Polysaccharide Lyase Family 8

Activities in Family	Exo-β-1,4-glucuronan lyase (EC 4.2.2.-); Exo-hyaluronate lyase (EC 4.2.2.-); Hyaluronate lyase (EC 4.2.2.1); Xanthan lyase (EC 4.2.2.12); Chondroitinase B (EC 4.2.2.19); Poly(β-mannuronate) lyase / M-specific alginate lyase (EC 4.2.2.3); Chondroitin AC lyase (EC 4.2.2.5); Heparin lyase / heparin lyase I (EC 4.2.2.7);
Mechanism	b-elimination
3D Structure Status	( α / α ) ₆ toroid + anti-parallel β-sheet
Commercial Enzyme Provider(s)	MEGAZYME; PROZOMIX;
Statistics	GenBank accession (4807); Uniprot accession (30); PDB accession (54); 3D entries (13); cryst (1)

Summary

Download PL8 (5166) Taxonomic display Structure (13 - 1 cryst) Characterized (33)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
GJU35_32115		Streptomyces lincolnensis B48	QMV09848.1
SLCG_2439		Streptomyces lincolnensis LC-G	AXG53594.1
SLINC_5976		Streptomyces lincolnensis NRRL 2936	ANS68200.1
SLITK23_53760		Streptomyces lividans TK23	BDE42131.1
SLIV_10835		Streptomyces lividans TK24	AIJ13162.1
LGI35_07780		Streptomyces longhuiensis BH-MK-02	UDL98157.1
LGI35_30395		Streptomyces longhuiensis BH-MK-02	UDM02273.1
LGI35_35640		Streptomyces longhuiensis BH-MK-02	UDM03222.1
LGI35_23800		Streptomyces longhuiensis BH-MK-02	UDM01080.1
SLUN_28075		Streptomyces lunaelactis MM109	AVZ77683.1
EKH77_23185		Streptomyces luteoverticillatus CGMCC 15060	AZQ73741.1
SL103_28195		Streptomyces lydicus 103	AOP49608.1
LJ741_27290		Streptomyces lydicus M01	UEG93923.1
DDE74_28255		Streptomyces lydicus WYEC 108	AZS76712.1
SMALA_0375		Streptomyces malaysiensis DSM 4137	ATL80618.1 QDL74780.1
DNK48_02015		Streptomyces malaysiensis DSM 4137	QDL68347.1 ATL88356.1
R8789_41955		Streptomyces malaysiensis NA3722	WPB95203.1
R8789_02165		Streptomyces malaysiensis NA3722	WPB88124.1
LC193_00340		Streptomyces marincola SCSIO 64649	UCM86519.1
LC193_26105		Streptomyces marincola SCSIO 64649	UCM91138.1
SFUL_16		Streptomyces microflavus DSM 40593	AGK75001.1
SMIR_37530		Streptomyces mirabilis P16B-1	QUW84140.1
K7I03_09170		Streptomyces mobaraensis DSM 40587	UBI36613.1
J7W19_23170		Streptomyces mobaraensis NBRC 13819 = DSM 40847	QTT75898.1
POD33_21060		Streptomyces moderatus DT446	WCH94489.1
GO605_16160		Streptomyces murinus CR-43	UWW92209.1
ME763_01280		Streptomyces murinus JS029	WDO04387.1
WEB32_24415		Streptomyces netropsis M-141	WXH41222.1
DC008_24835		Streptomyces nigra 452	AWE52609.1
STRNI_002676		Streptomyces nigrescens DSM 40276	WAU04406.1
HEK616_54990		Streptomyces nigrescens HEK616	BDM72012.1
BBN63_14395		Streptomyces niveus SCSIO 3406	AQU67257.1
JNO44_29575		Streptomyces noursei A-2-1	QRX94442.1
SNOUR_13955		Streptomyces noursei ATCC 11455	ANZ16093.1
SAZ_29920		Streptomyces noursei ZPM	AKA06207.1
MMU79_21450		Streptomyces olivaceus B-81	WFB85687.1
QZH56_08835		Streptomyces olivoreticuli ZZ-21	WKK25679.1
B1H29_10935		Streptomyces pactum ACT12	AQS71926.1
BC342_25060		Streptomyces pactum KLBMP 5084	AOW91390.1
DVK44_25640		Streptomyces paludis GSSD-12	AXG82901.1
Spa2297_23435		Streptomyces parvulus 2297	ANJ11652.1
OGH68_20240		Streptomyces peucetius NA0869	UYQ63554.1
OGH68_31010		Streptomyces peucetius NA0869	UYQ65458.1
OHB35_17490		Streptomyces phaeochromogenes NBC 01752	WSD14892.1
OG931_16155		Streptomyces phaeochromogenes NBC_00186	WRZ29175.1
F9278_35050		Streptomyces phaeolivaceus GY16	QFR00533.1
CP981_27530		Streptomyces platensis ATCC 23948	QEV54887.1
Sfla_2926		Streptomyces pratensis ATCC 33331	ADW04353.1
SPRI_3462		Streptomyces pristinaespiralis HCCB 10218	ALC21768.1
SPRI_4720		Streptomyces pristinaespiralis HCCB 10218	ALC23026.1
H3L99_19670		Streptomyces pristinaespiralis PR11	QMU15542.1
H3L99_13235		Streptomyces pristinaespiralis PR11	QMU14445.1
BFF78_03435		Streptomyces puniciscabiei TW1S1	AOR30237.1
A4E84_28340		Streptomyces qaidamensis S10(2016)	AMW13060.1
FQU76_24730		Streptomyces qinzhouensis SSL-25	QDY79193.1
LUW77_30535		Streptomyces radiopugnans MRC003	URN14113.1
LIV37_46720		Streptomyces rapamycinicus NRRL 5491	UTP36120.1
LIV37_12090		Streptomyces rapamycinicus NRRL 5491	UTP30037.1
M271_11920		Streptomyces rapamycinicus NRRL 5491	AGP53981.1
M271_45980		Streptomyces rapamycinicus NRRL 5491	AGP60561.1
LJB45_06975		Streptomyces rapamycinicus SRMK07	UTO62085.1
FGW37_23350		Streptomyces rectiverticillatus B15-08	QLE76283.1
TUE45_06045 (XlY)		Streptomyces reticuli	CUW31307.1
CP984_11465		Streptomyces rimosus ATCC 10970	QEV75558.1
V519_017665		Streptomyces rimosus R6-500	QGY67506.1
SRIM_029145		Streptomyces rimosus subsp. rimosus ATCC 10970	QST83699.1
SRIMDV3_09275 (XlY)		Streptomyces rimosus subsp. rimosus DV3	UTJ12425.1
SRIMHP_09380 (XlY)		Streptomyces rimosus subsp. rimosus HP126	UTH94328.1
SRIMR7_11540 (XlY)		Streptomyces rimosus subsp. rimosus R7	UNZ02776.1
FMM49_12010		Streptomyces rimosus subsp. rimosus SRI-4018v0	QTL86366.1
CTZ40_11495		Streptomyces rimosus WT5260	QDA04274.1
SRO_0644		Streptomyces rochei 7434AN4	BBC91820.1
TR631_26710		Streptomyces rochei D21E05	WQC15218.1
P7W03_25495		Streptomyces rochei JK1	WMC88742.1
RBH85_10230		Streptomyces rochei S32	WMI57114.1
RGF97_30970		Streptomyces roseicoloratus T14	WMX48335.1
SCAB_26801		Streptomyces scabiei 87.22	CBG69783.1
A7J05_08365		Streptomyces silaceus ACCC40021	APY85723.1 QGW50781.1
I1A49_44455		Streptomyces solisilvae HNM0141	QPI61031.1
I1A49_05395		Streptomyces solisilvae HNM0141	QPI54448.1
CGL27_04770		Streptomyces sp. 11-1-2	ASQ92555.1
P8T65_13160		Streptomyces sp. 11x1	WNZ08444.1
SAMN05428941_5645		Streptomyces sp. 2114.2	SDT75626.1
SAMN06272775_1968		Streptomyces sp. 2323.1	SOE10947.1
OYE22_28345		Streptomyces sp. 71268	WEV28655.1			2
GZL_03204		Streptomyces sp. 769	AJC55790.1
HC362_05760		Streptomyces sp. 891-h	UNZ16655.1
T261_2519		Streptomyces sp. A02	AJT64193.3 AJT64193.1 AJT64193.2
HRD51_28105		Streptomyces sp. A1-5	UJB44154.1
K5X85_25195		Streptomyces sp. A144	UAX56086.1
DKB30_26260		Streptomyces sp. Ae707_A7	QNF67081.1
AS97_40750		Streptomyces sp. AgN23	QTI87379.1
AS97_41945		Streptomyces sp. AgN23	QTI90681.1
P8A21_01270		Streptomyces sp. Alt1	WLQ46211.1
P8A21_28625		Streptomyces sp. Alt1	WLQ53506.1
P8A21_35515		Streptomyces sp. Alt1	WLQ52481.1
P8A19_04580		Streptomyces sp. Alt2	WLQ54754.1
P8A19_12075		Streptomyces sp. Alt2	WLQ61655.1
P8A19_39765		Streptomyces sp. Alt2	WLQ61193.1
P8A20_16705		Streptomyces sp. Alt3	WLQ65140.1
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