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Polysaccharide Lyase Family 8

Activities in FamilyExo-β-1,4-glucuronan lyase (EC 4.2.2.-);
Exo-hyaluronate lyase (EC 4.2.2.-);
Hyaluronate lyase (EC 4.2.2.1);
Xanthan lyase (EC 4.2.2.12);
Chondroitinase B (EC 4.2.2.19);
Poly(β-mannuronate) lyase / M-specific alginate lyase (EC 4.2.2.3);
Chondroitin AC lyase (EC 4.2.2.5);
Heparin lyase / heparin lyase I (EC 4.2.2.7);
Mechanism b-elimination
3D Structure Status( α / α ) 6 toroid + anti-parallel β-sheet
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (4807); Uniprot accession (30); PDB accession (54); 3D entries (13); cryst (1)
Summary
Download PL8 (5166) Taxonomic display Structure (13 - 1 cryst) Characterized (33)
| 1 | ... | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | ... | 47 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 AXK13_04410   Streptococcus pyogenes STAB13021 AND04811.1     1
 D8S76_04255   Streptococcus pyogenes TSPY155 QAX76081.1     1
 EB817_05445   Streptococcus pyogenes TSPY165 QAX71255.1     1
 EB818_03995   Streptococcus pyogenes TSPY208 QAX72693.1     1
 EB816_04290   Streptococcus pyogenes TSPY453 QAX69179.1     1
 D8S77_05490   Streptococcus pyogenes TSPY556 QAX74609.1     1
 GUT183_06600 (HysA)   Streptococcus ruminantium GUT-183 BDD38422.1     1
 GUT184_13790 (HysA)   Streptococcus ruminantium GUT-184 BDD41115.1     1
 GUT189_06120 (HysA)   Streptococcus ruminantium GUT-189 BDD42279.1     1
 SR187_3375   Streptococcus ruminantium GUT187T BBA92284.1     1
 BZG42_03485   Streptococcus sp. DAT741 QHF54467.1     1
 EGX96_00365   Streptococcus sp. FDAARGOS_520 AYZ03772.1     1
 EGX72_05860   Streptococcus sp. FDAARGOS_521 AYY68524.1     1
 EGX70_01505   Streptococcus sp. FDAARGOS_522 AYY63625.1     1
 A6J68_07690   Streptococcus sp. group B FDAARGOS_229 ARC25048.1     1
 NCTC10228_00503 (HylB)   Streptococcus sp. NCTC 10228 VUC96290.1     1
 NCTC11567_01447 (HylB)   Streptococcus sp. NCTC 11567 VUC99377.1     1
 H8787_02285   Streptococcus sp. NSJ-72 QNL42711.1     1
 J5M87_09090   Streptococcus sp. zg-86 QTH47675.1     1
 hyaluronidase (HylA)   Streptococcus suis CAG27053.1     1
 hyaluronidase (HylA)   Streptococcus suis CAG27052.1     1
 HylA (fragment)   Streptococcus suis CAC87664.1
ADF49630.1		     1
 hyaluronidase (HylA) (fragment)   Streptococcus suis CAG27068.1     1
 HAS68_04750   Streptococcus suis 05HAS68 AHF59038.1     1
 SSU05_1215 + SSU05_1214 (fragment)   Streptococcus suis 05ZYH33 ABP90180.1
ABP90181.1		     1
 hyaluronate lyase (HylA)   Streptococcus suis 1043248 AKC34794.1     1
 hyaluronate lyase (HylA)   Streptococcus suis 1097205 AKC34795.1     1
 ID09_06430   Streptococcus suis 6407 AIG43680.1     1
 AN924_01090   Streptococcus suis 90-1330 AMU78672.1     1
 hyaluronidase (HylA) (fragment)   Streptococcus suis 98015 ABD74496.1     1
 SSU98_1230 + SSU98_1229 (fragment)   Streptococcus suis 98HAH33 ABP92387.1
ABP92388.1		     1
 SSUA7_1065 (fragment)   Streptococcus suis A7 AER44387.1     1
 SSUA7_1066 (fragment)   Streptococcus suis A7 AER44388.1     1
 CR541_06040 (fragment)   Streptococcus suis CS100322 AUW24078.1     1
 CR541_06045 (fragment)   Streptococcus suis CS100322 AUW24079.1     1
 hyaluronidase (HylA) (fragment)   Streptococcus suis CVCC606 ABP35951.1     1
 hyaluronidase (HylA) (fragment)   Streptococcus suis CVCC607 ABP35952.1     1
 SSUD9_1371   Streptococcus suis D9 AER17555.1     1
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis DAT229 AKC34791.1     1
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis DAT261 AKC34790.1     1
 DAT299_07090 (HysA)   Streptococcus suis DAT299 BCK43145.1     1
 A6M16_03715   Streptococcus suis DN13 ANC99638.1     1
 JZ789_04940   Streptococcus suis GX69 UCS85665.1     1
 BFP66_03605   Streptococcus suis GZ0565 AOM74360.1     1
 SSGZ1_1070 (fragment)   Streptococcus suis GZ1 ADE31527.1     1
 SSGZ1_1071 (fragment)   Streptococcus suis GZ1 ADE31528.1     1
 CR542_06845   Streptococcus suis HA0609 AUW26221.1     1
 hyaluronidase   Streptococcus suis HA1001111 ADO66679.1     1
 hyaluronidase   Streptococcus suis HA1001112 ADO66680.1     1
 hyaluronidase (HylA) (fragment)   Streptococcus suis HA9801 ADC54170.1    
 FPT06_00400   Streptococcus suis INT-01 QDS22866.1     1
 DK235_05820 (fragment)   Streptococcus suis ISU1606 QLL45367.1     1
 DK235_05815 (fragment)   Streptococcus suis ISU1606 QLL45366.1     1
 DK877_05140   Streptococcus suis ISU2414 QLL53313.1     1
 DK875_06350   Streptococcus suis ISU2514 QLL49493.1     1
 DK237_06380   Streptococcus suis ISU2614 QLL47460.1     1
 DK878_06770   Streptococcus suis ISU2660 QLL55715.1     1
 DK876_05815 (fragment)   Streptococcus suis ISU2714 QLL51519.1     1
 DK876_05810 (fragment)   Streptococcus suis ISU2714 QLL51518.1     1
 hyaluronidase (HylA) (fragment)   Streptococcus suis JR0507 ADF49631.1    
 SSUJS14_1182 + SSUJS14_1181 (fragment)   Streptococcus suis JS14 ADV70253.1
ADV70254.1		     1
 A9494_05630 (fragment)   Streptococcus suis LSM102 ARX90495.1     1
 A9494_05625 (fragment)   Streptococcus suis LSM102 ARX90494.1     1
 GRI05_03655 (fragment)   Streptococcus suis LSM178 QOJ56825.1     1
 GRI05_03660 (fragment)   Streptococcus suis LSM178 QOJ56826.1     1
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis MGGUS2 AKC34789.1     1
 hyaluronate lyase (HylA)   Streptococcus suis MGGUS5 AKC34796.1     1
 hyaluronate lyase (HylA)   Streptococcus suis MGGUS9 AKC34799.1     1
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis MNCM01 AKC34787.1     1
 hyaluronate lyase (HylA)   Streptococcus suis MNCM04 AKC34797.1     1
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis MNCM16 AKC34788.1     1
 hyaluronate lyase (HylA)   Streptococcus suis MNCM43 AKC34798.1     1
 NCTC10234_01050 (fragment)   Streptococcus suis NCTC10234 SQH00684.1     1
 NCTC10237_01202   Streptococcus suis NCTC10237 VTT03533.1     1
 AA105_07005   Streptococcus suis NSUI002 ALA28993.1     1
 APQ97_06125   Streptococcus suis NSUI060 AML46650.1     1
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis P1/7 AKC34785.1     1
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis P477/03P1 AKC34793.1     1
 HylA 4.2.2.1 Streptococcus suis P5/11/88 CAC87663.1 Q8VLQ7   1
 hyaluronate lyase (HylA) (fragment)   Streptococcus suis P517/03P4 AKC34792.1     1
 YYK_05005 (HylA) (fragment)   Streptococcus suis S735 AFR00520.1
AKC34786.1		     1
 NJAUSS_1122 (fragment)   Streptococcus suis SC070731 AGG64591.1     1
 NJAUSS_1123 (fragment)   Streptococcus suis SC070731 AGG64592.1    
 hyaluronidase (HylA) (fragment)   Streptococcus suis SC152 ABD74495.1     1
 hyaluronidase (HylA) (fragment)   Streptococcus suis SC17 ABD74493.1     1
 JZY07_03870   Streptococcus suis SC183 QSQ91656.1     1
 B9H01_05865 (fragment)   Streptococcus suis SC19 ARL70058.1     1
 B9H01_05870 (fragment)   Streptococcus suis SC19 ARL70059.1     1
 hyaluronidase (HylA) (fragment)   Streptococcus suis SC22 ABD74494.1     1
 hyaluronidase (HylA)   Streptococcus suis SEROTYPE 2 CAG27049.1
CAG27048.1		     1
 hyaluronidase (HylA)   Streptococcus suis SEROTYPE 2 CAG27050.1     1
 hyaluronidase (HylA) 4.2.2.1 Streptococcus suis SEROTYPE 7 CAC87662.1 Q8VLQ8   1
 A7J08_03850   Streptococcus suis SRD478 ASW49450.1     1
 SSU12_1118 (fragment)   Streptococcus suis SS12 AER15299.1     1
 BVD85_05705 (fragment)   Streptococcus suis SS2-1 AUW22057.1     1
 BVD85_05700 (fragment)   Streptococcus suis SS2-1 AUW22056.1     1
 hyaluronidase (HylA) (fragment)   Streptococcus suis SS2-1 ADC54171.1    
 SSUST1_0748   Streptococcus suis ST1 AER21132.1     1
 SSUST3_1226   Streptococcus suis ST3 AEB81651.1     1
 K8227_05840 (fragment)   Streptococcus suis SZ1908 UAM75194.1     1
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