Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); 2-keto-3-deoxynononic acid hydrolase (EC 3.2.1.-); anhydrosialidase (EC 4.2.2.15); 3-deoxy-D-manno-octulosonic-acid hydrolase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (3514); Uniprot accession (686); PDB accession (144); 3D entries (19); cryst (0)
All (3255) Archaea (1) Bacteria (2851) Eukaryota (371) Viruses (32) Structure (19) Characterized (96)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 30 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 BJS_06052   Bradyrhizobium japonicum SEMIA 5079 AHY52385.1    
 BJ6T_70870   Bradyrhizobium japonicum USDA 6 BAL12336.1    
 BN2626_G22_7129   Bradyrhizobium sp. CUU20713.1    
 sialidase   Brevibacterium casei LHS-SIA ADU02857.1    
 YH66_08205   [Brevibacterium] flavum ATCC 15168 AKF27527.1    
 C628_08520 (fragment)   [Brevibacterium] flavum ZL-1 ANR62642.1    
 C628_08525 (fragment)   [Brevibacterium] flavum ZL-1 ANR62643.1    
 C628_13140   [Brevibacterium] flavum ZL-1 ANR63525.1    
 neuraminidase   Brevibacterium sandarakinum DSM 22082 SDS24506.1    
 BamMC406_5961   Burkholderia ambifaria MC40-6 ACB68397.1 B1Z3T4  
 A2T82_32005   Burkholderia cenocepacia 842 AMU10945.1    
 Bcen_1532   Burkholderia cenocepacia AU 1054 ABF76437.1 Q1BVB8  
 BHQ31_30220   Burkholderia cenocepacia CR318 AQT54433.1    
 Bcen2424_6297   Burkholderia cenocepacia HI2424 ABK13029.1 A0KCW6  
 Bcenmc03_6956   Burkholderia cenocepacia MC0-3 ACA96057.1    
 A8E96_00585   Burkholderia cenocepacia VC12802 AQQ30985.1    
 bglu_2g15160   Burkholderia glumae BGR1 ACR31872.1 C5AIZ2  
 KS03_4421   Burkholderia glumae LMG 2196 = ATCC 33617 AJY64192.1    
 BC1001_1190   Burkholderia sp. CCGE1001 ADX54633.1    
 CLDAP_34930   Caldilinea aerophila DSM 14535 = NBRC 104270 BAM01533.1    
 neuraminidase   Campylobacter avium LMG 24591 ASQ30906.1    
 Acid_0193   Candidatus Solibacter usitatus Ellin6076 ABJ81207.1 Q02CK9  
 Acid_2658   Candidatus Solibacter usitatus Ellin6076 ABJ83647.1 Q024C9  
 Acid_4606   Candidatus Solibacter usitatus Ellin6076 ABJ85565.1 Q01XQ0  
 CGC47_09295   Capnocytophaga canimorsus 7120 ATA77758.1    
 sialidase (SiaC;CAPCAMM2a;Ccan_04790) 3.2.1.18 Capnocytophaga canimorsus Cc5 AEK22601.1
ACA13563.1
B5SV83  
 CGC54_09290   Capnocytophaga canimorsus H3936 ATA94514.1    
 CGC56_09595   Capnocytophaga canimorsus H5594 ATA92391.1    
 CGC48_07785   Capnocytophaga cynodegmi G7591 ATA68541.1    
 AXF12_04465   Capnocytophaga haemolytica CCUG 32990 AMD84831.1    
 SAMEA44541418_00838 (NedA)   Capnocytophaga haemolytica NCTC12947 SNV06988.1    
 CGC53_01515   Capnocytophaga leadbetteri H6253 ATA82886.1    
 Coch_0016   Capnocytophaga ochracea DSM 7271 ACU91582.1 C7M450  
 CBG49_07560   Capnocytophaga sp. ChDC OS43 ASF42938.1    
 CGC52_04655   Capnocytophaga sp. H2931 ATA74786.1    
 CGC49_04875   Capnocytophaga sp. H4358 ATA72686.1    
 AM608_03550   Capnocytophaga sp. oral taxon 323 str. F0383 ALC96795.1    
 CGC57_12040   Capnocytophaga sputigena D1176 ATA71584.1    
 CGC59_13335   Capnocytophaga sputigena H4486 ATA80591.1    
 CGC55_03795   Capnocytophaga sputigena KC1668 ATA83690.1    
 CGC58_04400   Capnocytophaga stomatis H2177 ATA89020.1    
 LK04_16920   Cedecea neteri ND02 ALV93729.1    
 LH89_13075   Cedecea neteri ND14b AIR70090.1    
 LH89_16250   Cedecea neteri ND14b AIR70683.1    
 sialidase   Cellulosimicrobium cellulans 21 ANR02616.1    
 CBR64_08430   Cellulosimicrobium cellulans PSBB019 ARU51502.1    
 B8281_03265   Cellulosimicrobium sp. TH-20 ARK03899.1    
 Z042_19405   Chania multitudinisentens RB-25 AHG21530.1    
 Cpin_1807   Chitinophaga pinensis DSM 2588 ACU59303.1 C7PA66  
 neuraminidase   Chitinophaga pinensis DSM 2588 ACU64580.1 C7PTY5  
 CA1H_7101 (fragment)   Chlamydia abortus 1H CED81651.1    
 AB7_7101 (fragment)   Chlamydia abortus AB7 CED80691.1
CEF17097.1
   
 CAB1_0654   Chlamydia abortus LLG EGK69379.1    
 CPS0A_0729   Chlamydia psittaci 01DC11 AEG86676.1    
 BN356_6571   Chlamydia psittaci 01DC12 CCO02158.1    
 CPS0B_0720   Chlamydia psittaci 02DC15 AEG87654.1    
 CPS0D_0725   Chlamydia psittaci 08DC60 AEG88627.1    
 CPSIT_0711   Chlamydia psittaci 6BC ADZ18791.1
AEB55681.1
   
 B595_0770   Chlamydia psittaci 84/55 AFS19729.1    
 CPS0C_0726   Chlamydia psittaci C19/98 AEG85701.1    
 B711_0772   Chlamydia psittaci CP3 AFS27165.1    
 B598_0713   Chlamydia psittaci GR9 AFS20791.1    
 B602_0720   Chlamydia psittaci M56 AFS24928.1    
 AO9_03425   Chlamydia psittaci Mat116 AGE75243.1    
 B599_0718   Chlamydia psittaci MN AFS21540.1    
 B712_0716   Chlamydia psittaci NJ1 AFS28225.1    
 Cpsi_6531   Chlamydia psittaci RD1 CBY17171.1 E5AIE1  
 B600_0767   Chlamydia psittaci VS225 AFS22917.1    
 B603_0723   Chlamydia psittaci WC AFS25884.1    
 B601_0714   Chlamydia psittaci WS/RT/E30 AFS24251.1    
 ROD_15131   Citrobacter rodentium ICC168 CBG88277.1 D2TIF0  
 CLS_13500   [Clostridium] cf. saccharolyticum K10 CBK76990.1 D6DH16  
 BTM20_05845   Clostridium chauvoei 12S0467 ATD54786.1    
 BTM21_07215   Clostridium chauvoei DSM 7528 ATD57534.1    
 NanA (fragment)   Clostridium chauvoei JF3703 CAR82360.1 E1UGY3  
 sialidase (NanA) (fragment) 3.2.1.18 Clostridium chauvoei JF4135 CAR82361.1 E1UGY4  
 CCH01_10370   Clostridium chauvoei JF4335 SLK16343.1    
 sialidase 1 'small' 3.2.1.18 Clostridium perfringens A99 CAA68780.1 P10481  
 exo-α-sialidase 'large' (NanH) 3.2.1.18 Clostridium perfringens A99 CAA60796.1 Q59310  
 sialidase 2 (NanH) 3.2.1.18 Clostridium perfringens ATCC 10543 CAA50436.1 Q59311  
 sialidase (CpNanI;CPF_0721) 3.2.1.18 Clostridium perfringens ATCC 13124 ABG83208.1 Q0TT67 4L2E[A]
5TSP[A,B]
 CPF_0985   Clostridium perfringens ATCC 13124 ABG84018.1 Q0TSF8  
 CPF_0532   Clostridium perfringens ATCC 13124 ABG84247.1 Q0TTQ4  
 BXT91_02895   Clostridium perfringens CP15 AQW22891.1    
 BXT91_04080   Clostridium perfringens CP15 AQW23115.1    
 BXT91_05085   Clostridium perfringens CP15 AQW23307.1    
 BXT94_04320   Clostridium perfringens Del1 AQW26025.1    
 BXT94_09915   Clostridium perfringens Del1 AQW27075.1    
 BXT94_05545   Clostridium perfringens Del1 AQW26258.1    
 BG908_09070   Clostridium perfringens EHE-NE18 ASY51800.1    
 BG908_04100   Clostridium perfringens EHE-NE18 ASY50870.1    
 BG908_02920   Clostridium perfringens EHE-NE18 ASY50649.1    
 BG908_05115   Clostridium perfringens EHE-NE18 ASY51063.1    
 FORC3_0555   Clostridium perfringens FORC_003 ALG47932.1    
 FORC3_1686   Clostridium perfringens FORC_003 ALG49063.1    
 FORC3_0922   Clostridium perfringens FORC_003 ALG48299.1    
 FORC3_0721   Clostridium perfringens FORC_003 ALG48098.1    
 FORC25_0523   Clostridium perfringens FORC_025 AOY52943.1    
 FORC25_0716   Clostridium perfringens FORC_025 AOY53136.1    
 FORC25_0968   Clostridium perfringens FORC_025 AOY53385.1    
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