Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC; xylan 1,4-β-xylosidase (EC; β-glucosylceramidase (EC; β-N-acetylhexosaminidase (EC; α-L-arabinofuranosidase (EC; glucan 1,3-β-glucosidase (EC; glucan 1,4-β-glucosidase (EC; isoprimeverose-producing oligoxyloglucan hydrolase (EC; coniferin β-glucosidase (EC; exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (20155); Uniprot accession (2560); PDB accession (117); 3D entries (40); cryst (4)
All (19268) Archaea (102) Bacteria (18008) Eukaryota (1056) Viruses (1) unclassified (101) Structure (40 - 4 cryst) Characterized (300)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 181 |
Protein Name EC#OrganismGenBank UniprotPDB/3D
 BBX32_05215   Acinetobacter baumannii LAC4 APO57989.1    
 ABTJ_03282   Acinetobacter baumannii MDR-TJ AFI96850.1    
 ABZJ_00534   Acinetobacter baumannii MDR-ZJ06 AEP04994.1    
 AB237_2974 (NagZ)   Acinetobacter baumannii NCGM 237 BAN88889.1    
 SG90_016430   Acinetobacter baumannii ORAB01 ANB90028.1    
 U476_02785   Acinetobacter baumannii PKAB07 AHJ91985.1    
 G424_15065   Acinetobacter baumannii PR07 ANS22613.1    
 C5H40_18200   Acinetobacter baumannii S1; AB1A2 AVG28012.1    
 B7L45_16960   Acinetobacter baumannii SAA14 ARG03371.1    
 ABSDF3011   Acinetobacter baumannii SDF CAP02297.1    
 B7L38_08775   Acinetobacter baumannii SSA12 ARF96302.1    
 B7L40_08015   Acinetobacter baumannii SSA6 ARG24001.1    
 B7L43_09550   Acinetobacter baumannii SSMA17 ARG05664.1    
 ABTW07_0532   Acinetobacter baumannii TCDC-AB0715 ADX90969.1    
 M3Q_747   Acinetobacter baumannii TYTH-1 AFU36839.1    
 B7L41_04660   Acinetobacter baumannii USA15 ARG30548.1    
 B7L39_16780   Acinetobacter baumannii USA2 ARG29160.1    
 C6N18_03320   Acinetobacter baumannii WCHAB005078 AVN13215.1    
 C5B74_16260   Acinetobacter baumannii WCHAB005133 AVE91528.1    
 B7L35_09745   Acinetobacter baumannii WKA02 ARG39104.1    
 BS615_16485   Acinetobacter baumannii XDR-BJ83 APM50287.1    
 TE32_16975   Acinetobacter baumannii XH386 AKJ47211.1    
 AYR70_16130   Acinetobacter baumannii XH856 AML75737.1    
 AYR69_02500   Acinetobacter baumannii XH857 AML69572.1    
 AZE33_02535   Acinetobacter baumannii XH858 AMN00100.1    
 AYR68_01890   Acinetobacter baumannii XH859 AML65815.1    
 AYR67_15575   Acinetobacter baumannii XH860 AML64863.1    
 AXA63_00980   Acinetobacter baumannii YU-R612 AMC14115.1    
 P795_14825   Acinetobacter baumannii ZW85-1 AHB92690.1    
 BSR55_17650   Acinetobacter bereziniae XH901 ATZ65026.1    
 BUM88_02430   Acinetobacter calcoaceticus CA16 AQZ80568.1    
 NCTC7364_00510 (NagZ)   Acinetobacter calcoaceticus NCTC7364 SCD14581.1    
 DJ533_16330   Acinetobacter defluvii WCHA30 AWL30020.1    
 AOY20_01680   Acinetobacter equi 114 ALH94355.1    
 AS4_05650 (NagZ)   Acinetobacter guillouiae NBRC 110550 BAP35505.1    
 AHTJS_02545   Acinetobacter haemolyticus TJS01 APR69376.1    
 BSR56_02715   Acinetobacter haemolyticus XH900 ATZ66372.1    
 CTZ23_02390   Acinetobacter indicus SGAir0564 AVH13257.1    
 RZ95_14395   Acinetobacter johnsonii XBB1 ALV73937.1    
 BVL33_03815   Acinetobacter junii 65 APU47709.1    
 CS557_02540   Acinetobacter junii lzh-X15 ATU44426.1    
 CDG57_02825   Acinetobacter junii WCHAJ59 AWA47029.1    
 OTEC02_16285   Acinetobacter lactucae OTEC-02 ARD30182.1    
 BFG52_13795   Acinetobacter larvae BRTC-1 AOA59323.1    
 BVG18_03565   Acinetobacter lwoffii ZS207 AUC06057.1    
 RR32_15580   Acinetobacter nosocomialis 6411 AJB49462.1    
 AL533_14925   Acinetobacter nosocomialis FDAARGOS_129 AVF45566.1    
 DIW83_16810   Acinetobacter nosocomialis NCTC 8102 AWL20556.1    
 B7L44_18145   Acinetobacter nosocomialis SSA3 ARG18322.1    
 AOLE_16960   Acinetobacter oleivorans DR1 ADI92279.1 D8JGU7  
 AYJ52_07690   Acinetobacter pittii AP_882 AMM28323.1    
 IEC338SC_0965 (NagZ)   Acinetobacter pittii IEC338SC AMX18123.1    
 BDGL_003405 (NagZ)   Acinetobacter pittii PHEA-2 ADY83991.1    
 DBQ26_16945   Acinetobacter pittii WCHAP005046 AVZ06147.1    
 C2U64_18285   Acinetobacter pittii WCHAP005069 AUT35612.1    
 C6N19_17740   Acinetobacter pittii WCHAP100004 AVN19608.1    
 C6N17_16720   Acinetobacter pittii WCHAP100020 AVN23234.1    
 BVD86_12450   Acinetobacter pittii XJ88 AUM27627.1    
 BMU11_06555   Acinetobacter pittii YMC2010/8/T346 AQV15227.1    
 AsACE_CH00448 (NagZ)   Acinetobacter schindleri ACE APX61891.1    
 C0119_09650   Acinetobacter schindleri SGAir0122 AWD70486.1    
 BEN76_15685   Acinetobacter soli GFJ2 APV37365.1    
 C3F22_12180   Acinetobacter sp. ACNIH1 AUX90500.1    
 C3F34_04105   Acinetobacter sp. ACNIH2 AUX85331.1    
 ACIAD0551 (NagZ)   Acinetobacter sp. ADP1 CAG67476.1 Q6FEN2  
 A0J50_15015   Acinetobacter sp. DUT-2 AMO41821.1    
 BS636_03135   Acinetobacter sp. LoGeW2-3 ATO18728.1    
 A3K93_01685   Acinetobacter sp. NCu2D-2 ANF81027.1    
 AMD27_02445   Acinetobacter sp. TGL-Y2 AMW77862.1    
 AMQ28_05460   Acinetobacter sp. TTH0-4 ALD01857.1    
 CDG55_03485   Acinetobacter sp. WCHA45 AVZ84910.1    
 AHOG_16895 (BglX)   Actinoalloteichus hoggarensis DSM 45943 ASO21005.1    
 AHOG_01330 (Ybbd1)   Actinoalloteichus hoggarensis DSM 45943 ASO17932.1    
 AHOG_01955 (Ybbd2)   Actinoalloteichus hoggarensis DSM 45943 ASO18055.1    
 AHOG_07030 (Xyl3A)   Actinoalloteichus hoggarensis DSM 45943 ASO19054.1    
 TL08_02145   Actinoalloteichus hymeniacidonis HPA177(T) (=DSM 45092(T)) AOS61267.1    
 TL08_18435   Actinoalloteichus hymeniacidonis HPA177(T) (=DSM 45092(T)) AOS64482.1    
 TL08_01435   Actinoalloteichus hymeniacidonis HPA177(T) (=DSM 45092(T)) AOS61128.1    
 TL08_07580   Actinoalloteichus hymeniacidonis HPA177(T) (=DSM 45092(T)) AOS62334.1    
 TL08_15500   Actinoalloteichus hymeniacidonis HPA177(T) (=DSM 45092(T)) AOS63909.1    
 UA74_18875   Actinoalloteichus sp. ADI127-7 APU15803.1    
 UA74_01375   Actinoalloteichus sp. ADI127-7 APU12365.1    
 UA74_01990   Actinoalloteichus sp. ADI127-7 APU12485.1    
 UA74_07320   Actinoalloteichus sp. ADI127-7 APU13533.1    
 C1701_24110   Actinoalloteichus sp. AHMU CJ021 AUS80911.1    
 C1701_09645   Actinoalloteichus sp. AHMU CJ021 AUS81611.1    
 UA75_01995   Actinoalloteichus sp. GBA129-24 APU18438.1    
 UA75_01375   Actinoalloteichus sp. GBA129-24 APU18317.1    
 UA75_19365   Actinoalloteichus sp. GBA129-24 APU21863.1    
 UA75_07315   Actinoalloteichus sp. GBA129-24 APU19482.1    
 ACEE_06090   Actinobacillus equuli subsp. equuli 19392 AIZ79350.1    
 CHY23_00120 (NagZ)   Actinobacillus pleuropneumoniae KL 16 ASU14937.1    
 APPSER1_06075   Actinobacillus pleuropneumoniae serovar 1 str. 4074 AWG95546.1    
 APJL_1130   Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABY69686.1 B0BQ51  
 APL_1111   Actinobacillus pleuropneumoniae serovar 5b str. L20 ABN74203.1 A3N1B7  
 APP7_1168   Actinobacillus pleuropneumoniae serovar 7 str. AP76 ACE61820.1 B3GXZ7  
 MIDG2331_01151 (NagZ)   Actinobacillus pleuropneumoniae serovar 8 CUU52434.1    
 DDU33_06415   Actinobacillus porcitonsillarum 9953L55 AWI51133.1    
 Asuc_0211   Actinobacillus succinogenes 130Z ABR73591.1 A6VKU4  
 ASU1_05970   Actinobacillus suis ATCC 33415 AIJ31457.1    

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