Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); 2-keto-3-deoxynononic acid hydrolase (EC 3.2.1.-); anhydrosialidase (EC 4.2.2.15); 3-deoxy-D-manno-octulosonic-acid hydrolase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (3810); Uniprot accession (686); PDB accession (146); 3D entries (19); cryst (0)
All (3554) Archaea (1) Bacteria (3148) Eukaryota (372) Viruses (33) Structure (19) Characterized (96)
| 1 | ... | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ... | 33 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CpP54B96_0391 (NanH)   Corynebacterium pseudotuberculosis P54B96 AFF21544.1    
 CpPA01_0371 (NanH)   Corynebacterium pseudotuberculosis PA01 ALR33038.1    
 CpPA02_0369 (NanH)   Corynebacterium pseudotuberculosis PA02 ANK55784.1    
 CpPA04_0393   Corynebacterium pseudotuberculosis PA04 AQL50505.1    
 CpPA05_02990   Corynebacterium pseudotuberculosis PA05 APX35569.1    
 CpPA06_02430   Corynebacterium pseudotuberculosis PA06 APX37410.1    
 CpPA07_0394 (NanH)   Corynebacterium pseudotuberculosis PA07 ATQ64714.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis PA08; A19 ATQ80695.1    
 CpPAT10_0391 (NanH)   Corynebacterium pseudotuberculosis PAT10 AEK91723.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis phoP AQU90003.1    
 AK970_01940   Corynebacterium pseudotuberculosis PO222/4-1 ALU18978.1    
 AN902_01950   Corynebacterium pseudotuberculosis PO269-5 ALF56960.1    
 CpSigmaE_0400 (NanH)   Corynebacterium pseudotuberculosis SigmaE ARB41976.1    
 CpT1_0395 (NanH)   Corynebacterium pseudotuberculosis T1 ANQ78695.1    
 CpVD57_0395 (NanH)   Corynebacterium pseudotuberculosis VD57 AJC13124.1    
 CTEST_12930 (NanI)   Corynebacterium testudinoris DSM 44614 AKK09989.1    
 CULC0102_0481 (NanH)   Corynebacterium ulcerans 0102 BAM26683.1    
 Cul05146_0470 (NanH)   Corynebacterium ulcerans 05146 AIU91055.1    
 Cul131001_0462 (NanH)   Corynebacterium ulcerans 131001 ALD94188.1    
 CUL131002_0438 (NanH)   Corynebacterium ulcerans 131002 AKA95986.1    
 Cul210931_0440 (NanH)   Corynebacterium ulcerans 210931 AIU29801.1    
 Cul210932_0455 (NanH)   Corynebacterium ulcerans 210932 AIT88419.1    
 CULC809_00434 (NanH)   Corynebacterium ulcerans 809 AEG80974.1    
 CULC22_00437 (NanH)   Corynebacterium ulcerans BR-AD22 AEG83155.1    
 CulFRC11_0435 (NanH)   Corynebacterium ulcerans FRC11 AIU32028.1    
 CulFRC58_0499 (NanH)   Corynebacterium ulcerans FRC58 AKN76353.1    
 SAMEA4504038_01773 (NanH)   Corynebacterium ulcerans NCTC7910 SNV12433.1    
 CBE74_02420   Corynebacterium ulcerans PO100/5 ARU45544.1    
 CUTER_01555   Corynebacterium uterequi DSM 45634 AKK10327.1    
 CUTER_03660   Corynebacterium uterequi DSM 45634 AKK10740.1    
 CUTER_01485   Corynebacterium uterequi DSM 45634 AKK10313.1    
 BKK80_26820   Cupriavidus sp. USMAA1020 AOZ09393.1    
 BKK79_32725   Cupriavidus sp. USMAA2-4 AOY96358.1    
 BKK81_29535   Cupriavidus sp. USMAHM13 AOZ03243.1    
 Csp_A02540   Curvibacter putative symbiont of Hydra magnipapillata CBA27491.1 C9Y803  
 AEP_03366   Curvibacter sp. AEP1-3 ARV20288.1    
 VO62_03330   Cutibacterium acnes A1-14 ALU23131.1    
 VO62_07505   Cutibacterium acnes A1-14 ALU23799.1    
 VO62_03325   Cutibacterium acnes A1-14 ALU23130.1    
 RN83_03985   Cutibacterium acnes KCOM 1861 (= ChDC B594) ALD69359.1    
 RN83_03980   Cutibacterium acnes KCOM 1861 (= ChDC B594) ALD69358.1    
 RN83_08260   Cutibacterium acnes KCOM 1861 (= ChDC B594) ALD70051.1    
 sialidase (PPA1560)   Cutibacterium acnes KPA171202 AAT83304.1 Q6A7G1  
 PPA0685   Cutibacterium acnes KPA171202 AAT82441.1 Q6A9X5  
 PPA0684   Cutibacterium acnes KPA171202 AAT82440.1 Q6A9X6  
 ALW29_03475   Cutibacterium acnes PA_12_1_L1 ALT41780.1    
 ALW29_07860   Cutibacterium acnes PA_12_1_L1 ALT42513.1    
 ALW29_03480   Cutibacterium acnes PA_12_1_L1 ALT41781.1    
 ALW27_03490   Cutibacterium acnes PA_12_1_R1 ALT39544.1    
 ALW27_03485   Cutibacterium acnes PA_12_1_R1 ALT39543.1    
 ALW27_07840   Cutibacterium acnes PA_12_1_R1 ALT40274.1    
 ALW33_03630   Cutibacterium acnes PA_15_1_R1 ALT44065.1    
 ALW33_03625   Cutibacterium acnes PA_15_1_R1 ALT44064.1    
 ALW33_07890   Cutibacterium acnes PA_15_1_R1 ALT44783.1    
 ALW23_03630   Cutibacterium acnes PA_15_2_L1 ALT37265.1    
 ALW23_03635   Cutibacterium acnes PA_15_2_L1 ALT37266.1    
 ALW23_07985   Cutibacterium acnes PA_15_2_L1 ALT38000.1    
 ALW21_03495   Cutibacterium acnes PA_21_1_L1 ALT34956.1    
 ALW21_07890   Cutibacterium acnes PA_21_1_L1 ALT35678.1    
 ALW21_03500   Cutibacterium acnes PA_21_1_L1 ALT34957.1    
 ALW22_03520   Cutibacterium acnes PA_30_2_L1 ALT32700.1    
 ALW22_07885   Cutibacterium acnes PA_30_2_L1 ALT33417.1    
 ALW22_03515   Cutibacterium acnes PA_30_2_L1 ALT32699.1    
 TIIST44_00800   Cutibacterium acnes subsp. defendens ATCC 11828 AER04689.1    
 TIIST44_11035   Cutibacterium acnes subsp. defendens ATCC 11828 AER06660.1    
 TIIST44_11040   Cutibacterium acnes subsp. defendens ATCC 11828 AER06661.1    
 TIA2EST22_07825   Cutibacterium acnes TypeIA2 P.acn17 AEW81871.1    
 TIA2EST22_03465   Cutibacterium acnes TypeIA2 P.acn17 AEW81015.1    
 TIA2EST22_03460 (fragment)   Cutibacterium acnes TypeIA2 P.acn17 AEW81014.1    
 TIA2EST36_07805   Cutibacterium acnes TypeIA2 P.acn31 AEW84137.1    
 TIA2EST36_03430   Cutibacterium acnes TypeIA2 P.acn31 AEW83281.1    
 TIA2EST36_03425 (fragment)   Cutibacterium acnes TypeIA2 P.acn31 AEW83280.1    
 TIA2EST2_07735   Cutibacterium acnes TypeIA2 P.acn33 AEW79628.1    
 TIA2EST2_03385   Cutibacterium acnes TypeIA2 P.acn33 AEW78772.1    
 CA2015_2379   Cyclobacterium amurskyense KCTC 12363 AKP51795.1    
 neuraminidase   Cyclobacterium amurskyense KCTC 12363 AKP51429.1    
 CA2015_2865   Cyclobacterium amurskyense KCTC 12363 AKP52272.1    
 CA2015_2378   Cyclobacterium amurskyense KCTC 12363 AKP51794.1    
 CA2015_3736   Cyclobacterium amurskyense KCTC 12363 AKP53111.1    
 CA2015_4257   Cyclobacterium amurskyense KCTC 12363 AKP53604.1    
 CA2015_0731   Cyclobacterium amurskyense KCTC 12363 AKP50194.1    
 CA2015_2005   Cyclobacterium amurskyense KCTC 12363 AKP51431.1    
 CA2015_2363   Cyclobacterium amurskyense KCTC 12363 AKP51779.1    
 CA2015_0291   Cyclobacterium amurskyense KCTC 12363 AKP49771.1    
 CA2015_0288   Cyclobacterium amurskyense KCTC 12363 AKP49768.1    
 CA2015_2376   Cyclobacterium amurskyense KCTC 12363 AKP51792.1    
 CA2015_2380   Cyclobacterium amurskyense KCTC 12363 AKP51796.1    
 CA2015_3667   Cyclobacterium amurskyense KCTC 12363 AKP53044.1    
 Cycma_0384   Cyclobacterium marinum DSM 745 AEL24163.1    
 Cycma_0387   Cyclobacterium marinum DSM 745 AEL24166.1    
 Cycma_2061   Cyclobacterium marinum DSM 745 AEL25808.1    
 Cycma_2063   Cyclobacterium marinum DSM 745 AEL25810.1    
 Cycma_2430   Cyclobacterium marinum DSM 745 AEL26172.1    
 Cycma_2432   Cyclobacterium marinum DSM 745 AEL26174.1    
 Cycma_2433   Cyclobacterium marinum DSM 745 AEL26175.1    
 Cycma_2435   Cyclobacterium marinum DSM 745 AEL26177.1    
 Cycma_3733   Cyclobacterium marinum DSM 745 AEL27445.1    
 Cycma_3805   Cyclobacterium marinum DSM 745 AEL27516.1    
 Cycma_4329   Cyclobacterium marinum DSM 745 AEL28031.1    
 SAMN06298216_1299   Cytophagales bacterium TFI 002 SOE20818.1    
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