Activities in Family	Exo-β-1,4-glucuronan lyase (EC 4.2.2.-); Exo-hyaluronate lyase (EC 4.2.2.-); Hyaluronate lyase (EC 4.2.2.1); Xanthan lyase (EC 4.2.2.12); Chondroitinase B (EC 4.2.2.19); Poly(β-mannuronate) lyase / M-specific alginate lyase (EC 4.2.2.3); Chondroitin AC lyase (EC 4.2.2.5); Heparin lyase / heparin lyase I (EC 4.2.2.7);
Mechanism	b-elimination
3D Structure Status	( α / α ) 6 toroid + anti-parallel β-sheet
Commercial Enzyme Provider(s)	MEGAZYME; PROZOMIX;
Statistics	GenBank accession (4807); Uniprot accession (30); PDB accession (54); 3D entries (13); cryst (1)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
P8A20_34965		Streptomyces sp. Alt3	WLQ68447.1
P8A20_05095		Streptomyces sp. Alt3	WLQ63012.1			2
P0D76_28330		Streptomyces sp. AM 3-1-1	WEH30924.1
RPQ07_10825		Streptomyces sp. AM2-3-1	WNO77129.1
RPQ02_33370		Streptomyces sp. AM8-1-1	WNO68364.1
RPQ02_35905		Streptomyces sp. AM8-1-1	WNO68823.1
RPQ02_33710		Streptomyces sp. AM8-1-1	WNO68426.1
RPQ02_33715		Streptomyces sp. AM8-1-1	WNO68427.1
RPQ02_06100		Streptomyces sp. AM8-1-1	WNO63397.1
RPQ02_02840		Streptomyces sp. AM8-1-1	WNO62810.1
CVT30_11625		Streptomyces sp. AMCC400023	UJV40422.1
M6G09_25545		Streptomyces sp. B146	WGK48687.1
RI578_11750		Streptomyces sp. BB1-1-1	WND34911.1
RI578_38465		Streptomyces sp. BB1-1-1	WND39819.1
K2224_13570		Streptomyces sp. BHT-5-2	QZL04100.1
WAB15_28820		Streptomyces sp. BP-8	WXK79687.1
OH540_11395		Streptomyces sp. BPPL-273	WHM30605.1
QIY60_05280		Streptomyces sp. BPTC-684	WHM41211.1
QIY60_29170		Streptomyces sp. BPTC-684	WHM40538.1
JIX56_12590		Streptomyces sp. CA-210063	UUU30674.1
JHY03_67320		Streptomyces sp. CA-256286	QTA36517.1
N7925_00745		Streptomyces sp. CA-278952	WDG26959.1
N7925_34785		Streptomyces sp. CA-278952	WDG33135.1
HYC88_34760		Streptomyces sp. CB00271	QNQ38369.1
HXS80_00535		Streptomyces sp. CB04723	QLG30295.1
C4J65_24690		Streptomyces sp. CB09001	AXL93470.1
L6J92_08095		Streptomyces sp. CB09030	UOG79162.1
hyaluronidase, partial (Hyal16-3)		Streptomyces sp. CB16	ASB17095.1
NI25_11545		Streptomyces sp. CCM_MD2014	AIV34038.1
AS200_15735		Streptomyces sp. CdTB01	ALV33316.1
ABE83_00480		Streptomyces sp. CFMR 7	ALC25730.1
RJD14_22780		Streptomyces sp. CGMCC 4.1456	WNF65239.1
VJ737_12310		Streptomyces sp. CGMCC 4.1772	WRT98415.1
CAC01_03330		Streptomyces sp. CLI2509 CLI2905	ASY31840.1
CXR04_10615		Streptomyces sp. CMB-StM0423	AUH40639.1
CXR04_19610		Streptomyces sp. CMB-StM0423	AUH42115.1
AA958_33990		Streptomyces sp. CNQ-509	AKH86416.1
AA958_14650		Streptomyces sp. CNQ-509	AKH83261.1
AA958_24125		Streptomyces sp. CNQ-509	AKH84788.1
AA958_33960		Streptomyces sp. CNQ-509	AKH86410.1
NNW99_09975		Streptomyces sp. CRCS-T-1	UUA18880.1
NNW98_09975		Streptomyces sp. CRLD-Y-1	UUA11279.1
JIX55_35455		Streptomyces sp. DSM 40750	UUU25132.1
HB370_27990		Streptomyces sp. DSM 40868	QIS73355.1
HB370_35970		Streptomyces sp. DSM 40868	QIS74723.1
EASAB2608_05028		Streptomyces sp. EAS-AB2608 NBRC 114648	BCM69694.1
WID27_00255		Streptomyces sp. f41	WYH73916.1
KK483_34060		Streptomyces sp. FIT100	UUN30803.1
KK483_09650		Streptomyces sp. FIT100	UUN26647.1
KK483_33030		Streptomyces sp. FIT100	UUN30624.1
KK483_01320		Streptomyces sp. FIT100	UUN30967.1
KK483_01905		Streptomyces sp. FIT100	UUN25305.1
KK483_27955		Streptomyces sp. FIT100	UUN29784.1
KK483_03945		Streptomyces sp. FIT100	UUN25667.1
KK483_09655		Streptomyces sp. FIT100	UUN26648.1
KK483_27990		Streptomyces sp. FIT100	UUN29790.1
Q7C01_08055		Streptomyces sp. FXY-T5	WMD04352.1
NUT86_28975		Streptomyces sp. G7(2002)	WDT57755.1
KQY30_09550		Streptomyces sp. GMY02	QXE39009.1
C1703_28055 (XlY)		Streptomyces sp. Go-475	AXE88876.1
KBP30_13220		Streptomyces sp. Go40/10 Go 40/10	UFR02086.1
GR130_31930		Streptomyces sp. GS7	QHC25301.1
LUV23_05485		Streptomyces sp. HNM0561	UHH15841.1
LUV23_44580		Streptomyces sp. HNM0561	UHH22783.1
MQE23_13540		Streptomyces sp. HP-A2021	UOB10022.1
M1P56_26885		Streptomyces sp. HU2014	UQI47707.1
N8I86_26775		Streptomyces sp. HUAS 14-6	UXY38024.1
N8I87_28705		Streptomyces sp. HUAS 15-9	UXY30141.1
O1G22_12885		Streptomyces sp. HUAS 2-6	WBO63658.1
PGH47_30125		Streptomyces sp. HUAS 31	WCD99698.1
QRN89_24785		Streptomyces sp. HUAS CB01	WJY52746.1
Q3Y68_10520		Streptomyces sp. HUAS CX7	WKX23373.1
R2D22_00795		Streptomyces sp. HUAS YS2	WOX20010.1
R2D22_10985		Streptomyces sp. HUAS YS2	WOX26607.1
DRB96_38510		Streptomyces sp. ICC1	AWZ17080.1
DRB89_38035		Streptomyces sp. ICC4	AWZ09313.1
G7Z12_10535		Streptomyces sp. ID38640	QIK06408.1
RLT58_03605		Streptomyces sp. ITFR-16	WNI21065.1
RLT58_10020		Streptomyces sp. ITFR-16	WNI26854.1
RLT58_33445		Streptomyces sp. ITFR-16	WNI26489.1
RLT59_09610		Streptomyces sp. ITFR-6	WNI34015.1
RLT59_37095		Streptomyces sp. ITFR-6	WNI33793.1
RLT59_03260		Streptomyces sp. ITFR-6	WNI27892.1
G7Z13_24910		Streptomyces sp. JB150	QIJ66747.1
PPN52_32905		Streptomyces sp. JCM 35825	WCL89011.1
PPN52_29795		Streptomyces sp. JCM 35825	WCL90023.1
NOO62_28430		Streptomyces sp. Je 1-369	WAL98069.1
NOO62_31380		Streptomyces sp. Je 1-369	WAL98596.1
SLV14_002298		Streptomyces sp. Je 1-4	UYB39758.1
NEH83_01030		Streptomyces sp. JUS-F4	WKN12903.1
NEH83_36270		Streptomyces sp. JUS-F4	WKN19167.1
R9806_08050		Streptomyces sp. KN37	WPO70579.1
R9806_03895		Streptomyces sp. KN37	WPO69834.1
D1J63_10405		Streptomyces sp. KPB2	AZM80021.1
DKB27_08110		Streptomyces sp. KY2	QNF55055.1
STKY70_0093		Streptomyces sp. KY70	CAD5912527.1
STKY75_7477		Streptomyces sp. KY75	CAD5994916.1
F3K22_31120		Streptomyces sp. LBUM 1475	QTU64860.1
F3K21_30545		Streptomyces sp. LBUM 1480	QTU56591.1
F3K20_31755		Streptomyces sp. LBUM 1482	QTU48773.1
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