Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (5863); Uniprot accession (681); PDB accession (152); 3D entries (21); cryst (0)
All (5623) Archaea (1) Bacteria (5166) Eukaryota (415) Viruses (35) unclassified (6) Structure (21) Characterized (97)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 53 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 OJF2_54060 (Neda_1)   Aquisphaera giovannonii OJF2 QEH36821.1    
 OJF2_59800   Aquisphaera giovannonii OJF2 QEH37389.1    
 FSB73_06770   Arachidicoccus ginsenosidivorans Gsoil 809 QEC74209.1    
 E0W69_015090   Arachidicoccus sp. B3-10 QES90995.1    
 E0W69_008005   Arachidicoccus sp. B3-10 QES88603.1    
 D6B99_08590   Arachidicoccus sp. KIS59-12 AYD47657.1    
 D6B99_12625   Arachidicoccus sp. KIS59-12 AYD48371.1    
 Arch_0026   Arcanobacterium haemolyticum DSM 20595 ADH91794.1 D7BLJ5  
 Arch_1299   Arcanobacterium haemolyticum DSM 20595 ADH93004.1 D7BK24  
 NCTC8452_00740 (Neda_2)   Arcanobacterium haemolyticum NCTC8452 SQH28241.1    
 NCTC8452_00161 (Neda_1)   Arcanobacterium haemolyticum NCTC8452 SQH27393.1    
 EBF03_00135   Arcanobacterium haemolyticum SCDR 1 QCX45996.1    
 EBF03_06380   Arcanobacterium haemolyticum SCDR 1 QCX47070.1    
 SAMN04489737_0588   Arcanobacterium phocae DSM 10002 SDU78719.1    
 DJ013_03255   Arcticibacterium luteifluviistationis SM1504 AWV97239.1    
 DJ013_02065   Arcticibacterium luteifluviistationis SM1504 AWV97025.1    
 neuraminidase   Arcticibacterium luteifluviistationis SM1504 AWV98504.1    
 AREALGSMS7_01722   Arenibacter algicola SMS7 ASO05189.1    
 AREALGSMS7_04073   Arenibacter algicola SMS7 ASO07479.1    
 AREALGSMS7_02634   Arenibacter algicola SMS7 ASO06076.1    
 AREALGSMS7_01259   Arenibacter algicola SMS7 ASO04734.1    
 AREALGSMS7_02035   Arenibacter algicola SMS7 ASO05493.1    
 AREALGSMS7_00159   Arenibacter algicola SMS7 ASO03657.1    
 AREALGSMS7_00756   Arenibacter algicola SMS7 ASO04237.1    
 CCB80_03445   Armatimonadetes bacterium Uphvl-Ar1 ARU40244.1    
 AS189_01530   Arthrobacter alpinus ERGS4:06 ALO65417.1    
 AS189_03795   Arthrobacter alpinus ERGS4:06 ALO65774.1    
 AOC05_00520   Arthrobacter alpinus R3.8 ALE93860.1    
 AOC05_14270   Arthrobacter alpinus R3.8 ALE93219.1    
 FCN77_06040   Arthrobacter sp. 24S4-2 QCO97358.1    
 CGQ24_09500   Arthrobacter sp. 7749 ASN39227.1    
 CGQ24_17515   Arthrobacter sp. 7749 ASN40620.1    
 CGQ24_01955   Arthrobacter sp. 7749 ASN37889.1    
 MB46_00650   Arthrobacter sp. A3 ALV44242.1    
 MB46_17180   Arthrobacter sp. A3 ALV46955.1    
 MB46_14870   Arthrobacter sp. A3 ALV46586.1    
 AUT26_16850   Arthrobacter sp. ATCC 21022 AMB41684.1    
 AUT26_02815   Arthrobacter sp. ATCC 21022 AMB39271.1    
 AL755_01530   Arthrobacter sp. ERGS1:01 ALE04399.1    
 AL755_20445   Arthrobacter sp. ERGS1:01 ALE07301.1    
 Arth_0189   Arthrobacter sp. FB24 ABK01590.1 A0JRC0  
 Arth_0543   Arthrobacter sp. FB24 ABK01942.1 A0JSC2  
 Arth_1043   Arthrobacter sp. FB24 ABK02437.1 A0JTR7  
 AHiyo8_21250   Arthrobacter sp. Hiyo8 BAS13822.1    
 AHiyo8_41430 (fragment)   Arthrobacter sp. Hiyo8 BAS15840.1    
 AHiyo8_41450 (fragment)   Arthrobacter sp. Hiyo8 BAS15842.1    
 AFL94_13940   Arthrobacter sp. LS16 ALD64846.1    
 ART_3011   Arthrobacter sp. PAMC 25486 AIY02610.1    
 ART_2421   Arthrobacter sp. PAMC 25486 AIY02020.1    
 E5206_02800   Arthrobacter sp. PAMC25564 QCB95995.1    
 CFN17_11605   Arthrobacter sp. PM3 AXJ10195.1    
 BWQ92_09865   Arthrobacter sp. QXT-31 APX01975.1    
 ARUE_c36650 (Neda2)   Arthrobacter sp. Rue61a AFR30544.1    
 ARUE_c06020 (Neda1)   Arthrobacter sp. Rue61a AFR27537.1    
 ATC04_01630   Arthrobacter sp. YC-RL1 ALQ29368.1    
 ATC04_04020   Arthrobacter sp. YC-RL1 ALQ29794.1    
 CGK93_03325   Arthrobacter sp. YN ASN18844.1    
 ARZXY2_216   Arthrobacter sp. ZXY-2 AOY69783.1    
 ARZXY2_3332   Arthrobacter sp. ZXY-2 AOY72846.1    
 NCTC3438_00966 (Nana_2) (fragment)   Avibacterium volantium NCTC3438 VEB23405.1    
 CEW87_02730   Azoarcus communis TSNA42 AWI78361.1    
 CEW83_11575   Azoarcus communis TSPY31 AWI75773.1    
 dqs_0821   Azoarcus olearius DQS4 ANQ83891.1    
 AzCIB_0589   Azoarcus sp. CIB AKU10494.1    
 CJ010_04635 (fragment)   Azoarcus sp. DD4 QDF95879.1    
 AZC_1976   Azorhizobium caulinodans ORS 571 BAF87974.1 A8I330  
 AZSP09_29290   Azospira sp. I09 BBN89906.1    
 D3869_31025   Azospirillum brasilense MTCC4039 QCO19864.1    
 AZOBR_p330018   Azospirillum brasilense Sp245 CCD02617.1
AWJ93376.1
   
 AZL_b03350   Azospirillum sp. B510 BAI74998.1 D3P2H8  
 DEW08_19540   Azospirillum sp. CFH 70021 AWK88289.1    
 TSH58p_32145   Azospirillum sp. TSH58 AWJ88258.1    
 BAE_03450   Bacillus aerophilus 232 QAR51893.1    
 D0438_06225   Bacillus altitudinis Cr2-1 QDZ94545.1    
 BPGQ101_16250   Bacillus altitudinis GQYP101 QCU20340.1    
 CSE15_15515   Bacillus altitudinis P-10 ATP95260.1    
 CFN77_15955   Bacillus altitudinis SGAir0031 ATH73633.1    
 BEH_14040   Bacillus endophyticus Hbe603 AKO93101.1    
 COP00_20425   Bacillus glycinifermentans KBN06P03352 ATH94656.1    
 BkAM31D_08205 (Nana_1)   Bacillus krulwichiae AM31D ARK29843.1    
 NCTC4824_03972 (Nana_1)   Bacillus lentus NCTC4824 SQI63205.1    
 neuraminidase   Bacillus licheniformis NCTC8721 VEB20675.1    
 CEQ83_09155   Bacillus megaterium QFY72678.1    
 EQG57_01360   Bacillus megaterium NBRC 15308 = ATCC 14581 QCY23316.1    
 BG04_2545   Bacillus megaterium NBRC 15308 = ATCC 14581 AJI23743.1    
 neuraminidase   Bacillus megaterium Q3 AKP76837.1    
 C2I28_17160   Bacillus megaterium YC4-R4 AWD66690.1    
 FLQ07_01930   Bacillus paralicheniformis A4-3 QEO04450.1    
 BaLi_c35650   Bacillus paralicheniformis ATCC 9945a AGN37880.1    
 SC10_B2orf05366   Bacillus paralicheniformis BL-09 AJO19928.1    
 D5285_18720   Bacillus paralicheniformis CBMAI 1303 AYQ17947.1    
 BLMD_17765   Bacillus paralicheniformis MDJK30 ARA87173.1    
 VP59_14385   Bacillus pumilus C4 ANT57950.1    
 BS467_08540   Bacillus pumilus GLB197 APP15773.1    
 ID12_01240   Bacillus pumilus GR-8 AKU30122.1    
 ASM07_14440   Bacillus pumilus ku-bf1 AMB91048.1    
 BW16_16050   Bacillus pumilus MTCC B6033 AHL72811.1    
 AKO65_08050   Bacillus pumilus NJ-M2 ALM27969.1    
 AKO66_04365   Bacillus pumilus NJ-V ANY95985.1    
 AMR71_04360   Bacillus pumilus NJ-V2 ALM44509.1    
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