Glycoside Hydrolase Family 3

Activities in Familyβ-glucosidase (EC 3.2.1.21); xylan 1,4-β-xylosidase (EC 3.2.1.37); β-glucosylceramidase (EC 3.2.1.45); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); glucan 1,3-β-glucosidase (EC 3.2.1.58); glucan 1,4-β-glucosidase (EC 3.2.1.74); isoprimeverose-producing oligoxyloglucan hydrolase (EC 3.2.1.120); coniferin β-glucosidase (EC 3.2.1.126); exo-1,3-1,4-glucanase (EC 3.2.1.-); β-N-acetylglucosaminide phosphorylases (EC 2.4.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseAsp (experimental);
Catalytic Proton DonorGlu for hydrolases (experimental); histidine for phosphorylases (experimental)
NoteA recent paper by Macdonald et al. (PMID=25533455) has shown that the enzymes that cleave b-hexosaminides are in fact retaining b-glycoside phosphorylases.
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX ;
Statistics GenBank accession (18266); Uniprot accession (2560); PDB accession (110); 3D entries (35); cryst (4)
All (17409) Archaea (95) Bacteria (16188) Eukaryota (1024) Viruses (1) unclassified (101) Structure (35 - 4 cryst) Characterized (296)
| 1 | ... | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | ... | 162 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ABLL_1750   Arcobacter sp. L BAK73625.1    
 LPB137_04795   Arcobacter sp. LPB0137 APW65207.1    
 CFX0092_b0832   Ardenticatena Cfx-K CUS06366.1    
 CFX0092_a2966   Ardenticatena Cfx-K CUS04844.1
CUS04862.2
   
 CFX0092_a0467   Ardenticatena Cfx-K CUS02348.1
CUS02359.2
   
 CFX0092_a1634 (BglB)   Ardenticatena Cfx-K CUS03512.1
CUS03526.2
   
 CFX0092_a1005 (BglX)   Ardenticatena Cfx-K CUS02883.1
CUS02893.2
   
 AREALGSMS7_03216   Arenibacter algicola SMS7 ASO06643.1    
 AREALGSMS7_02550   Arenibacter algicola SMS7 ASO05993.1    
 AREALGSMS7_03401   Arenibacter algicola SMS7 ASO06826.1    
 AREALGSMS7_01333 (BglB)   Arenibacter algicola SMS7 ASO04806.1    
 ebA5547 (NagZ)   Aromatoleum aromaticum EbN1 CAI09283.1 Q5P081  
 ADJ73_10560   Arsenicicoccus sp. oral taxon 190 F0371 AKT51629.1    
 ARN_29200 (NagZ)   Arsenophonus nasoniae CBA75455.1 D2U2U1  
 ARN_13140   Arsenophonus nasoniae CBA72620.1 D2TYT2  
 AS189_07555   Arthrobacter alpinus ERGS4:06 ALO66371.1    
 AS189_17220   Arthrobacter alpinus ERGS4:06 ALO67901.1    
 AS189_04165   Arthrobacter alpinus ERGS4:06 ALO65835.1    
 AS189_18505   Arthrobacter alpinus ERGS4:06 ALO68123.1    
 AS189_07330   Arthrobacter alpinus ERGS4:06 ALO68403.1    
 AOC05_10575   Arthrobacter alpinus R3.8 ALE94161.1    
 AOC05_00860   Arthrobacter alpinus R3.8 ALE91248.1    
 AOC05_02140   Arthrobacter alpinus R3.8 ALE93904.1    
 BN1051_02968 (BglX)   Arthrobacter saudimassiliensis 11W110_air CEA09596.1    
 BN1051_00677   Arthrobacter saudimassiliensis 11W110_air CEA07365.1    
 CGQ24_17415   Arthrobacter sp. 7749 ASN40603.1    
 CGQ24_02775   Arthrobacter sp. 7749 ASN38041.1    
 MB46_00235   Arthrobacter sp. A3 ALV44171.1    
 MB46_11115   Arthrobacter sp. A3 ALV45953.1    
 MB46_01680   Arthrobacter sp. A3 ALV47324.1    
 MB46_11305   Arthrobacter sp. A3 ALV47602.1    
 MB46_14520   Arthrobacter sp. A3 ALV46525.1    
 AUT26_13535   Arthrobacter sp. ATCC 21022 AMB42567.1    
 AUT26_02875   Arthrobacter sp. ATCC 21022 AMB39281.1    
 AUT26_02500   Arthrobacter sp. ATCC 21022 AMB39214.1    
 AL755_15970   Arthrobacter sp. ERGS1:01 ALE07895.1    
 AL755_02405   Arthrobacter sp. ERGS1:01 ALE04538.1    
 AL755_16835   Arthrobacter sp. ERGS1:01 ALE07930.1    
 AL755_21640   Arthrobacter sp. ERGS1:01 ALE07477.1    
 AL755_05360   Arthrobacter sp. ERGS1:01 ALE07584.1    
 AL755_01155   Arthrobacter sp. ERGS1:01 ALE04344.1    
 AL755_16165   Arthrobacter sp. ERGS1:01 ALE07901.1    
 AL755_02400   Arthrobacter sp. ERGS1:01 ALE04537.1    
 AL755_04145   Arthrobacter sp. ERGS1:01 ALE04880.1    
 Arth_0505   Arthrobacter sp. FB24 ABK01904.1 A0JS84  
 Arth_1839   Arthrobacter sp. FB24 ABK03229.1 A0JW09  
 Arth_2890   Arthrobacter sp. FB24 ABK04269.1 A0JYZ9  
 Arth_3149   Arthrobacter sp. FB24 ABK04527.1 A0JZQ7  
 AHiyo4_39180 (fragment)   Arthrobacter sp. Hiyo4 BAS10496.1    
 AHiyo4_05730   Arthrobacter sp. Hiyo4 BAS07151.1    
 AHiyo4_35440   Arthrobacter sp. Hiyo4 BAS10122.1    
 AHiyo4_39170 (fragment)   Arthrobacter sp. Hiyo4 BAS10495.1    
 AHiyo8_09020 (fragment)   Arthrobacter sp. Hiyo8 BAS12599.1    
 AHiyo8_54070 (fragment)   Arthrobacter sp. Hiyo8 BAS17104.1    
 AHiyo8_54060 (fragment)   Arthrobacter sp. Hiyo8 BAS17103.1    
 AHiyo8_39670   Arthrobacter sp. Hiyo8 BAS15664.1    
 AHiyo8_54050 (fragment)   Arthrobacter sp. Hiyo8 BAS17102.1    
 AHiyo8_09030 (fragment)   Arthrobacter sp. Hiyo8 BAS12600.1    
 AHiyo8_52450 (fragment)   Arthrobacter sp. Hiyo8 BAS16942.1    
 AHiyo8_30720 (fragment)   Arthrobacter sp. Hiyo8 BAS14769.1    
 AHiyo8_52460 (fragment)   Arthrobacter sp. Hiyo8 BAS16943.1    
 UM93_02520   Arthrobacter sp. IHBB 11108 AJT42817.1    
 UM93_07465   Arthrobacter sp. IHBB 11108 AJT42963.1    
 AFL94_04045   Arthrobacter sp. LS16 ALD63246.1    
 AFL94_01800   Arthrobacter sp. LS16 ALD62894.1    
 ART_3861   Arthrobacter sp. PAMC 25486 AIY03460.1    
 ART_0502   Arthrobacter sp. PAMC 25486 AIY00101.1    
 ART_1629   Arthrobacter sp. PAMC 25486 AIY01228.1    
 BWQ92_16920   Arthrobacter sp. QXT-31 APX04587.1    
 ARUE_c10900   Arthrobacter sp. Rue61a AFR28011.1    
 ARUE_c42180 (YbbD)   Arthrobacter sp. Rue61a AFR31090.1    
 ARUE_c20320   Arthrobacter sp. Rue61a AFR28937.1    
 ARUE_c06220   Arthrobacter sp. Rue61a AFR27557.1    
 ARUE_c18440 (Bglx1)   Arthrobacter sp. Rue61a AFR28750.1    
 ARUE_c18720 (Bglx2)   Arthrobacter sp. Rue61a AFR28778.1    
 ARUE_c28990 (NagZ)   Arthrobacter sp. Rue61a AFR29785.1    
 ARUE_c18700   Arthrobacter sp. Rue61a AFR28776.1    
 ASPU41_04865   Arthrobacter sp. U41 AOT02777.1    
 ATC04_16255   Arthrobacter sp. YC-RL1 ALQ31942.1    
 ATC04_13790 (fragment)   Arthrobacter sp. YC-RL1 ALQ31515.1    
 CGK93_22845   Arthrobacter sp. YN ASN22181.1    
 CGK93_05925   Arthrobacter sp. YN ASN19278.1    
 CGK93_15850   Arthrobacter sp. YN ASN20985.1    
 CGK93_02860   Arthrobacter sp. YN ASN18761.1    
 CGK93_03435   Arthrobacter sp. YN ASN18862.1    
 ARZXY2_3398   Arthrobacter sp. ZXY-2 AOY72912.1    
 ARZXY2_2865 (BglX)   Arthrobacter sp. ZXY-2 AOY72390.1    
 ARZXY2_3319 (BglX)   Arthrobacter sp. ZXY-2 AOY72833.1    
 ARZXY2_4524 (BglX) (fragment)   Arthrobacter sp. ZXY-2 AOY74023.1    
 ARZXY2_1518 (BglX)   Arthrobacter sp. ZXY-2 AOY71071.1    
 ARZXY2_4689 (BglX)   Arthrobacter sp. ZXY-2 AOY74188.1    
 ARZXY2_940   Arthrobacter sp. ZXY-2 AOY70501.1    
 NIES39_A02950   Arthrospira platensis NIES-39 BAI88134.1 D4ZXQ6  
 AP285_01165   Arthrospira platensis YZ AMW26811.1    
 ARTHRO_61029   Arthrospira sp. PCC 8005 CDM98428.1    
 Asbog_00768   Asaia bogorensis NBRC 16594 BAT19063.1    
 Astex_1219   Asticcacaulis excentricus CB 48 ADU12894.1 C5SPX4  
 Astex_1355   Asticcacaulis excentricus CB 48 ADU13025.1 C5SMQ9  
 Astex_1373   Asticcacaulis excentricus CB 48 ADU13043.1    
 Astex_1600   Asticcacaulis excentricus CB 48 ADU13266.1 C5SGS3  
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