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Polysaccharide Lyase Family 8

Activities in FamilyExo-β-1,4-glucuronan lyase (EC 4.2.2.-);
Exo-hyaluronate lyase (EC 4.2.2.-);
Hyaluronate lyase (EC 4.2.2.1);
Xanthan lyase (EC 4.2.2.12);
Chondroitinase B (EC 4.2.2.19);
Poly(β-mannuronate) lyase / M-specific alginate lyase (EC 4.2.2.3);
Chondroitin AC lyase (EC 4.2.2.5);
Heparin lyase / heparin lyase I (EC 4.2.2.7);
Mechanism b-elimination
3D Structure Status( α / α ) 6 toroid + anti-parallel β-sheet
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (4733); Uniprot accession (30); PDB accession (54); 3D entries (13); cryst (1)
Summary
Download PL8 (5091) Taxonomic display Structure (13 - 1 cryst) Characterized (33)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 46 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 IAD21_04889 (CslA)   Abditibacteriota bacterium IAD-21 BCM93003.1    
 IAD21_02594 (XlY)   Abditibacteriota bacterium IAD-21 BCM90734.1    
 NYE86_18480   Actinacidiphila bryophytorum DS3 UWE10511.1    
 NYE86_19940   Actinacidiphila bryophytorum DS3 UWE10761.1    
 EF847_08160   Actinobacteria bacterium YIM 96077 AYY12689.1    
 Asera_63340   Actinocatenispora sera NBRC 101916 BCJ32226.1    
 Athai_66290   Actinocatenispora thailandica NBRC 105041 BCJ39126.1    
 Athai_61400   Actinocatenispora thailandica NBRC 105041 BCJ38637.1    
 Athai_09720   Actinocatenispora thailandica NBRC 105041 BCJ33469.1    
 Athai_37990   Actinocatenispora thailandica NBRC 105041 BCJ36296.1    
 Athai_07180   Actinocatenispora thailandica NBRC 105041 BCJ33215.1    
 BKM31_31155   [Actinomadura] parvosata subsp. kistnae ATCC 55076 AQZ65316.1    
 BKM31_49760   [Actinomadura] parvosata subsp. kistnae ATCC 55076 AQZ68491.1    
 BKM31_46745   [Actinomadura] parvosata subsp. kistnae ATCC 55076 AQZ67968.1    
 BKM31_51920   [Actinomadura] parvosata subsp. kistnae ATCC 55076 AQZ68861.1    
 BKM31_55970   [Actinomadura] parvosata subsp. kistnae ATCC 55076 AQZ71379.1    
 L3i22_010680   Actinoplanes sp. L3-i22 BCY05980.1    
 ACTI_51170   Actinoplanes sp. OR16 BBH68432.1    
 SAMN04489717_1639   Actinopolymorpha singaporensis DSM 22024 SDS10494.1    
 SAMN04489717_3547   Actinopolymorpha singaporensis DSM 22024 SDS69346.1    
 SAMN04489717_2056   Actinopolymorpha singaporensis DSM 22024 SDS24044.1    
 KCV87_18035 (fragment)   Actinosynnema mirum ATCC 31280 QUF01472.1    
 Amir_0500 (fragment)   Actinosynnema mirum DSM 43827 ACU34467.1    
 APASM_0472 (fragment)   Actinosynnema pretiosum subsp. pretiosum ATCC 31280 AXX27837.1    
 CNX65_02545 (fragment)   Actinosynnema pretiosum X47 ATE52313.1    
 Pan181_06230 (CslA)   Aeoliella mucimassa Pan181 QDU54442.1     3
 I4Q36_06855   Aerococcaceae bacterium zg-1292 QQA36531.1     1
 IU367_09085   Aeromonas bestiarum YK48 WDL84309.1    
 AHGSH82_011490   Aeromonas hydrophila GSH8-2 BBG84004.1    
 MKW86_05845   Aeromonas hydrophila LP0103 UNB59610.1    
 U8518_02940   Aeromonas hydrophila MaAh001 WRK92653.1    
 RIMD111065_11110   Aeromonas hydrophila RIMD111065 BCO12755.1    
 WP8S18E02_11390   Aeromonas hydrophila WP8-S18-ESBL-02 BBT61342.1    
 K3G24_15810   Aeromonas veronii A29V UJP33590.1    
 MUN74_11990   Agromyces sp. H17E-10 UOQ88014.1    
 PYTT_0964   Akkermansia glycaniphila SEH81749.1    
 QET93_002775   Akkermansia sp. N21116 WPX41030.1    
 QET93_010960   Akkermansia sp. N21116 WPX40050.1    
 QET93_010385 (fragment)   Akkermansia sp. N21116 WPX41797.1     3
 OM944_03825   Algoriphagus sp. TR-M5 UZD23622.1     3
 PBT90_09495   Algoriphagus sp. TR-M9 WBL44915.1     3
 VFA0994   Aliivibrio fischeri ES114 AAW88064.1    
 VFMJ11_A1113   Aliivibrio fischeri MJ11 ACH64505.1    
 AI2BBH_05660   Alistipes indistinctus 2BBH45 BCG53520.1    
 AI2BBH_18540   Alistipes indistinctus 2BBH45 BCG54808.1    
 AI2BBH_05670   Alistipes indistinctus 2BBH45 BCG53521.1    
 NQ495_09330   Alistipes indistinctus YIT 12060 UWN58922.1    
 NQ495_03520   Alistipes indistinctus YIT 12060 UWN60039.1    
 NQ495_09325   Alistipes indistinctus YIT 12060 UWN58921.1    
 NQ519_11365   Alistipes senegalensis JC50 UWN64351.1    
 AL1_08200   Alistipes shahii WAL 8301 CBK63375.1     2
 AL1_00280   Alistipes shahii WAL 8301 CBK62766.1    
 AL1_08220   Alistipes shahii WAL 8301 CBK63377.1     2
 NQ492_01935   Alistipes shahii WAL 8301 UWN68667.1     2
 NQ492_01945   Alistipes shahii WAL 8301 UWN68669.1     2
 NQ492_05140   Alistipes shahii WAL 8301 UWN69262.1    
 NMU03_09795   Allocoprobacillus halotolerans LH1062 UTY37996.1    
 SAMN04489726_5005   Allokutzneria albata DSM 44149 SDN11771.1    
 LWP59_20510   Amycolatopsis acidiphila KCTC 39523 UIJ56575.1    
 A4R43_15665   Amycolatopsis albispora WP1 AXB43782.1    
 AJAP_14535   Amycolatopsis japonica MG417-CF17 AIG75785.1    
 SAMN04489733_0800   Amycolatopsis keratiniphila FH 1893 SDU06084.1    
 BB31_37720   Amycolatopsis lurida NRRL 2430 AJK58748.1    
 ISP_006106   Amycolatopsis mediterranei ISP5501 UZF72728.1    
 B737_5886   Amycolatopsis mediterranei RB AGT86550.1    
 AMES_5886   Amycolatopsis mediterranei S699 AFO79422.1
AEK44599.1		    
 AMED_5970   Amycolatopsis mediterranei U32 ADJ47711.1    
 QRX60_46655   Amycolatopsis mongoliensis 4-36 WIY01430.1    
 SD37_24605   Amycolatopsis orientalis B-37 ANN18491.1    
 AORI_4997   Amycolatopsis orientalis HCCB10007 AGM07581.1    
 MUY14_06020   Amycolatopsis pretoriensis FBCC-B4732 UOX90183.1    
 VSH64_17275   Amycolatopsis rhabdoformis NCIMB 14900 WSE33836.1    
 NQK81_41985   Amycolatopsis roodepoortensis ZEL-1 UUV31250.1    
 QRX50_27815   Amycolatopsis sp. 2-15 WIX75328.1    
 QP939_32935   Amycolatopsis sp. 2-2 WIV53668.1    
 CU254_22185   Amycolatopsis sp. AA4 ATY12857.1    
 BKN51_17440   Amycolatopsis sp. BJA-103 AUI59813.1    
 HUW46_07146 (XlY)   Amycolatopsis sp. CA-230715 QWF83703.1    
 QRY02_20850   Amycolatopsis sp. DG1A-15b WIX92755.1    
 K1T34_50635   Amycolatopsis sp. DSM 110486 QYN20644.1    
 MJQ72_23380   Amycolatopsis sp. EV170708-02-1 UMO99495.1    
 DJ578_42155   Amycolatopsis sp. FG22 QNF48726.1    
 L3Q65_17255   Amycolatopsis sp. FU40 UKD58399.1    
 HUT10_11850   Amycolatopsis sp. Hca4 QKV74383.1    
 CVV72_03455   Amycolatopsis sp. TNS106 QXV56173.1    
 HKG02Y_52410   Amycolatopsis sp. TUA-HKG02Y BCV13848.1    
 MUY22_44745   Amycolatopsis sp. WQ 127309 UOZ05862.1    
 YIM_14790 (XlY)   Amycolatopsis sp. YIM 10 QFU88143.1    
 STSP2_00558 (CslA)   Anaerohalosphaera lusitana ST-NAGAB-D1 AQT67414.1    
 ETAA8_70840 (CslA) (fragment)   Anatilimnocola aggregata ETA_A8 QDU31922.1     3
 FSB73_00635 (fragment)   Arachidicoccus ginsenosidivorans Gsoil 809 QEC70441.1    
 FSB73_00630 (fragment)   Arachidicoccus ginsenosidivorans Gsoil 809 QEC70440.1     3
 D6B99_12950   Arachidicoccus soli KIS59-12 AYD48430.1     3
 D6B99_15435   Arachidicoccus soli KIS59-12 AYD48878.1     3
 D6B99_14525   Arachidicoccus soli KIS59-12 AYD48711.1     3
 D6B99_04970   Arachidicoccus soli KIS59-12 AYD47020.1     2
 J0916_01240   Arthrobacter polaris C1-1 UIK89144.1    
 MB46_19365   Arthrobacter sp. A3 ALV47837.1    
 NVV90_17080   Arthrobacter sp. CJ23 UVJ38907.1    
 NVV90_15890   Arthrobacter sp. CJ23 UVJ38686.1    
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