Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (4271); Uniprot accession (686); PDB accession (146); 3D entries (19); cryst (0)
All (3963) Archaea (1) Bacteria (3547) Eukaryota (381) Viruses (34) Structure (19) Characterized (96)
| 1 | ... | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | ... | 37 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 C1O30_17610   Dickeya zeae MS2 AUQ26749.1    
 C1O30_20680   Dickeya zeae MS2 AUQ27312.1    
 FH5T_01145   Draconibacterium orientale FH5 AHW58654.1    
 FH5T_13900   Draconibacterium orientale FH5 AHW60355.1    
 Dfer_2148   Dyadobacter fermentans DSM 18053 ACT93371.1 C6VYL6  
 Dfer_2863   Dyadobacter fermentans DSM 18053 ACT94078.1 C6W4H7  
 Dfer_3020   Dyadobacter fermentans DSM 18053 ACT94235.1 C6W5L7  
 DN752_14255   Echinicola strongylocentroti MEBiC08714 AWW31195.1    
 DN752_04810   Echinicola strongylocentroti MEBiC08714 AWW29506.1    
 neuraminidase   Echinicola vietnamensis DSM 17526 AGA76790.1    
 Echvi_1665   Echinicola vietnamensis DSM 17526 AGA77930.1    
 Echvi_4341   Echinicola vietnamensis DSM 17526 AGA80527.1    
 ETEE_3198 (fragment)   Edwardsiella anguillarum ET080813 AIJ09625.1    
 A9798_10455   Edwardsiella hoshinae ATCC 35051 AOV98594.1    
 ETAC_05915   Edwardsiella piscicida C07-087 AGH73308.1    
 BXA22_01835   Edwardsiella piscicida ETW41 ARD17174.1    
 A9797_06095   Edwardsiella piscicida S11-285 AOP42629.1    
 sialidase NanA   Edwardsiella tarda E01-21 BAV69399.1    
 NanA sialidase   Edwardsiella tarda E22 BAX03532.1    
 NanA sialidase   Edwardsiella tarda E381 BAV59436.1    
 ETAE_1245   Edwardsiella tarda EIB202 ACY84088.1 D0ZFQ6  
 ORF   Edwardsiella tarda ET-1 BAU80413.1    
 ETAF_1161   Edwardsiella tarda FL6-60 ADM41276.1 E0T4S6  
 sialidase (NanA)   Edwardsiella tarda FPC 498 BAP91033.1    
 NanA sialidase   Edwardsiella tarda NUF806 BAV59437.1    
 NanA sialidase   Edwardsiella tarda SU138 BAX36558.1    
 NanA sialidase   Edwardsiella tarda SU226 BAX03533.1    
 sialidase (NanA) 3.2.1.18 Edwardsiella tarda TX01 AFP73415.1    
 BBD33_05820   Elizabethkingia meningoseptica G4076 AQX04795.1    
 BBD35_07650   Elizabethkingia meningoseptica G4120 AQX12256.1    
 B5G46_05815   Elizabethkingia meningoseptica KC1913 AQX46837.1    
 NCTC10016_01251 (Neda_2)   Elizabethkingia meningoseptica NCTC10016 SQG06338.1    
 Emtol_2335   Emticicia oligotrophica DSM 17448 AFK03472.1    
 neuraminidase   Emticicia oligotrophica DSM 17448 AFK05157.1    
 neuraminidase   Emticicia oligotrophica DSM 17448 AFK05192.1    
 EZMO1_1737 (fragment)   Endozoicomonas montiporae CL-33 AMO55886.1    
 EZMO1_1736 (fragment)   Endozoicomonas montiporae CL-33 AMO55885.1    
 FA04_32600   Ensifer adhaerens Casida A ANK77378.1    
 OV14_b0333   Ensifer adhaerens OV14 AHK46900.1    
 SJ05684_c15290   Ensifer sojae CCBAU 05684 ASY62971.1    
 AB190_04710   Enterobacter asburiae CAV1043 AKK99904.1    
 A0R60_0918   Enterobacter asburiae ENIPBJ-CG1 AMX05225.1    
 Entas_2142   Enterobacter asburiae LF7a AEN64876.1    
 EC036_21440   Enterobacter cloacae GGT036 AIV29791.1    
 BFJ73_10280   Enterobacter cloacae isolate SBP-8 AOE95581.1    
 BJM06_02266   Enterobacter cloacae M12X01451 ASQ18057.1    
 B2J95_12170   Enterobacter cloacae Res2010EC27 AVL18757.1    
 ECL_02001   Enterobacter cloacae subsp. cloacae ATCC 13047 ADF61553.1 D5C8V6  
 A3UG_11160   Enterobacter cloacae subsp. dissolvens SDM AFM59966.1    
 AKI40_3003   Enterobacter sp. FY-07 AMO49388.1    
 C2U51_16240   Enterobacteriaceae bacterium ENNIH1 AUV02432.1    
 C2U51_09030   Enterobacteriaceae bacterium ENNIH1 AUV01143.1    
 C2U52_22480   Enterobacteriaceae bacterium ENNIH2 AUV08826.1    
 C2U55_19795   Enterobacteriaceae bacterium ENNIH3 AUU91156.1    
 neuraminidase   Enterobacteriaceae bacterium strain FGI 57 AGB78182.1    
 DVA44_12385   Enterobacteriaceae bacterium w17 AXF64845.1    
 DVA43_06655   Enterobacteriaceae bacterium w6 AXF59241.1    
 NCTC12421_02418 (NanB)   Enterococcus cecorum NCTC12421 SQE57351.1    
 neuraminidase   Enterococcus durans BDGP3 ASV96651.1    
 A4V06_00350   Enterococcus faecalis KB1 ANU71609.1
ASU26373.1
   
 A6B47_00790   Enterococcus faecalis sorialis ARV02485.1    
 CKA38_08560   Ereboglobus luteus Ho45 AWI09289.1    
 CKA38_10805   Ereboglobus luteus Ho45 AWI09673.1    
 CKA38_02915   Ereboglobus luteus Ho45 AWI08349.1    
 CKA38_02900   Ereboglobus luteus Ho45 AWI08346.1    
 CKA38_10255   Ereboglobus luteus Ho45 AWI09573.1    
 CKA38_12475   Ereboglobus luteus Ho45 AWI09953.1    
 CKA38_09970   Ereboglobus luteus Ho45 AWI09525.1    
 CKA38_02845   Ereboglobus luteus Ho45 AWI08336.1    
 CKA38_08285   Ereboglobus luteus Ho45 AWI10604.1    
 CKA38_09625   Ereboglobus luteus Ho45 AWI09472.1    
 CKA38_08295   Ereboglobus luteus Ho45 AWI09238.1    
 AV903_14285   Erwinia tracheiphila MDcuke AXF76944.1    
 sialidase (NanH) 3.2.1.18 Erysipelothrix rhusiopathiae FUJISAWA BAB40435.1 Q9AJR8  
 A2I91_08040   Erysipelothrix rhusiopathiae GXBY-1 AMS11685.1    
 DM789_01555   Erysipelothrix rhusiopathiae ML101 AWU40967.1    
 neuraminidase (Nanh.1)   Erysipelothrix rhusiopathiae str. Fujisawa BAK31357.1    
 neuraminidase   Erysipelothrix rhusiopathiae SY1027 AGN25301.1    
 BC346_07560   Erysipelothrix rhusiopathiae WH13013 AOO68185.1    
 CNQ55_18330   Escherichia coli 317 ATB79324.1    
 ECP_0693   Escherichia coli 536 ABG68721.1 Q0TK10  
 DNNLJILF_03926   Escherichia coli 81009 ART45114.1    
 ECABU_c07260   Escherichia coli ABU 83972 ADN45309.1 E1PBY9  
 L282_3503   Escherichia coli APEC IMT5155 AJB38462.1    
 APECO1_1391   Escherichia coli APEC O1 ABJ00080.1 A1A8U0  
 APECO18_22060   Escherichia coli APEC O18 AKK36639.1    
 AM344_26175   Escherichia coli AR_0017 ATY21957.1    
 AM437_12870   Escherichia coli AR_0058 ARX25195.1    
 AM460_22970   Escherichia coli AR_0081 AVN40800.1    
 AM483_16545   Escherichia coli AR_0104 ARA65015.1    
 CSC38_0410   Escherichia coli AR_451 AWZ79401.1    
 DR76_4325   Escherichia coli ATCC 25922 AIL17655.1    
 CDW44_03945   Escherichia coli BH100 ATV07895.1    
 BH100B_00737   Escherichia coli BH100 AUF89776.1    
 BH100L_00720   Escherichia coli BH100L AUQ36351.1    
 BH100N_00713   Escherichia coli BH100N AUN89175.1    
 AVR67_03670   Escherichia coli CD306 ALX51398.1    
 c0759   Escherichia coli CFT073 AAN79232.1    
 BWI82_23885   Escherichia coli Combat2C1 AUY73107.1    
 RG41_12390   Escherichia coli D8 APK34624.1    
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