Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (5863); Uniprot accession (681); PDB accession (152); 3D entries (21); cryst (0)
All (5623) Archaea (1) Bacteria (5166) Eukaryota (415) Viruses (35) unclassified (6) Structure (21) Characterized (97)
| 1 | ... | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ... | 53 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 LH89_13075   Cedecea neteri ND14b AIR70090.1    
 LH89_16250   Cedecea neteri ND14b AIR70683.1    
 sialidase   Cellulosimicrobium cellulans 21 ANR02616.1    
 FOG94_03025   Cellulosimicrobium cellulans NEB113 QDP74262.1    
 CBR64_08430   Cellulosimicrobium cellulans PSBB019 ARU51502.1    
 B8281_03265   Cellulosimicrobium sp. TH-20 ARK03899.1    
 Z042_19405   Chania multitudinisentens RB-25 AHG21530.1    
 COR50_02120   Chitinophaga caeni ATL46053.1    
 Cpin_1807   Chitinophaga pinensis DSM 2588 ACU59303.1 C7PA66  
 neuraminidase   Chitinophaga pinensis DSM 2588 ACU64580.1 C7PTY5  
 DLD77_03580   Chitinophaga sp. T22 AWO00841.1    
 DLD77_05225   Chitinophaga sp. T22 AWO01132.1    
 DLD77_03630   Chitinophaga sp. T22 AWO00850.1    
 FW415_22800   Chitinophaga sp. XS-30 QEH43526.1    
 FW415_13185   Chitinophaga sp. XS-30 QEH41786.1    
 FW415_22795   Chitinophaga sp. XS-30 QEH43525.1    
 FW415_22815   Chitinophaga sp. XS-30 QEH43529.1    
 FW415_14730   Chitinophaga sp. XS-30 QEH42059.1    
 FW415_13205   Chitinophaga sp. XS-30 QEH44039.1    
 FW415_14035   Chitinophaga sp. XS-30 QEH44057.1    
 CA1H_7101 (fragment)   Chlamydia abortus 1H CED81651.1    
 DZK34_03400   Chlamydia abortus 84/2334 QEM73987.1    
 AB7_7101 (fragment)   Chlamydia abortus AB7 CED80691.1
CEF17097.1
   
 CHAB577_0694 (fragment)   Chlamydia abortus GIMC 2006:CabB577 AUS60115.1    
 CAB1_0654   Chlamydia abortus LLG EGK69379.1    
 CPS0A_0729   Chlamydia psittaci 01DC11 AEG86676.1    
 BN356_6571   Chlamydia psittaci 01DC12 CCO02158.1    
 CPS0B_0720   Chlamydia psittaci 02DC15 AEG87654.1    
 CPS0D_0725   Chlamydia psittaci 08DC60 AEG88627.1    
 CPSIT_0711   Chlamydia psittaci 6BC ADZ18791.1
AEB55681.1
   
 B595_0770   Chlamydia psittaci 84/55 AFS19729.1    
 CPS0C_0726   Chlamydia psittaci C19/98 AEG85701.1    
 B711_0772   Chlamydia psittaci CP3 AFS27165.1    
 D3X08_03375   Chlamydia psittaci Ful127 AZU10779.1    
 CHPS25_0682   Chlamydia psittaci GIMC 2003:Cps25SM ATQ71701.1    
 CHPS23_0684   Chlamydia psittaci GIMC 2004:CpsAP23 ATQ72728.1    
 CHPS1_0685   Chlamydia psittaci GIMC 2005:CpsCP1 ATQ79972.1    
 B598_0713   Chlamydia psittaci GR9 AFS20791.1    
 CX655_03410   Chlamydia psittaci Horse_pl AUH45922.1    
 B602_0720   Chlamydia psittaci M56 AFS24928.1    
 AO9_03425   Chlamydia psittaci Mat116 AGE75243.1    
 B599_0718   Chlamydia psittaci MN AFS21540.1    
 B712_0716   Chlamydia psittaci NJ1 AFS28225.1    
 Cpsi_6531   Chlamydia psittaci RD1 CBY17171.1 E5AIE1  
 FI836_00910   Chlamydia psittaci Rostinovo-70 QDE36887.1    
 B600_0767   Chlamydia psittaci VS225 AFS22917.1    
 B603_0723   Chlamydia psittaci WC AFS25884.1    
 B601_0714   Chlamydia psittaci WS/RT/E30 AFS24251.1    
 D4L85_13685   Chryseolinea sp. KIS68-18 AYB31556.1    
 D4L85_00675   Chryseolinea sp. KIS68-18 AYB29184.1    
 E2R62_04090   Citrobacter rodentium DBS100 QBY28106.1    
 ROD_15131   Citrobacter rodentium ICC168 CBG88277.1 D2TIF0  
 CLS_13500   [Clostridium] cf. saccharolyticum K10 CBK76990.1 D6DH16  
 BTM20_05845   Clostridium chauvoei 12S0467 ATD54786.1    
 BTM21_07215   Clostridium chauvoei DSM 7528 ATD57534.1    
 NanA (fragment)   Clostridium chauvoei JF3703 CAR82360.1 E1UGY3  
 sialidase (NanA) (fragment) 3.2.1.18 Clostridium chauvoei JF4135 CAR82361.1 E1UGY4  
 CCH01_10370   Clostridium chauvoei JF4335 SLK16343.1    
 C6H62_05085   Clostridium chauvoei SBP 07/09 QBJ75069.1    
 sialidase 1 'small' 3.2.1.18 Clostridium perfringens A99 CAA68780.1 P10481  
 exo-α-sialidase 'large' (NanH) 3.2.1.18 Clostridium perfringens A99 CAA60796.1 Q59310  
 sialidase 2 (NanH) 3.2.1.18 Clostridium perfringens ATCC 10543 CAA50436.1 Q59311  
 sialidase (CpNanI;CPF_0721) 3.2.1.18 Clostridium perfringens ATCC 13124 ABG83208.1 Q0TT67 4L2E[A]
5TSP[A,B]
 CPF_0985   Clostridium perfringens ATCC 13124 ABG84018.1 Q0TSF8  
 CPF_0532   Clostridium perfringens ATCC 13124 ABG84247.1 Q0TTQ4  
 NanI, partial   Clostridium perfringens CN3718 APZ74275.1    
 BXT91_02895   Clostridium perfringens CP15 AQW22891.1    
 BXT91_04080   Clostridium perfringens CP15 AQW23115.1    
 BXT91_05085   Clostridium perfringens CP15 AQW23307.1    
 BXT94_04320   Clostridium perfringens Del1 AQW26025.1    
 BXT94_09915   Clostridium perfringens Del1 AQW27075.1    
 BXT94_05545   Clostridium perfringens Del1 AQW26258.1    
 BG908_09070   Clostridium perfringens EHE-NE18 ASY51800.1
AWS26319.1
   
 BG908_04100   Clostridium perfringens EHE-NE18 ASY50870.1
AWS25363.1
   
 BG908_02920   Clostridium perfringens EHE-NE18 ASY50649.1
AWS25149.1
   
 BG908_05115   Clostridium perfringens EHE-NE18 ASY51063.1
AWS25561.1
   
 FORC3_0555   Clostridium perfringens FORC_003 ALG47932.1    
 FORC3_1686   Clostridium perfringens FORC_003 ALG49063.1    
 FORC3_0922   Clostridium perfringens FORC_003 ALG48299.1    
 FORC3_0721   Clostridium perfringens FORC_003 ALG48098.1    
 FORC25_0523   Clostridium perfringens FORC_025 AOY52943.1    
 FORC25_0716   Clostridium perfringens FORC_025 AOY53136.1    
 FORC25_0968   Clostridium perfringens FORC_025 AOY53385.1    
 JFP55_03020   Clostridium perfringens JP55 AMN31934.1    
 JFP55_05480   Clostridium perfringens JP55 AMN32383.1    
 JFP55_04220   Clostridium perfringens JP55 AMN32150.1    
 JFP838_05320   Clostridium perfringens JP838 AMN35195.1    
 JFP838_04060   Clostridium perfringens JP838 AMN34958.1    
 JFP838_02940   Clostridium perfringens JP838 AMN34751.1    
 C8114_03905   Clostridium perfringens JXJA17 AXH51780.1    
 C8114_03000   Clostridium perfringens JXJA17 AXH51610.1    
 C8114_05170   Clostridium perfringens JXJA17 AXH52021.1    
 CMR01_06170   Clostridium perfringens LLY_N11 ATD48363.1    
 CMR01_11265   Clostridium perfringens LLY_N11 ATD49336.1    
 CMR01_12460   Clostridium perfringens LLY_N11 ATD49562.1    
 CMR01_10260   Clostridium perfringens LLY_N11 ATD49144.1    
 NCTC13170_01802   Clostridium perfringens NCTC13170 SQG39657.1    
 NCTC13170_00586 (NanJ)   Clostridium perfringens NCTC13170 SQG37829.1    
 NCTC13170_01032 (NanH)   Clostridium perfringens NCTC13170 SQG38313.1    
 NCTC13170_00788 (NanI)   Clostridium perfringens NCTC13170 SQG38020.1    
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