Activities in Family	Trans-sialidase (EC 2.4.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-); Kdo hydrolase (EC 3.2.1.124); Exo-α-sialidase (EC 3.2.1.18); Anhydrosialidase (EC 4.2.2.15);
Mechanism	Retaining e
Clan	GH-E
3D Structure Status	6-fold β-propeller
Catalytic Nucleophile/Base	Tyr+Glu
Catalytic Proton Donor	Not known
External resources	CAZypedia; HOMSTRAD;
Commercial Enzyme Provider(s)	MEGAZYME;
Statistics	GenBank accession (11064); Uniprot accession (128); PDB accession (186); 3D entries (29); cryst (0)

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Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
388805		Aaosphaeria arxii CBS 175.79 v1 (Aaoar1)
39889		Achaetomium macrosporum CBS 532.94 v1.0 (Achma1)
271857		Achaetomium strumarium CBS333.67 v1.0 (Achstr1)
I4U23_023608		Adineta vaga	UJR20480.1
I4U23_023539		Adineta vaga	UJR20408.1
I4U23_023610		Adineta vaga	UJR20482.1
I4U23_020305 (fragment)		Adineta vaga	UJR32843.1
I4U23_020304 (fragment)		Adineta vaga	UJR32842.1
482883		Alternaria alternata MPI-PUGE-AT-0064 v1.0 (Altalt1)
1045384		Alternaria alternata SRC1lrK2f v1 (Altal1)
CB5_LOCUS25028 (fragment)		Ananas comosus var. bracteatus	VUW74443.1 CAB5276718.1
CB5_LOCUS1899		Ananas comosus var. bracteatus	VUW51322.1 CAB5253597.1
CB5_LOCUS2438		Ananas comosus var. bracteatus	CAD1819227.1
sialidase 3 (Neu3)		Anguilla japonica	BBK08074.1
AARE701A_ LOCUS 21765		Arabidopsis arenosa	CAE6246080.1
At5g57700		Arabidopsis thaliana	ABL66729.1 ABN04833.1 AED96937.1 AED96938.1 AED96939.1 AED96940.1 ANM69688.1
DS421_1g22030		Arachis hypogaea	QHO50380.1
DS421_1g22040		Arachis hypogaea	QHO50381.1
DS421_11g350210		Arachis hypogaea	QHO21847.1
DS421_11g350210		Arachis hypogaea	QHO21847.1
5646		Arthroderma benhamiae CBS 112371 (Artbe1)
157621		Aspergillus arachidicola v1.0 (Aspara19utr)
305292		Aspergillus bertholletius IBT 29228 v1.0 (Aspber1)
55340		Aspergillus bertholletius IBT 29228 v1.0 (Aspber1)
4665		Aspergillus bombycis NRRL 26010 (Aspbom1)
46174		Aspergillus brasiliensis v1 (Aspbr1)
154540		Aspergillus caelatus CBS 763.97 v1.0 (Aspcae1)
768982		Aspergillus calidoustus (Aspcal1)
763888		Aspergillus calidoustus (Aspcal1)
G4B11_001939		Aspergillus flavus AF13	QMW38703.1
AFCA_002045		Aspergillus flavus CA14	UCK59223.1
F9C07_1010146		Aspergillus flavus NRRL 3357	QRD87235.1
G4B84_001869		Aspergillus flavus NRRL3357	QMW26624.1
34034		Aspergillus flavus NRRL3357 (Aspfl1)
1010146		Aspergillus flavus NRRL3357 v1.0 (Aspfl2_3)
106040		Aspergillus fumigatus A1163 (Aspfu_A1163_1)
2-keto-3-deoxynononic acid sialidase (KDNase;AfKDNase;Afu4g13800;AFUA_4G13800) (6407)	3.2.1.18 3.2.1.-	Aspergillus fumigatus Af293	EAL89414.2	Q4WQS0	2XCY[A,B] 2XZI[A,B] 2XZJ[A,B] 2XZK[A,B] 4M4N[A,B] 4M4U[A,B] 4M4V[A,B]
5806		Aspergillus fumigatus Af293 (Aspfu1)
19942		Aspergillus kawachii IFO 4308 (Aspka1_1)
200352		Aspergillus leporis CBS 151.66 v1.0 (Asplep1)
46947		Aspergillus acidus v1 (Aspfo1)
AKAW2_60324S		Aspergillus luchuensis IFO 4308	BCS02060.1
ALUC_60302S		Aspergillus luchuensis RIB2601	BCS13746.1
32967		Aspergillus minisclerotigenes v1.0 (Aspmin1)
1351		Aspergillus nidulans FGSC A4 (Aspnid1)
304782		Aspergillus phoenicis (Corda) Thom ATCC 13157 v1.0 (Aspph1)
1173330		Aspergillus niger ATCC 1015 v4 (Aspni7)
An15g04260		Aspergillus niger CBS 513.88	CAK97293.1
166945		Aspergillus niger CBS 513.88 (Aspni_DSM_1)
3901		Aspergillus niger NRRL3 (Aspni_NRRL3_1)
361385		Aspergillus niger van Tieghem ATCC 13496 v1.0 (Aspni_bvT_1)
155325		Aspergillus nomius v1.0 (Aspnom1)
362		Aspergillus nomius NRRL 13137 (Aspnom13137_1)
442247		Aspergillus novofumigatus IBT 16806 v1 (Aspnov1)
209478		Aspergillus novoparasiticus CBS 126849 v1.0 (Aspnovo1)
AO090005000203		Aspergillus oryzae RIB40	BAE55299.1
1850		Aspergillus oryzae RIB40 (Aspor1)
162877		Aspergillus parasiticus CBS 117618 v1.0 (Asppar1)
382243		Aspergillus parvisclerotigenus CBS 121.62 v1.0 (Asppari1)
304696		Aspergillus pseudocaelatus CBS 117616 v1.0 (Asppsec1)
289229		Aspergillus pseudonomius CBS 119388 v1.0 (Asppsen1)
281783		Aspergillus pseudotamarii CBS 117625 v1.0 (Asppset1)
APUU_41633A		Aspergillus puulaauensis MK2	BCS25189.1
APUU_31740S		Aspergillus puulaauensis MK2	BCS23515.1
APUU_40009A		Aspergillus puulaauensis MK2	BCS23565.1
195868		Aspergillus sergii CBS 130017 v1.0 (Aspser1)
92443		Aspergillus sydowii v1 (Aspsy1)
46413		Aspergillus sydowii v1 (Aspsy1)
47987		Aspergillus sydowii v1 (Aspsy1)
298546		Aspergillus tamarii CBS 117626 v1.0 (Asptam1)
9078		Aspergillus terreus NIH 2624 (Aspte1)
8527		Aspergillus terreus NIH 2624 (Aspte1)
KDNase (ATEG_04964)	3.2.1.-	Aspergillus terreus NIH2624	Q0CMX0		7P1B[A] 7P1D[A] 7P1E[A] 7P1F[A,B] 7P1O[A,B]
565405		Aspergillus transmontanensis CBS 130015 (Asptra1)
48337		Aspergillus tubingensis v1.0 (Asptu1)
6051		Aspergillus udagawae IFM 46973 (Aspuda1)
45440		Aspergillus versicolor v1 (Aspve1)
156144		Aspergillus versicolor v1 (Aspve1)
42550		Aspergillus versicolor v1 (Aspve1)
157130		Aspergillus welwitschiae CBS139.54b v1.0 (Aspwel1)
557061		Aspergillus wentii v1 (Aspwe1)
92515		Aspergillus zonatus v1 (Aspzo1)
sialidase-1a (Neu1A)		Astyanax mexicanus	BCM73181.1
sialidase-1b (Neu1B)		Astyanax mexicanus	BCM73182.1
sialidase 4 (Neu4) (fragment)		Astyanax mexicanus	BCU08941.1
sialidase 3 (Neu3)		Astyanax mexicanus	BCU08942.1
Bathy16g00540		Bathycoccus prasinos RCC1105	CCO20205.1
Bathy17g00380		Bathycoccus prasinos RCC1105	CCO20385.1
Bathy08g04480		Bathycoccus prasinos RCC1105	CCO17529.1
Bathy08g01990		Bathycoccus prasinos RCC1105	CCO17967.1
Bathy10g03050		Bathycoccus prasinos RCC1105	CCO18064.1
Bathy04g01130		Bathycoccus prasinos RCC1105	CCO16089.1
Bathy05g00010		Bathycoccus prasinos RCC1105	CCO16590.1
Bathy06g00870		Bathycoccus prasinos RCC1105	CCO17015.1
Bathy08g03560		Bathycoccus prasinos RCC1105	CCO17660.1
Bathy14g00020		Bathycoccus prasinos RCC1105	CCO19653.1
Bathy04g00010		Bathycoccus prasinos RCC1105	CCO16144.1
Bathy15g00720		Bathycoccus prasinos RCC1105	CCO20068.1
Bathy11g03110		Bathycoccus prasinos RCC1105	CCO18691.1
Bathy01g05620		Bathycoccus prasinos RCC1105	CCO14569.1
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