Activities in Family	Trans-sialidase (EC 2.4.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-); Kdo hydrolase (EC 3.2.1.124); Exo-α-sialidase (EC 3.2.1.18); Anhydrosialidase (EC 4.2.2.15);
Mechanism	Retaining e
Clan	GH-E
3D Structure Status	6-fold β-propeller
Catalytic Nucleophile/Base	Tyr+Glu
Catalytic Proton Donor	Not known
External resources	CAZypedia; HOMSTRAD;
Commercial Enzyme Provider(s)	MEGAZYME;
Statistics	GenBank accession (11188); Uniprot accession (128); PDB accession (186); 3D entries (29); cryst (0)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
NtRootA4_03660		Arthrobacter sp. NtRootA4	BCW13387.1
NtRootA4_32540		Arthrobacter sp. NtRootA4	BCW16275.1
NtRootA9_33180		Arthrobacter sp. NtRootA9	BCW20610.1
NtRootA9_33190		Arthrobacter sp. NtRootA9	BCW20611.1
NtRootA9_11190		Arthrobacter sp. NtRootA9	BCW18411.1
NtRootC45_05900		Arthrobacter sp. NtRootC45	BCW25990.1
NtRootC45_34780		Arthrobacter sp. NtRootC45	BCW28878.1
NtRootC7_05900		Arthrobacter sp. NtRootC7	BCW21723.1
NtRootC7_34740		Arthrobacter sp. NtRootC7	BCW24607.1
NtRootD5_34790		Arthrobacter sp. NtRootD5	BCW33148.1
NtRootD5_05910		Arthrobacter sp. NtRootD5	BCW30260.1
ART_3011		Arthrobacter sp. PAMC 25486	AIY02610.1
ART_2421		Arthrobacter sp. PAMC 25486	AIY02020.1
KY499_13980		Arthrobacter sp. PAMC25284	QYF89227.1
KY499_10460		Arthrobacter sp. PAMC25284	QYF88670.1
E5206_02800		Arthrobacter sp. PAMC25564	QCB95995.1
CFN17_11605		Arthrobacter sp. PM3	AXJ10195.1
BWQ92_09865		Arthrobacter sp. QXT-31	APX01975.1
ARUE_c36650 (Neda2)		Arthrobacter sp. Rue61a	AFR30544.1
ARUE_c06020 (Neda1)		Arthrobacter sp. Rue61a	AFR27537.1
StoSoilA2_05920		Arthrobacter sp. StoSoilA2	BCW34536.1
StoSoilB13_46200		Arthrobacter sp. StoSoilB13	BCW52278.1
StoSoilB20_37040		Arthrobacter sp. StoSoilB20	BCW60357.1
StoSoilB20_06730		Arthrobacter sp. StoSoilB20	BCW57326.1
StoSoilB22_06180		Arthrobacter sp. StoSoilB22	BCW61645.1
StoSoilB22_35600		Arthrobacter sp. StoSoilB22	BCW64587.1
StoSoilB3_35340		Arthrobacter sp. StoSoilB3	BCW41999.1
StoSoilB3_05810		Arthrobacter sp. StoSoilB3	BCW39046.1
StoSoilB5_05870		Arthrobacter sp. StoSoilB5	BCW43403.1
IG195_05115		Arthrobacter sp. TES	QOI64462.1
IG195_11000		Arthrobacter sp. TES	QOI62121.1
OIT41_17820		Arthrobacter sp. YA7-1	UYY81135.1
OIT41_04695		Arthrobacter sp. YA7-1	UYY82364.1
ATC04_01630		Arthrobacter sp. YC-RL1	ALQ29368.1
ATC04_04020		Arthrobacter sp. YC-RL1	ALQ29794.1
CGK93_03325		Arthrobacter sp. YN	ASN18844.1
ARZXY2_216		Arthrobacter sp. ZXY-2	AOY69783.1
ARZXY2_3332		Arthrobacter sp. ZXY-2	AOY72846.1
MNQ99_15850		Arthrobacter sulfonylureivorans S4-C24	UNK45387.1
ATHSA_0358		Athalassotoga saccharophila NAS-01	BBJ27489.1
NLZ15_04660		Atlantibacter subterranea LH84-a	UTJ48354.1
NLZ15_10380		Atlantibacter subterranea LH84-a	UTJ49384.1
FF125_06390 (fragment)		Aureibaculum algae 10Alg115	QCX38073.1
FF125_00345		Aureibaculum algae 10Alg115	QCX36955.1
FF125_06385 (fragment)		Aureibaculum algae 10Alg115	QCX38072.1
FF125_09240		Aureibaculum algae 10Alg115	QCX38607.1
Q31a_38240		Aureliella helgolandensis Q31a	QDV25498.1
Q31a_28990		Aureliella helgolandensis Q31a	QDV24579.1
Q31a_20730 (Axe1-6a_1)		Aureliella helgolandensis Q31a	QDV23768.1
Q31a_62070 (Neda_2)		Aureliella helgolandensis Q31a	QDV27814.1
Q31a_37830 (Neda_1)		Aureliella helgolandensis Q31a	QDV25457.1
Q31a_62060		Aureliella helgolandensis Q31a	QDV27813.1
Q31a_10210		Aureliella helgolandensis Q31a	QDV22735.1
L4F91_08455		Avibacterium sp. 20-126	URL01546.1
L4F93_06960		Avibacterium sp. 20-132	URL03331.1
L4F92_09080		Avibacterium sp. 21-595	URL06197.1
NCTC3438_00966 (Nana_2) (fragment)		Avibacterium volantium NCTC3438	VEB23405.1
dqs_0821		Azoarcus olearius DQS4	ANQ83891.1
AzCIB_0589		Azoarcus sp. CIB	AKU10494.1
CJ010_04635 (fragment)		Azoarcus sp. DD4	QDF95879.1
AZC_1976		Azorhizobium caulinodans ORS 571	BAF87974.1
Azoinq_09335		Azospira inquinata Azo-3	QWT48075.1
J8L76_02530		Azospira sp. Azo-2	QWT46603.1
AZSP09_29290		Azospira sp. I09	BBN89906.1
AZOBR_p330018		Azospirillum baldaniorum Sp245	CCD02617.1 AWJ93376.1
D3869_31025		Azospirillum brasilense MTCC4039	QCO19864.1
AZL_b03350		Azospirillum sp. B510	BAI74998.1
TSH58p_32145		Azospirillum sp. TSH58	AWJ88258.1
DEW08_19540		Azospirillum thermophilum	AWK88289.1
BAE_03450		Bacillus aerophilus 232	QAR51893.1
L2D31_15390		Bacillus aerophilus KJ82	UJM27038.1
I4W80_15550		Bacillus altitudinis 1817	QSI43884.1
NIZ93_15410		Bacillus altitudinis 1943r2a1	USY50602.1
J9319_16015		Bacillus altitudinis 6ww6	QTV11862.1
LOS13_05690		Bacillus altitudinis ABT_AC37	WBL52648.1
NM966_15915		Bacillus altitudinis B12	UTV32238.1
RI02_15495		Bacillus altitudinis BA06	QKL23026.1
QNH40_15945		Bacillus altitudinis CES-OCA-19	WHX70978.1
LIS79_15725		Bacillus altitudinis CMF5	USK23726.1
D0438_06225		Bacillus altitudinis Cr2-1	QDZ94545.1
QRD87_16355		Bacillus altitudinis D9_B_49	WJE29603.1
U2873_15985		Bacillus altitudinis F7	WQH38282.1
BPGQ101_16250		Bacillus altitudinis GQYP101	QCU20340.1
V9W61_15505		Bacillus altitudinis JJ1138	WWY40160.1
V9W60_15585		Bacillus altitudinis JJ61	WWY36424.1
MMZ59_15280		Bacillus altitudinis JYY-02	UNG00525.1
NC3_29720		Bacillus altitudinis NC3	BDC60012.1
CSE15_15515		Bacillus altitudinis P-10	ATP95260.1
EQK04_15495		Bacillus altitudinis SCU11	QKL26760.1 QXY97135.1
CFN77_15955		Bacillus altitudinis SGAir0031	ATH73633.1
TM2_29690		Bacillus altitudinis TM2	BDC56300.1
MTX65_15660		Bacillus altitudinis UKM RB11	UOG06992.1
QJS56_09040		Bacillus altitudinis VUMS1	WGV02350.1
JKL50_16130		Bacillus altitudinis ws31	QQX13960.1
G3M80_16780		Bacillus altitudinis ZAP62	QII26175.1
COP00_20425		Bacillus glycinifermentans KBN06P03352	ATH94656.1
MW696_19210		Bacillus glycinifermentans MGMM1	UOY88125.1
neuraminidase		Bacillus licheniformis NCTC8721	VEB20675.1
M8181_17825		Bacillus licheniformis NWMCC0042	WIY55853.1
LXN06_17905		Bacillus licheniformis NWMCC0046	UIN45544.1
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