Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC 3.2.1.21); xylan 1,4-β-xylosidase (EC 3.2.1.37); β-glucosylceramidase (EC 3.2.1.45); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,3-β-glucosidase (EC 3.2.1.58); glucan 1,4-β-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin β-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (17231); Uniprot accession (2560); PDB accession (105); 3D entries (33); cryst (4)
All (16380) Archaea (94) Bacteria (15236) Eukaryota (949) Viruses (1) unclassified (100) Structure (33 - 4 cryst) Characterized (293)
| 1 | ... | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | ... | 153 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AL755_01155   Arthrobacter sp. ERGS1:01 ALE04344.1    
 AL755_16165   Arthrobacter sp. ERGS1:01 ALE07901.1    
 AL755_02400   Arthrobacter sp. ERGS1:01 ALE04537.1    
 AL755_04145   Arthrobacter sp. ERGS1:01 ALE04880.1    
 Arth_0505   Arthrobacter sp. FB24 ABK01904.1 A0JS84  
 Arth_1839   Arthrobacter sp. FB24 ABK03229.1 A0JW09  
 Arth_2890   Arthrobacter sp. FB24 ABK04269.1 A0JYZ9  
 Arth_3149   Arthrobacter sp. FB24 ABK04527.1 A0JZQ7  
 AHiyo4_39180 (fragment)   Arthrobacter sp. Hiyo4 BAS10496.1    
 AHiyo4_05730   Arthrobacter sp. Hiyo4 BAS07151.1    
 AHiyo4_35440   Arthrobacter sp. Hiyo4 BAS10122.1    
 AHiyo4_39170 (fragment)   Arthrobacter sp. Hiyo4 BAS10495.1    
 AHiyo8_09020 (fragment)   Arthrobacter sp. Hiyo8 BAS12599.1    
 AHiyo8_54070 (fragment)   Arthrobacter sp. Hiyo8 BAS17104.1    
 AHiyo8_54060 (fragment)   Arthrobacter sp. Hiyo8 BAS17103.1    
 AHiyo8_39670   Arthrobacter sp. Hiyo8 BAS15664.1    
 AHiyo8_54050 (fragment)   Arthrobacter sp. Hiyo8 BAS17102.1    
 AHiyo8_09030 (fragment)   Arthrobacter sp. Hiyo8 BAS12600.1    
 AHiyo8_52450 (fragment)   Arthrobacter sp. Hiyo8 BAS16942.1    
 AHiyo8_30720 (fragment)   Arthrobacter sp. Hiyo8 BAS14769.1    
 AHiyo8_52460 (fragment)   Arthrobacter sp. Hiyo8 BAS16943.1    
 UM93_02520   Arthrobacter sp. IHBB 11108 AJT42817.1    
 UM93_07465   Arthrobacter sp. IHBB 11108 AJT42963.1    
 AFL94_04045   Arthrobacter sp. LS16 ALD63246.1    
 AFL94_01800   Arthrobacter sp. LS16 ALD62894.1    
 ART_3861   Arthrobacter sp. PAMC 25486 AIY03460.1    
 ART_0502   Arthrobacter sp. PAMC 25486 AIY00101.1    
 ART_1629   Arthrobacter sp. PAMC 25486 AIY01228.1    
 BWQ92_16920   Arthrobacter sp. QXT-31 APX04587.1    
 ARUE_c10900   Arthrobacter sp. Rue61a AFR28011.1    
 ARUE_c42180 (YbbD)   Arthrobacter sp. Rue61a AFR31090.1    
 ARUE_c20320   Arthrobacter sp. Rue61a AFR28937.1    
 ARUE_c06220   Arthrobacter sp. Rue61a AFR27557.1    
 ARUE_c18440 (Bglx1)   Arthrobacter sp. Rue61a AFR28750.1    
 ARUE_c18720 (Bglx2)   Arthrobacter sp. Rue61a AFR28778.1    
 ARUE_c28990 (NagZ)   Arthrobacter sp. Rue61a AFR29785.1    
 ARUE_c18700   Arthrobacter sp. Rue61a AFR28776.1    
 ASPU41_04865   Arthrobacter sp. U41 AOT02777.1    
 ATC04_16255   Arthrobacter sp. YC-RL1 ALQ31942.1    
 ATC04_13790 (fragment)   Arthrobacter sp. YC-RL1 ALQ31515.1    
 CGK93_22845   Arthrobacter sp. YN ASN22181.1    
 CGK93_05925   Arthrobacter sp. YN ASN19278.1    
 CGK93_15850   Arthrobacter sp. YN ASN20985.1    
 CGK93_02860   Arthrobacter sp. YN ASN18761.1    
 CGK93_03435   Arthrobacter sp. YN ASN18862.1    
 ARZXY2_3398   Arthrobacter sp. ZXY-2 AOY72912.1    
 ARZXY2_2865 (BglX)   Arthrobacter sp. ZXY-2 AOY72390.1    
 ARZXY2_3319 (BglX)   Arthrobacter sp. ZXY-2 AOY72833.1    
 ARZXY2_4524 (BglX) (fragment)   Arthrobacter sp. ZXY-2 AOY74023.1    
 ARZXY2_1518 (BglX)   Arthrobacter sp. ZXY-2 AOY71071.1    
 ARZXY2_4689 (BglX)   Arthrobacter sp. ZXY-2 AOY74188.1    
 ARZXY2_940   Arthrobacter sp. ZXY-2 AOY70501.1    
 NIES39_A02950   Arthrospira platensis NIES-39 BAI88134.1 D4ZXQ6  
 AP285_01165   Arthrospira platensis YZ AMW26811.1    
 ARTHRO_61029   Arthrospira sp. PCC 8005 CDM98428.1    
 Asbog_00768   Asaia bogorensis NBRC 16594 BAT19063.1    
 Astex_1219   Asticcacaulis excentricus CB 48 ADU12894.1 C5SPX4  
 Astex_1355   Asticcacaulis excentricus CB 48 ADU13025.1 C5SMQ9  
 Astex_1373   Asticcacaulis excentricus CB 48 ADU13043.1    
 Astex_1600   Asticcacaulis excentricus CB 48 ADU13266.1 C5SGS3  
 Astex_1640   Asticcacaulis excentricus CB 48 ADU13306.1 C5SGW3  
 Astex_1947   Asticcacaulis excentricus CB 48 ADU13610.1 C5SG86  
 Astex_2467   Asticcacaulis excentricus CB 48 ADU14118.1 C5SNU6  
 Astex_2724   Asticcacaulis excentricus CB 48 ADU14363.1 C5SHN3  
 Astex_3224   Asticcacaulis excentricus CB 48 ADU14859.1 C5SP67  
 Astex_3315   Asticcacaulis excentricus CB 48 ADU14949.1 C5SLH9  
 Astex_3402   Asticcacaulis excentricus CB 48 ADU15035.1 C5SN83  
 Astex_3404   Asticcacaulis excentricus CB 48 ADU15037.1 C5SN85  
 NIES50_64390   Aulosira laxa NIES-50 BAZ77806.1    
 AUMI_16310   Aurantimicrobium minutum KNC BAU99173.1    
 β-hexosaminidase   Aurantimonas manganoxydans DSM 21871 BAT29280.1    
 SAMN04489747_1434   Auraticoccus monumenti MON 2.2 SDD64795.1    
 SAMN04489747_1386   Auraticoccus monumenti MON 2.2 SDD62608.1    
 SAMN04489747_2715   Auraticoccus monumenti MON 2.2 SDE17738.1    
 SAMN04489747_1477   Auraticoccus monumenti MON 2.2 SDD66725.1    
 SAMN04489747_2022   Auraticoccus monumenti MON 2.2 SDD90304.1    
 SAMN04489747_2709   Auraticoccus monumenti MON 2.2 SDE17511.1    
 SAMN04489747_4133   Auraticoccus monumenti MON 2.2 SDE70461.1    
 SAMN04489747_0807   Auraticoccus monumenti MON 2.2 SDD36934.1    
 glycosyl hydrolase, family 3   Aureimonas altamirensis DSM 21988 BAT26447.1    
 glycosyl hydrolase, family 3   Aureimonas frigidaquae JCM 14755 BAT28978.1    
 M673_13815   Aureimonas sp. AU20 ALN73798.1    
 M673_11945   Aureimonas sp. AU20 ALN73430.1    
 dqs_0770   Azoarcus olearius DQS4 ANQ83845.1    
 dqs_1772   Azoarcus olearius DQS4 ANQ84814.1    
 azo0701   Azoarcus sp. BH72 CAL93318.1 A1K3B3  
 azo1647   Azoarcus sp. BH72 CAL94264.1 A1K609  
 AzCIB_2782   Azoarcus sp. CIB AKU12675.1    
 AZKH_2830   Azoarcus sp. KH32C BAL25132.1    
 AZC_1732   Azorhizobium caulinodans ORS 571 BAF87730.1 A8I4H5  
 ABAZ39_16685   Azospirillum brasilense Az39 AIB13574.1    
 AMK58_18660   Azospirillum brasilense Sp 7 ALJ37482.1    
 AMK58_16800   Azospirillum brasilense Sp 7 ALJ37157.1    
 AZOBR_p120114 (fragment)   Azospirillum brasilense Sp245 CCC99796.1    
 AZOBR_p120115 (fragment) (frameshift)   Azospirillum brasilense Sp245 CCC99797.1    
 AZOLI_p10769 (NagZ)   Azospirillum lipoferum 4B CBS88980.1    
 AZL_a04490 (NagZ)   Azospirillum sp. B510 BAI73980.1 D3P001  
 AZL_c03570 (short fragment)   Azospirillum sp. B510 BAI75650.1 D3P4S1  
 AL072_22550   Azospirillum thiophilum BV-S ALG73728.1    
 ACG10_05855   Azotobacter chroococcum B3 ASL25888.1    
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