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Polysaccharide Lyase Family 8

Activities in FamilyExo-β-1,4-glucuronan lyase (EC 4.2.2.-);
Exo-hyaluronate lyase (EC 4.2.2.-);
Hyaluronate lyase (EC 4.2.2.1);
Xanthan lyase (EC 4.2.2.12);
Chondroitinase B (EC 4.2.2.19);
Poly(β-mannuronate) lyase / M-specific alginate lyase (EC 4.2.2.3);
Chondroitin AC lyase (EC 4.2.2.5);
Heparin lyase / heparin lyase I (EC 4.2.2.7);
Mechanism b-elimination
3D Structure Status( α / α ) 6 toroid + anti-parallel β-sheet
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (4807); Uniprot accession (30); PDB accession (54); 3D entries (13); cryst (1)
Summary
Download PL8 (5166) Taxonomic display Structure (13 - 1 cryst) Characterized (33)
| 1 | ... | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | ... | 47 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 K8227_05835 (fragment)   Streptococcus suis SZ1908 UAM75193.1     1
 NLY75_03910 (HylA)   Streptococcus suis T15 UTI57938.1     1
 T15_0747   Streptococcus suis T15 AGZ22850.1     1
 K6967_05585 (fragment)   Streptococcus suis Transconjugant cAKJ18 QZT30647.1     1
 K6967_05580 (fragment)   Streptococcus suis Transconjugant cAKJ18 QZT30646.1     1
 K6971_05575 (fragment)   Streptococcus suis Transconjugant cDY107 QZT24479.1     1
 K6971_05580 (fragment)   Streptococcus suis Transconjugant cDY107 QZT24480.1     1
 K6970_05555 (fragment)   Streptococcus suis Transconjugant cFJSM5 QZT20710.1     1
 K6970_05550 (fragment)   Streptococcus suis Transconjugant cFJSM5 QZT20709.1     1
 K6968_05595 (fragment)   Streptococcus suis Transconjugant cNJ3 QZT18812.1     1
 K6968_05600 (fragment)   Streptococcus suis Transconjugant cNJ3 QZT18813.1     1
 NOV96_04615 (HylA)   Streptococcus suis WUSS030 UYZ67136.1     1
 YB51_6050   Streptococcus suis YB51 AGW87582.1     1
 I5W22_05625 (fragment)   Streptococcus suis YP20190405 QPO27843.1     1
 I5W22_05630 (fragment)   Streptococcus suis YP20190405 QPO27844.1     1
 ZY05719_05815 (fragment)   Streptococcus suis ZY05719 AKG40504.1     1
 ZY05719_05810 (fragment)   Streptococcus suis ZY05719 AKG40503.1     1
 NCTC3858_01491 (HylB)   Streptococcus uberis NCTC3858 SQG46732.1     1
 NCTC13766_00113 (Hylb_2) (fragment)   Streptococcus urinalis NCTC13766 VEF31048.1     1
 NCTC13766_00112 (Hylb_1) (fragment)   Streptococcus urinalis NCTC13766 VEF31047.1     1
 DMT42_10045   Streptomyces actuosus ATCC 25421 AWT42623.1    
 K1J60_13055   Streptomyces akebiae MG28 QYX77329.1    
 SMD11_2031   Streptomyces albireticuli SMD11 ARZ67683.1    
 SMD44_01144   Streptomyces alboflavus MDJK44 ARX81746.1    
 SMD44_08331   Streptomyces alboflavus MDJK44 ARX88844.1    
 CP975_28655   Streptomyces alboniger ATCC 12461 QEV20991.1    
 CP975_31340   Streptomyces alboniger ATCC 12461 QEV21438.1    
 N1H47_27090   Streptomyces albulus IFO14147 UWS74592.1    
 DC74_5664   Streptomyces albulus NK660 AIA06116.1    
 SLNHY_4652   Streptomyces albus BK3-25 AOU79343.1    
 G3260_006570   Streptomyces albus CAS922 QID39655.1    
 NR995_01100   Streptomyces albus DSM 40763 UVN53260.1    
 NR995_05330   Streptomyces albus DSM 40763 UVN54014.1    
 SLNWT_4661   Streptomyces albus DSM 41398 AJE85037.1    
 DUI70_4572   Streptomyces albus ZD11 AYN35070.1    
 H9W91_29605   Streptomyces alfalfae XN-04 QUI34546.1    
 SAM23877_5289   Streptomyces ambofaciens ATCC 23877 AKZ58334.1    
 SAM40697_4788   Streptomyces ambofaciens DSM 40697 ANB08745.1    
 K7396_10630   Streptomyces angustmyceticus JCM 4053 UAL66934.1    
 QR300_39085   Streptomyces antimycoticus FIM95-F1 WJE02444.1    
 QR300_41865 (fragment)   Streptomyces antimycoticus FIM95-F1 WJE01939.1    
 QPM16_36840   Streptomyces anulatus K-31 WIY80646.1    
 QPM16_00750   Streptomyces anulatus K-31 WIY74367.1    
 OG771_01800   Streptomyces anulatus NBC_01421 WUY02396.1    
 OG771_38515   Streptomyces anulatus NBC_01421 WUY09128.1    
 KZO11_00745   Streptomyces anulatus VUW1 QYA92332.1    
 KZO11_37140   Streptomyces anulatus VUW1 QYA98794.1    
 HKX69_09970   Streptomyces argyrophyllae Jing01 QJS09806.1    
 DVA86_23225   Streptomyces armeniacus ATCC 15676 AXK35125.1    
 CD934_09335   Streptomyces asterosporus DSM 41452 QDI68864.1    
 P6B95_38345   Streptomyces atratus MJM3502 WPW32662.1    
 P6B95_32370   Streptomyces atratus MJM3502 WPW31628.1    
 P6B95_05775   Streptomyces atratus MJM3502 WPW26959.1    
 C5746_29510   Streptomyces atratus SCSIO_ZH16 AXE83106.1    
 C5746_36050   Streptomyces atratus SCSIO_ZH16 AXE81470.1    
 C5746_03170   Streptomyces atratus SCSIO_ZH16 AXE82565.1    
 O1Q96_36360   Streptomyces aurantiacus Qhu-M197 WAU84686.1    
 SU9_024925   Streptomyces auratus AGR0001 QTZ94291.1    
 G3H79_01710   Streptomyces aureoverticillatus HN6 QIB41984.1    
 G3H79_33140   Streptomyces aureoverticillatus HN6 QIB47213.1    
 BV401_05635   Streptomyces autolyticus CGMCC0516 AQA10055.1    
 SAV2704   Streptomyces avermitilis MA-4680 = NBRC 14893 BAC70415.1
NP_823880.1		    
 SAVMC3_31410   Streptomyces avermitilis MC3 BBJ50512.1    
 G4Z16_20195   Streptomyces bathyalis LN3S51 QPP08332.1    
 SBI_01112   Streptomyces bingchenggensis BCW-1 ADI04233.1    
 GQF42_39675   Streptomyces broussonetiae T44 QHA08576.1    
 GQF42_30420   Streptomyces broussonetiae T44 QHA07041.1    
 EJC51_33905   Streptomyces brunneus CR22 AZP20629.1    
 EJC51_41950   Streptomyces brunneus CR22 AZP22084.1    
 H7H31_29120   Streptomyces buecherae AC541 QNJ43297.1     2
 I6J39_33470   Streptomyces californicus FDAARGOS_1209 QRV31722.1    
 I6J40_00540   Streptomyces californicus FDAARGOS_1210 QRV52819.1    
 I6J41_33410   Streptomyces californicus FDAARGOS_1211 QRV45138.1    
 I6J42_00610   Streptomyces californicus FDAARGOS_1212 QRV32668.1    
 I6J43_33035   Streptomyces californicus FDAARGOS_1213 QRV51828.1    
 IHE65_12565   Streptomyces caniscabiei ID-03-3A WEO23940.1    
 OG925_16405   Streptomyces canus NBC_01585 WSD85778.1    
 N0X72_13355   Streptomyces carpaticus SCPM-O-B-9993 UWM49918.1    
 CVT27_32625   Streptomyces cavourensis 1AS2a ATY99735.1    
 NLU04_16470   Streptomyces cavourensis F2 UTR79954.1    
 OUQ49_32905   Streptomyces cavourensis NA4 WAE70200.1    
 DTW94_32760   Streptomyces cavourensis TJ430 AXI75564.1    
 NRO40_21400   Streptomyces changanensis HL-66 UUS34947.1    
 CP983_12950   Streptomyces chartreusis ATCC 14922 QEV67493.1    
 HUT05_14690   Streptomyces chartreusis NA02069 QKZ18502.1    
 CP977_33110   Streptomyces cinereoruber ATCC 19740 QEV36420.1    
 STRCI_005716   Streptomyces cinnabarinus DSM 40467 WAZ24312.1    
 STRCI_007476   Streptomyces cinnabarinus DSM 40467 WAZ25944.1    
 CRV15_06155   Streptomyces clavuligerus ATCC 27064 QCS05228.1    
 LL058_21695   Streptomyces clavuligerus DSM 738 WDN54246.1    
 D1794_06735   Streptomyces clavuligerus F1D-5 AXU12446.1    
 I3J04_06520   Streptomyces clavuligerus F1D1 QPL62538.1    
 I3J07_06575   Streptomyces clavuligerus F1D10 QPL80675.1    
 I3J08_21525   Streptomyces clavuligerus F1D14 QPL89485.1    
 I3J09_06535   Streptomyces clavuligerus F1D18 QPL98642.1    
 I3J16_06540   Streptomyces clavuligerus F1D26 QPM04659.1    
 I3J19_06520   Streptomyces clavuligerus F1D28 QPM22956.1    
 I3J17_21545   Streptomyces clavuligerus F1D31 QPM13351.1    
 I3J18_06555   Streptomyces clavuligerus F1D35 QPM16713.1    
 I3J05_06535   Streptomyces clavuligerus F1D4 QPL68570.1    
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