Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); 2-keto-3-deoxynononic acid hydrolase (EC 3.2.1.-); anhydrosialidase (EC 4.2.2.15); 3-deoxy-D-manno-octulosonic-acid hydrolase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (3514); Uniprot accession (686); PDB accession (144); 3D entries (19); cryst (0)
All (3255) Archaea (1) Bacteria (2851) Eukaryota (371) Viruses (32) Structure (19) Characterized (96)
| 1 | 2 | 3 | 4 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01551.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01552.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01553.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01554.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01555.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01556.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01557.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01558.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01559.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01560.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01561.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01562.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01563.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01564.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01565.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01566.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01567.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01568.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01569.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01570.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01571.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01572.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01573.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01574.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01575.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01576.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGI37819.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGI37820.1    
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07400.1 A0PGB4  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07401.1 A0PGB5  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07402.1 A0PGB6  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07403.1 A0PGB7  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07404.1 A0PGB8  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07405.1 A0PGB9  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07406.1 A0PGC0  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07407.1 A0PGC1  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07408.1 A0PGC2  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07409.1 A0PGC3  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07410.1 A0PGC4  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07411.1 A0PGC5  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07412.1 A0PGC6  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07413.1 A0PGC7  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07414.1 A0PGC8  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07415.1 A0PGC9  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07416.1 A0PGD0  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07417.1 A0PGD1  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07418.1 A0PGD2  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07419.1 A0PGD3  
 amastigote surface protein 2 (Asp-2) (partial)   Trypanosoma cruzi BRAZIL AAC47720.1 P90605  
 shed-acute-phase-antigen (SapA)   Trypanosoma cruzi CAI CAA40511.1 Q00773  
 flagellum-associated protein FL-160-3   Trypanosoma cruzi CL CAA50288.1 Q05507  
 P85.1   Trypanosoma cruzi CL AAD13334.1 O61081  
 P85.2   Trypanosoma cruzi CL AAD13335.1 O61082  
 sialidase 85-1.1 3.2.1.18 Trypanosoma cruzi CL AAA30245.1 P18269  
 sialidase 85-1.2 (fragment)   Trypanosoma cruzi CL CAA37618.1 P18270  
 sialidase SA85-1.2 3.2.1.18 Trypanosoma cruzi CL AAA30246.1 Q03625  
 trans-sialidase-like protein   Trypanosoma cruzi CL ABO28970.1 A4GWE6  
 surface antigen (Gp82) (fragment)   Trypanosoma cruzi CL / G AAF02477.1
AAA21303.1
Q26890
Q9U7F3
 
 trans-sialidase (TcTS;Tc00.1047053509495.30) 2.4.1.- Trypanosoma cruzi CL Brener EAN85580.1    
 amastigote surface protein 3 (Asp-3) (partial)   Trypanosoma cruzi CL Brener ACI02313.1 B5U6T8  
 Tcc1j12.1   Trypanosoma cruzi CL BRENER AAL90887.1 Q8T304  
 Tcc1j12.4   Trypanosoma cruzi CL BRENER AAL90890.1 Q8T301  
 Tcc1j12.5   Trypanosoma cruzi CL BRENER AAL90891.1 Q8T300  
 surface antigen PHGST#5   Trypanosoma cruzi CL BRENER AAC79848.2 O96602  
 TcCLB.506331.90 / Tc00.1047053506331.90   Trypanosoma cruzi CL Brener EAN96369.1    
 trans-sialidase (TcTS-12) 2.4.1.- Trypanosoma cruzi CL BRENER ACF17926.1 B3VSM4  
 trans-sialidase (TcTS-15) 2.4.1.- Trypanosoma cruzi CL BRENER ACF17927.1 B3VSM5  
 trans-sialidase (TcTS-24) 2.4.1.- Trypanosoma cruzi CL BRENER ACF17928.1 B3VSM6  
 trans-sialidase (TcTS-46) 2.4.1.- Trypanosoma cruzi CL BRENER ACF17929.1 B3VSM7  
 trans-sialidase (TcTS-49) 2.4.1.- Trypanosoma cruzi CL BRENER ACF17930.1 B3VSM8  
 trans-sialidase, partial (Tsα-1) (fragment)   Trypanosoma cruzi CL Brenner TSA-1 AID66711.1    
 trans-sialidase, partial (Tsα-1) (fragment)   Trypanosoma cruzi CL Brenner TSA-1 AID66712.1    
 surface protein-2   Trypanosoma cruzi CL-BRENER ABQ53588.1 A5JUX3  
 surface protein-2   Trypanosoma cruzi COLOMBIAN ABQ53589.1 A5JUX4  
 trans-sialidase, partial (Tsα-1) (fragment)   Trypanosoma cruzi Esmeraldo cl3 TSA-1 AID66713.1    
 surface glycoprotein GP90, partial   Trypanosoma cruzi G AAM47176.2    
 GP82-related trans-sialidase   Trypanosoma cruzi G ALO20095.1    
 82-kDa surface antigen   Trypanosoma cruzi G AIY32000.2    
 82-kDa surface antigen, partial (fragment)   Trypanosoma cruzi G ALQ10781.1    
 surface antigen GP90, partial   Trypanosoma cruzi G APG55782.1    
 surface protein-2   Trypanosoma cruzi G ABQ53592.1 A5JUX7  
 surface protein-2   Trypanosoma cruzi G ABQ53593.1 A5JUX8  
 stage-specific surface protein (Gp82;SL2)   Trypanosoma cruzi G ABR19835.1
ABR19836.1
AIY31990.1
AIY31992.1
AIY31993.1
AIY31994.1
AIY31995.1
AIY31996.1
AIY31999.1
AIY32000.1
ALQ10780.1
APG55781.1
A9XBF2  
 82-kDa surface antigen, partial (fragment)   Trypanosoma cruzi G AIY31991.1    
 82-kDa surface antigen, partial (fragment)   Trypanosoma cruzi G AIY31997.1    
 82-kDa surface antigen, partial (fragment)   Trypanosoma cruzi G AIY31998.1    
 surface glycoprotein Gp90   Trypanosoma cruzi G (KINETOPLAST) AAM47176.1 Q8M369  
 surface glycoprotein GP90 (fragment)   Trypanosoma cruzi G (KINETOPLAST) AAM47177.1 Q8M368  
 surface glycoprotein GP90 (fragment)   Trypanosoma cruzi G (KINETOPLAST) AAM47178.1 Q8M367  
 glycoprotein 82 kDa (gp82 subfamily A1) (fragment)   Trypanosoma cruzi H1 BAF74641.1 A7BI39  
 glycoprotein 82 kDa (gp82 subfamily A2) (fragment)   Trypanosoma cruzi H1 BAF74642.1 A7BI40  
 glycoprotein 82 kDa (gp82 subfamily C1) (fragment)   Trypanosoma cruzi H1 BAF74652.1 A7BI50  
 glycoprotein 82 kDa (gp82 subfamily A3) (fragment)   Trypanosoma cruzi H20 BAF74643.1 A7BI41  
 glycoprotein 82 kDa (gp82 subfamily A4) (fragment)   Trypanosoma cruzi H20 BAF74644.1 A7BI42  
 glycoprotein 82 kDa (gp82 subfamily C2) (fragment)   Trypanosoma cruzi H20 BAF74653.1 A7BI51  
 trans-sialidase, partial   Trypanosoma cruzi marinkellei TCC426 AHI17183.1    
 trans-sialidase, partial   Trypanosoma cruzi marinkellei TCC426 AHI17184.1    
 glycoprotein 82 kDa (gp82 subfamily A5) (fragment)   Trypanosoma cruzi PERU1 BAF74645.1 A7BI42  
 glycoprotein 82 kDa (gp82 subfamily B1) (fragment)   Trypanosoma cruzi PERU1 BAF74648.1 A7BI46  
 glycoprotein 82 kDa (gp82 subfamily B2) (fragment)   Trypanosoma cruzi PERU1 BAF74649.1 A7BI47  
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