Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); 2-keto-3-deoxynononic acid hydrolase (EC 3.2.1.-); anhydrosialidase (EC 4.2.2.15); 3-deoxy-D-manno-octulosonic-acid hydrolase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (3514); Uniprot accession (686); PDB accession (144); 3D entries (19); cryst (0)
All (3255) Archaea (1) Bacteria (2851) Eukaryota (371) Viruses (32) Structure (19) Characterized (96)
| 1 | ... | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ... | 30 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 JFP55_03020   Clostridium perfringens JP55 AMN31934.1    
 JFP55_05480   Clostridium perfringens JP55 AMN32383.1    
 JFP55_04220   Clostridium perfringens JP55 AMN32150.1    
 JFP838_05320   Clostridium perfringens JP838 AMN35195.1    
 JFP838_04060   Clostridium perfringens JP838 AMN34958.1    
 JFP838_02940   Clostridium perfringens JP838 AMN34751.1    
 CMR01_06170   Clostridium perfringens LLY_N11 ATD48363.1    
 CMR01_11265   Clostridium perfringens LLY_N11 ATD49336.1    
 CMR01_12460   Clostridium perfringens LLY_N11 ATD49562.1    
 CMR01_10260   Clostridium perfringens LLY_N11 ATD49144.1    
 CPR_0877   Clostridium perfringens SM101 ABG86307.1 Q0SUK5  
 exo-α-sialidase (NanJ;CPE0553) 3.2.1.18 Clostridium perfringens str. 13 BAB80259.1
NP_561469.1
Q8XMY5  
 exo-α-sialidase (NanI;CPSA;CPE0725) 3.2.1.18 Clostridium perfringens str. 13 BAB80431.1
NP_561641.1
Q8XMG4 2BF6[A]
2VK5[A]
2VK6[A]
2VK7[A,B]
 neuraminidase   Clostridium saccharoperbutylacetonicum N1-4(HMT) AGF57738.1    
 sialidase 3.2.1.18 Clostridium septicum NC0054714 CAA44916.1 P29767  
 neuraminidase   [Clostridium] sphenoides JCM 1415 ATCC 19403 SET85419.1    
 ZP_02867864.1   Clostridium spiroforme DSM 1552 ZP_02867864.1 B1C387  
 sialidase (NanH;SiaH) 3.2.1.18 Clostridium tertium CAA69951.1 P77848  
 neuraminidase   Cohaesibacter sp. ES.047 SNY92957.1    
 O987_20575   Comamonas testosteroni TK102 AIJ48208.1    
 CC1_03920   Coprococcus catus GD/7 CBK79325.1 D4J4Q4  
 JI75_01895   Coriobacteriaceae bacterium 68-1-3 AJC11622.1    
 CAQU_07700   Corynebacterium aquilae DSM 44791 S-613 APT84974.1    
 CAQU_01300   Corynebacterium aquilae DSM 44791 S-613 APT83930.1    
 H924_11155   Corynebacterium callunae DSM 20147 AGG67659.1    
 CCASEI_03525   Corynebacterium casei LMG S-19264 AHI19285.1    
 CDES_12030   Corynebacterium deserti GIMN1.010 ALC06756.1    
 CD241_0285   Corynebacterium diphtheriae 241 AEX43353.1    
 CD241_0480 (NanH)   Corynebacterium diphtheriae 241 AEX43547.1    
 CD31A_0333   Corynebacterium diphtheriae 31A AEX41018.1    
 CD31A_0540 (NanH)   Corynebacterium diphtheriae 31A AEX41224.1    
 BS112_10690   Corynebacterium diphtheriae B-D-16-78 APM36886.1    
 BS112_09660   Corynebacterium diphtheriae B-D-16-78 APM36707.1    
 CDBH8_0495 (NanH)   Corynebacterium diphtheriae BH8 AEX48020.1    
 CDBH8_0280   Corynebacterium diphtheriae BH8 AEX47805.1    
 CDC7B_0498 (NanH)   Corynebacterium diphtheriae C7 (beta) AEX66697.1    
 CDC7B_0282   Corynebacterium diphtheriae C7 (beta) AEX66482.1    
 CDCE8392_0286   Corynebacterium diphtheriae CDCE 8392 AEX71288.1    
 CDCE8392_0488 (NanH)   Corynebacterium diphtheriae CDCE 8392 AEX71488.1    
 A6J36_10310   Corynebacterium diphtheriae FDAARGOS_197 ARB88654.1    
 A6J36_11360   Corynebacterium diphtheriae FDAARGOS_197 ARB89035.1    
 CDHC01_0286   Corynebacterium diphtheriae HC01 AEX73539.1    
 CDHC01_0481 (NanH)   Corynebacterium diphtheriae HC01 AEX73734.1    
 CDHC02_0291   Corynebacterium diphtheriae HC02 AEX75787.1    
 CDHC02_0488 (NanH)   Corynebacterium diphtheriae HC02 AEX75984.1    
 CDHC03_0263   Corynebacterium diphtheriae HC03 AEX77994.1    
 CDHC03_0467 (NanH)   Corynebacterium diphtheriae HC03 AEX78198.1    
 CDHC04_0246   Corynebacterium diphtheriae HC04 AEX80239.1    
 CDHC04_0446 (NanH)   Corynebacterium diphtheriae HC04 AEX80439.1    
 CDB402_0252   Corynebacterium diphtheriae INCA 402 AEX45563.1    
 CDB402_0452 (NanH)   Corynebacterium diphtheriae INCA 402 AEX45763.1    
 trans-sialidase (NanH;NanA) 2.4.1.- Corynebacterium diphtheriae KCTC 3075 ACS34893.1 C6JSW6  
 sialidase (NanI;NanB)   Corynebacterium diphtheriae KCTC 3075 ACS34894.1 C6JSW7  
 DIP0543   Corynebacterium diphtheriae NCTC 13129 CAE49054.1
NP_938919.1
   
 DIP0330   Corynebacterium diphtheriae NCTC 13129 CAE48837.1
NP_938718.1
   
 ERS451417_00260 (NanI)   Corynebacterium diphtheriae NCTC11397 CKG64847.1    
 ERS451417_00477 (NanH)   Corynebacterium diphtheriae NCTC11397 CKG71642.1    
 CDPW8_0344   Corynebacterium diphtheriae PW8 AEX69006.1    
 CDPW8_0542 (NanH)   Corynebacterium diphtheriae PW8 AEX69204.1    
 CDVA01_0230   Corynebacterium diphtheriae VA01 AEX82499.1    
 CDVA01_0429 (NanH)   Corynebacterium diphtheriae VA01 AEX82698.1    
 CEPID_03560   Corynebacterium epidermidicanis DSM 45586 AKK02590.1    
 RXN02478   Corynebacterium glutamicum CAC26191.1 Q8NMC8  
 FRXA02513 / RXN02513 (fragment)   Corynebacterium glutamicum CAC26187.1
AAW20926.1
CAC26186.1
CAL31683.1
CAL31684.1
   
 RXA00984 (fragment)   Corynebacterium glutamicum CAC26185.1
CAL31682.1
   
 CGBL_0116740 (NanH) (fragment)   Corynebacterium glutamicum AJ1511 BAV23396.1    
 CGBL_0116750 (NanH) (fragment)   Corynebacterium glutamicum AJ1511 BAV23397.1    
 CGBL_0125870 (NanH)   Corynebacterium glutamicum AJ1511 BAV24278.1    
 cg1756 (NanH)   Corynebacterium glutamicum ATCC 13032 CAF21565.1
BAB98949.1
CCH24715.1
NP_600771.1
Q6M535  
 cg2935 (NanP)   Corynebacterium glutamicum ATCC 13032 BAC00044.1
ABC13268.1
CAF21311.1
CAL31688.1
CCH25780.1
NP_601849.1
Q8NMC8  
 BBD29_12965   Corynebacterium glutamicum ATCC 13869 ANU34577.1    
 cgc1_2935 (NanP)   Corynebacterium glutamicum C1 ASW14966.1    
 cgc1_1756 (NanH)   Corynebacterium glutamicum C1 ASW14166.1    
 AC079_13165   Corynebacterium glutamicum CP18 ALP51049.1    
 cgp_2935 (NanP)   Corynebacterium glutamicum MB001 AGT06367.1    
 cgp_1756 (NanH)   Corynebacterium glutamicum MB001 AGT05516.1    
 N24_2734 (NanP)   Corynebacterium glutamicum N24 BAU96996.1    
 cgR_1608   Corynebacterium glutamicum R BAF54600.1    
 cgR_2554   Corynebacterium glutamicum R BAF55566.1    
 C624_13025   Corynebacterium glutamicum SCgG1 AGN20172.1    
 C624_08555   Corynebacterium glutamicum SCgG1 AGN19286.1    
 C629_13030   Corynebacterium glutamicum SCgG2 AGN23196.1    
 C629_08565   Corynebacterium glutamicum SCgG2 AGN22311.1    
 B7P23_15235   Corynebacterium glutamicum TQ2223 ARV66138.1    
 B7P23_05095   Corynebacterium glutamicum TQ2223 ARV64311.1    
 APT58_13045   Corynebacterium glutamicum USDA-ARS-USMARC-56828 AMA01077.1    
 BSP99_13380   Corynebacterium glutamicum XV APT08329.1    
 A3654_08265   Corynebacterium glutamicum YI ANE08356.1    
 C627_08425 (fragment)   Corynebacterium glutamicum ZL-6 ANR65645.1    
 C627_13015   Corynebacterium glutamicum ZL-6 ANR66531.1    
 C627_08430 (fragment)   Corynebacterium glutamicum ZL-6 ANR65646.1    
 ckrop_1872 (NanI)   Corynebacterium kroppenstedtii DSM 44385 ACR18588.1 C4LL83  
 CMUST_11800   Corynebacterium mustelae DSM 45274 AKK06671.1    
 CMUST_04910   Corynebacterium mustelae DSM 45274 AKK05320.1    
 CPHO_04675   Corynebacterium phocae M408/89/1 APT92300.1    
 Cp1002_0387   Corynebacterium pseudotuberculosis 1002 ADL20287.1 D9Q6J2  
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis 1002B ALM77000.1    
 Cp12C_0413 (NanH)   Corynebacterium pseudotuberculosis 12C AKJ55057.1    
 Cp226_0402 (NanH)   Corynebacterium pseudotuberculosis 226 AKC73144.1    
 Cp258_0396 (NanH)   Corynebacterium pseudotuberculosis 258 AJF93848.1    
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