Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (5022); Uniprot accession (686); PDB accession (146); 3D entries (19); cryst (0)
All (4783) Archaea (1) Bacteria (4345) Eukaryota (389) Viruses (34) unclassified (14) Structure (19) Characterized (96)
| 1 | ... | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | ... | 45 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CpMEX31_0432 (NanH)   Corynebacterium pseudotuberculosis MEX31 APQ55593.1    
 CpMEX9_0403 (NanH)   Corynebacterium pseudotuberculosis MEX9 ANH25216.1    
 CpMIC6_0417 (NanH)   Corynebacterium pseudotuberculosis MIC6 AQU92087.1    
 CpN1_0402 (NanH)   Corynebacterium pseudotuberculosis N1 ALP33124.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis OVI03 AUZ42318.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis OVI2C AUY06410.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis OVIAF1 AZN21382.1    
 CpP54B96_0391 (NanH)   Corynebacterium pseudotuberculosis P54B96 AFF21544.1    
 CpPA01_0371 (NanH)   Corynebacterium pseudotuberculosis PA01 ALR33038.1    
 CpPA02_0369 (NanH)   Corynebacterium pseudotuberculosis PA02 ANK55784.1    
 CpPA04_0393   Corynebacterium pseudotuberculosis PA04 AQL50505.1    
 CpPA05_02990   Corynebacterium pseudotuberculosis PA05 APX35569.1    
 CpPA06_02430   Corynebacterium pseudotuberculosis PA06 APX37410.1    
 CpPA07_0394 (NanH)   Corynebacterium pseudotuberculosis PA07 ATQ64714.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis PA08; A19 ATQ80695.1    
 CpPAT10_0391 (NanH)   Corynebacterium pseudotuberculosis PAT10 AEK91723.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis phoP AQU90003.1    
 AK970_01940   Corynebacterium pseudotuberculosis PO222/4-1 ALU18978.1    
 AN902_01950   Corynebacterium pseudotuberculosis PO269-5 ALF56960.1    
 CpSigmaE_0400 (NanH)   Corynebacterium pseudotuberculosis SigmaE ARB41976.1    
 CpT1_0395 (NanH)   Corynebacterium pseudotuberculosis T1 ANQ78695.1    
 CpVD57_0395 (NanH)   Corynebacterium pseudotuberculosis VD57 AJC13124.1    
 C3B44_08125 (fragment)   Corynebacterium sp. 2183 AWB82324.1    
 CTEST_12930 (NanI)   Corynebacterium testudinoris DSM 44614 AKK09989.1    
 CULC0102_0481 (NanH)   Corynebacterium ulcerans 0102 BAM26683.1    
 Cul05146_0470 (NanH)   Corynebacterium ulcerans 05146 AIU91055.1    
 Cul131001_0462 (NanH)   Corynebacterium ulcerans 131001 ALD94188.1    
 CUL131002_0438 (NanH)   Corynebacterium ulcerans 131002 AKA95986.1    
 Cul210931_0440 (NanH)   Corynebacterium ulcerans 210931 AIU29801.1    
 Cul210932_0455 (NanH)   Corynebacterium ulcerans 210932 AIT88419.1    
 CULC809_00434 (NanH)   Corynebacterium ulcerans 809 AEG80974.1    
 CULC22_00437 (NanH)   Corynebacterium ulcerans BR-AD22 AEG83155.1    
 CulFRC11_0435 (NanH)   Corynebacterium ulcerans FRC11 AIU32028.1    
 CulFRC58_0499 (NanH)   Corynebacterium ulcerans FRC58 AKN76353.1    
 NCTC7908_01438 (NanH)   Corynebacterium ulcerans NCTC7908 SQG51860.1    
 SAMEA4504038_01773 (NanH)   Corynebacterium ulcerans NCTC7910 SNV12433.1    
 NCTC8639_01079 (NanH)   Corynebacterium ulcerans NCTC8639 SQH02603.1    
 CBE74_02420   Corynebacterium ulcerans PO100/5 ARU45544.1    
 CUTER_01555   Corynebacterium uterequi DSM 45634 AKK10327.1    
 CUTER_03660   Corynebacterium uterequi DSM 45634 AKK10740.1    
 CUTER_01485   Corynebacterium uterequi DSM 45634 AKK10313.1    
 BKK80_26820   Cupriavidus sp. USMAA1020 AOZ09393.1    
 BKK79_32725   Cupriavidus sp. USMAA2-4 AOY96358.1    
 BKK81_29535   Cupriavidus sp. USMAHM13 AOZ03243.1    
 Csp_A02540   Curvibacter putative symbiont of Hydra magnipapillata CBA27491.1 C9Y803  
 AEP_03366   Curvibacter sp. AEP1-3 ARV20288.1    
 PAZ_c07300 (NanA)   Cutibacterium acnes 266 AEE71914.1    
 PAZ_c07290   Cutibacterium acnes 266 AEE71913.1    
 PAZ_c16480   Cutibacterium acnes 266 AEE72802.1    
 TIB1ST10_03525   Cutibacterium acnes 6609 AEH29013.1    
 TIB1ST10_08010   Cutibacterium acnes 6609 AEH29886.1    
 TIB1ST10_03520 (fragment)   Cutibacterium acnes 6609 AEH29012.1    
 VO62_03330   Cutibacterium acnes A1-14 ALU23131.1    
 VO62_07505   Cutibacterium acnes A1-14 ALU23799.1    
 VO62_03325   Cutibacterium acnes A1-14 ALU23130.1    
 CPA42_03740   Cutibacterium acnes ATCC 6919 AVT26227.1    
 CPA42_03735   Cutibacterium acnes ATCC 6919 AVT26226.1    
 CPA42_08430   Cutibacterium acnes ATCC 6919 AVT27023.1    
 PAC1_03555   Cutibacterium acnes C1 AFU40475.1    
 PAC1_03550 (fragment)   Cutibacterium acnes C1 AFU40474.1    
 EGY06_11845   Cutibacterium acnes FDAARGOS_503 AYZ26396.1    
 EGY06_03995   Cutibacterium acnes FDAARGOS_503 AYZ25079.1    
 EGY06_04000   Cutibacterium acnes FDAARGOS_503 AYZ25080.1    
 EGX38_10250   Cutibacterium acnes FDAARGOS_577 AYW80831.1    
 EGX38_10255   Cutibacterium acnes FDAARGOS_577 AYW80832.1    
 EGX38_05645   Cutibacterium acnes FDAARGOS_577 AYW80051.1    
 TIA1EST1_03445   Cutibacterium acnes hdn-1 AID35562.1    
 TIA1EST1_07805   Cutibacterium acnes hdn-1 AID37120.1    
 TIA1EST1_03440 (fragment)   Cutibacterium acnes hdn-1 AID35561.1    
 PAGK_0621   Cutibacterium acnes HL096PA1 AGJ79469.1    
 PAGK_1443   Cutibacterium acnes HL096PA1 AGJ80267.1    
 PAGK_1444   Cutibacterium acnes HL096PA1 AGJ80268.1    
 DXN06_12345   Cutibacterium acnes KCOM 1315 AXM07790.1    
 DXN06_04215   Cutibacterium acnes KCOM 1315 AXM06433.1    
 DXN06_04210   Cutibacterium acnes KCOM 1315 AXM06432.1    
 RN83_03985   Cutibacterium acnes KCOM 1861 (= ChDC B594) ALD69359.1    
 RN83_03980   Cutibacterium acnes KCOM 1861 (= ChDC B594) ALD69358.1    
 RN83_08260   Cutibacterium acnes KCOM 1861 (= ChDC B594) ALD70051.1    
 sialidase (PPA1560)   Cutibacterium acnes KPA171202 AAT83304.1 Q6A7G1  
 PPA0685   Cutibacterium acnes KPA171202 AAT82441.1 Q6A9X5  
 PPA0684   Cutibacterium acnes KPA171202 AAT82440.1 Q6A9X6  
 ALW29_03475   Cutibacterium acnes PA_12_1_L1 ALT41780.1    
 ALW29_07860   Cutibacterium acnes PA_12_1_L1 ALT42513.1    
 ALW29_03480   Cutibacterium acnes PA_12_1_L1 ALT41781.1    
 ALW27_03490   Cutibacterium acnes PA_12_1_R1 ALT39544.1    
 ALW27_03485   Cutibacterium acnes PA_12_1_R1 ALT39543.1    
 ALW27_07840   Cutibacterium acnes PA_12_1_R1 ALT40274.1    
 ALW33_03630   Cutibacterium acnes PA_15_1_R1 ALT44065.1    
 ALW33_03625   Cutibacterium acnes PA_15_1_R1 ALT44064.1    
 ALW33_07890   Cutibacterium acnes PA_15_1_R1 ALT44783.1    
 ALW23_03630   Cutibacterium acnes PA_15_2_L1 ALT37265.1    
 ALW23_03635   Cutibacterium acnes PA_15_2_L1 ALT37266.1    
 ALW23_07985   Cutibacterium acnes PA_15_2_L1 ALT38000.1    
 ALW21_03495   Cutibacterium acnes PA_21_1_L1 ALT34956.1    
 ALW21_07890   Cutibacterium acnes PA_21_1_L1 ALT35678.1    
 ALW21_03500   Cutibacterium acnes PA_21_1_L1 ALT34957.1    
 ALW22_03520   Cutibacterium acnes PA_30_2_L1 ALT32700.1    
 ALW22_07885   Cutibacterium acnes PA_30_2_L1 ALT33417.1    
 ALW22_03515   Cutibacterium acnes PA_30_2_L1 ALT32699.1    
 HMPREF0675_4627   Cutibacterium acnes SK137 ADD98985.1 D4HFH3  
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