Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); 2-keto-3-deoxynononic acid hydrolase (EC 3.2.1.-); anhydrosialidase (EC 4.2.2.15); 3-deoxy-D-manno-octulosonic-acid hydrolase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (3514); Uniprot accession (686); PDB accession (144); 3D entries (19); cryst (0)
All (3255) Archaea (1) Bacteria (2851) Eukaryota (371) Viruses (32) Structure (19) Characterized (96)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 30 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AXE84_08015   Actinomyces oris T14V AMD99362.1    
 NanH (fragment)   Actinomyces oris T22P-A1 ACH92874.1 B6D545  
 NanH (fragment)   Actinomyces oris T5P-1 ACH92875.1 B6D546  
 NanH (fragment)   Actinomyces oris T6P-2 ACH92876.1 B6D547  
 NanH (fragment)   Actinomyces oris T8-1 ACH92877.1 B6D548  
 NanH (fragment)   Actinomyces oris U149-1 ACH92895.1 B6D566  
 NanH (fragment)   Actinomyces oris UN4B2c ACH92878.1 B6D549  
 NanH (fragment)   Actinomyces oris W11-1-1 ACH92879.1 B6D550  
 NanH (fragment)   Actinomyces oris WE10B-1 ACH92881.1 B6D552  
 NanH (fragment)   Actinomyces oris WE1Aa1 ACH92882.1 B6D553  
 NanH (fragment)   Actinomyces oris WE3Bc14 ACH92883.1 B6D554  
 NanH (fragment)   Actinomyces oris WE4Bb1 ACH92884.1 B6D555  
 NanH (fragment)   Actinomyces oris WE5Ba2 ACH92885.1 B6D556  
 NanH (fragment)   Actinomyces oris WE8B-23 ACH92904.1 B6D575  
 NanH (fragment)   Actinomyces oris WE9A10-1 ACH92905.1 B6D576  
 CHIBA101_0334   Actinomyces sp. Chiba101 BAW92205.1    
 CHIBA101_0699   Actinomyces sp. Chiba101 BAW92565.1    
 B6G06_06740   Actinomyces sp. pika_114 ARD42074.1    
 B6G06_08515   Actinomyces sp. pika_114 ARD42376.1    
 BK816_02270   Actinomyces sp. VUL4_3 AOZ72269.1    
 BK816_08405   Actinomyces sp. VUL4_3 AOZ73295.1    
 BK816_02265   Actinomyces sp. VUL4_3 AOZ72268.1    
 NanH (fragment)   Actinomyces viscosus NCTC10951 ACH92825.1 B6D4Z6  
 sialidase (NanH) 3.2.1.18 Actinomyces viscosus T14V AAA21932.1 Q44562  
 L083_3658   Actinoplanes sp. N902-109 AGL17168.1    
 neuraminidase   Actinopolymorpha singaporensis DSM 22024 SDR76605.1    
 SAMN04489717_4474   Actinopolymorpha singaporensis DSM 22024 SDS95315.1    
 FB03_03655   Actinotignum schaalii CCUG 27420 AIE82512.1    
 AHML_07175   Aeromonas hydrophila ML09-119 AGM43219.1    
 Atu5072   Agrobacterium fabrum str. C58 AAK90448.2 Q7D3Z4  
 Arad_8793   Agrobacterium radiobacter K84 ACM29979.1 B9JJ87  
 B0909_19345   Agrobacterium rhizogenes K599 AQS64435.1    
 AGROH133_12331   Agrobacterium sp. H13-3 ADY66949.1    
 BSY240_2787   Agrobacterium sp. RAC06 AOG09493.1    
 Ach5_36360   Agrobacterium tumefaciens Ach5 AKC09409.1    
 X971_3789   Agrobacterium tumefaciens LBA4213 (Ach5) AHK03646.1    
 AWN88_06295   Agrobacterium tumefaciens S33 AMD57828.1    
 PYTT_2454   Akkermansia glycaniphila SEI00063.1    
 PYTT_0254   Akkermansia glycaniphila SEH72528.1    
 PYTT_1207   Akkermansia glycaniphila SEH85134.1    
 PYTT_1909   Akkermansia glycaniphila SEH94018.1    
 PYTT_0238   Akkermansia glycaniphila SEH72311.1    
 PYTT_0365   Akkermansia glycaniphila SEH74027.1    
 PYTT_0662   Akkermansia glycaniphila SEH77633.1    
 Amuc_1547   Akkermansia muciniphila ATCC BAA-835 ACD05368.1    
 Amuc_0623   Akkermansia muciniphila ATCC BAA-835 ACD04460.1    
 Amuc_0625   Akkermansia muciniphila ATCC BAA-835 ACD04462.1 B2UPI5  
 Amuc_1835   Akkermansia muciniphila ATCC BAA-835 ACD05653.1 B2UN42  
 A4V05_03295   Akkermansia muciniphila YL44 ANU60534.1
ASB36178.1
   
 A4V05_05020   Akkermansia muciniphila YL44 ANU60847.1
ANU60847.2
ASB34341.1
   
 A4V05_10410   Akkermansia muciniphila YL44 ANU61810.1
ASB35300.1
   
 A4V05_10420   Akkermansia muciniphila YL44 ANU61812.1
ANU61812.2
ASB35302.1
   
 ABO_1915   Alcanivorax borkumensis SK2 CAL17363.1 Q0VN85  
 B5T_01121   Alcanivorax dieselolei B5 MCCC 1A00001 AFT69404.1    
 S7S_13465   Alcanivorax pacificus W11-5 AJD49105.1    
 CEK62_21655   Alcanivorax sp. N3-7A ASK36962.1    
 CEK62_01460   Alcanivorax sp. N3-7A ASK33144.1    
 AS19_19780   Alcanivorax sp. NBRC 101098 BAP14829.1    
 P40_05315   Alcanivorax xenomutans P40 ARB44919.1    
 neuraminidase   Algoriphagus sp. M8-2 AMQ58104.1    
 AO498_15680   Algoriphagus sp. M8-2 AMQ57894.1    
 AO498_15700   Algoriphagus sp. M8-2 AMQ57898.1    
 ORF   Alloactinosynnema sp. L-07 CRK56629.1    
 SAMN04489726_7712   Allokutzneria albata DSM 44149 SDN67662.1    
 AJAP_24045   Amycolatopsis japonica MG417-CF17 AIG77658.1    
 SAMN04489733_2798   Amycolatopsis keratiniphila FH 1893 SDU29546.1    
 neuraminidase   Amycolatopsis lurida NRRL 2430 AJK58915.1    
 neuraminidase   Amycolatopsis mediterranei RB AGT84773.1    
 neuraminidase   Amycolatopsis mediterranei S699 AEK42715.1
AFO77645.1
   
 AMED_4157 (Neu)   Amycolatopsis mediterranei U32 ADJ45934.1 D8HR32  
 neuraminidase   Amycolatopsis methanolica 239 AIJ25416.1    
 neuraminidase   Amycolatopsis orientalis B-37 ANN16941.1    
 AORI_5269   Amycolatopsis orientalis HCCB10007 AGM07852.1    
 BEQ56_05740   Anaerolineaceae bacterium oral taxon 439 W11661 AOH43019.1    
 ANTHELSMS3_04479   Antarctobacter heliothermus SMS3 ASP23079.1    
 neuraminidase   Aquiflexum balticum DSM 16537 SMD43125.1    
 SAMN00777080_0072   Aquiflexum balticum DSM 16537 SMD41548.1    
 Arch_0026   Arcanobacterium haemolyticum DSM 20595 ADH91794.1 D7BLJ5  
 Arch_1299   Arcanobacterium haemolyticum DSM 20595 ADH93004.1 D7BK24  
 SAMN04489737_0588   Arcanobacterium phocae DSM 10002 SDU78719.1    
 AREALGSMS7_01722   Arenibacter algicola SMS7 ASO05189.1    
 AREALGSMS7_04073   Arenibacter algicola SMS7 ASO07479.1    
 AREALGSMS7_02634   Arenibacter algicola SMS7 ASO06076.1    
 AREALGSMS7_01259   Arenibacter algicola SMS7 ASO04734.1    
 AREALGSMS7_02035   Arenibacter algicola SMS7 ASO05493.1    
 AREALGSMS7_00159   Arenibacter algicola SMS7 ASO03657.1    
 AREALGSMS7_04071   Arenibacter algicola SMS7 ASO07477.1    
 AREALGSMS7_00756   Arenibacter algicola SMS7 ASO04237.1    
 CCB80_03445   Armatimonadetes bacterium Uphvl-Ar1 ARU40244.1    
 CCB81_05240   Armatimonadetes bacterium Uphvl-Ar2 ARU43592.1    
 CCB81_08930   Armatimonadetes bacterium Uphvl-Ar2 ARU44263.1    
 AS189_01530   Arthrobacter alpinus ERGS4:06 ALO65417.1    
 AS189_03795   Arthrobacter alpinus ERGS4:06 ALO65774.1    
 AOC05_00520   Arthrobacter alpinus R3.8 ALE93860.1    
 AOC05_14270   Arthrobacter alpinus R3.8 ALE93219.1    
 CGQ24_09500   Arthrobacter sp. 7749 ASN39227.1    
 CGQ24_17515   Arthrobacter sp. 7749 ASN40620.1    
 CGQ24_01955   Arthrobacter sp. 7749 ASN37889.1    
 MB46_00650   Arthrobacter sp. A3 ALV44242.1    
 MB46_17180   Arthrobacter sp. A3 ALV46955.1    
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