| Activities in Family | Trans-sialidase (EC 2.4.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-); Kdo hydrolase (EC 3.2.1.124); Exo-α-sialidase (EC 3.2.1.18); Anhydrosialidase (EC 4.2.2.15); |
|---|---|
| Mechanism | Retaining e |
| Clan | GH-E |
| 3D Structure Status | 6-fold β-propeller |
| Catalytic Nucleophile/Base | Tyr+Glu |
| Catalytic Proton Donor | Not known |
| External resources | CAZypedia; HOMSTRAD; |
| Commercial Enzyme Provider(s) | MEGAZYME; |
| Statistics | GenBank accession (11188); Uniprot accession (128); PDB accession (186); 3D entries (29); cryst (0) |
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| Eukaryota | |||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | ||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01558.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01559.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01560.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01561.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01562.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01563.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01564.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01565.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01566.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01567.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01568.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01569.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01570.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01571.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01572.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01573.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01574.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01575.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGA01576.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGI37819.1 | |||||
| trans-sialidase, partial (TS) (fragment) | Trypanosoma cruzi | AGI37820.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07400.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07401.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07402.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07403.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07404.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07405.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07406.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07407.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07408.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07409.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07410.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07411.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07412.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07413.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07414.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07415.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07416.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07417.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07418.1 | |||||
| 85 kDa surface glycoprotein (fragment) | Trypanosoma cruzi | AAT07419.1 | |||||
| amastigote surface protein 2 (Asp-2) (partial) | Trypanosoma cruzi BRAZIL | AAC47720.1 | |||||
| shed-acute-phase-antigen (SapA) | Trypanosoma cruzi CAI | CAA40511.1 | |||||
| flagellum-associated protein FL-160-3 | Trypanosoma cruzi CL | CAA50288.1 | |||||
| P85.1 | Trypanosoma cruzi CL | AAD13334.1 | |||||
| P85.2 | Trypanosoma cruzi CL | AAD13335.1 | |||||
| sialidase 85-1.1 | 3.2.1.18 | Trypanosoma cruzi CL | AAA30245.1 | P18269 | |||
| sialidase 85-1.2 (fragment) | Trypanosoma cruzi CL | CAA37618.1 | |||||
| sialidase SA85-1.2 | 3.2.1.18 | Trypanosoma cruzi CL | AAA30246.1 | Q03625 | |||
| trans-sialidase-like protein | Trypanosoma cruzi CL | ABO28970.1 | |||||
| surface antigen (Gp82) (fragment) | Trypanosoma cruzi CL / G | AAF02477.1 AAA21303.1 |
|||||
| trans-sialidase (TcTS;Tc00.1047053509495.30) | 2.4.1.- | Trypanosoma cruzi CL Brener | EAN85580.1 | Q4CZ79 | |||
| amastigote surface protein 3 (Asp-3) | Trypanosoma cruzi CL Brener | ACI02313.1 | |||||
| Tcc1j12.1 | Trypanosoma cruzi CL BRENER | AAL90887.1 | |||||
| Tcc1j12.4 | Trypanosoma cruzi CL BRENER | AAL90890.1 | |||||
| Tcc1j12.5 | Trypanosoma cruzi CL BRENER | AAL90891.1 | |||||
| surface antigen PHGST#5 | Trypanosoma cruzi CL BRENER | AAC79848.2 | |||||
| TcCLB.506331.90 / Tc00.1047053506331.90 | Trypanosoma cruzi CL Brener | EAN96369.1 | |||||
| trans-sialidase (TcTS-12) | 2.4.1.- | Trypanosoma cruzi CL BRENER | ACF17926.1 | B3VSM4 | |||
| trans-sialidase (TcTS-15) | 2.4.1.- | Trypanosoma cruzi CL BRENER | ACF17927.1 | B3VSM5 | |||
| trans-sialidase (TcTS-24) | 2.4.1.- | Trypanosoma cruzi CL BRENER | ACF17928.1 | B3VSM6 | |||
| trans-sialidase (TcTS-46) | 2.4.1.- | Trypanosoma cruzi CL BRENER | ACF17929.1 | B3VSM7 | |||
| trans-sialidase (TcTS-49) | 2.4.1.- | Trypanosoma cruzi CL BRENER | ACF17930.1 | B3VSM8 | |||
| trans-sialidase, partial (Tsα-1) (fragment) | Trypanosoma cruzi CL Brenner TSA-1 | AID66711.1 | |||||
| trans-sialidase, partial (Tsα-1) (fragment) | Trypanosoma cruzi CL Brenner TSA-1 | AID66712.1 | |||||
| surface protein-2 | Trypanosoma cruzi CL-BRENER | ABQ53588.1 | |||||
| surface protein-2 | Trypanosoma cruzi COLOMBIAN | ABQ53589.1 | |||||
| N-terminal trans-sialidase antigen, partial (fragment) | Trypanosoma cruzi cruzi | UGO57630.1 | |||||
| trans-sialidase C terminal antigen, partial (fragment) | Trypanosoma cruzi cruzi | UGO57629.1 | |||||
| trans-sialidase, partial (Tsα-1) (fragment) | Trypanosoma cruzi Esmeraldo cl3 TSA-1 | AID66713.1 | |||||
| surface glycoprotein GP90, partial | Trypanosoma cruzi G | AAM47176.2 | |||||
| GP82-related trans-sialidase | Trypanosoma cruzi G | ALO20095.1 | |||||
| 82-kDa surface antigen | Trypanosoma cruzi G | AIY32000.2 | |||||
| 82-kDa surface antigen, partial (fragment) | Trypanosoma cruzi G | ALQ10781.1 APG55778.1 |
|||||
| surface antigen GP90, partial | Trypanosoma cruzi G | APG55782.1 | |||||
| surface protein-2 | Trypanosoma cruzi G | ABQ53592.1 | |||||
| surface protein-2 | Trypanosoma cruzi G | ABQ53593.1 | |||||
| stage-specific surface protein (Gp82;SL2) | Trypanosoma cruzi G | ABR19835.1 ABR19836.1 AIY31990.1 AIY31992.1 AIY31993.1 AIY31994.1 AIY31995.1 AIY31996.1 AIY31999.1 AIY32000.1 ALQ10780.1 APG55781.1 APG55849.1 |
|||||
| 82-kDa surface antigen, partial (fragment) | Trypanosoma cruzi G | AIY31991.1 | |||||
| 82-kDa surface antigen, partial (fragment) | Trypanosoma cruzi G | AIY31997.1 | |||||
| 82-kDa surface antigen, partial (fragment) | Trypanosoma cruzi G | AIY31998.1 | |||||
| surface glycoprotein Gp90 | Trypanosoma cruzi G (KINETOPLAST) | AAM47176.1 | |||||
| surface glycoprotein GP90 (fragment) | Trypanosoma cruzi G (KINETOPLAST) | AAM47177.1 | |||||
| surface glycoprotein GP90 (fragment) | Trypanosoma cruzi G (KINETOPLAST) | AAM47178.1 | |||||
| glycoprotein 82 kDa (gp82 subfamily A1) (fragment) | Trypanosoma cruzi H1 | BAF74641.1 | |||||
| glycoprotein 82 kDa (gp82 subfamily A2) (fragment) | Trypanosoma cruzi H1 | BAF74642.1 | |||||
| glycoprotein 82 kDa (gp82 subfamily C1) (fragment) | Trypanosoma cruzi H1 | BAF74652.1 | |||||
| glycoprotein 82 kDa (gp82 subfamily A3) (fragment) | Trypanosoma cruzi H20 | BAF74643.1 | |||||
| glycoprotein 82 kDa (gp82 subfamily A4) (fragment) | Trypanosoma cruzi H20 | BAF74644.1 | |||||
| glycoprotein 82 kDa (gp82 subfamily C2) (fragment) | Trypanosoma cruzi H20 | BAF74653.1 | |||||
| trans-sialidase, partial | Trypanosoma cruzi marinkellei TCC426 | AHI17183.1 | |||||
| trans-sialidase, partial | Trypanosoma cruzi marinkellei TCC426 | AHI17184.1 | |||||
| glycoprotein 82 kDa (gp82 subfamily A5) (fragment) | Trypanosoma cruzi PERU1 | BAF74645.1 | |||||
| glycoprotein 82 kDa (gp82 subfamily B1) (fragment) | Trypanosoma cruzi PERU1 | BAF74648.1 | |||||
| glycoprotein 82 kDa (gp82 subfamily B2) (fragment) | Trypanosoma cruzi PERU1 | BAF74649.1 | |||||
| glycoprotein 82 kDa (gp82 subfamily C3) (fragment) | Trypanosoma cruzi PERU1 | BAF74654.1 | |||||
| glycoprotein 82 kDa (gp82 subfamily A6) (fragment) | Trypanosoma cruzi PERU2 | BAF74646.1 | |||||
| glycoprotein 82 kDa (gp82 subfamily A7) (fragment) | Trypanosoma cruzi PERU2 | BAF74647.1 | |||||
| glycoprotein 82 kDa (gp82 subfamily B3) (fragment) | Trypanosoma cruzi PERU2 | BAF74650.1 | |||||
| glycoprotein 82 kDa (gp82 subfamily B4) (fragment) | Trypanosoma cruzi PERU2 | BAF74651.1 | |||||
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