Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); 2-keto-3-deoxynononic acid hydrolase (EC 3.2.1.-); anhydrosialidase (EC 4.2.2.15); 3-deoxy-D-manno-octulosonic-acid hydrolase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (3614); Uniprot accession (686); PDB accession (146); 3D entries (19); cryst (0)
All (3359) Archaea (1) Bacteria (2954) Eukaryota (371) Viruses (33) Structure (19) Characterized (96)
| 1 | ... | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | ... | 31 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 APT58_13045   Corynebacterium glutamicum USDA-ARS-USMARC-56828 AMA01077.1    
 BSP99_13380   Corynebacterium glutamicum XV APT08329.1    
 A3654_08265   Corynebacterium glutamicum YI ANE08356.1    
 C627_08425 (fragment)   Corynebacterium glutamicum ZL-6 ANR65645.1    
 C627_13015   Corynebacterium glutamicum ZL-6 ANR66531.1    
 C627_08430 (fragment)   Corynebacterium glutamicum ZL-6 ANR65646.1    
 ckrop_1872 (NanI)   Corynebacterium kroppenstedtii DSM 44385 ACR18588.1 C4LL83  
 CMUST_11800   Corynebacterium mustelae DSM 45274 AKK06671.1    
 CMUST_04910   Corynebacterium mustelae DSM 45274 AKK05320.1    
 CPHO_04675   Corynebacterium phocae M408/89/1 APT92300.1    
 Cp1002_0387   Corynebacterium pseudotuberculosis 1002 ADL20287.1 D9Q6J2  
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis 1002B ALM77000.1    
 Cp12C_0413 (NanH)   Corynebacterium pseudotuberculosis 12C AKJ55057.1    
 Cp226_0402 (NanH)   Corynebacterium pseudotuberculosis 226 AKC73144.1    
 Cp258_0396 (NanH)   Corynebacterium pseudotuberculosis 258 AJF93848.1    
 Cp262_0396 (NanH)   Corynebacterium pseudotuberculosis 262 AKP08063.2    
 Cp267_0402 (NanH)   Corynebacterium pseudotuberculosis 267 AFH51310.1    
 Cp29156_0391 (NanH)   Corynebacterium pseudotuberculosis 29156 AKI58795.1    
 Cp3995_0391 (NanH)   Corynebacterium pseudotuberculosis 3/99-5 AEX38862.1    
 Cp31_0399 (NanH)   Corynebacterium pseudotuberculosis 31 AKN59634.1    
 A4R72_02270   Corynebacterium pseudotuberculosis 32 APB10365.1    
 A4R71_02285   Corynebacterium pseudotuberculosis 33 APB12413.1    
 A4R69_02280   Corynebacterium pseudotuberculosis 34 APB28708.1    
 A4R68_02280   Corynebacterium pseudotuberculosis 35 APB14459.1    
 A4R67_02275   Corynebacterium pseudotuberculosis 36 APB16504.1    
 A4R66_02280   Corynebacterium pseudotuberculosis 38 APB18553.1    
 A4R65_02275   Corynebacterium pseudotuberculosis 39 APB20594.1    
 Cp4202_0383 (NanH)   Corynebacterium pseudotuberculosis 42/02-A AEP69653.1    
 A4R64_02065   Corynebacterium pseudotuberculosis 43 APB22605.1    
 A4R63_02065   Corynebacterium pseudotuberculosis 46 APB24617.1    
 A4R62_02280   Corynebacterium pseudotuberculosis 48 APB26663.1    
 CPTA_00924   Corynebacterium pseudotuberculosis 48252 AIG06753.1    
 CpATCC19410_0424 (NanH)   Corynebacterium pseudotuberculosis ATCC 19410 ARS59917.1    
 CpC231_0390   Corynebacterium pseudotuberculosis C231 ADL09880.1 D9QEF7  
 CpCIP5297_0398 (NanH)   Corynebacterium pseudotuberculosis CIP 52.97 ART29233.1    
 CpCP13_0395 (NanH)   Corynebacterium pseudotuberculosis Cp13 ANQ76571.1    
 Cp162_0386 (NanH)   Corynebacterium pseudotuberculosis Cp162 ASA48272.1    
 CPTB_00609   Corynebacterium pseudotuberculosis CS_10 AIG08665.1    
 CpE19_0406 (NanH)   Corynebacterium pseudotuberculosis E19 AKS12747.1    
 CpE55_0408 (NanH)   Corynebacterium pseudotuberculosis E55 ANH23162.1    
 AN398_01935   Corynebacterium pseudotuberculosis E56 ALU20970.1    
 cpfrc_00386 (NanH)   Corynebacterium pseudotuberculosis FRC41 ADK28179.1 D8KKR2  
 CPTC_00270   Corynebacterium pseudotuberculosis Ft_2193/67 AIG10558.1    
 CpI19_0389   Corynebacterium pseudotuberculosis I19 ADO25673.1 E3F6P0  
 CPI37_0433 (NanH)   Corynebacterium pseudotuberculosis I37 APG81124.1    
 ATN02_02505   Corynebacterium pseudotuberculosis MB11 AMN69475.1    
 ATN03_02065   Corynebacterium pseudotuberculosis MB14 AMN71321.1    
 BFF97_00416 (NanH)   Corynebacterium pseudotuberculosis MB154 ATV79183.1    
 BFF96_0431 (NanH)   Corynebacterium pseudotuberculosis MB278 ATB61326.1    
 ATN04_06525   Corynebacterium pseudotuberculosis MB30 AMN74028.1    
 BFG01_002080 (NanH)   Corynebacterium pseudotuberculosis MB302 ASC74753.1    
 ATN05_02060   Corynebacterium pseudotuberculosis MB66 AMN75223.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis MEX1 APZ31168.1    
 AN397_01940   Corynebacterium pseudotuberculosis MEX25 ALU16985.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis MEX29 APA72139.1    
 CpMEX30_0432 (NanH)   Corynebacterium pseudotuberculosis MEX30 APQ53533.1    
 CpMEX31_0432 (NanH)   Corynebacterium pseudotuberculosis MEX31 APQ55593.1    
 CpMEX9_0403 (NanH)   Corynebacterium pseudotuberculosis MEX9 ANH25216.1    
 CpMIC6_0417 (NanH)   Corynebacterium pseudotuberculosis MIC6 AQU92087.1    
 CpN1_0402 (NanH)   Corynebacterium pseudotuberculosis N1 ALP33124.1    
 CpP54B96_0391 (NanH)   Corynebacterium pseudotuberculosis P54B96 AFF21544.1    
 CpPA01_0371 (NanH)   Corynebacterium pseudotuberculosis PA01 ALR33038.1    
 CpPA02_0369 (NanH)   Corynebacterium pseudotuberculosis PA02 ANK55784.1    
 CpPA04_0393   Corynebacterium pseudotuberculosis PA04 AQL50505.1    
 CpPA05_02990   Corynebacterium pseudotuberculosis PA05 APX35569.1    
 CpPA06_02430   Corynebacterium pseudotuberculosis PA06 APX37410.1    
 CpPA07_0394 (NanH)   Corynebacterium pseudotuberculosis PA07 ATQ64714.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis PA08; A19 ATQ80695.1    
 CpPAT10_0391 (NanH)   Corynebacterium pseudotuberculosis PAT10 AEK91723.1    
 neuraminidase (NanH)   Corynebacterium pseudotuberculosis phoP AQU90003.1    
 AK970_01940   Corynebacterium pseudotuberculosis PO222/4-1 ALU18978.1    
 AN902_01950   Corynebacterium pseudotuberculosis PO269-5 ALF56960.1    
 CpSigmaE_0400 (NanH)   Corynebacterium pseudotuberculosis SigmaE ARB41976.1    
 CpT1_0395 (NanH)   Corynebacterium pseudotuberculosis T1 ANQ78695.1    
 CpVD57_0395 (NanH)   Corynebacterium pseudotuberculosis VD57 AJC13124.1    
 CTEST_12930 (NanI)   Corynebacterium testudinoris DSM 44614 AKK09989.1    
 CULC0102_0481 (NanH)   Corynebacterium ulcerans 0102 BAM26683.1    
 Cul05146_0470 (NanH)   Corynebacterium ulcerans 05146 AIU91055.1    
 Cul131001_0462 (NanH)   Corynebacterium ulcerans 131001 ALD94188.1    
 CUL131002_0438 (NanH)   Corynebacterium ulcerans 131002 AKA95986.1    
 Cul210931_0440 (NanH)   Corynebacterium ulcerans 210931 AIU29801.1    
 Cul210932_0455 (NanH)   Corynebacterium ulcerans 210932 AIT88419.1    
 CULC809_00434 (NanH)   Corynebacterium ulcerans 809 AEG80974.1    
 CULC22_00437 (NanH)   Corynebacterium ulcerans BR-AD22 AEG83155.1    
 CulFRC11_0435 (NanH)   Corynebacterium ulcerans FRC11 AIU32028.1    
 CulFRC58_0499 (NanH)   Corynebacterium ulcerans FRC58 AKN76353.1    
 SAMEA4504038_01773 (NanH)   Corynebacterium ulcerans NCTC7910 SNV12433.1    
 CBE74_02420   Corynebacterium ulcerans PO100/5 ARU45544.1    
 CUTER_01555   Corynebacterium uterequi DSM 45634 AKK10327.1    
 CUTER_03660   Corynebacterium uterequi DSM 45634 AKK10740.1    
 CUTER_01485   Corynebacterium uterequi DSM 45634 AKK10313.1    
 BKK80_26820   Cupriavidus sp. USMAA1020 AOZ09393.1    
 BKK79_32725   Cupriavidus sp. USMAA2-4 AOY96358.1    
 BKK81_29535   Cupriavidus sp. USMAHM13 AOZ03243.1    
 Csp_A02540   Curvibacter putative symbiont of Hydra magnipapillata CBA27491.1 C9Y803  
 AEP_03366   Curvibacter sp. AEP1-3 ARV20288.1    
 VO62_03330   Cutibacterium acnes A1-14 ALU23131.1    
 VO62_07505   Cutibacterium acnes A1-14 ALU23799.1    
 VO62_03325   Cutibacterium acnes A1-14 ALU23130.1    
 RN83_03985   Cutibacterium acnes KCOM 1861 (= ChDC B594) ALD69359.1    
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