Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); 2-keto-3-deoxynononic acid hydrolase (EC 3.2.1.-); anhydrosialidase (EC 4.2.2.15); 3-deoxy-D-manno-octulosonic-acid hydrolase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (3514); Uniprot accession (686); PDB accession (144); 3D entries (19); cryst (0)
All (3255) Archaea (1) Bacteria (2851) Eukaryota (371) Viruses (32) Structure (19) Characterized (96)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 30 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 MB46_14870   Arthrobacter sp. A3 ALV46586.1    
 AUT26_16850   Arthrobacter sp. ATCC 21022 AMB41684.1    
 AUT26_02815   Arthrobacter sp. ATCC 21022 AMB39271.1    
 AL755_01530   Arthrobacter sp. ERGS1:01 ALE04399.1    
 AL755_20445   Arthrobacter sp. ERGS1:01 ALE07301.1    
 Arth_0189   Arthrobacter sp. FB24 ABK01590.1 A0JRC0  
 Arth_0543   Arthrobacter sp. FB24 ABK01942.1 A0JSC2  
 Arth_1043   Arthrobacter sp. FB24 ABK02437.1 A0JTR7  
 AHiyo8_21250   Arthrobacter sp. Hiyo8 BAS13822.1    
 AHiyo8_41430 (fragment)   Arthrobacter sp. Hiyo8 BAS15840.1    
 AHiyo8_41450 (fragment)   Arthrobacter sp. Hiyo8 BAS15842.1    
 AFL94_13940   Arthrobacter sp. LS16 ALD64846.1    
 ART_3011   Arthrobacter sp. PAMC 25486 AIY02610.1    
 ART_2421   Arthrobacter sp. PAMC 25486 AIY02020.1    
 BWQ92_09865   Arthrobacter sp. QXT-31 APX01975.1    
 ARUE_c36650 (Neda2)   Arthrobacter sp. Rue61a AFR30544.1    
 ARUE_c06020 (Neda1)   Arthrobacter sp. Rue61a AFR27537.1    
 ATC04_01630   Arthrobacter sp. YC-RL1 ALQ29368.1    
 ATC04_04020   Arthrobacter sp. YC-RL1 ALQ29794.1    
 CGK93_03325   Arthrobacter sp. YN ASN18844.1    
 ARZXY2_216   Arthrobacter sp. ZXY-2 AOY69783.1    
 ARZXY2_3332   Arthrobacter sp. ZXY-2 AOY72846.1    
 dqs_0821   Azoarcus olearius DQS4 ANQ83891.1    
 AzCIB_0589   Azoarcus sp. CIB AKU10494.1    
 AZC_1976   Azorhizobium caulinodans ORS 571 BAF87974.1 A8I330  
 AZOBR_p330018   Azospirillum brasilense Sp245 CCD02617.1    
 AZL_b03350   Azospirillum sp. B510 BAI74998.1 D3P2H8  
 BEH_14040   Bacillus endophyticus Hbe603 AKO93101.1    
 BkAM31D_08205 (Nana_1)   Bacillus krulwichiae AM31D ARK29843.1    
 BG04_2545   Bacillus megaterium NBRC 15308 = ATCC 14581 AJI23743.1    
 neuraminidase   Bacillus megaterium Q3 AKP76837.1    
 BaLi_c35650   Bacillus paralicheniformis ATCC 9945a AGN37880.1    
 SC10_B2orf05366   Bacillus paralicheniformis BL-09 AJO19928.1    
 BLMD_17765   Bacillus paralicheniformis MDJK30 ARA87173.1    
 VP59_14385   Bacillus pumilus C4 ANT57950.1    
 BS467_08540   Bacillus pumilus GLB197 APP15773.1    
 ID12_01240   Bacillus pumilus GR-8 AKU30122.1    
 ASM07_14440   Bacillus pumilus ku-bf1 AMB91048.1    
 BW16_16050   Bacillus pumilus MTCC B6033 AHL72811.1    
 AKO65_08050   Bacillus pumilus NJ-M2 ALM27969.1    
 AKO66_04365   Bacillus pumilus NJ-V ANY95985.1    
 AMR71_04360   Bacillus pumilus NJ-V2 ALM44509.1    
 BPUM_2975   Bacillus pumilus SAFR-032 ABV63629.1 A8FHB2  
 BTUAT1_30520   Bacillus pumilus TUAT1 BAT50186.1    
 VT48_15370   Bacillus pumilus W3 AKC67349.1    
 BRL64_15545   Bacillus safensis BRM1 ARD57504.1    
 BSL056_16670   Bacillus safensis KCTC 12796BP APJ12485.1    
 BK049_12160   Bacillus xiamenensis VV3 AOZ89376.1    
 CGC64_15605   Bacteroides caccae ATCC 43185 ASM67226.1    
 CGC64_11165   Bacteroides caccae ATCC 43185 ASM66464.1    
 CGC64_15630   Bacteroides caccae ATCC 43185 ASM67231.1    
 BACCAC_01090 (23295)   Bacteroides caccae ATCC 43185 ZP_01959484.1 A5ZDY0 4Q6K[A,B,C,D]
 A4V03_11370   Bacteroides caecimuris I48 ANU58088.1    
 A4V03_11350   Bacteroides caecimuris I48 ANU58084.1    
 BcellWH2_04061 (Nanb_1)   Bacteroides cellulosilyticus WH2 ALJ61281.1    
 BcellWH2_04931 (Nanb_2)   Bacteroides cellulosilyticus WH2 ALJ62140.1    
 ABI39_09070   Bacteroides dorei CL03T12C01 AND19544.1    
 ABI39_13235   Bacteroides dorei CL03T12C01 AND21950.1    
 ABI39_21340   Bacteroides dorei CL03T12C01 AND21646.1    
 EL88_15630   Bacteroides dorei isolate HS1_L1_B_010 AII64498.1    
 EL88_19225   Bacteroides dorei isolate HS1_L1_B_010 AII65153.1    
 EL88_06210   Bacteroides dorei isolate HS1_L1_B_010 AII62782.1    
 GV66_09220   Bacteroides dorei isolate HS1_L3_B_079 AII67866.1    
 GV66_14125   Bacteroides dorei isolate HS1_L3_B_079 AII68768.1    
 GV66_22035   Bacteroides dorei isolate HS1_L3_B_079 AII70179.1    
 IY41_14770   Bacteroides dorei isolate HS2_L_2_B_045b ALA76192.1    
 IY41_22375   Bacteroides dorei isolate HS2_L_2_B_045b ALA75889.1    
 IY41_09195   Bacteroides dorei isolate HS2_L_2_B_045b ALA73618.1    
 BF638R_4097 (NanH2)   Bacteroides fragilis 638R CBW24534.1 E1WPI1  
 BF638R_1728 (NanH)   Bacteroides fragilis 638R CBW22254.1 E1WUA2  
 BF638R_3784   Bacteroides fragilis 638R CBW24233.1 E1WMX5  
 BF638R_2942   Bacteroides fragilis 638R CBW23425.1 E1WS95  
 BF638R_3785   Bacteroides fragilis 638R CBW24234.1 E1WMX6  
 MB0529_01600   Bacteroides fragilis BE1 CUA18247.1    
 MB0529_03665   Bacteroides fragilis BE1 CUA20274.1    
 MB0529_02769   Bacteroides fragilis BE1 CUA19389.1    
 MB0529_03664 (NedA)   Bacteroides fragilis BE1 CUA20273.1    
 MB0529_03980 (NanH)   Bacteroides fragilis BE1 CUA20564.1    
 VU15_17650   Bacteroides fragilis BOB25 AKA53347.1    
 VU15_13185   Bacteroides fragilis BOB25 AKA52559.1    
 VU15_19555   Bacteroides fragilis BOB25 AKA53665.1    
 VU15_07340   Bacteroides fragilis BOB25 AKA51541.1    
 VU15_17645   Bacteroides fragilis BOB25 AKA53346.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-1 ANG58842.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-10 ANG58849.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-2 ANG58843.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-4 ANG58844.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-8 ANG58847.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-9 ANG58848.1    
 BF1806 (Nanh)   Bacteroides fragilis NCTC 9343 CAH07505.1 Q5LEE6  
 BF3709   Bacteroides fragilis NCTC 9343 CAH09389.1 Q5L943  
 BF4051 (Nanh2)   Bacteroides fragilis NCTC 9343 CAH09725.1 Q5L868  
 AE940_04785   Bacteroides fragilis S14 ANQ60189.1    
 AE940_14190   Bacteroides fragilis S14 ANQ61855.1    
 AE940_10415   Bacteroides fragilis S14 ANQ61181.1    
 AE940_14185   Bacteroides fragilis S14 ANQ61854.1    
 BF3099   Bacteroides fragilis YCH46 BAD49844.1    
 BF3937   Bacteroides fragilis YCH46 BAD50679.1    
 BF4242   Bacteroides fragilis YCH46 BAD50984.1 Q64NE9  
 BF3936   Bacteroides fragilis YCH46 BAD50678.1 Q64PA3  
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