Polysaccharide Lyase Family 8

Activities in Familyhyaluronate lyase (EC 4.2.2.1); chondroitin AC lyase (EC 4.2.2.5); xanthan lyase (EC 4.2.2.12); chondroitin ABC lyase (EC 4.2.2.20)
Mechanism b-elimination
3D Structure Status( α / α ) 5,6 toroid + anti-parallel β-sheet
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (2333); Uniprot accession (198); PDB accession (45); 3D entries (10); cryst (1)
All (2252) Archaea (2) Bacteria (2242) Eukaryota (8) Structure (10 - 1 cryst) Characterized (28)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 23 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 EF847_08160   Actinobacteria bacterium YIM 96077 AYY12689.1    
 ACTI_51170   Actinoplanes sp. OR16 BBH68432.1    
 SAMN04489717_1639   Actinopolymorpha singaporensis DSM 22024 SDS10494.1    
 SAMN04489717_3547   Actinopolymorpha singaporensis DSM 22024 SDS69346.1    
 SAMN04489717_2056   Actinopolymorpha singaporensis DSM 22024 SDS24044.1    
 Amir_0500 (fragment)   Actinosynnema mirum DSM 43827 ACU34467.1 C6WI16  
 APASM_0472 (fragment)   Actinosynnema pretiosum subsp. pretiosum ATCC 31280 AXX27837.1    
 CNX65_02545 (fragment)   Actinosynnema pretiosum X47 ATE52313.1    
 AHGSH82_011490   Aeromonas hydrophila GSH8-2 BBG84004.1    
 PYTT_0964   Akkermansia glycaniphila SEH81749.1    
 APS56_13715   Algibacter alginicilyticus HZ22 ALJ06121.1     3
 APS56_04640   Algibacter alginicilyticus HZ22 ALJ04469.1     2
 APS56_13745   Algibacter alginicilyticus HZ22 ALJ06125.1     3
 APS56_04620   Algibacter alginicilyticus HZ22 ALJ04465.1     2
 VFA0994 4.2.2.1 Aliivibrio fischeri ES114 AAW88064.1 Q5DYT2  
 VFMJ11_A1113   Aliivibrio fischeri MJ11 ACH64505.1 B5EVE3  
 AL1_08200   Alistipes shahii WAL 8301 CBK63375.1 D4IKB3   2
 AL1_00280   Alistipes shahii WAL 8301 CBK62766.1 D4IIK4  
 AL1_08220   Alistipes shahii WAL 8301 CBK63377.1 D4IKB5   2
 SAMN04489726_5005   Allokutzneria albata DSM 44149 SDN11771.1    
 A4R43_15665   Amycolatopsis albispora WP1 AXB43782.1    
 AJAP_14535   Amycolatopsis japonica MG417-CF17 AIG75785.1    
 SAMN04489733_0800   Amycolatopsis keratiniphila FH 1893 SDU06084.1    
 BB31_37720   Amycolatopsis lurida NRRL 2430 AJK58748.1    
 B737_5886   Amycolatopsis mediterranei RB AGT86550.1    
 AMES_5886   Amycolatopsis mediterranei S699 AFO79422.1
AEK44599.1
   
 AMED_5970   Amycolatopsis mediterranei U32 ADJ47711.1 D8HN29  
 SD37_24605   Amycolatopsis orientalis B-37 ANN18491.1    
 AORI_4997   Amycolatopsis orientalis HCCB10007 AGM07581.1    
 CU254_22185   Amycolatopsis sp. AA4 ATY12857.1    
 BKN51_17440   Amycolatopsis sp. BJA-103 AUI59813.1    
 YIM_14790 (XlY)   Amycolatopsis sp. YIM 10 QFU88143.1    
 FSB73_00635 (fragment)   Arachidicoccus ginsenosidivorans Gsoil 809 QEC70441.1    
 FSB73_00630 (fragment)   Arachidicoccus ginsenosidivorans Gsoil 809 QEC70440.1     3
 E0W69_012000   Arachidicoccus sp. B3-10 QES89354.1     3
 D6B99_12950   Arachidicoccus sp. KIS59-12 AYD48430.1     3
 D6B99_15435   Arachidicoccus sp. KIS59-12 AYD48878.1     3
 D6B99_14525   Arachidicoccus sp. KIS59-12 AYD48711.1     3
 D6B99_04970   Arachidicoccus sp. KIS59-12 AYD47020.1     2
 MB46_19365   Arthrobacter sp. A3 ALV47837.1    
 AL755_00180   Arthrobacter sp. ERGS1:01 ALE04181.1    
 AL755_04595   Arthrobacter sp. ERGS1:01 ALE04933.1    
 Arth_1698   Arthrobacter sp. FB24 ABK03092.1 A0JVM2  
 chondroitin lyase (Choa1)   Arthrobacter sp. GAG ANC28180.1    
 AHiyo8_07950 (fragment)   Arthrobacter sp. Hiyo8 BAS12492.1    
 chondroitin sulfate lyase (ChoA1)   Arthrobacter sp. MAT3885 AFM38168.1    
 ART_3702   Arthrobacter sp. PAMC 25486 AIY03301.1    
 ART_3703   Arthrobacter sp. PAMC 25486 AIY03302.1     2
 ARUE_c32170   Arthrobacter sp. Rue61a AFR30098.1    
 ARUE_232p01360 (short fragment)   Arthrobacter sp. Rue61a AFR31344.1    
 CGK93_17430   Arthrobacter sp. YN ASN21263.1    
 EIA51_01230   Avibacterium paragallinarum FARPER-174 AZI15197.1     2
 EIA51_07155   Avibacterium paragallinarum FARPER-174 AZI14404.1     2
 NCTC3438_00390   Avibacterium volantium NCTC3438 VEB22329.1     2
 NCTC3438_01189   Avibacterium volantium NCTC3438 VEB23811.1     2
 CY96_17710   Bacillus bombysepticus str. Wang AHX19751.1    
 pE33L466_0352   Bacillus cereus E33L AAY60495.1
AJI26182.1
Q4V1B2  
 heparinase (Hep)   Bacillus circulans BAB91369.1 Q8KKH9   2
 C2I06_04330   Bacillus circulans PK3_109 AYV66165.1    
 C2H98_05220   Bacillus circulans PK3_138 AYV71019.1    
 AM592_01170   Bacillus gobiensis FJAT-4402 ALC80364.1    
 NCTC4824_01130   Bacillus lentus NCTC4824 SQI53825.1    
 NCTC4824_01128   Bacillus lentus NCTC4824 SQI53822.1    
 NCTC4824_03984   Bacillus lentus NCTC4824 SQI63227.1    
 hyaluronate lyase (BniHL)   Bacillus niacini F8 BAO57293.1    
 Bsel_0843   [Bacillus] selenitireducens MLS10 ADH98369.1 D6XZJ5  
 hyaluronidase (Hyl;HAase-B) (partial) 4.2.2.1 Bacillus sp. A50 AHB61202.1    
 xanthan lyase (Xly) 4.2.2.12 Bacillus sp. GL1 BAB21059.1 Q9AQS0 1J0M[A]
1J0N[A]
1X1H[A]
1X1I[A]
1X1J[A]
2E22[A]
2E24[A]
 CT694_29655   Bacillus wiedmannii bv. thuringiensis FCC41 AZJ24099.1    
 CGC64_05665   Bacteroides caccae ATCC 43185 ASM65495.1     3
 CGC64_15715   Bacteroides caccae ATCC 43185 ASM67245.1    
 CGC64_04155   Bacteroides caccae ATCC 43185 ASM65228.1     2
 CGC64_04295   Bacteroides caccae ATCC 43185 ASM65253.1     2
 A4V03_19125   Bacteroides caecimuris I48 ANU59423.1     2
 A4V03_18910   Bacteroides caecimuris I48 ANU59382.1     2
 BcellWH2_01185 (Csla_2)   Bacteroides cellulosilyticus WH2 ALJ58447.1    
 BcellWH2_03149 (Csla_5)   Bacteroides cellulosilyticus WH2 ALJ60386.1    
 BcellWH2_02521   Bacteroides cellulosilyticus WH2 ALJ59760.1     2
 BcellWH2_03154 (Csla_6)   Bacteroides cellulosilyticus WH2 ALJ60391.1    
 BcellWH2_02528 (ChonabC)   Bacteroides cellulosilyticus WH2 ALJ59767.1     2
 BcellWH2_03147 (Csla_4)   Bacteroides cellulosilyticus WH2 ALJ60384.1    
 BcellWH2_00910 (Csla_1)   Bacteroides cellulosilyticus WH2 ALJ58172.1     3
 BF638R_1599   Bacteroides fragilis 638R CBW22130.1 E1WTQ7  
 MB0529_01465 (CslA)   Bacteroides fragilis BE1 CUA18113.1    
 VU15_06680   Bacteroides fragilis BOB25 AKA51421.1    
 E0L14_12195   Bacteroides fragilis CCUG4856T QCT78112.1    
 EC81_012280   Bacteroides fragilis DCMOUH0017B QCQ54523.1    
 EE52_019645   Bacteroides fragilis DCMOUH0018B QCQ51442.1    
 HR50_011370   Bacteroides fragilis DCMOUH0042B QCQ41166.1    
 IA74_010970   Bacteroides fragilis DCMOUH0067B QCQ36591.1    
 IB64_012000   Bacteroides fragilis DCMOUH0085B QCQ32309.1    
 EC80_011780   Bacteroides fragilis DCMSKEJBY0001B QCQ45478.1    
 BF1599   Bacteroides fragilis NCTC 9343 CAH07300.1 Q5LEZ9  
 BUN20_05190   Bacteroides fragilis Q1F2 AUI46044.1    
 BUN20_15725 (fragment)   Bacteroides fragilis Q1F2 AUI47874.1    
 BUN20_11965   Bacteroides fragilis Q1F2 AUI47223.1    
 AE940_04150   Bacteroides fragilis S14 ANQ60073.1    
 BF1585   Bacteroides fragilis YCH46 BAD48335.1 Q64VZ1  
 Bache_0583   Bacteroides helcogenes P 36-108 ADV42608.1     2
 Bache_0581   Bacteroides helcogenes P 36-108 ADV42606.1     3
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