,4-β-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin β-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (20620); Uniprot accession (2560); PDB accession (117); 3D entries (40); cryst (4)
All (19731) Archaea (102) Bacteria (18469) Eukaryota (1058) Viruses (1) unclassified (101) Structure (40 - 4 cryst) Characterized (300)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 185 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 C8248_04805   Acidovorax avenae subsp. avenae QH1 AVT05372.1    
 C8242_04375   Acidovorax avenae subsp. avenae QHB1 AVT08818.1    
 C8235_04290   Acidovorax avenae subsp. avenae Sa2 AVT12184.1    
 C7Y68_05700   Acidovorax avenae subsp. avenae SH7 AVT19567.1    
 CBP34_14325   Acidovorax carolinensis NA3 ART52600.1    
 C8240_05165   Acidovorax cattleyae CAT98_1 AVS73523.1    
 Aave_1200   Acidovorax citrulli AAC00-1 ABM31792.1 A1TLF4  
 Dtpsy_2614   Acidovorax ebreus TPSY ACM34049.1 B9MDP0  
 Ajs_3261   Acidovorax sp. JS42 ABM43384.1 A1WAV9  
 C380_07280   Acidovorax sp. KKS102 AFU45165.1    
 CBP33_13795   Acidovorax sp. NA2 ART49067.1    
 CBP35_04630   Acidovorax sp. P3 ART54506.1    
 CBP36_14300   Acidovorax sp. P4 ART59842.1    
 BSY15_2612   Acidovorax sp. RAC01 AOG23366.1    
 ABCIP7010_0505   Acinetobacter baumannii CRL93243.1    
 ABR2090_3177   Acinetobacter baumannii CRX66076.1    
 ABR2091_0504   Acinetobacter baumannii CUW33926.1    
 CV094_12530   Acinetobacter baumannii AUG13311.1    
 Sequence 7933 from patent US 6562958   Acinetobacter baumannii AAQ30961.1    
 BS098_03430   Acinetobacter baumannii 11510 ATD19031.1    
 BS098_15740   Acinetobacter baumannii 11510 ATD21278.1    
 B7L42_03005   Acinetobacter baumannii 15A34 ARG19481.1    
 B6S64_09240   Acinetobacter baumannii 15A5 ARF92670.1    
 ABK1_0534   Acinetobacter baumannii 1656-2 ADX02168.1    
 BAL062_03419 (NagZ)   Acinetobacter baumannii 3027STDY5784958 SBS23479.1    
 Aba3207_13950   Acinetobacter baumannii 3207 ANC37654.1    
 RU84_15895   Acinetobacter baumannii 6200 AJB68295.1    
 Aba7804_18960   Acinetobacter baumannii 7804 ASO72683.1    
 ABA1_00570   Acinetobacter baumannii A1 AJF80490.1    
 BS103_02390   Acinetobacter baumannii A1296 ATI37508.1    
 A388_03342 (NagZ)   Acinetobacter baumannii A388 ATP88535.1    
 CBI29_00572 (NagZ)   Acinetobacter baumannii A85 ASF75969.1    
 AB57_0595   Acinetobacter baumannii AB0057 ACJ40016.1 B7I5F8  
 IX87_17065   Acinetobacter baumannii AB030 AIL80261.1    
 IX87_19925   Acinetobacter baumannii AB030 AIL80796.1    
 IX88_04765   Acinetobacter baumannii AB031 AIL74511.1    
 ACX61_16235   Acinetobacter baumannii Ab04-mff AKQ31888.1    
 AT570_09890   Acinetobacter baumannii AB042 APX49572.1    
 ABBFA_003042   Acinetobacter baumannii AB307-0294 ACJ59141.1 B7H078  
 CTY05_03016 (NagZ)   Acinetobacter baumannii AB307-0294 ATY45434.1    
 AXK18_05895   Acinetobacter baumannii AB34299 AQU56496.1    
 AWN74_02320   Acinetobacter baumannii Ab421_GEIH-2010 ANA36680.1    
 CTZ19_16830   Acinetobacter baumannii Ab4568 ATU57732.1    
 CTZ18_16335   Acinetobacter baumannii Ab4653 ATU54005.1    
 CTZ20_16605   Acinetobacter baumannii Ab4977 ATU50402.1    
 ABUW_3386 (NagZ)   Acinetobacter baumannii AB5075-UW AKA33082.1    
 A4U85_16085   Acinetobacter baumannii ab736 ARN32201.1    
 LX00_02555   Acinetobacter baumannii AbH12O-A2 AIS05279.1    
 LX00_09230   Acinetobacter baumannii AbH12O-A2 AIS06551.1    
 C2U32_17105   Acinetobacter baumannii ABNIH28 AUT39555.1    
 CTI08_17055   Acinetobacter baumannii AbPK1 ATR88882.1    
 A478_11365   Acinetobacter baumannii AC12 AHX29164.1    
 BL01_17060   Acinetobacter baumannii AC29 AIA53473.1    
 B856_09840   Acinetobacter baumannii AC30 AHX65566.1    
 ACICU_00502   Acinetobacter baumannii ACICU ACC55814.1 B2I3D6  
 BS064_18325   Acinetobacter baumannii AF-401 APJ20950.1    
 BS064_10620   Acinetobacter baumannii AF-401 APJ19523.1    
 BS065_16495   Acinetobacter baumannii AF-673 APJ24624.1    
 CSB68_2998 (fragment)   Acinetobacter baumannii AR_0052 AVI36564.1    
 AM435_16215   Acinetobacter baumannii AR_0056 AVN06181.1
AVE47112.1
   
 AM442_12380 (fragment)   Acinetobacter baumannii AR_0063 AVE55327.1    
 AM442_05640   Acinetobacter baumannii AR_0063 AVE54112.1    
 CSB70_0232   Acinetobacter baumannii AR_0070 AVI33668.1    
 AM457_06835   Acinetobacter baumannii AR_0078 AVF07308.1    
 AM462_11975   Acinetobacter baumannii AR_0083 AVN26249.1    
 AM467_02710   Acinetobacter baumannii AR_0088 AVN28410.1    
 AM480_08835   Acinetobacter baumannii AR_0101 AVO90956.1    
 AM480_17035   Acinetobacter baumannii AR_0101 AVO92428.1    
 AM481_01575   Acinetobacter baumannii AR_0102 AVO85855.1    
 AUO97_09895   Acinetobacter baumannii ATCC 17978 APP31106.1    
 A1S_0492   Acinetobacter baumannii ATCC 17978 ABO10945.2
ABO10945.1
A3M201  
 ACX60_15645   Acinetobacter baumannii ATCC 17978-mff AKQ28124.1    
 ABAYE3272   Acinetobacter baumannii AYE CAM88073.1    
 AYP_000516   Acinetobacter baumannii AYP-A2 ATU21816.1    
 AB994_3660   Acinetobacter baumannii B11911 KMV04845.1    
 AB987_0978   Acinetobacter baumannii B8300 KMV25585.1    
 AB895_2017   Acinetobacter baumannii B8342 KMV08762.1    
 BJAB07104_00548   Acinetobacter baumannii BJAB07104 AGQ12918.1    
 BJAB0715_00533   Acinetobacter baumannii BJAB0715 AGQ05179.1    
 BJAB0868_00551   Acinetobacter baumannii BJAB0868 AGQ09102.1    
 AN158_11160   Acinetobacter baumannii CA-17 AOM86754.1    
 B7L36_19740   Acinetobacter baumannii CBA7 ARG14934.1    
 AOT16_16175   Acinetobacter baumannii CMC-CR-MDR-Ab4 APQ86652.1    
 AOT18_16290   Acinetobacter baumannii CMC-CR-MDR-Ab66 APQ94303.1    
 AOT17_16125   Acinetobacter baumannii CMC-MDR-Ab59 APQ90512.1    
 ABD1_04640 (NagZ)   Acinetobacter baumannii D1279779 AGH34355.1    
 AN415_03444   Acinetobacter baumannii D36 ALJ89329.1    
 DLD53_10440   Acinetobacter baumannii DA33098 AWO16593.1    
 C6W84_06900   Acinetobacter baumannii DS002 AVP33862.1    
 DU202_00541 (NagZ)   Acinetobacter baumannii DU202 AOP61728.1    
 BKJ37_16680   Acinetobacter baumannii HRAB-85 APF45117.1    
 B7L46_11490   Acinetobacter baumannii HWBA8 ARG35509.1    
 IOMTU433_3303 (NagZ)   Acinetobacter baumannii IOMTU 433 BAP68061.1    
 B7L31_14655   Acinetobacter baumannii JBA13 ARG10327.1    
 KAB01_00538 (NagZ)   Acinetobacter baumannii KAB01 AOX68447.1    
 KAB02_00526 (NagZ)   Acinetobacter baumannii KAB02 AOX72262.1    
 KAB03_00570 (NagZ)   Acinetobacter baumannii KAB03 AOX76199.1    
 KAB04_03357 (NagZ)   Acinetobacter baumannii KAB04 AOX82777.1    
 KAB05_00545 (NagZ) (fragment)   Acinetobacter baumannii KAB05 AOX83947.1    
 KAB05_00544 (NagZ) (fragment)   Acinetobacter baumannii KAB05 AOX83946.1    
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