Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC 3.2.1.21); xylan 1,4-β-xylosidase (EC 3.2.1.37); β-glucosylceramidase (EC 3.2.1.45); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,3-β-glucosidase (EC 3.2.1.58); glucan 1,4-β-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin β-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (21009); Uniprot accession (2560); PDB accession (117); 3D entries (40); cryst (4)
All (20118) Archaea (104) Bacteria (18846) Eukaryota (1066) Viruses (1) unclassified (101) Structure (40 - 4 cryst) Characterized (300)
| 1 | ... | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | ... | 189 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 A4R43_40510   Amycolatopsis albispora WP1 AXB47955.1    
 A4R43_11420   Amycolatopsis albispora WP1 AXB43081.1    
 A4R43_09570   Amycolatopsis albispora WP1 AXB42746.1    
 A4R43_35125   Amycolatopsis albispora WP1 AXB49051.1    
 A4R43_09430   Amycolatopsis albispora WP1 AXB42723.1    
 A4R43_06385   Amycolatopsis albispora WP1 AXB42206.1    
 A4R43_24290   Amycolatopsis albispora WP1 AXB45233.1    
 A4R43_24295   Amycolatopsis albispora WP1 AXB45234.1    
 AJAP_32910   Amycolatopsis japonica MG417-CF17 AIG79396.1    
 AJAP_15280   Amycolatopsis japonica MG417-CF17 AIG75932.1    
 AJAP_39560   Amycolatopsis japonica MG417-CF17 AIG80692.1    
 AJAP_04360 (fragment)   Amycolatopsis japonica MG417-CF17 AIG73794.1    
 AJAP_34900   Amycolatopsis japonica MG417-CF17 AIG79787.1    
 SAMN04489733_7504   Amycolatopsis keratiniphila FH 1893 SDU64033.1    
 SAMN04489733_4580   Amycolatopsis keratiniphila FH 1893 SDU46216.1    
 SAMN04489733_6677   Amycolatopsis keratiniphila FH 1893 SDU59369.1    
 SAMN04489733_2481   Amycolatopsis keratiniphila FH 1893 SDU25865.1    
 SAMN04489733_4989   Amycolatopsis keratiniphila FH 1893 SDU49307.1    
 SAMN04489733_0935   Amycolatopsis keratiniphila FH 1893 SDU07690.1    
 SAMN04489733_2480   Amycolatopsis keratiniphila FH 1893 SDU25854.1    
 BB31_15885   Amycolatopsis lurida NRRL 2430 AJK54761.1    
 BB31_03175 (fragment)   Amycolatopsis lurida NRRL 2430 AJK52497.1    
 BB31_29270   Amycolatopsis lurida NRRL 2430 AJK57255.1    
 BB31_29275   Amycolatopsis lurida NRRL 2430 AJK57256.1    
 BB31_01795   Amycolatopsis lurida NRRL 2430 AJK52236.1    
 BB31_23570   Amycolatopsis lurida NRRL 2430 AJK56201.1    
 BB31_27770   Amycolatopsis lurida NRRL 2430 AJK56964.1    
 BB31_29760   Amycolatopsis lurida NRRL 2430 AJK57324.1    
 B737_5187 (BglX)   Amycolatopsis mediterranei RB AGT85851.1    
 B737_4313 (NagZ)   Amycolatopsis mediterranei RB AGT84977.1    
 B737_0937   Amycolatopsis mediterranei RB AGT81601.1    
 B737_8484   Amycolatopsis mediterranei RB AGT89144.1    
 B737_8676   Amycolatopsis mediterranei RB AGT89336.1    
 B737_1288   Amycolatopsis mediterranei RB AGT81952.1    
 B737_7157   Amycolatopsis mediterranei RB AGT87819.1    
 B737_1706 (BglX)   Amycolatopsis mediterranei RB AGT82370.1    
 B737_8004   Amycolatopsis mediterranei RB AGT88665.1    
 B737_4296   Amycolatopsis mediterranei RB AGT84960.1    
 B737_4452 (BglX)   Amycolatopsis mediterranei RB AGT85116.1    
 B737_7268 (BglX)   Amycolatopsis mediterranei RB AGT87929.1    
 B737_7462   Amycolatopsis mediterranei RB AGT88123.1    
 B737_3954   Amycolatopsis mediterranei RB AGT84618.1    
 RAM_22230   Amycolatopsis mediterranei S699 AEK42926.1
AFO77849.1
   
 RAM_06570   Amycolatopsis mediterranei S699 AEK39806.1
AFO74823.1
   
 RAM_22950   Amycolatopsis mediterranei S699 AEK43070.1
AFO77988.1
   
 RAM_38915   Amycolatopsis mediterranei S699 AEK46250.1
AFO80995.1
   
 RAM_37935   Amycolatopsis mediterranei S699 AEK46054.1
AFO80801.1
   
 RAM_37330   Amycolatopsis mediterranei S699 AEK45933.1
AFO80691.1
   
 RAM_44210   Amycolatopsis mediterranei S699 AEK47309.1
AFO82015.1
   
 RAM_22145   Amycolatopsis mediterranei S699 AEK42909.1
AFO77832.1
   
 RAM_41745   Amycolatopsis mediterranei S699 AEK46816.1
AFO81536.1
   
 RAM_20400   Amycolatopsis mediterranei S699 AEK42560.1
AFO77490.1
   
 RAM_45195   Amycolatopsis mediterranei S699 AEK47506.1
AFO82207.1
   
 RAM_04785   Amycolatopsis mediterranei S699 AEK39449.1
AFO74472.1
   
 AMES_1705 (BglX)   Amycolatopsis mediterranei S699 AFO75241.1
AEK40235.1
   
 AMES_5187 (BglX)   Amycolatopsis mediterranei S699 AFO78723.1
AEK43826.1
   
 AMED_0939   Amycolatopsis mediterranei U32 ADJ42758.1 D8I3K3  
 AMED_1295   Amycolatopsis mediterranei U32 ADJ43109.1 D8I6V9  
 AMED_1718 (BglX)   Amycolatopsis mediterranei U32 ADJ43529.1 D8HNH8  
 AMED_4002   Amycolatopsis mediterranei U32 ADJ45779.1 D8HPV7  
 AMED_4348   Amycolatopsis mediterranei U32 ADJ46121.1 D8HSD4  
 AMED_4507 (BglX)   Amycolatopsis mediterranei U32 ADJ46277.1 D8HTY3  
 AMED_5251 (BglX)   Amycolatopsis mediterranei U32 ADJ47013.1 D8I2Y8  
 AMED_7267   Amycolatopsis mediterranei U32 ADJ48983.1 D8I7W0  
 AMED_7379 (BglX)   Amycolatopsis mediterranei U32 ADJ49093.1 D8I9C6  
 AMED_7574   Amycolatopsis mediterranei U32 ADJ49287.1 D8HP73  
 AMED_8125   Amycolatopsis mediterranei U32 ADJ49828.1 D8HLX3  
 AMED_8808   Amycolatopsis mediterranei U32 ADJ50501.1 D8HK80  
 AMED_4365   Amycolatopsis mediterranei U32 ADJ46138.1 D8HSF1  
 AMED_8614   Amycolatopsis mediterranei U32 ADJ50309.1 D8HJN2  
 AMETH_0372   Amycolatopsis methanolica 239 AIJ20464.1    
 AMETH_3402 (CelD)   Amycolatopsis methanolica 239 AIJ23494.1    
 AMETH_6610 (NagA)   Amycolatopsis methanolica 239 AIJ26702.1    
 AMETH_2236 (BglX) (fragment)   Amycolatopsis methanolica 239 AIJ22328.1    
 SD37_02670   Amycolatopsis orientalis B-37 ANN14664.1    
 SD37_05955   Amycolatopsis orientalis B-37 ANN15242.1    
 SD37_20795   Amycolatopsis orientalis B-37 ANN17846.1    
 SD37_36580   Amycolatopsis orientalis B-37 ANN20566.1    
 SD37_23495   Amycolatopsis orientalis B-37 ANN18309.1    
 SD37_34545   Amycolatopsis orientalis B-37 ANN20212.1    
 SD37_24025   Amycolatopsis orientalis B-37 ANN18396.1    
 SD37_23490   Amycolatopsis orientalis B-37 ANN18308.1    
 AORI_0933   Amycolatopsis orientalis HCCB10007 AGM03522.1    
 AORI_1329 (NagZ)   Amycolatopsis orientalis HCCB10007 AGM03918.1    
 AORI_4858   Amycolatopsis orientalis HCCB10007 AGM07442.1    
 AORI_6949 (NagZ)   Amycolatopsis orientalis HCCB10007 AGM09531.1    
 AORI_7586 (NagZ)   Amycolatopsis orientalis HCCB10007 AGM10168.1    
 CU254_36600   Amycolatopsis sp. AA4 ATY16856.1    
 CU254_31840   Amycolatopsis sp. AA4 ATY14503.1    
 CU254_21010   Amycolatopsis sp. AA4 ATY12660.1    
 CU254_20115   Amycolatopsis sp. AA4 ATY12500.1    
 CU254_33170   Amycolatopsis sp. AA4 ATY16768.1    
 CU254_17175   Amycolatopsis sp. AA4 ATY12002.1    
 BKN51_38780   Amycolatopsis sp. BJA-103 AUI64979.1    
 BKN51_27950   Amycolatopsis sp. BJA-103 AUI61628.1    
 BKN51_40740   Amycolatopsis sp. BJA-103 AUI63861.1    
 BKN51_40485   Amycolatopsis sp. BJA-103 AUI63815.1    
 BKN51_09335   Amycolatopsis sp. BJA-103 AUI64328.1    
 BKN51_31215   Amycolatopsis sp. BJA-103 AUI62194.1    
 Betα-glucosidase (Var20)   Amycolatopsis sp. DEM30355 AUO14861.1    
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