Polysaccharide Lyase Family 8

Activities in Family	Exo-β-1,4-glucuronan lyase (EC 4.2.2.-); Exo-hyaluronate lyase (EC 4.2.2.-); Hyaluronate lyase (EC 4.2.2.1); Xanthan lyase (EC 4.2.2.12); Chondroitinase B (EC 4.2.2.19); Poly(β-mannuronate) lyase / M-specific alginate lyase (EC 4.2.2.3); Chondroitin AC lyase (EC 4.2.2.5); Heparin lyase / heparin lyase I (EC 4.2.2.7);
Mechanism	b-elimination
3D Structure Status	( α / α ) ₆ toroid + anti-parallel β-sheet
Commercial Enzyme Provider(s)	MEGAZYME; PROZOMIX;
Statistics	GenBank accession (4807); Uniprot accession (30); PDB accession (54); 3D entries (13); cryst (1)

Summary

Download PL8 (5166) Taxonomic display Structure (13 - 1 cryst) Characterized (33)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
MUK60_13720		Streptomyces sp. LRE541	UPZ28774.1
LRS74_09355		Streptomyces sp. LX-29	WFB07231.1
H3V39_32975		Streptomyces sp. M54	QSS94735.1
CFP59_00531 (CslA)		Streptomyces sp. M56	AUA08446.1
CFP59_08192 (XlY)		Streptomyces sp. M56	AUA16002.1
M6G08_15720		Streptomyces sp. M92	WCN03441.1
K4G22_26775		Streptomyces sp. MA3_2.13	UED87371.1
STRMOE7_27170		Streptomyces sp. MOE7	ARH93359.1
P8A18_30695		Streptomyces sp. Mut1	WLQ37541.1
HUT08_05485		Streptomyces sp. NA00687	QKW49086.1			2
HUT19_36270		Streptomyces sp. NA02950	QKV96492.1
HUT15_10195		Streptomyces sp. NA03103	QKW65624.1
HUT18_32555		Streptomyces sp. NA04227	QKW10446.1			2
HUT18_22130		Streptomyces sp. NA04227	QKW08672.1
QFW82_02660		Streptomyces sp. NA07423	WHX15985.1
QFW82_41060		Streptomyces sp. NA07423	WHX24429.1
OG428_19105		Streptomyces sp. NBC_01422	WUX98474.1
OG428_00985		Streptomyces sp. NBC_01422	WUX95180.1
OG906_05570		Streptomyces sp. NBC_01426	WUX80900.1
OG406_06355		Streptomyces sp. NBC_01428	WUX73409.1
OG627_08530		Streptomyces sp. NBC_01429	WUX66960.1
OG522_11345		Streptomyces sp. NBC_01431	WUX59661.1
OG574_17155		Streptomyces sp. NBC_01445	WSE04934.1
OG574_12110		Streptomyces sp. NBC_01445	WSE04037.1
OG574_23785		Streptomyces sp. NBC_01445	WSE06104.1
OIU81_10260		Streptomyces sp. NBC_01454	WUW70174.1
OG875_13100		Streptomyces sp. NBC_01498	WTL25445.1
DKG71_29200		Streptomyces sp. NEAU-S7GS2	AWN29694.1
DEH18_26300		Streptomyces sp. NHF165	QHF96777.1
QTO28_17745		Streptomyces sp. P9-2B-1	WJY32721.1
QT196_28360		Streptomyces sp. P9-2B-2	WJY40879.1
F750_3862		Streptomyces sp. PAMC 26508	AGJ56308.1
QR97_09255		Streptomyces sp. PBH53	AKN69995.1
V2W30_34375		Streptomyces sp. Q6	WWQ67919.1
V2W30_20765		Streptomyces sp. Q6	WWQ65510.1
V2W30_02855		Streptomyces sp. Q6	WWQ62405.1
V2W30_37385		Streptomyces sp. Q6	WWQ68453.1
GPZ77_04540		Streptomyces sp. QHH-9511	QGZ52768.1
LZ559_34400		Streptomyces sp. R527F	UIZ17129.1
HYQ63_29910		Streptomyces sp. Rer75	QLH24333.1
HEP84_07625		Streptomyces sp. RLB1-33	QIY69090.1
HEP86_28570		Streptomyces sp. RPA4-5	QIY60091.1
SSPS47_19405 (Xly2)		Streptomyces sp. S4.7	QHY97278.1
N6H00_35210		Streptomyces sp. S465	WAP59778.1
D7Y56_18050		Streptomyces sp. S501	QBR07645.1
A6E92_00270		Streptomyces sp. S8	ARI50739.1
A8713_22525		Streptomyces sp. SAT1	ANH93601.1
A8713_00365		Streptomyces sp. SAT1	ANH89775.1
SBE_004329		Streptomyces sp. SBE_14.2	WBO80545.1
SBE_005962		Streptomyces sp. SBE_14.2	WBO82066.1
PS467_36370		Streptomyces sp. SCA4-21	WNF00415.1
CAG99_27135		Streptomyces sp. SCSIO 03032	ARQ72015.1
CAG99_02580		Streptomyces sp. SCSIO 03032	ARQ67866.1
silent information regulator protein Sir2		Streptomyces sp. SCSIO 03032	ARP51738.1
C1N79_25645		Streptomyces sp. SGAir0924	QCR49728.1
QFA72_33760		Streptomyces sp. SH5	WGP14292.1
RVR_8953		Streptomyces sp. SN-593	BBB01505.1
RVR_4250		Streptomyces sp. SN-593	BBA98169.1
HBB06_12205		Streptomyces sp. SNU607	WKV78866.1
C8250_029970		Streptomyces sp. So13.3	QNA75552.1
E5N77_25305		Streptomyces sp. SS52	QCB24773.1
GEV49_11475		Streptomyces sp. SYP-A7193	QFX86123.1
PBV52_00920		Streptomyces sp. T12	WDF35464.1
PBV52_34330		Streptomyces sp. T12	WDF41514.1
SAMN05216371_7965		Streptomyces sp. TLI_053	SDT83152.1
GLX30_16595		Streptomyces sp. Tu 2975	QIP85387.1
TK78_00655		Streptomyces sp. Tue 6075 Tue6075	APS17604.1
MCU78_09150		Streptomyces sp. TYQ1024	UKW29205.1
KE639_05248 (XlY)		Streptomyces sp. V17-9	QUW93995.1
OH133_37050		Streptomyces sp. VB1	UZI33253.1
OH133_00845		Streptomyces sp. VB1	UZI26775.1
EZV63_25850		Streptomyces sp. VN1	QIP72839.1
Q3V23_25825		Streptomyces sp. VNUA116	WKU47200.1
PYR72_15760		Streptomyces sp. VNUA24	WEH15098.1
Q3101_23980		Streptomyces sp. VNUA74	WML82726.1
LEL86_18845		Streptomyces sp. WA6-1-16	UCA51208.1
DMA15_33340		Streptomyces sp. WAC 01529	AZM56863.1
DMA15_29615		Streptomyces sp. WAC 01529	AZM56237.1
DMB38_15580		Streptomyces sp. WAC 06738	AZM47040.1
DMB38_35890		Streptomyces sp. WAC 06738	AZM50462.1
DMB38_35920		Streptomyces sp. WAC 06738	AZM50466.1
DMB38_25125		Streptomyces sp. WAC 06738	AZM48635.1
C5L38_01150		Streptomyces sp. WAC00288	AVH93839.1
MWG59_00770		Streptomyces sp. WAC00303	UPT40076.1
MWG59_37200		Streptomyces sp. WAC00303	UPT46523.1
O7599_11655		Streptomyces sp. WMMC500	WBB63135.1
O7599_21365		Streptomyces sp. WMMC500	WBB58190.1
QHG49_32270		Streptomyces sp. WP-1	WKE73353.1
KV381_35740		Streptomyces sp. WY228	QXR01153.1
KV381_01020		Streptomyces sp. WY228	QXQ95039.1
IPZ77_15520		Streptomyces sp. XC 2026	QQN78694.1
Q3Y56_25420		Streptomyces sp. XD-27	WKX72796.1
StreXyl84_75060		Streptomyces sp. Xyl84	BFD88105.1
StreXyl84_19040		Streptomyces sp. Xyl84	BFD82503.1
C9F11_36765 (Xly2)		Streptomyces sp. YIM 121038	QCX80936.1
C9F11_05885 (Xly1)		Streptomyces sp. YIM 121038	QCX74878.1
KME66_00755		Streptomyces sp. YPW6	QWQ39682.1
CP982_37460		Streptomyces spectabilis ATCC 27465	QEV63684.1
CP982_06315		Streptomyces spectabilis ATCC 27465	QEV58366.1
FH965_35840		Streptomyces spectabilis NRRL 2792	QDQ15267.1
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