Glycoside Hydrolase Family 3

Activities in Family[retaining] β-NAcetylglucosaminoside phosphorylase (EC 2.4.1.-);
β-glycan phosphorylase (EC 2.4.1.-);
MLG exo-β-1,4-glucosidase (EC 3.2.1.-);
[retaining] xyloglucan-specific exo-β-1,4-glucosidase (EC 3.2.1.-);
α-L-arabinopyranosidase (EC 3.2.1.-);
Avenacinase (EC 3.2.1.-);
β-1,2-glucosidase (EC 3.2.1.-);
β-1,6-glucosidase (EC 3.2.1.-);
D-4,5-unsaturated β-glucuronyl hydrolase (EC 3.2.1.-);
Exo-β-1,3-1,4-glucanase (EC 3.2.1.-);
Terpenoid-β-1,2-glucosidase (EC 3.2.1.-);
Tomatinase β-1,2-glucosidase (EC 3.2.1.-);
[retaining] isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120);
Coniferin β-glucosidase (EC 3.2.1.126);
Chitosanase (EC 3.2.1.132);
Hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168);
Protodioscin 26-O-β-D-glucosidase (EC 3.2.1.186);
β-glucosidase (EC 3.2.1.21);
β-galactosidase (EC 3.2.1.23);
β-glucuronidase (EC 3.2.1.31);
Xylan β-1,4-xylosidase (EC 3.2.1.37);
β-D-fucosidase (EC 3.2.1.38);
β-glucosylceramidase (EC 3.2.1.45);
β-N-acetylhexosaminidase (EC 3.2.1.52);
α-L-arabinofuranosidase (EC 3.2.1.55);
Exo-β-1,3-glucanase (EC 3.2.1.58);
Endo-β-1,3(4)-glucanase / lichenase-laminarinase (EC 3.2.1.6);
β-1,3-xylosidase (EC 3.2.1.72);
Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73);
Exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74);
Endo-β-1,4-xylanase (EC 3.2.1.8);
Mechanism Retaining e
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that some enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (65828); Uniprot accession (383); PDB accession (204); 3D entries (59); cryst (3)


Last update: 2024-07-09 © Copyright 1998-2024
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