Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (5098); Uniprot accession (686); PDB accession (146); 3D entries (19); cryst (0)
All (4861) Archaea (1) Bacteria (4415) Eukaryota (389) Viruses (34) unclassified (22) Structure (19) Characterized (96)
| 1 | ... | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | ... | 46 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CDB402_0252   Corynebacterium diphtheriae INCA 402 AEX45563.1    
 CDB402_0452 (NanH)   Corynebacterium diphtheriae INCA 402 AEX45763.1    
 trans-sialidase (NanH;NanA) 2.4.1.- Corynebacterium diphtheriae KCTC 3075 ACS34893.1 C6JSW6  
 sialidase (NanI;NanB)   Corynebacterium diphtheriae KCTC 3075 ACS34894.1 C6JSW7  
 DIP0543   Corynebacterium diphtheriae NCTC 13129 CAE49054.1
NP_938919.1
   
 DIP0330   Corynebacterium diphtheriae NCTC 13129 CAE48837.1
NP_938718.1
   
 ERS451417_00260 (NanI)   Corynebacterium diphtheriae NCTC11397 CKG64847.1    
 ERS451417_00477 (NanH)   Corynebacterium diphtheriae NCTC11397 CKG71642.1    
 NCTC3529_02012 (NanI)   Corynebacterium diphtheriae NCTC3529 VEJ67015.1    
 NCTC3529_02215 (NanH)   Corynebacterium diphtheriae NCTC3529 VEJ67212.1    
 NCTC7838_00130 (NanI)   Corynebacterium diphtheriae NCTC7838 VEJ62914.1    
 NCTC7838_00336 (NanH)   Corynebacterium diphtheriae NCTC7838 VEJ63114.1    
 CDPW8_0344   Corynebacterium diphtheriae PW8 AEX69006.1    
 CDPW8_0542 (NanH)   Corynebacterium diphtheriae PW8 AEX69204.1    
 E4653_01335   Corynebacterium diphtheriae subsp. lausannense CMCNS703 QBZ28802.1    
 E4653_02585   Corynebacterium diphtheriae subsp. lausannense CMCNS703 QBZ28989.1    
 E4651_01760   Corynebacterium diphtheriae TH1526 QBY12475.1    
 E4651_00730   Corynebacterium diphtheriae TH1526 QBY10552.1    
 CDVA01_0230   Corynebacterium diphtheriae VA01 AEX82499.1    
 CDVA01_0429 (NanH)   Corynebacterium diphtheriae VA01 AEX82698.1    
 CEPID_03560   Corynebacterium epidermidicanis DSM 45586 AKK02590.1    
 CGERO_05070 (NanA)   Corynebacterium geronticis W8 AZA11326.1    
 RXN02478   Corynebacterium glutamicum CAC26191.1 Q8NMC8  
 FRXA02513 / RXN02513 (fragment)   Corynebacterium glutamicum CAC26187.1
AAW20926.1
CAC26186.1
CAL31683.1
CAL31684.1
   
 RXA00984 (fragment)   Corynebacterium glutamicum CAC26185.1
CAL31682.1
   
 CGBL_0116740 (NanH) (fragment)   Corynebacterium glutamicum AJ1511 BAV23396.1    
 CGBL_0116750 (NanH) (fragment)   Corynebacterium glutamicum AJ1511 BAV23397.1    
 CGBL_0125870 (NanH)   Corynebacterium glutamicum AJ1511 BAV24278.1    
 cg1756 (NanH)   Corynebacterium glutamicum ATCC 13032 CAF21565.1
BAB98949.1
CCH24715.1
NP_600771.1
Q6M535  
 cg2935 (NanP)   Corynebacterium glutamicum ATCC 13032 BAC00044.1
ABC13268.1
CAF21311.1
CAL31688.1
CCH25780.1
NP_601849.1
Q8NMC8  
 CYL77_13430   Corynebacterium glutamicum ATCC 13032 AUI02045.1    
 BBD29_12965   Corynebacterium glutamicum ATCC 13869 ANU34577.1    
 cgc1_2935 (NanP)   Corynebacterium glutamicum C1 ASW14966.1    
 cgc1_1756 (NanH)   Corynebacterium glutamicum C1 ASW14166.1    
 AC079_13165   Corynebacterium glutamicum CP18 ALP51049.1    
 C0I99_01430   Corynebacterium glutamicum HA AUI02860.1    
 cgp_2935 (NanP)   Corynebacterium glutamicum MB001 AGT06367.1    
 cgp_1756 (NanH)   Corynebacterium glutamicum MB001 AGT05516.1    
 N24_2734 (NanP)   Corynebacterium glutamicum N24 BAU96996.1    
 cgR_1608   Corynebacterium glutamicum R BAF54600.1    
 cgR_2554   Corynebacterium glutamicum R BAF55566.1    
 C624_13025   Corynebacterium glutamicum SCgG1 AGN20172.1    
 C624_08555   Corynebacterium glutamicum SCgG1 AGN19286.1    
 C629_13030   Corynebacterium glutamicum SCgG2 AGN23196.1    
 C629_08565   Corynebacterium glutamicum SCgG2 AGN22311.1    
 B7P23_15235   Corynebacterium glutamicum TQ2223 ARV66138.1    
 B7P23_05095   Corynebacterium glutamicum TQ2223 ARV64311.1    
 APT58_13045   Corynebacterium glutamicum USDA-ARS-USMARC-56828 AMA01077.1    
 BSP99_13380   Corynebacterium glutamicum XV APT08329.1    
 A3654_08265   Corynebacterium glutamicum YI ANE08356.1    
 C627_08425 (fragment)   Corynebacterium glutamicum ZL-6 ANR65645.1    
 C627_13015   Corynebacterium glutamicum ZL-6 ANR66531.1    
 C627_08430 (fragment)   Corynebacterium glutamicum ZL-6 ANR65646.1    
 ckrop_1872 (NanI)   Corynebacterium kroppenstedtii DSM 44385 ACR18588.1 C4LL83  
 NCTC11138_01978 (Nanh_1) (fragment)   Corynebacterium kutscheri NCTC11138 VEH10988.1    
 NCTC11138_01979 (Nanh_2) (fragment)   Corynebacterium kutscheri NCTC11138 VEH10989.1    
 NCTC3655_01301 (Nanh_2) (fragment)   Corynebacterium kutscheri NCTC3655 VEH80532.1    
 NCTC3655_01300 (Nanh_1) (fragment)   Corynebacterium kutscheri NCTC3655 VEH80531.1    
 NCTC3655_01302 (Nanh_3) (fragment)   Corynebacterium kutscheri NCTC3655 VEH80533.1    
 NCTC949_00323 (NanH)   Corynebacterium kutscheri NCTC949 VEH04891.1    
 CMUST_11800   Corynebacterium mustelae DSM 45274 AKK06671.1    
 CMUST_04910   Corynebacterium mustelae DSM 45274 AKK05320.1    
 CPELA_06120 (NanA)   Corynebacterium pelargi 136/3 QAU52491.1    
 CPHO_04675   Corynebacterium phocae M408/89/1 APT92300.1    
 CPPEL_06340 (NanA)   Corynebacterium pseudopelargi 812CH AZA09383.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis 04MAT QBI74461.1    
 Cp1002_0387   Corynebacterium pseudotuberculosis 1002 ADL20287.1 D9Q6J2  
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis 1002B ALM77000.1    
 Cp12C_0413 (NanH)   Corynebacterium pseudotuberculosis 12C AKJ55057.1    
 Cp226_0402 (NanH)   Corynebacterium pseudotuberculosis 226 AKC73144.1    
 Cp258_0396 (NanH)   Corynebacterium pseudotuberculosis 258 AJF93848.1    
 Cp262_0396 (NanH)   Corynebacterium pseudotuberculosis 262 AKP08063.2    
 Cp267_0402 (NanH)   Corynebacterium pseudotuberculosis 267 AFH51310.1    
 Cp29156_0391 (NanH)   Corynebacterium pseudotuberculosis 29156 AKI58795.1    
 Cp3995_0391 (NanH)   Corynebacterium pseudotuberculosis 3/99-5 AEX38862.1    
 Cp31_0399 (NanH)   Corynebacterium pseudotuberculosis 31 AKN59634.1    
 A4R72_02270   Corynebacterium pseudotuberculosis 32 APB10365.1    
 A4R71_02285   Corynebacterium pseudotuberculosis 33 APB12413.1    
 A4R69_02280   Corynebacterium pseudotuberculosis 34 APB28708.1    
 A4R68_02280   Corynebacterium pseudotuberculosis 35 APB14459.1    
 A4R67_02275   Corynebacterium pseudotuberculosis 36 APB16504.1    
 A4R66_02280   Corynebacterium pseudotuberculosis 38 APB18553.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis 38MAT QBI72361.1    
 A4R65_02275   Corynebacterium pseudotuberculosis 39 APB20594.1    
 Cp4202_0383 (NanH)   Corynebacterium pseudotuberculosis 42/02-A AEP69653.1    
 A4R64_02065   Corynebacterium pseudotuberculosis 43 APB22605.1    
 A4R63_02065   Corynebacterium pseudotuberculosis 46 APB24617.1    
 A4R62_02280   Corynebacterium pseudotuberculosis 48 APB26663.1    
 CPTA_00924   Corynebacterium pseudotuberculosis 48252 AIG06753.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis 87MAT QBB98857.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis 99MAT QBF70839.1    
 CpATCC19410_0424 (NanH)   Corynebacterium pseudotuberculosis ATCC 19410 ARS59917.1    
 CpC231_0390   Corynebacterium pseudotuberculosis C231 ADL09880.1 D9QEF7  
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis Cap1C QBS28731.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis Cap1R QBG76659.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis Cap1W AZN19281.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis CAP3W AUY55601.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis Cap4W QCL06097.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis Cap5W QCL03985.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis Cap8W QBG65326.1    
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