Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (6853); Uniprot accession (682); PDB accession (152); 3D entries (21); cryst (0)
All (6602) Archaea (1) Bacteria (6102) Eukaryota (442) Viruses (50) unclassified (7) Structure (21) Characterized (97)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 63 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 sialidase (NanH) (fragment)   Actinomyces oris R6630 ACH92909.1 B6D580  
 NanH (fragment)   Actinomyces oris S29C ACH92886.1 B6D557  
 NanH (fragment)   Actinomyces oris S47B ACH92889.1 B6D560  
 NanH (fragment)   Actinomyces oris S55N ACH92890.1 B6D561  
 NanH (fragment)   Actinomyces oris S56D ACH92891.1 B6D562  
 NanH (fragment)   Actinomyces oris S62B ACH92893.1 B6D564  
 NanH (fragment)   Actinomyces oris S64C ACH92894.1 B6D565  
 AXE84_02820   Actinomyces oris T14V AMD98486.1    
 AXE84_08015   Actinomyces oris T14V AMD99362.1    
 NanH (fragment)   Actinomyces oris T22P-A1 ACH92874.1 B6D545  
 NanH (fragment)   Actinomyces oris T5P-1 ACH92875.1 B6D546  
 NanH (fragment)   Actinomyces oris T6P-2 ACH92876.1 B6D547  
 NanH (fragment)   Actinomyces oris T8-1 ACH92877.1 B6D548  
 NanH (fragment)   Actinomyces oris U149-1 ACH92895.1 B6D566  
 NanH (fragment)   Actinomyces oris UN4B2c ACH92878.1 B6D549  
 NanH (fragment)   Actinomyces oris W11-1-1 ACH92879.1 B6D550  
 NanH (fragment)   Actinomyces oris WE10B-1 ACH92881.1 B6D552  
 NanH (fragment)   Actinomyces oris WE1Aa1 ACH92882.1 B6D553  
 NanH (fragment)   Actinomyces oris WE3Bc14 ACH92883.1 B6D554  
 NanH (fragment)   Actinomyces oris WE4Bb1 ACH92884.1 B6D555  
 NanH (fragment)   Actinomyces oris WE5Ba2 ACH92885.1 B6D556  
 NanH (fragment)   Actinomyces oris WE8B-23 ACH92904.1 B6D575  
 NanH (fragment)   Actinomyces oris WE9A10-1 ACH92905.1 B6D576  
 CHIBA101_0334   Actinomyces sp. Chiba101 BAW92205.1    
 CHIBA101_0699   Actinomyces sp. Chiba101 BAW92565.1    
 HW274_04415 (fragment)   Actinomyces sp. oral taxon 169 F0496 QLF53089.1    
 HW274_02160   Actinomyces sp. oral taxon 169 F0496 QLF52678.1    
 HW274_09630   Actinomyces sp. oral taxon 169 F0496 QLF54682.1    
 FBF36_09925   Actinomyces sp. oral taxon 171 str. F0337 QCT33734.1    
 FBF36_04650 (fragment)   Actinomyces sp. oral taxon 171 str. F0337 QCT32854.1    
 C3V41_05600   Actinomyces sp. oral taxon 897 F0631 AVM62872.1    
 C3V41_11170   Actinomyces sp. oral taxon 897 F0631 AVM62488.1    
 B6G06_06740   Actinomyces sp. pika_114 ARD42074.1    
 B6G06_08515   Actinomyces sp. pika_114 ARD42376.1    
 HPC72_01130   Actinomyces sp. zg-325 QKD79047.1    
 HPC72_02845   Actinomyces sp. zg-325 QKD79335.1    
 BK816_02270   Actinomyces tangfeifanii VUL4_3 AOZ72269.1    
 BK816_08405   Actinomyces tangfeifanii VUL4_3 AOZ73295.1    
 BK816_02265   Actinomyces tangfeifanii VUL4_3 AOZ72268.1    
 NanH (fragment)   Actinomyces viscosus NCTC10951 ACH92825.1
VEI16517.1
B6D4Z6  
 NCTC10951_00294 (Nana_1)   Actinomyces viscosus NCTC10951 VEI14435.1    
 NCTC10951_01457 (Nana_2)   Actinomyces viscosus NCTC10951 VEI16013.1    
 sialidase (NanH) 3.2.1.18 Actinomyces viscosus T14V AAA21932.1 Q44562  
 L083_3658   Actinoplanes sp. N902-109 AGL17168.1    
 neuraminidase   Actinopolymorpha singaporensis DSM 22024 SDR76605.1    
 SAMN04489717_4474   Actinopolymorpha singaporensis DSM 22024 SDS95315.1    
 FB03_03655   Actinotignum schaalii CCUG 27420 AIE82512.1    
 HUW48_09360   Adhaeribacter sp. KUDC8001 QMU28235.1    
 HUW51_19060   Adhaeribacter swui KCTC 52873 QNF34726.1    
 HUW51_05905   Adhaeribacter swui KCTC 52873 QNF35745.1    
 neuraminidase (fragment)   Aeromonas hydrophila 23-C-23 QBX77138.1    
 neuraminidase   Aeromonas hydrophila LHW39 QIO19395.1    
 AHML_07175 (fragment)   Aeromonas hydrophila ML09-119 AGM43219.1    
 C3B79_1963 (fragment)   Aeromonas hydrophila WCX23 AZU47735.1
QBX72436.1
   
 C3B79_1962 (fragment)   Aeromonas hydrophila WCX23 AZU47734.1    
 M001_012410 (fragment)   Aeromonas veronii Hm21 QMS78693.1    
 At12D13_46370   Agrobacterium fabrum 12D13 AYM65789.1    
 At1D132_47170   Agrobacterium fabrum 1D132 AYM60724.1    
 Atu5072   Agrobacterium fabrum str. C58 AAK90448.2 Q7D3Z4  
 CFBP5473_19955   Agrobacterium larrymoorei CFBP5473 QCJ00204.1    
 Arad_8793   Agrobacterium radiobacter K84 ACM29979.1 B9JJ87  
 B0909_19345   Agrobacterium rhizogenes K599 AQS64435.1    
 EYD00_18880   Agrobacterium sp. 33MFTa1.1 QBJ15507.1    
 AGROH133_12331   Agrobacterium sp. H13-3 ADY66949.1    
 GH983_20245   Agrobacterium sp. MA01 QGG92652.1    
 BSY240_2787   Agrobacterium sp. RAC06 AOG09493.1    
 At12D1_37040   Agrobacterium tumefaciens 12D1 AYM83588.1    
 At15955_35670   Agrobacterium tumefaciens 15955 AYM18552.1    
 DC439_18610   Agrobacterium tumefaciens 183 QAA99776.1    
 CG010_019330   Agrobacterium tumefaciens 186 QDY96320.1    
 At1D1108_36180   Agrobacterium tumefaciens 1D1108 AYM13244.1    
 At1D1460_36340   Agrobacterium tumefaciens 1D1460 AYM07875.1    
 At1D1609_38510   Agrobacterium tumefaciens 1D1609 AVH43901.1    
 AtA6_36350   Agrobacterium tumefaciens A6 AYM69851.1    
 Ach5_36360   Agrobacterium tumefaciens Ach5 AKC09409.1    
 IAI05_18615   Agrobacterium tumefaciens BIM B-1315G QNP81973.1    
 CFBP5499_20015   Agrobacterium tumefaciens CFBP5499 QCL75764.1    
 CFBP5877_19540   Agrobacterium tumefaciens CFBP5877 QCL81324.1    
 CFBP6623_19370   Agrobacterium tumefaciens CFBP6623 QCL91352.1    
 CFBP6624_19280   Agrobacterium tumefaciens CFBP6624 QCM02338.1    
 CFBP7129_19090   Agrobacterium tumefaciens CFBP7129 QCL96348.1    
 EML4_18295   Agrobacterium tumefaciens EML4 QLG24338.1    
 X971_3789   Agrobacterium tumefaciens LBA4213 (Ach5) AHK03646.1    
 AWN88_06295   Agrobacterium tumefaciens S33 AMD57828.1    
 PYTT_2454   Akkermansia glycaniphila SEI00063.1    
 PYTT_0254   Akkermansia glycaniphila SEH72528.1    
 PYTT_1909   Akkermansia glycaniphila SEH94018.1    
 PYTT_0238   Akkermansia glycaniphila SEH72311.1    
 PYTT_0365   Akkermansia glycaniphila SEH74027.1    
 PYTT_0662   Akkermansia glycaniphila SEH77633.1    
 EYB66_06640   Akkermansia muciniphila 139 QBH16966.1    
 EYB66_02170   Akkermansia muciniphila 139 QBH16153.1    
 EYB66_08450   Akkermansia muciniphila 139 QBH17304.1    
 HXS70_02465   Akkermansia muciniphila AK32 QNB42804.1    
 HXS70_08015   Akkermansia muciniphila AK32 QNB43810.1    
 HXS70_09705   Akkermansia muciniphila AK32 QNB44119.1    
 CUB89_10085   Akkermansia muciniphila AMDK-1 AYR28871.1    
 CUB89_02970   Akkermansia muciniphila AMDK-1 AYR27624.1    
 CUB89_08595   Akkermansia muciniphila AMDK-1 AYR28617.1    
 CUC06_03470   Akkermansia muciniphila AMDK-2 AYR34527.1    
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