Glycoside Hydrolase Family 3

Known Activitiesβ-glucosidase (EC; xylan 1,4-β-xylosidase (EC; β-glucosylceramidase (EC; β-N-acetylhexosaminidase (EC; α-L-arabinofuranosidase (EC; glucan 1,3-β-glucosidase (EC; glucan 1,4-β-glucosidase (EC; isoprimeverose-producing oligoxyloglucan hydrolase (EC; coniferin β-glucosidase (EC; exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (12971); Uniprot accession (2561); PDB accession (98); 3D entries (32); cryst (4)
All (12144) Archaea (92) Bacteria (11127) Eukaryota (810) Viruses (1) unclassified (114) Structure (32 - 4 cryst) Characterized (287)

Last update: 2016-10-20 © Copyright 1998-2016
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