Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (6599); Uniprot accession (681); PDB accession (152); 3D entries (21); cryst (0)
All (6360) Archaea (1) Bacteria (5882) Eukaryota (433) Viruses (38) unclassified (6) Structure (21) Characterized (97)
| 1 | ... | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ... | 60 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 BB215W447A_0177   Bifidobacterium breve 215W447a AUE02216.1    
 B689b_0150   Bifidobacterium breve 689b AHJ22233.1    
 HMPREF9228_0182   Bifidobacterium breve ACS-071-V-Sch8b AEF27628.1    
 RY69_1874   Bifidobacterium breve BR3 ALE14100.1    
 CNCMI4321_0155   Bifidobacterium breve CNCM I-4321 AUE04412.1    
 DRBB26_0160   Bifidobacterium breve DRBB26 AUD88333.1    
 DRBB27_0166   Bifidobacterium breve DRBB27 AUD90316.1    
 DRBB28_0178   Bifidobacterium breve DRBB28 AUD92408.1    
 DRBB29_0166   Bifidobacterium breve DRBB29 AUE17744.1    
 DRBB30_0156   Bifidobacterium breve DRBB30 AUE19818.1    
 BBBR_0147   Bifidobacterium breve DSM 20213 = JCM 1192 BAQ99185.1    
 EGX97_00835   Bifidobacterium breve FDAARGOS_561 AYZ88197.1    
 GEO35_07445   Bifidobacterium breve IDCC4401 QFV13498.1    
 B7017_0178   Bifidobacterium breve JCM 7017 AHJ16734.1    
 B7019_0163   Bifidobacterium breve JCM 7019 AHJ18498.1    
 D3H49_09595   Bifidobacterium breve JR01 QHP52086.1    
 GFJ40_00875   Bifidobacterium breve JSRL01 QFZ79614.1    
 BBL520_00915   Bifidobacterium breve LMC520 AQM42305.1    
 EH245_00815   Bifidobacterium breve lw01 AZI15936.1    
 B2258_0149   Bifidobacterium breve NCFB 2258 AHJ20399.1    
 NCTC11815_00150 (NanA)   Bifidobacterium breve NCTC11815 VEG20889.1    
 NRBB01_0148   Bifidobacterium breve NRBB01 AUD66379.1    
 NRBB08_0200   Bifidobacterium breve NRBB08 AUE06537.1    
 NRBB18_0200 (fragment)   Bifidobacterium breve NRBB18 AUE08411.1    
 NRBB18_0199 (fragment)   Bifidobacterium breve NRBB18 AUE08410.1    
 NRBB19_0199   Bifidobacterium breve NRBB19 AUE10285.1    
 NRBB20_0199   Bifidobacterium breve NRBB20 AUE12160.1    
 NRBB27_0199   Bifidobacterium breve NRBB27 AUE14035.1    
 NRBB49_0200   Bifidobacterium breve NRBB49 AUE15907.1    
 NRBB50_0171   Bifidobacterium breve NRBB50 AUD75847.1    
 NRBB51_0152   Bifidobacterium breve NRBB51 AUD80266.1    
 NRBB52_0159   Bifidobacterium breve NRBB52 AUD82235.1    
 NRBB56_0177   Bifidobacterium breve NRBB56 AUD84240.1    
 NRBB57_0189   Bifidobacterium breve NRBB57 AUD86224.1    
 BS27_0176   Bifidobacterium breve S27 AHJ24071.1    
 Bbr_0171   Bifidobacterium breve UCC2003 ABE94880.1    
 SAMN04489749_2042   Bifidobacterium longum Su859 SDO69221.1    
 α-2,6- / α-2,3-sialidase (NanH1;Blon_0646) 3.2.1.- Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 ACJ51753.1 B7GPM3  
 α-2,6- / α-2,3-sialidase (NanH2;Blon_2348) 3.2.1.- Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 ACJ53406.1 B7GNQ0  
 BLIJ_2422   Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 BAJ69999.1    
 BLIJ_0651   Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 BAJ68244.1    
 RY67_485   Bifidobacterium longum subsp. infantis BT1 ALE08548.1    
 RY67_1368   Bifidobacterium longum subsp. infantis BT1 ALE09388.1    
 NCTC11817_02494 (NedA)   Bifidobacterium longum subsp. infantis NCTC11817 VEG44520.1    
 NCTC11817_00667 (NanA)   Bifidobacterium longum subsp. infantis NCTC11817 VEG40809.1    
 BBSC_2316   Bifidobacterium scardovii JCM 12489 = DSM 13734 BAQ32396.1    
 ADH70_012315   Blautia coccoides YL58 ASU31741.1    
 CGC63_00200   Blautia hansenii DSM 20583 ASM68050.1    
 HL650_00135   Blautia producta SCSK QJU17595.1    
 A4V09_13825   Blautia sp. YL58 ANU76745.1
ANU76745.2
   
 BHK69_21185   Bosea vaviloviae Vaf18 AOO82623.1    
 Bfae_08290   Brachybacterium faecium DSM 4810 ACU84683.1 C7M9Y9  
 Bfae_08300   Brachybacterium faecium DSM 4810 ACU84684.1 C7M9Z0  
 CFK41_12805   Brachybacterium ginsengisoli DCY80 ATG55553.1    
 CFK41_12810   Brachybacterium ginsengisoli DCY80 ATG55554.1    
 DWV08_01420   Brachybacterium saurashtrense DSM 23186 AXK44410.1    
 DWV08_01415   Brachybacterium saurashtrense DSM 23186 AXK44409.1    
 BH708_17940   Brachybacterium sp. P6-10-X1 APX34274.1    
 BH708_17935   Brachybacterium sp. P6-10-X1 APX34273.1    
 CFK38_15425   Brachybacterium vulturis VM2412 ATG52765.1    
 CFK38_15420   Brachybacterium vulturis VM2412 ATG52764.1    
 BHAMNSH16_00850   Brachyspira hampsonii NSH-16 ASJ20283.1    
 Bmur_1914   Brachyspira murdochii DSM 12563 ADG71993.1 D5UBC0  
 Bmur_2712   Brachyspira murdochii DSM 12563 ADG72779.1 D5U755  
 neuraminidase   Brachyspira pilosicoli 95/1000 ADK30921.1 D8ICP8  
 neuraminidase   Brachyspira pilosicoli 95/1000 ADK32000.1 D8IFS7  
 neuraminidase   Brachyspira pilosicoli B2904 AFR69790.1    
 neuraminidase   Brachyspira pilosicoli B2904 AFR71142.1    
 neuraminidase   Brachyspira pilosicoli B2904 AFR71144.1    
 BPP43_05040   Brachyspira pilosicoli P43/6/78 AGA66268.1    
 BPP43_05045   Brachyspira pilosicoli P43/6/78 AGA66269.1    
 BPP43_10460   Brachyspira pilosicoli P43/6/78 AGA67264.1    
 neuraminidase   Brachyspira pilosicoli WesB CCG56392.1    
 neuraminidase   Brachyspira pilosicoli WesB CCG56394.1    
 WESB_2245   Brachyspira pilosicoli WesB CCG57707.1    
 XH91_25560   Bradyrhizobium guangzhouense CCBAU 51670 QAU48387.1    
 RN69_34380   Bradyrhizobium japonicum E109 AJA64834.1    
 BKD09_RS37450   Bradyrhizobium japonicum J5 APG14055.1    
 BJS_06052   Bradyrhizobium japonicum SEMIA 5079 AHY52385.1    
 BJ6T_70870   Bradyrhizobium japonicum USDA 6 BAL12336.1    
 BN2626_G22_7129   Bradyrhizobium sp. CUU20713.1    
 G6321_38925   Bradyrhizobium sp. 4(2017) 323S2 QII67062.1    
 BRAD3257_5997   Bradyrhizobium sp. ORS 3257 SPP96922.1    
 Pan97_29160 (Neda_2)   Bremerella volcania Pan97 QDU75874.1    
 Pan97_18740 (NanB)   Bremerella volcania Pan97 QDU74856.1    
 Pan97_03040   Bremerella volcania Pan97 QDU73334.1    
 Pan97_06090 (Neda_1) (fragment)   Bremerella volcania Pan97 QDU73633.1    
 neuraminidase   Brevibacterium aurantiacum SMQ-1418 AZL04464.1    
 CXR27_01845   Brevibacterium aurantiacum SMQ-1420 AZT95890.1    
 sialidase   Brevibacterium casei LHS-SIA ADU02857.1    
 YH66_08205   [Brevibacterium] flavum ATCC 15168 AKF27527.1    
 C628_08520 (fragment)   [Brevibacterium] flavum ZL-1 ANR62642.1    
 C628_08525 (fragment)   [Brevibacterium] flavum ZL-1 ANR62643.1    
 C628_13140   [Brevibacterium] flavum ZL-1 ANR63525.1    
 neuraminidase   Brevibacterium sandarakinum DSM 22082 SDS24506.1    
 BamMC406_5961   Burkholderia ambifaria MC40-6 ACB68397.1 B1Z3T4  
 A2T82_32005   Burkholderia cenocepacia 842 AMU10945.1    
 Bcen_1532   Burkholderia cenocepacia AU 1054 ABF76437.1 Q1BVB8  
 BHQ31_30220   Burkholderia cenocepacia CR318 AQT54433.1    
 FOC28_24720   Burkholderia cenocepacia FDAARGOS_720 QIY42832.1    
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