Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (6329); Uniprot accession (681); PDB accession (152); 3D entries (21); cryst (0)
All (6088) Archaea (1) Bacteria (5613) Eukaryota (431) Viruses (37) unclassified (6) Structure (21) Characterized (97)
| 1 | 2 | 3 | 4 | 5 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 trans-sialidase (TS) (fragment)   Trypanosoma cruzi ACV74323.1 C9DS89  
 trans-sialidase (TS) (fragment)   Trypanosoma cruzi ACV74324.1 C9DS90  
 trans-sialidase (TS) (fragment)   Trypanosoma cruzi ACV74325.1 C9DS91  
 trans-sialidase (TS) (fragment)   Trypanosoma cruzi ACV74326.1 C9DS92  
 trans-sialidase (TS) (fragment)   Trypanosoma cruzi ACV74327.1 C9DS93  
 trans-sialidase (TS) (fragment)   Trypanosoma cruzi ACV74328.1 C9DS94  
 trans-sialidase (TS) (fragment)   Trypanosoma cruzi ACV74329.1 C9DS95  
 trans-sialidase (TS) (fragment)   Trypanosoma cruzi ACV74330.1 C9DS96  
 trans-sialidase (TS) (fragment)   Trypanosoma cruzi ACV74332.1 C9DS98  
 trans-sialidase (TS) (fragment)   Trypanosoma cruzi ACV74333.1 C9DS99  
 trans-sialidase (TS) (fragment)   Trypanosoma cruzi ACV74334.1 C9DSA0  
 surface protein-2 (ASP-2)   Trypanosoma cruzi AAO84045.1
AAO84046.1
Q86DL6
Q86DL7
 
 surface protein-2 (Asp-2)   Trypanosoma cruzi AAO84044.1 Q86DL8  
 trans-sialidase, partial (fragment)   Trypanosoma cruzi AWG47886.1
AWG47887.1
AWG47888.1
AWG47889.1
AWG47890.1
AWG47891.1
AWG47892.1
AWG47893.1
AWG47894.1
AWG47895.1
AWG47896.1
AWG47897.1
AWG47898.1
AWG47899.1
AWG47900.1
AWG47901.1
AWG47902.1
AWG47903.1
AWG47904.1
AWG47905.1
AWG47906.1
AWG47907.1
AWG47908.1
AWG47909.1
AWG47910.1
AWG47911.1
AWG47912.1
AWG47913.1
AWG47914.1
AWG47915.1
AWG47916.1
AWG47917.1
AWG47918.1
AWG47919.1
AWG47920.1
AWG47921.1
AWG47922.1
AWG47923.1
AWG47924.1
AWG47925.1
AWG47926.1
AWG47927.1
AWG47928.1
AWG47929.1
AWG47930.1
AWG47931.1
AWG47932.1
AWG47933.1
AWG47934.1
AWG47935.1
AWG47936.1
AWG47937.1
AWG47938.1
AWG47939.1
AWG47940.1
AWG47941.1
AWG47942.1
AWG47943.1
   
 Gp-85 (fragment)   Trypanosoma cruzi AAQ74647.1 Q6WAZ1  
 Sp1   Trypanosoma cruzi AAQ74641.1 Q6WAZ7  
 trypomastigote ligand   Trypanosoma cruzi AAS00641.1 Q6R526  
 trans-sialidase (Sp1) (fragment)   Trypanosoma cruzi ADX23545.1    
 trans-sialidase (Sp2) (fragment)   Trypanosoma cruzi ADX23547.1    
 82-kDa surface antigen (fragment)   Trypanosoma cruzi AEM66559.1    
 surface glycoprotein Tc-85/35 (fragment)   Trypanosoma cruzi AAP32144.1 Q2VYD4  
 surface glycoprotein Tc-85/10 (fragment)   Trypanosoma cruzi AAP32145.1 Q2VYD3  
 surface glycoprotein Tc-85/11 (fragment)   Trypanosoma cruzi AAP32146.1 Q2VYD2  
 surface glycoprotein Tc-85/13 (fragment)   Trypanosoma cruzi AAP32147.1 Q2VYD1  
 surface glycoprotein Tc-85/16 (fragment)   Trypanosoma cruzi AAP32148.1 Q2VYD0  
 surface glycoprotein Tc-85/19 (fragment)   Trypanosoma cruzi AAP32149.1 Q2VYC9  
 surface glycoprotein Tc-85/20 (fragment)   Trypanosoma cruzi AAP32150.1 Q2VYC8  
 surface glycoprotein Tc-85/32 (fragment)   Trypanosoma cruzi AAP32151.1 Q2VYC7  
 surface glycoprotein Tc85-45 (fragment)   Trypanosoma cruzi AAO62997.1 Q2VYD6  
 surface glycoprotein Tc85-26 (fragment)   Trypanosoma cruzi AAO62998.1 Q2VYD5  
 complement regulatory protein   Trypanosoma cruzi AAB49414.1 Q26889  
 surface antigen Gp85   Trypanosoma cruzi AAA30150.1
AAA03205.1
Q03877  
 surface glycoprotein   Trypanosoma cruzi AAA18827.1 Q08661  
 surface glycoprotein   Trypanosoma cruzi AAD10618.1 Q26851  
 surface glycoprotein   Trypanosoma cruzi AAD10619.1 Q26852  
 surface glycoprotein (Tsα-E3)   Trypanosoma cruzi AAD10620.1 Q26853  
 surface glycoprotein (Tc85-11)   Trypanosoma cruzi AAD13347.1 O77209  
 surface protein   Trypanosoma cruzi BAA31361.1
BAA74524.1
O76141  
 surface protein 1   Trypanosoma cruzi AAB18265.1 Q94798  
 TCNA   Trypanosoma cruzi AAA30255.1
ABH92708.1
P23253  
 trans-sialidase 2.4.1.- Trypanosoma cruzi AAC98544.1
BAD99565.1
BAD99566.1
Q26850  
 trans-sialidase 2.4.1.- Trypanosoma cruzi AAO30669.1
AAT21541.1
ABH92705.1
BAA09334.1
Q26964  
 trans-sialidase (TcTS) 2.4.1.- Trypanosoma cruzi AAA66352.1
AAO30670.1
AAT21542.1
Q26966 1MR5[A]
1MS0[A,B]
1MS1[A,B]
1MS3[A,B]
1MS4[A,B]
1MS5[A,B]
1MS8[A,B]
1MS9[A,B]
1S0I[A]
1S0J[A]
1S0K[A]
2AH2[A]
3B69[A]
3OPZ[A,B,C,M]
3PJQ[A]
 trans-sialidase (fragment)   Trypanosoma cruzi AAC47166.1 Q26887  
 trans-sialidase (inactive)   Trypanosoma cruzi BAA09333.1
AAA99442.1
AAA99443.1
ABH92706.1
Q26963
Q26967
Q26968
 
 trans-sialidase homolog   Trypanosoma cruzi BAA09335.1 Q26965  
 trans-sialidase TSA-T20A (fragment)   Trypanosoma cruzi AAB36926.1 P90604  
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01541.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01542.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01543.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01544.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01545.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01546.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01547.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01548.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01549.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01550.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01551.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01552.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01553.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01554.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01555.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01556.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01557.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01558.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01559.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01560.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01561.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01562.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01563.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01564.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01565.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01566.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01567.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01568.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01569.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01570.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01571.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01572.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01573.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01574.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01575.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGA01576.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGI37819.1    
 trans-sialidase, partial (TS) (fragment)   Trypanosoma cruzi AGI37820.1    
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07400.1 A0PGB4  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07401.1 A0PGB5  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07402.1 A0PGB6  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07403.1 A0PGB7  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07404.1 A0PGB8  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07405.1 A0PGB9  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07406.1 A0PGC0  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07407.1 A0PGC1  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07408.1 A0PGC2  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07409.1 A0PGC3  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07410.1 A0PGC4  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07411.1 A0PGC5  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07412.1 A0PGC6  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07413.1 A0PGC7  
 85 kDa surface glycoprotein (fragment)   Trypanosoma cruzi AAT07414.1 A0PGC8  
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