Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (7412); Uniprot accession (682); PDB accession (159); 3D entries (21); cryst (0)
All (7148) Archaea (1) Bacteria (6629) Eukaryota (459) Viruses (53) unclassified (6) Structure (21) Characterized (97)
| 1 | ... | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ... | 68 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 BacF7301_16440   Bacteroides sp. CBA7301 QIU95639.1    
 BacF7301_22335   Bacteroides sp. CBA7301 QIU96716.1    
 H8796_22040   Bacteroides sp. M10 QNL38454.1    
 H8796_16495   Bacteroides sp. M10 QNL37439.1    
 H8796_14115   Bacteroides sp. M10 QNL36993.1    
 H8796_17500   Bacteroides sp. M10 QNL37629.1    
 H8796_22065   Bacteroides sp. M10 QNL38459.1    
 DBK98_000490   Bacteroides sp. PHL 2737 QLK80764.1    
 DBK98_019520   Bacteroides sp. PHL 2737 QLK85135.1    
 DBK98_012945   Bacteroides sp. PHL 2737 QLK82997.1    
 Btheta7330_02628 (NanB)   Bacteroides thetaiotaomicron 7330 ALJ42170.1    
 Btheta7330_02907   Bacteroides thetaiotaomicron 7330 ALJ42444.1    
 FE838_19260   Bacteroides thetaiotaomicron DSM 2079 QMW88034.1    
 FE838_16290   Bacteroides thetaiotaomicron DSM 2079 QMW87502.1    
 BatF92_17160 (fragment)   Bacteroides thetaiotaomicron F9-2 BCA49774.1    
 BatF92_20180   Bacteroides thetaiotaomicron F9-2 BCA50076.1    
 I6G92_14145   Bacteroides thetaiotaomicron FDAARGOS_935 QQA06612.1    
 I6G92_15225   Bacteroides thetaiotaomicron FDAARGOS_935 QQA06813.1    
 bimodular α-1,5-rhamnosidase / α-2,3-KDO-hydrolase (BT1013) 3.2.1.40
3.2.1.-
Bacteroides thetaiotaomicron VPI-5482 AAO76120.1
NP_809926.1
Q8A904  
 sialidase (BtsA;BTSA;BT0455) 3.2.1.18 Bacteroides thetaiotaomicron VPI-5482 AAO75562.1
NP_809368.1
Q8AAK9 4BBW[A]
 I6G58_09945   Bacteroides uniformis FDAARGOS_901 QQA28368.1    
 BVU_1801   Bacteroides vulgatus ATCC 8482 ABR39477.1 A6L1B3  
 BVU_2645   Bacteroides vulgatus ATCC 8482 ABR40297.1 A6L3N3  
 BVU_4143   Bacteroides vulgatus ATCC 8482 ABR41745.1 A6L7T1  
 GFH35_02035   Bacteroides xylanisolvens funn3 QRM97554.1    
 GFH35_21090   Bacteroides xylanisolvens funn3 QRN00952.1    
 GFH35_21110   Bacteroides xylanisolvens funn3 QRN00956.1    
 GFH35_26675   Bacteroides xylanisolvens funn3 QRN01956.1    
 FKZ68_16090   Bacteroides xylanisolvens H207 QDH55645.1    
 FKZ68_15095   Bacteroides xylanisolvens H207 QDH55461.1    
 BXY_44750   Bacteroides xylanisolvens XB1A CBK69352.1 D6D4V8  
 BXY_06360   Bacteroides xylanisolvens XB1A CBK65853.1 D6D758  
 BXY_09340   Bacteroides xylanisolvens XB1A CBK66099.1 D6D7V4  
 BXY_44710   Bacteroides xylanisolvens XB1A CBK69348.1 D6D4V4  
 C4H11_09345   Bacteroides zoogleoformans ATCC 33285 AVM54056.1    
 C4H11_13210   Bacteroides zoogleoformans ATCC 33285 AVM54135.1    
 BARVI_04125   Barnesiella viscericola DSM 18177 AHF12110.1    
 BARVI_05470   Barnesiella viscericola DSM 18177 AHF12313.1    
 A4G13_09150   Basfia succiniciproducens JF4016 QIM69546.1    
 Belba_3245   Belliella baltica DSM 15883 AFL85755.1    
 HF888_05575   Bermanella marisrubri RED65 QIZ83723.1    
 JI75_01895   Berryella intestinalis 68-1-3 AJC11622.1    
 D521_0592   beta proteobacterium CB AGG33161.1    
 Bcav_1436   Beutenbergia cavernae DSM 12333 ACQ79694.1 C5C2K8  
 Bcav_1440   Beutenbergia cavernae DSM 12333 ACQ79698.1 C5C2L2  
 BBBF_1781 (fragment)   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ98988.1    
 BBBF_1780 (fragment)   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ98987.1    
 BBBF_1585   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ98792.1    
 BBBF_1779   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ98986.1    
 RY70_1745   Bifidobacterium bifidum BF3 ALE12069.1    
 RY70_1956   Bifidobacterium bifidum BF3 ALE12272.1    
 BBB_1792 (NedA)   Bifidobacterium bifidum BGN4 AFL05382.1    
 BBB_1574   Bifidobacterium bifidum BGN4 AFL05165.1    
 BBB_1791   Bifidobacterium bifidum BGN4 AFL05381.1    
 JQN90_03385   Bifidobacterium bifidum HN002 QRI58689.1    
 JQN90_02305   Bifidobacterium bifidum HN002 QRI58909.1    
 JQN90_03380   Bifidobacterium bifidum HN002 QRI58688.1    
 exo-α-sialidase (SiaBb2;BBP_0054) 3.2.1.18 Bifidobacterium bifidum JCM 1254 BAK26854.1    
 sialidase (Siabb1)   Bifidobacterium bifidum JCM 1254 BAN14906.1    
 BBJK_01327   Bifidobacterium bifidum LMG 13195 JCM 7004 BBA47922.1    
 BBJK_00867   Bifidobacterium bifidum LMG 13195 JCM 7004 BBA47625.1    
 BBJK_01326   Bifidobacterium bifidum LMG 13195 JCM 7004 BBA47921.1    
 BBNG_01507   Bifidobacterium bifidum NCIMB 41171 EFR50959.1    
 NCTC13001_00443 (Neda_1) (fragment)   Bifidobacterium bifidum NCTC13001 VEG16933.1    
 NCTC13001_00444 (Neda_2) (fragment)   Bifidobacterium bifidum NCTC13001 VEG16935.1    
 NCTC13001_00445 (Neda_3)   Bifidobacterium bifidum NCTC13001 VEG16937.1    
 NCTC13001_00642   Bifidobacterium bifidum NCTC13001 VEG17315.1    
 BBPR_1793   Bifidobacterium bifidum PRL2010 ADP36806.1 E4P0F8  
 BBPR_1794   Bifidobacterium bifidum PRL2010 ADP36807.1 E4P0F9  
 BBPR_1596   Bifidobacterium bifidum PRL2010 ADP36622.1    
 BBIF_1734   Bifidobacterium bifidum S17 ADO53939.1 E3ERD5  
 BBIF_1733   Bifidobacterium bifidum S17 ADO53938.1 E3ERD4  
 BBIF_1538   Bifidobacterium bifidum S17 ADO53743.1    
 CJD48_01115   Bifidobacterium bifidum S6 AXM90913.1    
 CJD48_01110   Bifidobacterium bifidum S6 AXM90912.1    
 CJD48_02230   Bifidobacterium bifidum S6 AXM91086.1    
 BBTM_01956   Bifidobacterium bifidum TMC 3115 BBA56221.1    
 BBTM_01414   Bifidobacterium bifidum TMC 3115 BBA55846.1    
 BBTM_01954   Bifidobacterium bifidum TMC 3115 BBA56220.1    
 BB017W439_0171   Bifidobacterium breve 017W439 AUD94497.1    
 BB082W48_0178   Bifidobacterium breve 082W48 AUD96425.1    
 B12L_0154   Bifidobacterium breve 12L AHJ14956.1    
 BB139W423_0183   Bifidobacterium breve 139W423 AUD98320.1    
 BB180W83_0170   Bifidobacterium breve 180W83 AUE00317.1    
 BB215W447A_0177   Bifidobacterium breve 215W447a AUE02216.1    
 B689b_0150   Bifidobacterium breve 689b AHJ22233.1    
 HMPREF9228_0182   Bifidobacterium breve ACS-071-V-Sch8b AEF27628.1    
 RY69_1874   Bifidobacterium breve BR3 ALE14100.1    
 CNCMI4321_0155   Bifidobacterium breve CNCM I-4321 AUE04412.1    
 DRBB26_0160   Bifidobacterium breve DRBB26 AUD88333.1    
 DRBB27_0166   Bifidobacterium breve DRBB27 AUD90316.1    
 DRBB28_0178   Bifidobacterium breve DRBB28 AUD92408.1    
 DRBB29_0166   Bifidobacterium breve DRBB29 AUE17744.1    
 DRBB30_0156   Bifidobacterium breve DRBB30 AUE19818.1    
 BBBR_0147   Bifidobacterium breve DSM 20213 = JCM 1192 BAQ99185.1    
 EGX97_00835   Bifidobacterium breve FDAARGOS_561 AYZ88197.1    
 GEO35_07445   Bifidobacterium breve IDCC4401 QFV13498.1    
 B7017_0178   Bifidobacterium breve JCM 7017 AHJ16734.1    
 B7019_0163   Bifidobacterium breve JCM 7019 AHJ18498.1    
 D3H49_09595   Bifidobacterium breve JR01 QHP52086.1    
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