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Polysaccharide Lyase Family 8

Activities in FamilyExo-β-1,4-glucuronan lyase (EC 4.2.2.-);
Exo-hyaluronate lyase (EC 4.2.2.-);
Hyaluronate lyase (EC 4.2.2.1);
Xanthan lyase (EC 4.2.2.12);
Chondroitinase B (EC 4.2.2.19);
Poly(β-mannuronate) lyase / M-specific alginate lyase (EC 4.2.2.3);
Chondroitin AC lyase (EC 4.2.2.5);
Heparin lyase / heparin lyase I (EC 4.2.2.7);
Mechanism b-elimination
3D Structure Status( α / α ) 6 toroid + anti-parallel β-sheet
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (4807); Uniprot accession (30); PDB accession (54); 3D entries (13); cryst (1)
Summary
Download PL8 (5166) Taxonomic display Structure (13 - 1 cryst) Characterized (33)
| 1 | ... | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 JOS67_00025   Vibrio diabolicus SLV18 QRG81493.1     2
 JOS67_00210   Vibrio diabolicus SLV18 QRG81525.1     2
 chondroitin ABC lyase   Vibrio hyugaensis LWW-1 QYO75062.1     2
 QYQ96_16390   Vibrio metoecus ZF102 WKY95432.1    
 AL543_05760   Vibrio mimicus FDAARGOS_112 AMG02626.1
AMG02626.2		    
 NP431_08800   Vibrio natriegens 14048 UUI10582.1    
 NP431_21575   Vibrio natriegens 14048 UUI13611.1    
 BA891_10495   Vibrio natriegens CCUG 16371 ANQ18533.1    
 BA891_06955   Vibrio natriegens CCUG 16371 ANQ16969.1    
 BA891_15430   Vibrio natriegens CCUG 16371 ANQ18607.1    
 BA893_09595   Vibrio natriegens CCUG 16373 ANQ21911.1    
 BA893_11240   Vibrio natriegens CCUG 16373 ANQ22212.1    
 BA893_16730   Vibrio natriegens CCUG 16373 ANQ23311.1    
 BA894_10915   Vibrio natriegens CCUG 16374 ANQ26929.1    
 BA894_18525   Vibrio natriegens CCUG 16374 ANQ28419.1    
 BA894_09185   Vibrio natriegens CCUG 16374 ANQ26616.1    
 U5A87_16555   Vibrio natriegens CL-2 WVE33393.1    
 U5A87_04840   Vibrio natriegens CL-2 WVE31752.1    
 PN96_04575   Vibrio natriegens NBRC 15636 = ATCC 14048 = DSM 759 ALR15287.1
ANQ12854.1		    
 PN96_15915   Vibrio natriegens NBRC 15636 = ATCC 14048 = DSM 759 ANQ14970.1
ALR17479.1		    
 VER99_18930   Vibrio natriegens NBRC 15636 = ATCC 14048 = DSM 759 WRS49979.1    
 VER99_08585   Vibrio natriegens NBRC 15636 = ATCC 14048 = DSM 759 WRS47467.1    
 OFO16_10460   Vibrio natriegens PWH3a UYI46267.1    
 I3X05_23340   Vibrio navarrensis 20-VB00237 QPL56579.1     2
 I3X05_23400   Vibrio navarrensis 20-VB00237 QPL56591.1     2
 I3X05_23395   Vibrio navarrensis 20-VB00237 QPL56590.1     2
 I3X05_23335   Vibrio navarrensis 20-VB00237 QPL56578.1     2
 VIBNI_B0676   Vibrio nigripulchritudo SFn1 CCO60476.1    
 VIBNI_A2386   Vibrio nigripulchritudo SFn1 CCO58454.1    
 VNTUMSATTG_42370   Vibrio nigripulchritudo TUMSAT-TG-2018 BCL72300.1    
 TUMSATVNIG1_42680   Vibrio nigripulchritudo TUMSAT-V.nig1 BDU33659.1    
 TUMSATVNIG2_41870   Vibrio nigripulchritudo TUMSAT-V.nig2 BDU39718.1    
 TUMSATVNIG3_42390   Vibrio nigripulchritudo TUMSAT-V.nig3 BDU45441.1    
 ACOMICROBIO_ LOCUS 4204   Vibrio sp. B1REV9 CAE6960398.1     2
 ACOMICROBIO_ LOCUS 4182   Vibrio sp. B1REV9 CAE6959995.1     2
 ACOMICROBIO_ LOCUS 4221   Vibrio sp. B1REV9 CAE6960632.1     2
 ACOMICROBIO_ LOCUS 4181   Vibrio sp. B1REV9 CAE6959986.1     2
 DBX26_21450   Vibrio sp. dhg AXT73501.1    
 DBX26_08700   Vibrio sp. dhg AXT71121.1    
 VEJY3_08795   Vibrio sp. EJY3 AEX22247.1    
 VEJY3_11250   Vibrio sp. EJY3 AEX22728.1    
 VEJY3_24021   Vibrio sp. EJY3 AEX25213.1    
 HCDase   Vibrio sp. FC509 ALJ56196.1     2
 hyaluronan/chondroitin sulphate lyase (HCLase) 4.2.2.1
4.2.2.5		 Vibrio sp. FC509 AUX13101.1    
 glycosaminoglycan lyase / eliminase (HCLase) 4.2.2.1
4.2.2.5		 Vibrio sp. FC509 AIL54323.1 A0A077ERI8  
 HCLaseV, partial   Vibrio sp. H240 UOI39494.1    
 glycosaminoglycan polysaccharide lyase, partial   Vibrio sp. QY108 QJQ82421.1    
 INR79_22115   Vibrio sp. SCSIO 43132 UAB73843.1    
 J4N45_19010   Vibrio sp. SCSIO 43140 USD63092.1    
 L0B53_14360   Vibrio sp. SS-MA-C1-2 UJF18192.1    
 VspSTUT11_07860   Vibrio sp. STUT-A11 BDR12810.1    
 VspSTUT11_33150   Vibrio sp. STUT-A11 BDR15339.1    
 IUZ65_005520   Vibrio sp. VB16 UGA55818.1    
 CEQ48_01545   Vibrio tarriae 2521-89 ASK53517.1    
 PVE41_18335   Vibrio vulnificus 1908-10 WHE24376.1    
 PVE41_18240   Vibrio vulnificus 1908-10 WHE24357.1    
 H6S61_20650   Vibrio vulnificus 2497-87 QNE02734.1    
 H6S61_20750   Vibrio vulnificus 2497-87 QNE02753.1    
 VV93_v1c44830   Vibrio vulnificus 93U204 AIL73534.1    
 VV93_v1c45010   Vibrio vulnificus 93U204 AIL73552.1    
 AL549_02255   Vibrio vulnificus ATL 6-1306 AMG10179.1    
 AL549_02160   Vibrio vulnificus ATL 6-1306 AMG10160.1    
 VV21090   Vibrio vulnificus CMCP6 AAO07996.1
NP_763006.1		    
 VV21110   Vibrio vulnificus CMCP6 AAO08015.1
NP_763025.1		    
 E2I22_18375   Vibrio vulnificus CMCP6 QBN16087.1    
 E2I22_18280   Vibrio vulnificus CMCP6 QBN16069.1    
 FORC17_4523   Vibrio vulnificus FORC_017 ANN29586.1    
 FORC17_4503   Vibrio vulnificus FORC_017 ANN29566.1    
 FORC36_4476   Vibrio vulnificus FORC_036 ARN68993.1    
 FORC36_4456   Vibrio vulnificus FORC_036 ARN68973.1    
 FORC37_4353   Vibrio vulnificus FORC_037 ASC60047.1    
 FORC37_4373   Vibrio vulnificus FORC_037 ASC60067.1    
 FORC77_4239   Vibrio vulnificus FORC_077 QBH29962.1    
 FORC77_4258   Vibrio vulnificus FORC_077 QBH29981.1    
 RI132_15235   Vibrio vulnificus GCU-01 WNJ72520.1    
 RI132_15330   Vibrio vulnificus GCU-01 WNJ72538.1    
 VVM_03164   Vibrio vulnificus MO6-24/O ADV89524.1    
 VVM_03115   Vibrio vulnificus MO6-24/O ADV89503.1    
 F6X00_23030   Vibrio vulnificus Vv180806 QMV39239.1    
 VV208B2_37880   Vibrio vulnificus VV20-8B-2 BDP32708.1    
 VV208B2_37690   Vibrio vulnificus VV20-8B-2 BDP32689.1    
 BWZ32_16660   Vibrio vulnificus VV2014DJH AUJ36485.1    
 QPX65_21410   Vibrio vulnificus VV2018 WIL76165.1    
 QPX65_21315   Vibrio vulnificus VV2018 WIL76146.1    
 VV0534   Vibrio vulnificus YJ016 BAC93298.1
NP_933327.1		    
 VVA1636   Vibrio vulnificus YJ016 BAC97662.1
NP_937692.1		    
 VVA1613   Vibrio vulnificus YJ016 BAC97639.1
NP_937669.1		    
 VV0533   Vibrio vulnificus YJ016 BAC93297.1
NP_933326.1		    
 G5S32_08405   Vibrio ziniensis ZWAL4003 QIH42011.1    
 NF212_21065   Vibrionaceae bacterium SE-01 WWE61867.1    
 C5Q97_13800   Victivallales bacterium CCUG 44730 AVM45714.1    
 C5Q97_06605   Victivallales bacterium CCUG 44730 AVM44401.1    
 C5Q97_12785   Victivallales bacterium CCUG 44730 AVM45527.1    
 QNH47_01495   Virgibacillus halodenitrificans ACCC02857 WHX26556.1    
 QNH47_19070   Virgibacillus halodenitrificans ACCC02857 WHX26206.1     2
 BME96_15890   Virgibacillus halodenitrificans PDB-F2 APC49583.1     2
 AXE80_10005   Wenyingzhuangia fucanilytica CZ1127 ANW96592.1    
 ORF62   Yersinia enterocolitica 29854 CAP20152.1    
 LI89_22280   Yersinia enterocolitica FORC-002 ALG47349.1    
 FORC2_p069   Yersinia enterocolitica FORC_002 AKF40347.1    
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