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Glycoside Hydrolase Family 33

Activities in FamilyTrans-sialidase (EC 2.4.1.-);
2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-);
Kdo hydrolase (EC 3.2.1.124);
Exo-α-sialidase (EC 3.2.1.18);
Anhydrosialidase (EC 4.2.2.15);
Mechanism Retaining e
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesCAZypedia; HOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (11188); Uniprot accession (128); PDB accession (186); 3D entries (29); cryst (0)
Summary
Download GH33 (11185) Taxonomic display Structure (29) Characterized (97)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 233672   Penicillium solitum ITEM 18327 v1.0 (Psol18327_1)      
 2185   Penicillium subrubescens (Pensub1)      
 4635   Penicillium subrubescens (Pensub1)      
 9876   Penicillium vulpinum IBT 29486 (Penvul1)      
 4422   Penicillium vulpinum IBT 29486 (Penvul1)      
 6709   Pestalotiopsis fici W106-1 (Pesfi1)      
 517515   Pestalotiopsis sp. NC0098 v1.0 (Pestal1)      
 182F10 (fragment)   Philodina roseola ACD54789.1    
 MPIPNATIZW_LOCUS15458   Pipistrellus nathusii CAK6447152.1    
 MPIPNATIZW_LOCUS17284   Pipistrellus nathusii CAK6448978.1    
 MPIPNATIZW_LOCUS16657   Pipistrellus nathusii CAK6448351.1    
 MPIPNATIZW_LOCUS16732   Pipistrellus nathusii CAK6448426.1    
 279862   Plectosphaerella cucumerina RP01 v1.0 (Plecuc1)      
 8409   Pochonia chlamydosporia 170 (Pocchl1)      
 PODLI_1B025591   Podarcis lilfordi CAI5775455.1    
 PODLI_1B027554   Podarcis lilfordi CAI5768104.1    
 PODLI_1B040411   Podarcis lilfordi CAI5773570.1    
 PODLI_1B014885   Podarcis lilfordi CAI5773573.1    
 PODLI_1B003704   Podarcis lilfordi CAI5773571.1    
 496520   Polyplosphaeria fusca CBS 125425 v1 (Polfu1)      
 DKFZp468G0924 (probable fragment)   Pongo abelii CAH89766.1    
 DKFZp469E1532   Pongo abelii CAH89635.1    
 DKFZp468K0928   Pongo abelii CAH91256.1    
 DKFZp459L0538 (fragment)   Pongo abelii CAH91396.1    
 ORF (fragment)   Potamotrygon motoro QFF91256.1    
 ORF (fragment)   Potamotrygon motoro QFF91253.1    
 ORF   Potamotrygon motoro QFF91260.1    
 ORF (fragment)   Potamotrygon motoro QFF91259.1    
 ORF   Potamotrygon motoro QFF91252.1    
 ORF   Potamotrygon motoro QFF91255.1    
 ORF   Potamotrygon motoro QFF91258.1    
 ORF   Potamotrygon motoro QFF91251.1    
 ORF (fragment)   Potamotrygon motoro QFF91254.1    
 ORF (fragment)   Potamotrygon motoro QFF91261.1    
 ORF (fragment)   Potamotrygon motoro QFF91257.1    
 Prudu_000787   Prunus dulcis BBG92919.1    
 5247   Pseudogymnoascus destructans 20631-21 (Pseudest1)      
 428964   Pseudomassariella vexata CBS 129021 v1.0 (Pseve2)      
 sialidase 1 (Neu1)   Pseudorca crassidens BBG43806.1    
 1843   Purpureocillium lilacinum PLFJ-1 (Purli1)      
 JDV02_009141   Purpureocillium takamizusanense PT3 UNI23311.1    
 PoMZ_05120   Pyricularia oryzae QBZ63439.1    
 2360   Magnaporthe oryzae 70-15 v3.0 (Magor1)      
 MRATA1EN1_LOCUS17536   Rangifer tarandus platyrhyncus CAI9168574.1    
 MRATA1EN1_LOCUS1666   Rangifer tarandus platyrhyncus CAI9152704.1    
 MRATA1EN1_LOCUS2281   Rangifer tarandus platyrhyncus CAI9153319.1    
 MRATA1EN1_LOCUS1484   Rangifer tarandus platyrhyncus CAI9152522.1    
 sialidase 3.2.1.18 Rattus norvegicus BAA03805.1
AAH91154.1
BAA09169.1
NP_058826.1		 A0A0G2JZS7
Q5BK97
Q64627		  
 sialidase (Neu1)   Rattus norvegicus BAB21443.1
AAI00640.1
CAE83976.1
NP_113710.1		    
 sialidase (Neu3)   Rattus norvegicus BAB32440.1
AAI00626.1
NP_446462.1		    
 1413   Rhizoctonia solani AG-3 Rhs1AP (Rhisol1)      
 3226   Rhizoctonia solani AG-8 WAC10335 (Rhisola1)      
 1289071   Russula earlei BPL698 v1.0 (Rusear1)      
 ORF   Saccoglossus kowalevskii ALR88583.1    
 ORF   Saccoglossus kowalevskii ALR88582.1    
 SMAX5B_013492   Scophthalmus maximus AWO98938.1    
 SMAX5B_004198   Scophthalmus maximus AWP00131.1    
 SMAX5B_015811 (fragment)   Scophthalmus maximus AWP21371.1    
 SMAX5B_015811   Scophthalmus maximus AWP21373.1    
 SMAX5B_015811   Scophthalmus maximus AWP21372.1    
 84263   Selaginella moellendorffii (Selmo1)      
 sialidase neu4   Seriola dumerili BBG56813.1    
 sialidase-3a (Neu3A)   Seriola dumerili BCL01290.1    
 107440   Setosphaeria turcica Et28A v2.0 (Settu3)      
 MTR67_052974   Solanum verrucosum WMV59589.1    
 AYBTSS11_LOCUS12200   Sphenostylis stenocarpa CAJ1944955.1    
 AYBTSS11_LOCUS12199   Sphenostylis stenocarpa CAJ1944953.1    
 SI7747_12015219   Spirodela intermedia CAA2629581.1    
 SI8410_12016412   Spirodela intermedia CAA7405734.1    
 474904   Sporormia fimetaria v1 (Spofi1)      
 357174   Stachybotrys elegans LAHC-LSPK-M15 v1.0 (Stael1)      
 462168   Stachybotrys elegans LAHC-LSPK-M15 v1.0 (Stael1)      
 292409   Stagonospora sp. SRC1lsM3a v1.0 (Stasp1)      
 SBAB-707F1.8-001 (Neu1)   Sus scrofa CAN87707.1
ABX82833.1		    
 ORF   Tachysurus fulvidraco WPX93418.1    
 Neu1   Takifugu rubripes ABQ62949.1    
 Neu3   Takifugu rubripes ABQ62950.1    
 Neu4   Takifugu rubripes ABQ62951.1    
 TRUGW13939_10322   Talaromyces rugulosus W13939 QKX63153.1    
 TRUGW13939_09421   Talaromyces rugulosus W13939 QKX62262.1    
 696847   Thanatephorus cucumeris PT424 v1.0 (Thacu1)      
 QQP08_025317   Theobroma cacao isolate Sca6 WRX32830.1    
 QQP08_025319   Theobroma cacao isolate Sca6 WRX32832.1    
 MYCTH_2306764   Thermothelomyces thermophilus ATCC 42464 AEO58960.1    
 TAV2_ LOCUS 19467   Thlaspi arvense CAH2069604.1    
 606041   Trematosphaeria pertusa CBS 122368 v1 (Trepe1)      
 MOV77_012599   Trichomonas stableri BTPI-3 WGY93084.1    
 MOV77_024690   Trichomonas stableri BTPI-3 WGZ01693.1    
 MOV77_029238   Trichomonas stableri BTPI-3 WGZ05452.1    
 1010   Trichophyton rubrum CBS 118892 (Triru1)      
 KDNase 3.2.1.- Trichophyton rubrum CMCC(F)T1i OAL63013.1 A0A178EUH2 7P1Q[A]
7P1R[A,B,C,D]
7P1S[A,B,C,D]
7P1U[A,B]
7P1V[A,B,C,D]
 1573   Trichophyton verrucosum HKI 0517 (Triver1)      
 CAMPLR22A2D_LOCUS2140   Triticum aestivum SPT17530.1    
 putative trans-sialidase B38p   Trypanosoma brucei AAG32055.1    
 Tsi1   Trypanosoma brucei ANTAT 1.1 AAG09432.1    
 Tb927.2.5280   Trypanosoma brucei brucei TREU927 AAQ15986.1
AAX80006.1		    
 2,3-trans-sialidase (TbSA C2;Tb927.8.7350) 2.4.1.- Trypanosoma brucei brucei TREU927 AAX69221.1 Q57YT7  
 Tb927.8.7340   Trypanosoma brucei brucei TREU927 AAX69223.1    
 Tb927.7.6830 (fragment)   Trypanosoma brucei brucei TREU927 AAX69473.1    
 Tb927.7.6850   Trypanosoma brucei brucei TREU927 AAX69677.1    
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