Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC 3.2.1.21); xylan 1,4-β-xylosidase (EC 3.2.1.37); β-glucosylceramidase (EC 3.2.1.45); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,3-β-glucosidase (EC 3.2.1.58); glucan 1,4-β-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin β-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (20620); Uniprot accession (2560); PDB accession (117); 3D entries (40); cryst (4)
All (19731) Archaea (102) Bacteria (18469) Eukaryota (1058) Viruses (1) unclassified (101) Structure (40 - 4 cryst) Characterized (300)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 185 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ACPL_7409   Actinoplanes sp. SE50/110 AEV88289.1
SLM04112.1
   
 SAMN04489717_2242   Actinopolymorpha singaporensis DSM 22024 SDS29728.1    
 SAMN04489717_2190   Actinopolymorpha singaporensis DSM 22024 SDS28184.1    
 SAMN04489717_2793   Actinopolymorpha singaporensis DSM 22024 SDS46973.1    
 CDG81_08555   Actinopolyspora erythraea YIM 90600 ASU78334.1    
 CDG81_06555   Actinopolyspora erythraea YIM 90600 ASU78027.1    
 CDG81_01400   Actinopolyspora erythraea YIM 90600 ASU80737.1    
 CDG81_10515   Actinopolyspora erythraea YIM 90600 ASU81029.1    
 CDG81_10545   Actinopolyspora erythraea YIM 90600 ASU81031.1    
 Amir_1826   Actinosynnema mirum DSM 43827 ACU35774.1 C6WE31  
 Amir_1982   Actinosynnema mirum DSM 43827 ACU35930.1 C6WFJ5  
 Amir_2168   Actinosynnema mirum DSM 43827 ACU36113.1 C6WI70  
 β-glucosidase (BglAm;Amir_2978) 3.2.1.21 Actinosynnema mirum DSM 43827 ACU36898.1 C6WRQ6  
 Amir_4021   Actinosynnema mirum DSM 43827 ACU37884.1 C6WFU8  
 Amir_4612   Actinosynnema mirum DSM 43827 ACU38445.1 C6WLQ2  
 Amir_4963   Actinosynnema mirum DSM 43827 ACU38789.1 C6WQU9  
 Amir_0273   Actinosynnema mirum DSM 43827 ACU34242.1 C6WFB0  
 Amir_4872   Actinosynnema mirum DSM 43827 ACU38698.1 C6WQK8  
 CNX65_11070   Actinosynnema pretiosum X47 ATE53768.1    
 CNX65_22935   Actinosynnema pretiosum X47 ATE55782.1    
 CNX65_09900   Actinosynnema pretiosum X47 ATE53565.1    
 CNX65_24095   Actinosynnema pretiosum X47 ATE58354.1    
 CNX65_01290   Actinosynnema pretiosum X47 ATE52089.1    
 CNX65_24475   Actinosynnema pretiosum X47 ATE56038.1    
 CNX65_20135   Actinosynnema pretiosum X47 ATE55306.1    
 CNX65_09115   Actinosynnema pretiosum X47 ATE53435.1    
 DDD63_05165   Actinotignum sp. 313 AWE43434.1    
 ADH66_13945   Acutalibacter muris KB18 ASB41663.1    
 ADH66_06455   Acutalibacter muris KB18 ASB40334.1    
 ADH66_11300   Acutalibacter muris KB18 ASB41189.1    
 ADH66_02435   Acutalibacter muris KB18 ASB39616.1    
 AEQU_2010   Adlercreutzia equolifaciens DSM 19450 BAN77979.1    
 TKWG_14580   Advenella kashmirensis WT001 AFK62972.1    
 MIM_c16440 (NagZ)   Advenella mimigardefordensis DPN7 AHG63727.1    
 Aeqsu_2742   Aequorivita sublithincola DSM 14238 AFL82193.1    
 AP3564_06510   Aeribacillus pallidus KCTC3564 ASS92288.1    
 AWM72_06325   Aerococcus sanguinicola CCUG43001 AMB94403.1    
 AWM72_03455   Aerococcus sanguinicola CCUG43001 AMB94947.1    
 AWM72_05450   Aerococcus sanguinicola CCUG43001 AMB94239.1    
 AWM72_08740 (fragment)   Aerococcus sanguinicola CCUG43001 AMB94838.1    
 AWM74_02695   Aerococcus urinaeequi CCUG28094 AMB97212.1    
 AWM74_05590   Aerococcus urinaeequi CCUG28094 AMB97737.1    
 APT62_02015   Aerococcus urinaeequi USDA-ARS-USMARC-56713 ALZ87295.1    
 APT62_08530   Aerococcus urinaeequi USDA-ARS-USMARC-56713 ALZ88484.1    
 AWM75_03160   Aerococcus urinaehominis CCUG42038B AMB99060.1    
 AWM75_03870   Aerococcus urinaehominis CCUG42038B AMB99193.1    
 AWM75_01260   Aerococcus urinaehominis CCUG42038B AMB98705.1    
 SAMN06295964_3115   Aeromicrobium choanae 9H-4 SKB10129.1    
 β-glucosidase (EryBI) 3.2.1.21 Aeromicrobium erythreum AAU93797.1 Q5Y9H4  
 AERYTH_15870   Aeromicrobium erythreum AR18 ALX06068.1    
 C3E78_05200   Aeromicrobium sp. 592 AWB91658.1    
 C3E78_14585   Aeromicrobium sp. 592 AWB93339.1    
 C3E78_07730   Aeromicrobium sp. 592 AWB92097.1    
 BOQ57_13780   Aeromonas aquatica MX16A APJ15926.1    
 VI35_10145   Aeromonas caviae 8LM ATP90572.1    
 MC60_002200   Aeromonas caviae FDAARGOS_72 AUU20906.1    
 MC60_008165   Aeromonas caviae FDAARGOS_72 AUU21964.1    
 NCTC12244_01045 (Bglx_1)   Aeromonas caviae NCTC12244 SQH58613.1    
 NCTC12244_02268 (Bglx_2)   Aeromonas caviae NCTC12244 SQH59794.1    
 CK627_12380   Aeromonas dhakensis KN-Mc-6U21 ASX11519.1    
 AH4AK4_1957   Aeromonas hydrophila 4AK4 AHE49412.1    
 VU14_08290   Aeromonas hydrophila AH10 AKA16864.1    
 TK34_08400   Aeromonas hydrophila AHNIH1 ANT67484.1    
 RY45_14135   Aeromonas hydrophila AL06-06 AJQ55163.1    
 V428_14770   Aeromonas hydrophila AL09-71 AHX33289.1    
 AhyD4_08545   Aeromonas hydrophila D4 ALZ79637.1    
 A9258_08275   Aeromonas hydrophila GYK1 ANR99615.1    
 V469_08320   Aeromonas hydrophila J-1 AJE35886.1    
 AS145_08790   Aeromonas hydrophila JBN2301 ALQ62975.1    
 C7K70_14035   Aeromonas hydrophila KN-Mc-1R2 AVP85082.1    
 AHML_14270   Aeromonas hydrophila ML09-119 AGM44624.1    
 U876_08305   Aeromonas hydrophila NJ-35 AKJ34087.1    
 V429_14790   Aeromonas hydrophila pc104A AHX70089.1    
 AHA_2689   Aeromonas hydrophila subsp. hydrophila ATCC 7966 ABK38668.1 A0KLP6  
 C1A23_16525   Aeromonas hydrophila subsp. hydrophila WCHAH045096 AWA07108.1    
 C1A23_12795   Aeromonas hydrophila subsp. hydrophila WCHAH045096 AWA06449.1    
 B224_2473   Aeromonas media WS AHX61067.1    
 B224_1238   Aeromonas media WS AHX60168.1    
 C7N77_14950   Aeromonas rivipollensis KN-Mc-11N1 AVP94343.1    
 CHQ57_08720   Aeromonas salmonicida A527 ATU97523.1    
 CE456_15330   Aeromonas salmonicida S121 ASI23802.1    
 CE463_15350   Aeromonas salmonicida S44 ASI28121.1    
 CE462_14300   Aeromonas salmonicida S68 ASI32253.1    
 BHG40_12355   Aeromonas salmonicida subsp. masoucida RFAS1 ATD38638.1    
 Asalp_20970   Aeromonas salmonicida subsp. pectinolytica 34mel ATP09269.1    
 ASA_2542   Aeromonas salmonicida subsp. salmonicida A449 ABO90571.1 A4SNU9  
 C2U37_19090   Aeromonas sp. ASNIH1 AUZ81512.1    
 C3F36_21385   Aeromonas sp. ASNIH2 AUY11769.1    
 C3F36_05065   Aeromonas sp. ASNIH2 AUY08989.1    
 C2U39_10055   Aeromonas sp. ASNIH3 AUV12488.1    
 C2U39_16945   Aeromonas sp. ASNIH3 AUV13696.1    
 C2U40_07215   Aeromonas sp. ASNIH4 AUZ77771.1    
 C2U30_20195   Aeromonas sp. ASNIH5 AUT44438.1    
 C2U30_03620   Aeromonas sp. ASNIH5 AUT40869.1    
 C2U47_20550   Aeromonas sp. ASNIH7 AUV18631.1    
 C2U47_04090   Aeromonas sp. ASNIH7 AUV15910.1    
 CK910_13770   Aeromonas sp. CA23 ATL99427.1    
 O23A_p0911   Aeromonas sp. O23A ARW81658.1    
 B565_1488   Aeromonas veronii B565 AEB49523.1    
 CVS41_17540   Aeromonas veronii X11 ATY78788.1    
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