Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (5231); Uniprot accession (686); PDB accession (146); 3D entries (19); cryst (0)
All (4988) Archaea (1) Bacteria (4552) Eukaryota (395) Viruses (34) unclassified (6) Structure (19) Characterized (96)
| 1 | ... | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | ... | 47 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 neuraminidase   Cytophagales bacterium TFI 002 SOE23663.1    
 Daro_0557   Dechloromonas aromatica RCB AAZ45314.1 Q47IL7  
 HYN24_02415   Dechloromonas sp. HYN0024 AXS78988.1    
 DTL3_1050   Defluviitoga tunisiensis CEP78354.1    
 E5F05_01590   Deinococcus metallilatus MA1002 QBY06672.1    
 COP05_01045   Dermabacter jinjuensis 32T ATH95834.1    
 COP05_01020   Dermabacter jinjuensis 32T ATH95829.1    
 DAD186_19940   Dermabacter vaginalis AD1-86 ANP28544.1    
 DAD186_19890   Dermabacter vaginalis AD1-86 ANP28539.1    
 XM25_15840   Devosia sp. H5989 AKR57229.1    
 XM25_05200   Devosia sp. H5989 AKR55212.1    
 DAQ1742_03780   Dickeya aquatica 174/2 SLM64574.1    
 Dd1591_0644   Dickeya chrysanthemi Ech1591 ACT05526.1 C6CK10  
 Dda3937_02530   Dickeya dadantii 3937 ADM96302.1 E0SEP9  
 Dda3937_02632   Dickeya dadantii 3937 ADN00006.1 E0SFF3  
 DZA65_03685   Dickeya dianthicola ME23 AYC20537.1    
 DDI_3514   Dickeya dianthicola RNS04.9 ATO34682.1    
 CVE23_21810   Dickeya fangzhongdai DSM 101947 ATZ96377.1    
 CVE23_18675   Dickeya fangzhongdai DSM 101947 ATZ95815.1    
 B6N31_18335   Dickeya fangzhongdai PA1 AYH49464.1    
 B6N31_21445   Dickeya fangzhongdai PA1 AYH50029.1    
 Dd703_0687   Dickeya paradisiaca Ech703 ACS84498.1 C6CA23  
 Dd703_3918   Dickeya paradisiaca Ech703 ACS87671.1 C6C662  
 BJD21_12655 (fragment)   Dickeya solani D s0432-1 AUH09234.1    
 BJD21_15715   Dickeya solani D s0432-1 AUH09788.1    
 DSOL99_04177 (fragment)   Dickeya solani IFB 0099 AYQ54065.1    
 DSOL99_03548   Dickeya solani IFB 0099 AYQ53468.1    
 CTB91_03550   Dickeya solani IFB0223 AYQ49304.1    
 CTB91_04179 (fragment)   Dickeya solani IFB0223 AYQ49901.1    
 A4U42_05320   Dickeya solani IPO 2222 ANE74796.1    
 A4U42_08380 (fragment)   Dickeya solani IPO 2222 ANE75352.1    
 BJJ98_12620 (fragment)   Dickeya solani PPO 9019 AUH13206.1    
 BJJ98_15685   Dickeya solani PPO 9019 AUH13748.1    
 D083_2411 (fragment)   Dickeya solani RNS 08.23.3.1.A AUC42760.1    
 D083_1754   Dickeya solani RNS 08.23.3.1.A AUC42103.1    
 W909_16765   Dickeya zeae EC1 AJC67631.1    
 W909_19770   Dickeya zeae EC1 AJC68196.1    
 Dd586_3498   Dickeya zeae Ech586 ACZ78328.1 D2BWH5  
 Dd586_4080   Dickeya zeae Ech586 ACZ78906.1 D2BZN4  
 C1O30_17610   Dickeya zeae MS2 AUQ26749.1    
 C1O30_20680   Dickeya zeae MS2 AUQ27312.1    
 FH5T_01145   Draconibacterium orientale FH5 AHW58654.1    
 FH5T_13900   Draconibacterium orientale FH5 AHW60355.1    
 FDZ78_06670 (fragment)   Duncaniella sp. B8 QCP72278.1    
 E7745_02940 (fragment)   Duncaniella sp. C9 QCD38586.1    
 Dfer_2148   Dyadobacter fermentans DSM 18053 ACT93371.1 C6VYL6  
 Dfer_2863   Dyadobacter fermentans DSM 18053 ACT94078.1 C6W4H7  
 Dfer_3020   Dyadobacter fermentans DSM 18053 ACT94235.1 C6W5L7  
 FKX85_16345   Echinicola sp. LN3S3 QDH80524.1    
 FKX85_07945   Echinicola sp. LN3S3 QDH78971.1    
 FKX85_02160   Echinicola sp. LN3S3 QDH81455.1    
 DN752_14255   Echinicola strongylocentroti MEBiC08714 AWW31195.1    
 DN752_04810   Echinicola strongylocentroti MEBiC08714 AWW29506.1    
 neuraminidase   Echinicola vietnamensis DSM 17526 AGA76790.1    
 Echvi_1665   Echinicola vietnamensis DSM 17526 AGA77930.1    
 Echvi_4341   Echinicola vietnamensis DSM 17526 AGA80527.1    
 ETEE_3198 (fragment)   Edwardsiella anguillarum ET080813 AIJ09625.1    
 A9798_10455   Edwardsiella hoshinae ATCC 35051 AOV98594.1    
 ETAC_05915   Edwardsiella piscicida C07-087 AGH73308.1    
 BXA22_01835   Edwardsiella piscicida ETW41 ARD17174.1    
 EVK84_01165   Edwardsiella piscicida MS-18-199 QBB14338.1    
 A9797_06095   Edwardsiella piscicida S11-285 AOP42629.1    
 sialidase NanA   Edwardsiella tarda E01-21 BAV69399.1    
 NanA sialidase   Edwardsiella tarda E22 BAX03532.1    
 NanA sialidase   Edwardsiella tarda E381 BAV59436.1    
 ETAE_1245   Edwardsiella tarda EIB202 ACY84088.1 D0ZFQ6  
 ORF   Edwardsiella tarda ET-1 BAU80413.1    
 ETAF_1161   Edwardsiella tarda FL6-60 ADM41276.1 E0T4S6  
 sialidase (NanA)   Edwardsiella tarda FPC 498 BAP91033.1    
 NanA sialidase   Edwardsiella tarda NUF806 BAV59437.1    
 NanA sialidase   Edwardsiella tarda SU138 BAX36558.1    
 NanA sialidase   Edwardsiella tarda SU226 BAX03533.1    
 sialidase (NanA) 3.2.1.18 Edwardsiella tarda TX01 AFP73415.1    
 BBD33_05820   Elizabethkingia meningoseptica G4076 AQX04795.1    
 BBD35_07650   Elizabethkingia meningoseptica G4120 AQX12256.1    
 B5G46_05815   Elizabethkingia meningoseptica KC1913 AQX46837.1    
 NCTC10016_01251 (Neda_2)   Elizabethkingia meningoseptica NCTC10016 SQG06338.1    
 FGE20_10510   Elizabethkingia sp. JS20170427COW QCX54140.1    
 Emtol_2335   Emticicia oligotrophica DSM 17448 AFK03472.1    
 neuraminidase   Emticicia oligotrophica DSM 17448 AFK05157.1    
 neuraminidase   Emticicia oligotrophica DSM 17448 AFK05192.1    
 EZMO1_1737 (fragment)   Endozoicomonas montiporae CL-33 AMO55886.1    
 EZMO1_1736 (fragment)   Endozoicomonas montiporae CL-33 AMO55885.1    
 FA04_32600   Ensifer adhaerens Casida A ANK77378.1    
 OV14_b0333   Ensifer adhaerens OV14 AHK46900.1    
 SJ05684_c15290   Ensifer sojae CCBAU 05684 ASY62971.1    
 AB190_04710   Enterobacter asburiae CAV1043 AKK99904.1
AZL61628.1
   
 A0R60_0918   Enterobacter asburiae ENIPBJ-CG1 AMX05225.1    
 Entas_2142   Enterobacter asburiae LF7a AEN64876.1    
 E7739_15145   Enterobacter cloacae Effluent_2 QCC97247.1    
 E7735_15450   Enterobacter cloacae Effluent_3 QCC92246.1    
 E7729_09470   Enterobacter cloacae Effluent_4 QCD10819.1    
 EC036_21440   Enterobacter cloacae GGT036 AIV29791.1    
 BFJ73_10280   Enterobacter cloacae isolate SBP-8 AOE95581.1    
 BJM06_02266   Enterobacter cloacae M12X01451 ASQ18057.1    
 FGL54_02045   Enterobacter cloacae NH77 QCZ37336.1    
 B2J95_12170   Enterobacter cloacae Res2010EC27 AVL18757.1    
 ECL_02001   Enterobacter cloacae subsp. cloacae ATCC 13047 ADF61553.1 D5C8V6  
 A3UG_11160   Enterobacter cloacae subsp. dissolvens SDM AFM59966.1    
 AKI40_3003   Enterobacter sp. FY-07 AMO49388.1    
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