Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (5124); Uniprot accession (686); PDB accession (146); 3D entries (19); cryst (0)
All (4887) Archaea (1) Bacteria (4436) Eukaryota (390) Viruses (34) unclassified (26) Structure (19) Characterized (96)
| 1 | ... | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | ... | 46 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 A2I91_08040   Erysipelothrix rhusiopathiae GXBY-1 AMS11685.1    
 EEY85_07290   Erysipelothrix rhusiopathiae KC-Sb-R1 AYV35109.1    
 DM789_01555   Erysipelothrix rhusiopathiae ML101 AWU40967.1    
 NCTC8163_00998 (Nana_2)   Erysipelothrix rhusiopathiae NCTC8163 VEH83914.1    
 neuraminidase (Nanh.1)   Erysipelothrix rhusiopathiae str. Fujisawa BAK31357.1    
 neuraminidase   Erysipelothrix rhusiopathiae SY1027 AGN25301.1    
 BC346_07560   Erysipelothrix rhusiopathiae WH13013 AOO68185.1    
 CRT29_03575   Escherichia coli 2/0 AZH63940.1    
 CNQ55_18330   Escherichia coli 317 ATB79324.1    
 E4311_07060   Escherichia coli 382634_2f QCD73267.1    
 CRT34_03575   Escherichia coli 4/0 AZH58531.1    
 CRT35_03575   Escherichia coli 4/1-1 AZH53270.1    
 CRT43_03610   Escherichia coli 4/4 AZH37899.1    
 ECP_0693   Escherichia coli 536 ABG68721.1 Q0TK10  
 DNNLJILF_03926   Escherichia coli 81009 ART45114.1    
 ECABU_c07260   Escherichia coli ABU 83972 ADN45309.1 E1PBY9  
 L282_3503   Escherichia coli APEC IMT5155 AJB38462.1    
 APECO1_1391   Escherichia coli APEC O1 ABJ00080.1 A1A8U0  
 APECO18_22060   Escherichia coli APEC O18 AKK36639.1    
 AM344_26175   Escherichia coli AR_0017 ATY21957.1    
 AM437_12870   Escherichia coli AR_0058 ARX25195.1    
 AM460_22970   Escherichia coli AR_0081 AVN40800.1    
 AM465_23230   Escherichia coli AR_0086 AXZ04399.1    
 AM468_04010   Escherichia coli AR_0089 AXZ79313.1    
 AM483_16545   Escherichia coli AR_0104 ARA65015.1    
 CSC38_0410   Escherichia coli AR_451 AWZ79401.1    
 DR76_4325   Escherichia coli ATCC 25922 AIL17655.1    
 CHI19_10720   Escherichia coli ATCC 700415 AXV11761.1    
 CDW44_03945   Escherichia coli BH100 ATV07895.1    
 BH100B_00737   Escherichia coli BH100 AUF89776.1    
 BH100L_00720   Escherichia coli BH100L AUQ36351.1    
 BH100N_00713   Escherichia coli BH100N AUN89175.1    
 ETE52_10770   Escherichia coli BR14-DEC QAU82116.1    
 ETE54_21110   Escherichia coli BR43-DEC QAV67840.1    
 C7H11_16125   Escherichia coli C4435 AZU43528.1    
 AVR67_03670   Escherichia coli CD306 ALX51398.1    
 c0759   Escherichia coli CFT073 AAN79232.1    
 BWI82_23885   Escherichia coli Combat2C1 AUY73107.1    
 RG41_12390   Escherichia coli D8 APK34624.1    
 DLJ63_16070   Escherichia coli DA33135 AWO26186.1    
 EAS44_08570   Escherichia coli DSM 30083 = JCM 1649 = ATCC 11775 AYO72172.1    
 C2U19_18015   Escherichia coli E41-1 AWR75018.1    
 WM90_11005   Escherichia coli Eco889 ANK52310.1    
 BE937_17880   Escherichia coli Ecol_244 AQW18349.1    
 BE964_23315   Escherichia coli Ecol_276 AQV27156.1    
 A4R37_01235   Escherichia coli Ecol_448 AMX38674.1    
 BE966_02005   Escherichia coli Ecol_542 AQV44634.1    
 BE941_20315   Escherichia coli Ecol_656 AQV58608.1    
 A4X18_01505   Escherichia coli Ecol_732 AMX12234.1    
 A4R39_21245   Escherichia coli Ecol_743 AMX32639.1    
 A4R38_20090   Escherichia coli Ecol_745 AMX37300.1    
 BE928_01845   Escherichia coli Ecol_867 AQV60693.1    
 BE932_27000   Escherichia coli Ecol_AZ146 AQV75788.1    
 BE940_27100   Escherichia coli Ecol_AZ153 AQV86751.1    
 BE939_20175   Escherichia coli Ecol_AZ159 AQW03199.1    
 BE946_05895   Escherichia coli Ecol_AZ161 AQW05668.1    
 BE965_02935   Escherichia coli Ecol_AZ162 AQW10297.1    
 WM48_03520   Escherichia coli ECONIH2 ANK31416.1    
 DV870_10090   Escherichia coli Es_ST80_L1_NDM_10_2017 AXH18226.1    
 CXG97_03690   Escherichia coli ExPEC XM AUG63590.1    
 AL502_01420   Escherichia coli FDAARGOS_144 AVF98288.1    
 EGX93_01590   Escherichia coli FDAARGOS_536 AYY91510.1    
 BXO92_16800   Escherichia coli FHI_NMBU_03 AUZ92581.1    
 AVR74_03200   Escherichia coli G749 AML03840.1    
 CCL28_17600   Escherichia coli H105 ASA43768.1    
 C3K24_22840   Escherichia coli HS13-1 AUY46338.1    
 ECOK1_0683   Escherichia coli IHE3034 ADE88188.1 D5CXB4  
 P423_03325   Escherichia coli JJ1886 AGY87139.1    
 AX202_03410   Escherichia coli JJ1887 AMQ50244.1    
 AVR73_03610   Escherichia coli JJ1897 ALX61581.1    
 AVR68_03405   Escherichia coli JJ2434 ALX56544.1    
 BA058_20935   Escherichia coli K-15KW01 ANR85062.1    
 Hypthetical protein   Escherichia coli LF82 CAP75162.1    
 CUB99_05145   Escherichia coli LS4 ATV47332.1    
 DPQ29_17235   Escherichia coli MCJCHV-1 AXG62178.1    
 SY51_03425   Escherichia coli MNCRE44 AJO82553.1    
 MS7163_00695   Escherichia coli MS7163 AVQ75117.1    
 MS8345_00645   Escherichia coli MS8345 AUG92279.1    
 DBZ19_21665   Escherichia coli Mt1B1 AVZ60013.1    
 AVR75_03225   Escherichia coli MVAST0167 AML08797.1    
 ECNA114_0612   Escherichia coli NA114 AEG35434.1    
 NCTC10430_04048   Escherichia coli NCTC10430 VEC34215.1    
 NCTC11151_03371   Escherichia coli NCTC11151 VDY76249.1    
 ERS451419_02931   Escherichia coli NCTC9001 CKH89322.1    
 NCTC9022_03497   Escherichia coli NCTC9022 VED09929.1    
 NCTC9085_03461 (fragment)   Escherichia coli NCTC9085 VDY87669.1    
 NCTC9085_03460 (fragment)   Escherichia coli NCTC9085 VDY87666.1    
 A9Z04_19705   Escherichia coli NGF1 ANJ41629.1    
 ECOLIN_03545   Escherichia coli Nissle 1917 AID77718.1
AXY48205.1
   
 EUJ32_03705   Escherichia coli NissleGFP_pZE21 QAY38382.1    
 NMECO18_30095   Escherichia coli NMEC O18 AKK46306.1    
 B0908_03375   Escherichia coli NU14 AQX95758.1    
 BQ9550_0564   Escherichia coli O127:H6 SNU22541.1    
 BQ9544_0564   Escherichia coli O127:H6 SLM05628.1    
 E2348_C_0564   Escherichia coli O127:H6 str. E2348/69 CAS08112.1 B7UKV4  
 C7X15_08525   Escherichia coli O18:H1 CFSAN067215 QBZ07327.1    
 WLH_04761   Escherichia coli O25b:H4 ANK06022.1    
 EC958_0791   Escherichia coli O25b:H4-ST131 EC958 CDN81044.1    
 NRG857_03035   Escherichia coli O83:H1 str. NRG 857C ADR26038.1 E4P9F6  
 PA45B_0952   Escherichia coli PA45B ASW58703.1    
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