Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC; xylan 1,4-β-xylosidase (EC; β-glucosylceramidase (EC; β-N-acetylhexosaminidase (EC; α-L-arabinofuranosidase (EC; glucan 1,3-β-glucosidase (EC; glucan 1,4-β-glucosidase (EC; isoprimeverose-producing oligoxyloglucan hydrolase (EC; coniferin β-glucosidase (EC; exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (18485); Uniprot accession (2560); PDB accession (112); 3D entries (36); cryst (4)
All (17620) Archaea (95) Bacteria (16398) Eukaryota (1025) Viruses (1) unclassified (101) Structure (36 - 4 cryst) Characterized (297)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 164 |
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CS557_02540   Acinetobacter junii lzh-X15 ATU44426.1    
 OTEC02_16285   Acinetobacter lactucae OTEC-02 ARD30182.1    
 BFG52_13795   Acinetobacter larvae BRTC-1 AOA59323.1    
 BVG18_03565   Acinetobacter lwoffii ZS207 AUC06057.1    
 RR32_15580   Acinetobacter nosocomialis 6411 AJB49462.1    
 B7L44_18145   Acinetobacter nosocomialis SSA3 ARG18322.1    
 AOLE_16960   Acinetobacter oleivorans DR1 ADI92279.1 D8JGU7  
 AYJ52_07690   Acinetobacter pittii AP_882 AMM28323.1    
 IEC338SC_0965 (NagZ)   Acinetobacter pittii IEC338SC AMX18123.1    
 BDGL_003405 (NagZ)   Acinetobacter pittii PHEA-2 ADY83991.1    
 BVD86_12450   Acinetobacter pittii XJ88 AUM27627.1    
 BMU11_06555   Acinetobacter pittii YMC2010/8/T346 AQV15227.1    
 AsACE_CH00448 (NagZ)   Acinetobacter schindleri ACE APX61891.1    
 BEN76_15685   Acinetobacter soli GFJ2 APV37365.1    
 ACIAD0551 (NagZ)   Acinetobacter sp. ADP1 CAG67476.1 Q6FEN2  
 A0J50_15015   Acinetobacter sp. DUT-2 AMO41821.1    
 BS636_03135   Acinetobacter sp. LoGeW2-3 ATO18728.1    
 A3K93_01685   Acinetobacter sp. NCu2D-2 ANF81027.1    
 AMD27_02445   Acinetobacter sp. TGL-Y2 AMW77862.1    
 AMQ28_05460   Acinetobacter sp. TTH0-4 ALD01857.1    
 AHOG_16895 (BglX)   Actinoalloteichus hoggarensis DSM 45943 ASO21005.1    
 AHOG_01330 (Ybbd1)   Actinoalloteichus hoggarensis DSM 45943 ASO17932.1    
 AHOG_01955 (Ybbd2)   Actinoalloteichus hoggarensis DSM 45943 ASO18055.1    
 AHOG_07030 (Xyl3A)   Actinoalloteichus hoggarensis DSM 45943 ASO19054.1    
 TL08_02145   Actinoalloteichus hymeniacidonis HPA177(T) (=DSM 45092(T)) AOS61267.1    
 TL08_18435   Actinoalloteichus hymeniacidonis HPA177(T) (=DSM 45092(T)) AOS64482.1    
 TL08_01435   Actinoalloteichus hymeniacidonis HPA177(T) (=DSM 45092(T)) AOS61128.1    
 TL08_07580   Actinoalloteichus hymeniacidonis HPA177(T) (=DSM 45092(T)) AOS62334.1    
 TL08_15500   Actinoalloteichus hymeniacidonis HPA177(T) (=DSM 45092(T)) AOS63909.1    
 UA74_18875   Actinoalloteichus sp. ADI127-7 APU15803.1    
 UA74_01375   Actinoalloteichus sp. ADI127-7 APU12365.1    
 UA74_01990   Actinoalloteichus sp. ADI127-7 APU12485.1    
 UA74_07320   Actinoalloteichus sp. ADI127-7 APU13533.1    
 UA75_01995   Actinoalloteichus sp. GBA129-24 APU18438.1    
 UA75_01375   Actinoalloteichus sp. GBA129-24 APU18317.1    
 UA75_19365   Actinoalloteichus sp. GBA129-24 APU21863.1    
 UA75_07315   Actinoalloteichus sp. GBA129-24 APU19482.1    
 ACEE_06090   Actinobacillus equuli subsp. equuli 19392 AIZ79350.1    
 CHY23_00120 (NagZ)   Actinobacillus pleuropneumoniae KL 16 ASU14937.1    
 APJL_1130   Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABY69686.1 B0BQ51  
 APL_1111   Actinobacillus pleuropneumoniae serovar 5b str. L20 ABN74203.1 A3N1B7  
 APP7_1168   Actinobacillus pleuropneumoniae serovar 7 str. AP76 ACE61820.1 B3GXZ7  
 MIDG2331_01151 (NagZ)   Actinobacillus pleuropneumoniae serovar 8 CUU52434.1    
 Asuc_0211   Actinobacillus succinogenes 130Z ABR73591.1 A6VKU4  
 ASU1_05970   Actinobacillus suis ATCC 33415 AIJ31457.1    
 ASU2_05900   Actinobacillus suis H91-0380 AFU19318.1    
 SAMEA4504061_01242 (NagZ)   Actinobacillus suis NCTC12996 SNV33018.1    
 IMCC26256_111541   Actinobacteria bacterium IMCC26256 AKL73815.1    
 BH719_04590   Actinomyces hongkongensis HKU8 AOS47226.1    
 AN27039_0168   Actinomyces naeslundii ATCC 27039 BAV83238.1    
 AN27039_0521 (fragment)   Actinomyces naeslundii ATCC 27039 BAV83591.1    
 AXE84_01570   Actinomyces oris T14V AMD98273.1    
 AXE84_02985   Actinomyces oris T14V AMD98510.1    
 AXF14_09230   Actinomyces radicidentis CCUG 36733 AMD88535.1    
 AXF14_01020   Actinomyces radicidentis CCUG 36733 AMD86440.1    
 AXF14_06400   Actinomyces radicidentis CCUG 36733 AMD88471.1    
 AXF14_07555   Actinomyces radicidentis CCUG 36733 AMD88498.1    
 SAMN04489714_0046   Actinomyces radingae DSM 9169 SDT85434.1    
 SAMN04489714_0364   Actinomyces radingae DSM 9169 SDT86876.1    
 SAMN04489714_2092   Actinomyces radingae DSM 9169 SDU08918.1    
 CHIBA101_0394   Actinomyces sp. Chiba101 BAW92265.1    
 CHIBA101_0960   Actinomyces sp. Chiba101 BAW92825.1    
 AM609_12070   Actinomyces sp. oral taxon 414 F0588 ALD00005.1    
 AM609_12760   Actinomyces sp. oral taxon 414 F0588 ALD00100.1    
 B6G06_05780   Actinomyces sp. pika_114 ARD41909.1    
 B6G06_08275   Actinomyces sp. pika_114 ARD42333.1    
 BK816_04130   Actinomyces sp. VUL4_3 AOZ72582.1    
 SAMN04489716_9137   Actinoplanes derwentensis DSM 43941 SDT80280.1    
 SAMN04489716_8925   Actinoplanes derwentensis DSM 43941 SDT79772.1    
 SAMN04489716_3817   Actinoplanes derwentensis DSM 43941 SDT44383.1    
 SAMN04489716_2323   Actinoplanes derwentensis DSM 43941 SDT03721.1    
 SAMN04489716_3760   Actinoplanes derwentensis DSM 43941 SDT43079.1    
 SAMN04489716_5293   Actinoplanes derwentensis DSM 43941 SDT65907.1    
 SAMN04489716_0422   Actinoplanes derwentensis DSM 43941 SDS27730.1    
 SAMN04489716_5707   Actinoplanes derwentensis DSM 43941 SDT69010.1    
 SAMN04489716_2968   Actinoplanes derwentensis DSM 43941 SDT24042.1    
 SAMN04489716_4816   Actinoplanes derwentensis DSM 43941 SDT60590.1    
 SAMN04489716_3767   Actinoplanes derwentensis DSM 43941 SDT43237.1    
 SAMN04489716_2455   Actinoplanes derwentensis DSM 43941 SDT08265.1    
 SAMN04489716_8777   Actinoplanes derwentensis DSM 43941 SDT79414.1    
 SAMN04489716_5494   Actinoplanes derwentensis DSM 43941 SDT67573.1    
 SAMN04489716_7925   Actinoplanes derwentensis DSM 43941 SDT77356.1    
 SAMN04489716_5122   Actinoplanes derwentensis DSM 43941 SDT64244.1    
 AFR_07935   Actinoplanes friuliensis DSM 7358 AGZ39876.1    
 AFR_08445   Actinoplanes friuliensis DSM 7358 AGZ39978.1    
 AFR_08670   Actinoplanes friuliensis DSM 7358 AGZ40023.1    
 AFR_11225   Actinoplanes friuliensis DSM 7358 AGZ40534.1    
 AFR_17980   Actinoplanes friuliensis DSM 7358 AGZ41874.1    
 AFR_25375   Actinoplanes friuliensis DSM 7358 AGZ43339.1    
 AFR_27495   Actinoplanes friuliensis DSM 7358 AGZ43760.1    
 AFR_31255 (fragment)   Actinoplanes friuliensis DSM 7358 AGZ44511.1    
 AFR_37100   Actinoplanes friuliensis DSM 7358 AGZ45674.1    
 AFR_17600   Actinoplanes friuliensis DSM 7358 AGZ41798.1    
 AFR_30325   Actinoplanes friuliensis DSM 7358 AGZ44325.1    
 AMIS_61630   Actinoplanes missouriensis 431 BAL91383.1    
 AMIS_63140   Actinoplanes missouriensis 431 BAL91534.1    
 AMIS_71580   Actinoplanes missouriensis 431 BAL92378.1    
 AMIS_11780   Actinoplanes missouriensis 431 BAL86398.1    
 AMIS_13050   Actinoplanes missouriensis 431 BAL86525.1    
 AMIS_14540   Actinoplanes missouriensis 431 BAL86674.1    

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