Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC; xylan 1,4-β-xylosidase (EC; β-glucosylceramidase (EC; β-N-acetylhexosaminidase (EC; α-L-arabinofuranosidase (EC; glucan 1,3-β-glucosidase (EC; glucan 1,4-β-glucosidase (EC; isoprimeverose-producing oligoxyloglucan hydrolase (EC; coniferin β-glucosidase (EC; exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (18956); Uniprot accession (2560); PDB accession (114); 3D entries (37); cryst (4)
All (18090) Archaea (96) Bacteria (16863) Eukaryota (1029) Viruses (1) unclassified (101) Structure (37 - 4 cryst) Characterized (298)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 169 |
Protein Name EC#OrganismGenBank UniprotPDB/3D
 MC60_002200   Aeromonas caviae FDAARGOS_72 AUU20906.1    
 MC60_008165   Aeromonas caviae FDAARGOS_72 AUU21964.1    
 CK627_12380   Aeromonas dhakensis KN-Mc-6U21 ASX11519.1    
 AH4AK4_1957   Aeromonas hydrophila 4AK4 AHE49412.1    
 VU14_08290   Aeromonas hydrophila AH10 AKA16864.1    
 TK34_08400   Aeromonas hydrophila AHNIH1 ANT67484.1    
 RY45_14135   Aeromonas hydrophila AL06-06 AJQ55163.1    
 V428_14770   Aeromonas hydrophila AL09-71 AHX33289.1    
 AhyD4_08545   Aeromonas hydrophila D4 ALZ79637.1    
 A9258_08275   Aeromonas hydrophila GYK1 ANR99615.1    
 V469_08320   Aeromonas hydrophila J-1 AJE35886.1    
 AS145_08790   Aeromonas hydrophila JBN2301 ALQ62975.1    
 AHML_14270   Aeromonas hydrophila ML09-119 AGM44624.1    
 U876_08305   Aeromonas hydrophila NJ-35 AKJ34087.1    
 V429_14790   Aeromonas hydrophila pc104A AHX70089.1    
 AHA_2689   Aeromonas hydrophila subsp. hydrophila ATCC 7966 ABK38668.1 A0KLP6  
 B224_2473   Aeromonas media WS AHX61067.1    
 B224_1238   Aeromonas media WS AHX60168.1    
 CHQ57_08720   Aeromonas salmonicida A527 ATU97523.1    
 CE456_15330   Aeromonas salmonicida S121 ASI23802.1    
 CE463_15350   Aeromonas salmonicida S44 ASI28121.1    
 CE462_14300   Aeromonas salmonicida S68 ASI32253.1    
 BHG40_12355   Aeromonas salmonicida subsp. masoucida RFAS1 ATD38638.1    
 Asalp_20970   Aeromonas salmonicida subsp. pectinolytica 34mel ATP09269.1    
 ASA_2542   Aeromonas salmonicida subsp. salmonicida A449 ABO90571.1 A4SNU9  
 C2U37_19090   Aeromonas sp. ASNIH1 AUZ81512.1    
 C3F36_21385   Aeromonas sp. ASNIH2 AUY11769.1    
 C3F36_05065   Aeromonas sp. ASNIH2 AUY08989.1    
 C2U39_10055   Aeromonas sp. ASNIH3 AUV12488.1    
 C2U39_16945   Aeromonas sp. ASNIH3 AUV13696.1    
 C2U40_07215   Aeromonas sp. ASNIH4 AUZ77771.1    
 C2U30_20195   Aeromonas sp. ASNIH5 AUT44438.1    
 C2U30_03620   Aeromonas sp. ASNIH5 AUT40869.1    
 C2U47_20550   Aeromonas sp. ASNIH7 AUV18631.1    
 C2U47_04090   Aeromonas sp. ASNIH7 AUV15910.1    
 CK910_13770   Aeromonas sp. CA23 ATL99427.1    
 O23A_p0911   Aeromonas sp. O23A ARW81658.1    
 B565_1488   Aeromonas veronii B565 AEB49523.1    
 CVS41_17540   Aeromonas veronii X11 ATY78788.1    
 SAMN05444050_1740   Afipia sp. GAS231 SDN51061.1    
 SAMN05444050_0178   Afipia sp. GAS231 SDM91734.1    
 SAMN05444050_3829   Afipia sp. GAS231 SDO31453.1    
 ACT75_03025   Aggregatibacter actinomycetemcomitans 624 AMQ93564.1    
 ANH9381_0139   Aggregatibacter actinomycetemcomitans ANH9381 AEW76178.1    
 D11S_1953   Aggregatibacter actinomycetemcomitans D11S-1 ACX83307.1 C9R671  
 D7S_01975   Aggregatibacter actinomycetemcomitans D7S-1 AFI87695.1    
 CF65_02990   Aggregatibacter actinomycetemcomitans HK1651 AHN72991.1
 BBH51_10955   Aggregatibacter actinomycetemcomitans IDH781 ANU83127.1    
 AANUM_2349   Aggregatibacter actinomycetemcomitans NUM4039 BAS49580.1    
 ACT74_06460   Aggregatibacter actinomycetemcomitans VT1169 AMQ92264.1    
 NT05HA_0109   Aggregatibacter aphrophilus NJ8700 ACS96551.1
 ADJ80_05085   Aggregatibacter aphrophilus W1043 AKU63169.1    
 Atu1709   Agrobacterium fabrum str. C58 AAL42709.1
 Arad_9745 (BglSf)   Agrobacterium radiobacter K84 ACM30723.1 B9JLI7  
 Arad_2121   Agrobacterium radiobacter K84 ACM26386.1 B9JEG5  
 Arad_12248   Agrobacterium radiobacter K84 ACM31268.1 B9JQ49  
 Arad_7149   Agrobacterium radiobacter K84 ACM28713.1 B9JLZ9  
 Arad_9829 (BglsF)   Agrobacterium radiobacter K84 ACM30787.1 B9JLQ1  
 B0909_20330   Agrobacterium rhizogenes K599 AQS64601.1    
 B0909_04485   Agrobacterium rhizogenes K599 AQS63165.1    
 AGROH133_06635   Agrobacterium sp. H13-3 ADY64638.1    
 BSY240_875   Agrobacterium sp. RAC06 AOG10948.1    
 BSY240_624 (BglB)   Agrobacterium sp. RAC06 AOG09514.1    
 coniferin β-glucosidase (Cbg1;Cbg-1)
Agrobacterium tumefaciens AAA22082.1 P27034  
 Ach5_16380   Agrobacterium tumefaciens Ach5 AKC07414.1    
 X971_1687   Agrobacterium tumefaciens LBA4213 (Ach5) AHK01564.1    
 AWN88_13505   Agrobacterium tumefaciens S33 AMD59291.1    
 Avi_0107   Agrobacterium vitis S4 ACM35056.1 B9JY26  
 Avi_2673   Agrobacterium vitis S4 ACM36922.1 B9JXE4  
 Avi_6257   Agrobacterium vitis S4 ACM39228.1 B9K2Y0  
 SAMN04489719_1319   Agrococcus carbonis DSM 22965 SDS00498.1    
 SAMN04489720_0891   Agrococcus jejuensis DSM 22002 SDH30777.1    
 SAMN04489720_1193   Agrococcus jejuensis DSM 22002 SDH41453.1    
 SAMN04489720_0909   Agrococcus jejuensis DSM 22002 SDH31152.1    
 ATC03_11050   Agromyces aureus AR33 ANJ27182.1    
 ATC03_09955   Agromyces aureus AR33 ANJ28837.1    
 ATC03_05190   Agromyces aureus AR33 ANJ26209.1    
 ATC03_05935   Agromyces aureus AR33 ANJ26323.1    
 ATC03_01080   Agromyces aureus AR33 ANJ28604.1    
 ATC03_05185   Agromyces aureus AR33 ANJ26208.1    
 ATC03_11045   Agromyces aureus AR33 ANJ27181.1    
 ATC03_10825   Agromyces aureus AR33 ANJ27144.1    
 ATC03_00340   Agromyces aureus AR33 ANJ25446.1    
 ATC03_18970   Agromyces aureus AR33 ANJ29083.1    
 SAMN04489721_2260   Agromyces flavus CPCC 202695 SDS97270.1    
 SAMN04489721_2000   Agromyces flavus CPCC 202695 SDS83745.1    
 SAMN04489721_2103   Agromyces flavus CPCC 202695 SDS89294.1    
 SAMN04489721_0700   Agromyces flavus CPCC 202695 SDS05457.1    
 SAMN04489721_1130   Agromyces flavus CPCC 202695 SDS32759.1    
 SAMN04489721_0302   Agromyces flavus CPCC 202695 SDR79552.1    
 PYTT_2532   Akkermansia glycaniphila SEI01009.1    
 PYTT_1900   Akkermansia glycaniphila SEH93924.1    
 PYTT_2056   Akkermansia glycaniphila SEH95655.1    
 Amuc_2109   Akkermansia muciniphila ATCC BAA-835 ACD05918.1 B2UPP0  
 A4V05_06480   Akkermansia muciniphila YL44 ANU61102.1
 CDA61_02005   Alcaligenes faecalis BDB4 ASC89223.1    
 CPY64_10550   Alcaligenes faecalis DSM 30030 ATI00145.1    
 AFA_11820   Alcaligenes faecalis JQ135 ASR90082.1    
 ALFP_2284   Alcaligenes faecalis P156 ARP54171.1    
 UZ73_02215   Alcaligenes faecalis ZD02 ALO37180.1    

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