Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (5124); Uniprot accession (686); PDB accession (146); 3D entries (19); cryst (0)
All (4887) Archaea (1) Bacteria (4436) Eukaryota (390) Viruses (34) unclassified (26) Structure (19) Characterized (96)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 46 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 GV66_09220   Bacteroides dorei isolate HS1_L3_B_079 AII67866.1    
 GV66_14125   Bacteroides dorei isolate HS1_L3_B_079 AII68768.1    
 GV66_22035   Bacteroides dorei isolate HS1_L3_B_079 AII70179.1    
 IY41_14770   Bacteroides dorei isolate HS2_L_2_B_045b ALA76192.1    
 IY41_22375   Bacteroides dorei isolate HS2_L_2_B_045b ALA75889.1    
 IY41_09195   Bacteroides dorei isolate HS2_L_2_B_045b ALA73618.1    
 BF638R_4097 (NanH2)   Bacteroides fragilis 638R CBW24534.1 E1WPI1  
 BF638R_1728 (NanH)   Bacteroides fragilis 638R CBW22254.1 E1WUA2  
 BF638R_3784   Bacteroides fragilis 638R CBW24233.1 E1WMX5  
 BF638R_2942   Bacteroides fragilis 638R CBW23425.1 E1WS95  
 BF638R_3785   Bacteroides fragilis 638R CBW24234.1 E1WMX6  
 MB0529_01600   Bacteroides fragilis BE1 CUA18247.1    
 MB0529_03665   Bacteroides fragilis BE1 CUA20274.1    
 MB0529_02769   Bacteroides fragilis BE1 CUA19389.1    
 MB0529_03664 (NedA)   Bacteroides fragilis BE1 CUA20273.1    
 MB0529_03980 (NanH)   Bacteroides fragilis BE1 CUA20564.1    
 VU15_17650   Bacteroides fragilis BOB25 AKA53347.1    
 VU15_13185   Bacteroides fragilis BOB25 AKA52559.1    
 VU15_19555   Bacteroides fragilis BOB25 AKA53665.1    
 VU15_07340   Bacteroides fragilis BOB25 AKA51541.1    
 VU15_17645   Bacteroides fragilis BOB25 AKA53346.1    
 E0L14_19465   Bacteroides fragilis CCUG4856T QCT79443.1    
 E0L14_02390   Bacteroides fragilis CCUG4856T QCT76317.1    
 E0L14_00485   Bacteroides fragilis CCUG4856T QCT75992.1    
 E0L14_00480   Bacteroides fragilis CCUG4856T QCT75991.1    
 E0L14_13305   Bacteroides fragilis CCUG4856T QCT78323.1    
 EC81_012955   Bacteroides fragilis DCMOUH0017B QCQ54650.1    
 EC81_007430   Bacteroides fragilis DCMOUH0017B QCQ53656.1    
 EC81_020165   Bacteroides fragilis DCMOUH0017B QCQ56765.1    
 EC81_000630   Bacteroides fragilis DCMOUH0017B QCQ52448.1    
 EC81_000625   Bacteroides fragilis DCMOUH0017B QCQ52447.1    
 EE52_018810   Bacteroides fragilis DCMOUH0018B QCQ51293.1    
 EE52_012255   Bacteroides fragilis DCMOUH0018B QCQ52211.1    
 HR50_018955   Bacteroides fragilis DCMOUH0042B QCQ42527.1    
 HR50_000460   Bacteroides fragilis DCMOUH0042B QCQ39187.1    
 HR50_012330   Bacteroides fragilis DCMOUH0042B QCQ41348.1    
 HR50_000465   Bacteroides fragilis DCMOUH0042B QCQ39188.1    
 IA74_019020   Bacteroides fragilis DCMOUH0067B QCQ39035.1    
 IA74_011625   Bacteroides fragilis DCMOUH0067B QCQ36714.1    
 IB64_013250   Bacteroides fragilis DCMOUH0085B QCQ32531.1    
 IB64_018965   Bacteroides fragilis DCMOUH0085B QCQ34569.1    
 EC80_012430   Bacteroides fragilis DCMSKEJBY0001B QCQ45602.1    
 EC80_019060   Bacteroides fragilis DCMSKEJBY0001B QCQ47658.1    
 EC80_000485   Bacteroides fragilis DCMSKEJBY0001B QCQ43461.1    
 EC80_000490   Bacteroides fragilis DCMSKEJBY0001B QCQ43462.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-1 ANG58842.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-10 ANG58849.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-2 ANG58843.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-4 ANG58844.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-8 ANG58847.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-9 ANG58848.1    
 BF1806 (Nanh)   Bacteroides fragilis NCTC 9343 CAH07505.1 Q5LEE6  
 BF3709   Bacteroides fragilis NCTC 9343 CAH09389.1 Q5L943  
 BF4051 (Nanh2)   Bacteroides fragilis NCTC 9343 CAH09725.1 Q5L868  
 BUN20_11375   Bacteroides fragilis Q1F2 AUI49199.1    
 BUN20_05835   Bacteroides fragilis Q1F2 AUI46163.1    
 AE940_04785   Bacteroides fragilis S14 ANQ60189.1    
 AE940_14190   Bacteroides fragilis S14 ANQ61855.1    
 AE940_10415   Bacteroides fragilis S14 ANQ61181.1    
 AE940_14185   Bacteroides fragilis S14 ANQ61854.1    
 BF3099   Bacteroides fragilis YCH46 BAD49844.1    
 BF3937   Bacteroides fragilis YCH46 BAD50679.1    
 BF4242   Bacteroides fragilis YCH46 BAD50984.1 Q64NE9  
 BF3936   Bacteroides fragilis YCH46 BAD50678.1 Q64PA3  
 sialidase (BF1729) 3.2.1.18 Bacteroides fragilis YCH46 BAA05853.1
AAA22912.1
BAC56895.1
BAC56895.2
BAD48476.1
P31206
P31206
 
 Bache_2784   Bacteroides helcogenes P 36-108 ADV44727.1    
 Bache_1478   Bacteroides helcogenes P 36-108 ADV43483.1    
 Bache_2002   Bacteroides helcogenes P 36-108 ADV43976.1    
 C3V43_10350   Bacteroides heparinolyticus F0111 AVM58107.1    
 C3V43_10330 (fragment)   Bacteroides heparinolyticus F0111 AVM58103.1    
 Bovatus_01543 (Neda_2)   Bacteroides ovatus ATCC 8483 ALJ46187.1    
 Bovatus_01539 (Neda_1)   Bacteroides ovatus ATCC 8483 ALJ46183.1    
 Bovatus_00599 (NanB)   Bacteroides ovatus ATCC 8483 ALJ45265.1    
 Bovatus_00310   Bacteroides ovatus ATCC 8483 ALJ44981.1    
 Bovatus_04939 (Pkn1_3)   Bacteroides ovatus ATCC 8483 ALJ49526.1    
 BACOV975_03113 (NanH)   Bacteroides ovatus V975 SCV09319.1    
 BACOV975_04337   Bacteroides ovatus V975 SCV10543.1    
 BACOV975_03396   Bacteroides ovatus V975 SCV09602.1    
 BACOV975_04333   Bacteroides ovatus V975 SCV10539.1    
 BACOV975_02744   Bacteroides ovatus V975 SCV08950.1    
 Bacsa_2222   Bacteroides salanitronis DSM 18170 ADY36775.1    
 Bacsa_3464   Bacteroides salanitronis DSM 18170 ADY37989.1    
 Btheta7330_02628 (NanB)   Bacteroides thetaiotaomicron 7330 ALJ42170.1    
 Btheta7330_02907   Bacteroides thetaiotaomicron 7330 ALJ42444.1    
 bimodular α-1,5-rhamnosidase / α-2,3-KDO-hydrolase (BT1013) 3.2.1.40
3.2.1.-
Bacteroides thetaiotaomicron VPI-5482 AAO76120.1
NP_809926.1
Q8A904  
 sialidase (BtsA;BTSA;BT0455) 3.2.1.18 Bacteroides thetaiotaomicron VPI-5482 AAO75562.1
NP_809368.1
Q8AAK9 4BBW[A]
 BVU_1801   Bacteroides vulgatus ATCC 8482 ABR39477.1 A6L1B3  
 BVU_2645   Bacteroides vulgatus ATCC 8482 ABR40297.1 A6L3N3  
 BVU_4143   Bacteroides vulgatus ATCC 8482 ABR41745.1 A6L7T1  
 BvMPK_2334   Bacteroides vulgatus mpk ALK84931.1    
 BvMPK_0225   Bacteroides vulgatus mpk ALK82864.1    
 BvMPK_3663   Bacteroides vulgatus mpk ALK86224.1    
 BXY_44750   Bacteroides xylanisolvens XB1A CBK69352.1 D6D4V8  
 BXY_06360   Bacteroides xylanisolvens XB1A CBK65853.1 D6D758  
 BXY_09340   Bacteroides xylanisolvens XB1A CBK66099.1 D6D7V4  
 BXY_44710   Bacteroides xylanisolvens XB1A CBK69348.1 D6D4V4  
 C4H11_09345   Bacteroides zoogleoformans ATCC 33285 AVM54056.1    
 C4H11_13210   Bacteroides zoogleoformans ATCC 33285 AVM54135.1    
 BARVI_04125   Barnesiella viscericola DSM 18177 AHF12110.1    
 BARVI_05470   Barnesiella viscericola DSM 18177 AHF12313.1    
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