Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (5231); Uniprot accession (686); PDB accession (146); 3D entries (19); cryst (0)
All (4988) Archaea (1) Bacteria (4552) Eukaryota (395) Viruses (34) unclassified (6) Structure (19) Characterized (96)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 47 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 C1O50_08765 (fragment)   Akkermansia muciniphila AMDK-15 QAA53276.1    
 C1O51_05820   Akkermansia muciniphila AMDK-16 QAA55051.1    
 C1O51_10265   Akkermansia muciniphila AMDK-16 QAA55849.1    
 C1O51_08765 (fragment)   Akkermansia muciniphila AMDK-16 QAA55584.1    
 C1O54_10245   Akkermansia muciniphila AMDK-17 QAA58164.1    
 C1O54_08735 (fragment)   Akkermansia muciniphila AMDK-17 QAA57899.1    
 C1O54_05825   Akkermansia muciniphila AMDK-17 QAA57370.1    
 C1O57_08790 (fragment)   Akkermansia muciniphila AMDK-18 QAA60226.1    
 C1O57_05815   Akkermansia muciniphila AMDK-18 QAA59682.1    
 C1O57_10300   Akkermansia muciniphila AMDK-18 QAA60492.1    
 C1O59_03550   Akkermansia muciniphila AMDK-19 QAA61630.1    
 C1O59_09940   Akkermansia muciniphila AMDK-19 QAA62761.1    
 C1O59_08450   Akkermansia muciniphila AMDK-19 QAA62497.1    
 CUC06_03470   Akkermansia muciniphila AMDK-2 AYR34527.1    
 CUC06_08355   Akkermansia muciniphila AMDK-2 AYR35383.1    
 CUC06_09895   Akkermansia muciniphila AMDK-2 AYR35657.1    
 C1O60_08475   Akkermansia muciniphila AMDK-20 QAA64727.1    
 C1O60_09990   Akkermansia muciniphila AMDK-20 QAA64994.1    
 C1O60_03580   Akkermansia muciniphila AMDK-20 QAA63881.1    
 C1O61_10120   Akkermansia muciniphila AMDK-21 QAA67259.1    
 C1O61_03635   Akkermansia muciniphila AMDK-21 QAA66136.1    
 C1O61_08590   Akkermansia muciniphila AMDK-21 QAA66993.1    
 C1O62_10060   Akkermansia muciniphila AMDK-22 QAA69513.1    
 C1O62_03570   Akkermansia muciniphila AMDK-22 QAA68391.1    
 C1O62_08535 (fragment)   Akkermansia muciniphila AMDK-22 QAA69252.1    
 CUB96_00625   Akkermansia muciniphila AMDK-3 AYR29523.1    
 CUB96_00635   Akkermansia muciniphila AMDK-3 AYR29525.1    
 CUB96_07585   Akkermansia muciniphila AMDK-3 AYR30712.1    
 CUB96_06005   Akkermansia muciniphila AMDK-3 AYR30437.1    
 CUC01_09080   Akkermansia muciniphila AMDK-4 AYR33215.1    
 CUC01_10635   Akkermansia muciniphila AMDK-4 AYR33496.1    
 CUC01_03840   Akkermansia muciniphila AMDK-4 AYR32309.1    
 CUC01_03830   Akkermansia muciniphila AMDK-4 AYR32307.1    
 C1I88_03465   Akkermansia muciniphila AMDK-7 QAA36040.1    
 C1I88_03475   Akkermansia muciniphila AMDK-7 QAA36042.1    
 C1I88_10230   Akkermansia muciniphila AMDK-7 QAA37241.1    
 C1I88_08450 (fragment)   Akkermansia muciniphila AMDK-7 QAA36920.1    
 C1I90_08625   Akkermansia muciniphila AMDK-8 QAA39295.1    
 C1I90_10365   Akkermansia muciniphila AMDK-8 QAA39604.1    
 C1I90_03780   Akkermansia muciniphila AMDK-8 QAA38454.1    
 Amuc_1547   Akkermansia muciniphila ATCC BAA-835 ACD05368.1    
 Amuc_0623   Akkermansia muciniphila ATCC BAA-835 ACD04460.1    
 Amuc_0625   Akkermansia muciniphila ATCC BAA-835 ACD04462.1 B2UPI5  
 Amuc_1835   Akkermansia muciniphila ATCC BAA-835 ACD05653.1 B2UN42  
 AKKM5201_04045   Akkermansia muciniphila CBA5201 QAT91178.1    
 AKKM5201_09010   Akkermansia muciniphila CBA5201 QAT92058.1    
 AKKM5201_10725   Akkermansia muciniphila CBA5201 QAT92361.1    
 AKKM5201_04055   Akkermansia muciniphila CBA5201 QAT91180.1    
 SI90_03070   Akkermansia muciniphila H2 QAR49693.1    
 SI90_00160   Akkermansia muciniphila H2 QAR49252.1    
 A4V05_03295   Akkermansia muciniphila YL44 ANU60534.1
ASB36178.1
   
 A4V05_05020   Akkermansia muciniphila YL44 ANU60847.1
ANU60847.2
ASB34341.1
   
 A4V05_10410   Akkermansia muciniphila YL44 ANU61810.1
ASB35300.1
   
 A4V05_10420   Akkermansia muciniphila YL44 ANU61812.1
ANU61812.2
ASB35302.1
   
 ABO_1915   Alcanivorax borkumensis SK2 CAL17363.1 Q0VN85  
 B5T_01121   Alcanivorax dieselolei B5 MCCC 1A00001 AFT69404.1    
 S7S_13465   Alcanivorax pacificus W11-5 AJD49105.1    
 CEK62_21655   Alcanivorax sp. N3-2A ASK36962.1    
 CEK62_01460   Alcanivorax sp. N3-2A ASK33144.1    
 AS19_19780   Alcanivorax sp. NBRC 101098 BAP14829.1    
 P40_05315   Alcanivorax xenomutans P40 ARB44919.1    
 neuraminidase   Algoriphagus sp. M8-2 AMQ58104.1    
 AO498_15680   Algoriphagus sp. M8-2 AMQ57894.1    
 AO498_15700   Algoriphagus sp. M8-2 AMQ57898.1    
 neuraminidase (NanH)   Alistipes sp. 5CPEGH6 BBL05903.1    
 ORF   Alloactinosynnema sp. L-07 CRK56629.1    
 SAMN04489726_7712   Allokutzneria albata DSM 44149 SDN67662.1    
 neuraminidase   Aminobacter sp. MSH1 AWC21155.1    
 A4R43_01560   Amycolatopsis albispora WP1 AXB41369.1    
 A4R43_04030   Amycolatopsis albispora WP1 AXB41796.1    
 A4R43_06755   Amycolatopsis albispora WP1 AXB42267.1    
 A4R43_37780   Amycolatopsis albispora WP1 AXB47503.1    
 AJAP_24045   Amycolatopsis japonica MG417-CF17 AIG77658.1    
 SAMN04489733_2798   Amycolatopsis keratiniphila FH 1893 SDU29546.1    
 neuraminidase   Amycolatopsis lurida NRRL 2430 AJK58915.1    
 neuraminidase   Amycolatopsis mediterranei RB AGT84773.1    
 neuraminidase   Amycolatopsis mediterranei S699 AEK42715.1
AFO77645.1
   
 AMED_4157 (Neu)   Amycolatopsis mediterranei U32 ADJ45934.1 D8HR32  
 neuraminidase   Amycolatopsis methanolica 239 AIJ25416.1    
 neuraminidase   Amycolatopsis orientalis B-37 ANN16941.1    
 AORI_5269   Amycolatopsis orientalis HCCB10007 AGM07852.1    
 CU254_13445   Amycolatopsis sp. AA4 ATY11350.1    
 CU254_27865   Amycolatopsis sp. AA4 ATY16653.1    
 neuraminidase   Amycolatopsis sp. BJA-103 AUI58079.1    
 BEQ56_05740   Anaerolineaceae bacterium oral taxon 439 W11661 AOH43019.1    
 ANTHELSMS3_04479   Antarctobacter heliothermus SMS3 ASP23079.1    
 neuraminidase   Aquiflexum balticum DSM 16537 SMD43125.1    
 SAMN00777080_0072   Aquiflexum balticum DSM 16537 SMD41548.1    
 D6B99_08590   Arachidicoccus sp. KIS59-12 AYD47657.1    
 D6B99_12625   Arachidicoccus sp. KIS59-12 AYD48371.1    
 Arch_0026   Arcanobacterium haemolyticum DSM 20595 ADH91794.1 D7BLJ5  
 Arch_1299   Arcanobacterium haemolyticum DSM 20595 ADH93004.1 D7BK24  
 NCTC8452_00740 (Neda_2)   Arcanobacterium haemolyticum NCTC8452 SQH28241.1    
 NCTC8452_00161 (Neda_1)   Arcanobacterium haemolyticum NCTC8452 SQH27393.1    
 EBF03_00135   Arcanobacterium haemolyticum SCDR 1 QCX45996.1    
 EBF03_06380   Arcanobacterium haemolyticum SCDR 1 QCX47070.1    
 SAMN04489737_0588   Arcanobacterium phocae DSM 10002 SDU78719.1    
 DJ013_03255   Arcticibacterium luteifluviistationis SM1504 AWV97239.1    
 DJ013_02065   Arcticibacterium luteifluviistationis SM1504 AWV97025.1    
 neuraminidase   Arcticibacterium luteifluviistationis SM1504 AWV98504.1    
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