Known Activities	hyaluronate lyase (EC 4.2.2.1); chondroitin AC lyase (EC 4.2.2.5); xanthan lyase (EC 4.2.2.12); chondroitin ABC lyase (EC 4.2.2.20)
3D Structure Status	( α / α ) 6 barrel + anti-parallel β-sheet
External resources	InterPro; PFAM;
Commercial Enzyme Provider(s)	MEGAZYME; PROZOMIX;
Statistics	GenBank accession (361); Uniprot accession (191); PDB accession (44); 3D entries (9); cryst (1)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
chondroitin AC lyase	4.2.2.1 4.2.2.5	Arthrobacter aurescens		P84141	1RW9[A] 1RWA[A] 1RWC[A] 1RWF[A] 1RWG[A] 1RWH[A]
xanthan lyase (Xly)	4.2.2.12	Bacillus sp. GL1	BAB21059.1	Q9AQS0	1J0M[A] 1J0N[A] 1X1H[A] 1X1I[A] 1X1J[A] 2E22[A] 2E24[A]
chondroitin sulfate ABC lyase	4.2.2.20	Bacteroides thetaiotaomicron WAL2926	ABV21364.1	C5G6D7	2Q1F[A,B]	2
chondroitin AC lyase (CslA;ChnAC;Phep_0786)	4.2.2.5	Pedobacter heparinus DSM 2366	AAC83383.1 ACU03008.1	Q59288	1CB8[A] 1HM2[A] 1HM3[A] 1HMU[A] 1HMW[A]	3
chondroitin ABC lyase I	4.2.2.20	Proteus vulgaris	2109195A ABE23097.1 ACN04689.1 ACQ12496.1 ACQ12497.1 ACW17440.1 ACW17441.1 ACY01450.1	P59807	1HN0[A]	2
chondroitin ABC lyase II (ChABCII)	4.2.2.20	Proteus vulgaris ATCC 6896	AAB43333.1 ABU46331.1		cryst	2
hyaluronate lyase	4.2.2.1	Streptococcus agalactiae TYPE III / GBS 3502	AAA56749.1	Q53591	1F1S[A] 1I8Q[A] 1LXM[A]	1
hyaluronate lyase (HysA)	4.2.2.1	Streptococcus pneumoniae R6	AAA53685.1 AAA53686.1 AAK99090.1 AAT16666.1 ACK14456.1 ACW45175.1 NP_357880.1	Q8CWU3	1C82[A] 1EGU[A] 1F9G[A] 1LOH[A] 1LXK[A] 1N7N[A] 1N7O[A] 1N7P[A] 1N7Q[A] 1N7R[A] 1OJM[A] 1OJN[A] 1OJO[A] 1OJP[A] 1W3Y[A] 2BRP[A] 2BRV[X] 2BRW[A,B]	1
hyaluronate lyase (PL8Hyal;SCO5534;SC1C2.15)	4.2.2.1	Streptomyces coelicolor A3(2)	CAA19982.1 NP_629668.1	O86516	2WCO[A] 2WDA[A] 2X03[A,B]

Last update: 2012-01-31 © Copyright 1998-2012
AFMB - CNRS - Universités Aix-Marseille I & II