Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); 2-keto-3-deoxynononic acid hydrolase (EC 3.2.1.-); anhydrosialidase (EC 4.2.2.15); 3-deoxy-D-manno-octulosonic-acid hydrolase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (3514); Uniprot accession (686); PDB accession (144); 3D entries (19); cryst (0)
All (3255) Archaea (1) Bacteria (2851) Eukaryota (371) Viruses (32) Structure (19) Characterized (96)
| 1 | ... | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ... | 30 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ALW22_07885   Cutibacterium acnes PA_30_2_L1 ALT33417.1    
 ALW22_03515   Cutibacterium acnes PA_30_2_L1 ALT32699.1    
 CA2015_2379   Cyclobacterium amurskyense KCTC 12363 AKP51795.1    
 neuraminidase   Cyclobacterium amurskyense KCTC 12363 AKP51429.1    
 CA2015_2865   Cyclobacterium amurskyense KCTC 12363 AKP52272.1    
 CA2015_2378   Cyclobacterium amurskyense KCTC 12363 AKP51794.1    
 CA2015_3736   Cyclobacterium amurskyense KCTC 12363 AKP53111.1    
 CA2015_4257   Cyclobacterium amurskyense KCTC 12363 AKP53604.1    
 CA2015_0731   Cyclobacterium amurskyense KCTC 12363 AKP50194.1    
 CA2015_2005   Cyclobacterium amurskyense KCTC 12363 AKP51431.1    
 CA2015_2363   Cyclobacterium amurskyense KCTC 12363 AKP51779.1    
 CA2015_0291   Cyclobacterium amurskyense KCTC 12363 AKP49771.1    
 CA2015_0288   Cyclobacterium amurskyense KCTC 12363 AKP49768.1    
 CA2015_2376   Cyclobacterium amurskyense KCTC 12363 AKP51792.1    
 CA2015_2380   Cyclobacterium amurskyense KCTC 12363 AKP51796.1    
 CA2015_3667   Cyclobacterium amurskyense KCTC 12363 AKP53044.1    
 Cycma_0384   Cyclobacterium marinum DSM 745 AEL24163.1    
 Cycma_0387   Cyclobacterium marinum DSM 745 AEL24166.1    
 Cycma_2061   Cyclobacterium marinum DSM 745 AEL25808.1    
 Cycma_2063   Cyclobacterium marinum DSM 745 AEL25810.1    
 Cycma_2430   Cyclobacterium marinum DSM 745 AEL26172.1    
 Cycma_2432   Cyclobacterium marinum DSM 745 AEL26174.1    
 Cycma_2433   Cyclobacterium marinum DSM 745 AEL26175.1    
 Cycma_2435   Cyclobacterium marinum DSM 745 AEL26177.1    
 Cycma_3733   Cyclobacterium marinum DSM 745 AEL27445.1    
 Cycma_3805   Cyclobacterium marinum DSM 745 AEL27516.1    
 Cycma_4329   Cyclobacterium marinum DSM 745 AEL28031.1    
 SAMN06298216_1299   Cytophagales bacterium TFI 002 SOE20818.1    
 neuraminidase   Cytophagales bacterium TFI 002 SOE21070.1    
 neuraminidase   Cytophagales bacterium TFI 002 SOE23663.1    
 Daro_0557   Dechloromonas aromatica RCB AAZ45314.1 Q47IL7  
 DTL3_1050   Defluviitoga tunisiensis CEP78354.1    
 DAD186_19940   Dermabacter vaginalis AD1-86 ANP28544.1    
 DAD186_19890   Dermabacter vaginalis AD1-86 ANP28539.1    
 XM25_15840   Devosia sp. H5989 AKR57229.1    
 XM25_05200   Devosia sp. H5989 AKR55212.1    
 Dd1591_0644   Dickeya chrysanthemi Ech1591 ACT05526.1 C6CK10  
 Dda3937_02530   Dickeya dadantii 3937 ADM96302.1 E0SEP9  
 Dda3937_02632   Dickeya dadantii 3937 ADN00006.1 E0SFF3  
 Dd703_0687   Dickeya paradisiaca Ech703 ACS84498.1 C6CA23  
 Dd703_3918   Dickeya paradisiaca Ech703 ACS87671.1 C6C662  
 A4U42_05320   Dickeya solani IPO 2222 ANE74796.1    
 A4U42_08380 (fragment)   Dickeya solani IPO 2222 ANE75352.1    
 W909_16765   Dickeya zeae EC1 AJC67631.1    
 W909_19770   Dickeya zeae EC1 AJC68196.1    
 Dd586_3498   Dickeya zeae Ech586 ACZ78328.1 D2BWH5  
 Dd586_4080   Dickeya zeae Ech586 ACZ78906.1 D2BZN4  
 FH5T_01145   Draconibacterium orientale FH5 AHW58654.1    
 FH5T_13900   Draconibacterium orientale FH5 AHW60355.1    
 Dfer_2148   Dyadobacter fermentans DSM 18053 ACT93371.1 C6VYL6  
 Dfer_2863   Dyadobacter fermentans DSM 18053 ACT94078.1 C6W4H7  
 Dfer_3020   Dyadobacter fermentans DSM 18053 ACT94235.1 C6W5L7  
 neuraminidase   Echinicola vietnamensis DSM 17526 AGA76790.1    
 Echvi_1665   Echinicola vietnamensis DSM 17526 AGA77930.1    
 Echvi_4341   Echinicola vietnamensis DSM 17526 AGA80527.1    
 ETEE_3198 (fragment)   Edwardsiella anguillarum ET080813 AIJ09625.1    
 A9798_10455   Edwardsiella hoshinae ATCC 35051 AOV98594.1    
 ETAC_05915   Edwardsiella piscicida C07-087 AGH73308.1    
 BXA22_01835   Edwardsiella piscicida ETW41 ARD17174.1    
 A9797_06095   Edwardsiella piscicida S11-285 AOP42629.1    
 sialidase NanA   Edwardsiella tarda E01-21 BAV69399.1    
 NanA sialidase   Edwardsiella tarda E22 BAX03532.1    
 NanA sialidase   Edwardsiella tarda E381 BAV59436.1    
 ETAE_1245   Edwardsiella tarda EIB202 ACY84088.1 D0ZFQ6  
 ORF   Edwardsiella tarda ET-1 BAU80413.1    
 ETAF_1161   Edwardsiella tarda FL6-60 ADM41276.1 E0T4S6  
 sialidase (NanA)   Edwardsiella tarda FPC 498 BAP91033.1    
 NanA sialidase   Edwardsiella tarda NUF806 BAV59437.1    
 NanA sialidase   Edwardsiella tarda SU138 BAX36558.1    
 NanA sialidase   Edwardsiella tarda SU226 BAX03533.1    
 sialidase (NanA) 3.2.1.18 Edwardsiella tarda TX01 AFP73415.1    
 BBD33_05820   Elizabethkingia meningoseptica G4076 AQX04795.1    
 BBD35_07650   Elizabethkingia meningoseptica G4120 AQX12256.1    
 B5G46_05815   Elizabethkingia meningoseptica KC1913 AQX46837.1    
 Emtol_2335   Emticicia oligotrophica DSM 17448 AFK03472.1    
 neuraminidase   Emticicia oligotrophica DSM 17448 AFK05157.1    
 neuraminidase   Emticicia oligotrophica DSM 17448 AFK05192.1    
 EZMO1_1737 (fragment)   Endozoicomonas montiporae CL-33 AMO55886.1    
 EZMO1_1736 (fragment)   Endozoicomonas montiporae CL-33 AMO55885.1    
 FA04_32600   Ensifer adhaerens Casida A ANK77378.1    
 OV14_b0333   Ensifer adhaerens OV14 AHK46900.1    
 SJ05684_c15290   Ensifer sojae CCBAU 05684 ASY62971.1    
 AB190_04710   Enterobacter asburiae CAV1043 AKK99904.1    
 A0R60_0918   Enterobacter asburiae ENIPBJ-CG1 AMX05225.1    
 Entas_2142   Enterobacter asburiae LF7a AEN64876.1    
 BFJ73_10280   Enterobacter cloacae AOE95581.1    
 EC036_21440   Enterobacter cloacae GGT036 AIV29791.1    
 BJM06_02266   Enterobacter cloacae M12X01451 ASQ18057.1    
 ECL_02001   Enterobacter cloacae subsp. cloacae ATCC 13047 ADF61553.1 D5C8V6  
 A3UG_11160   Enterobacter cloacae subsp. dissolvens SDM AFM59966.1    
 AKI40_3003   Enterobacter sp. FY-07 AMO49388.1    
 neuraminidase   Enterobacteriaceae bacterium strain FGI 57 AGB78182.1    
 neuraminidase   Enterococcus durans BDGP3 ASV96651.1    
 A4V06_00350   Enterococcus faecalis KB1 ANU71609.1
ASU26373.1
   
 A6B47_00790   Enterococcus faecalis sorialis ARV02485.1    
 sialidase (NanH) 3.2.1.18 Erysipelothrix rhusiopathiae FUJISAWA BAB40435.1 Q9AJR8  
 A2I91_08040   Erysipelothrix rhusiopathiae GXBY-1 AMS11685.1    
 neuraminidase (Nanh.1)   Erysipelothrix rhusiopathiae str. Fujisawa BAK31357.1    
 neuraminidase   Erysipelothrix rhusiopathiae SY1027 AGN25301.1    
 BC346_07560   Erysipelothrix rhusiopathiae WH13013 AOO68185.1    
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