Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (6164); Uniprot accession (681); PDB accession (152); 3D entries (21); cryst (0)
All (5923) Archaea (1) Bacteria (5447) Eukaryota (425) Viruses (36) unclassified (14) Structure (21) Characterized (97)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 56 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 C1I88_08450 (fragment)   Akkermansia muciniphila EB-AMDK-7 QAA36920.1    
 C1I90_08625   Akkermansia muciniphila EB-AMDK-8 QAA39295.1    
 C1I90_10365   Akkermansia muciniphila EB-AMDK-8 QAA39604.1    
 C1I90_03780   Akkermansia muciniphila EB-AMDK-8 QAA38454.1    
 SI90_03070   Akkermansia muciniphila H2 QAR49693.1    
 SI90_00160   Akkermansia muciniphila H2 QAR49252.1    
 AKMU_06700   Akkermansia muciniphila JCM 30893 BBP47924.1    
 AKMU_19910   Akkermansia muciniphila JCM 30893 BBP49245.1    
 AKMU_16410   Akkermansia muciniphila JCM 30893 BBP48895.1    
 A4V05_03295   Akkermansia muciniphila YL44 ANU60534.1
ASB36178.1
   
 A4V05_05020   Akkermansia muciniphila YL44 ANU60847.1
ANU60847.2
ASB34341.1
   
 A4V05_10420   Akkermansia muciniphila YL44 ANU61812.1
ANU61812.2
ASB35302.1
   
 ABO_1915   Alcanivorax borkumensis SK2 CAL17363.1 Q0VN85  
 B5T_01121   Alcanivorax dieselolei B5 MCCC 1A00001 AFT69404.1    
 S7S_13465   Alcanivorax pacificus W11-5 AJD49105.1    
 CEK62_21655   Alcanivorax sp. N3-2A ASK36962.1    
 CEK62_01460   Alcanivorax sp. N3-2A ASK33144.1    
 AS19_19780   Alcanivorax sp. NBRC 101098 BAP14829.1    
 P40_05315   Alcanivorax xenomutans P40 ARB44919.1    
 neuraminidase   Algoriphagus sanaruensis M8-2 AMQ58104.1    
 AO498_15680   Algoriphagus sanaruensis M8-2 AMQ57894.1    
 AO498_15700   Algoriphagus sanaruensis M8-2 AMQ57898.1    
 Sialidase (Hz136) 3.2.1.18 Alistipes     6MNJ[A,B]
6MNJ[A]
 neuraminidase (NanH)   Alistipes dispar 5CPEGH6 BBL05903.1    
 neuraminidase   Alistipes sp. dk3624 QGA22782.1    
 ORF   Alloactinosynnema sp. L-07 CRK56629.1    
 SAMN04489726_7712   Allokutzneria albata DSM 44149 SDN67662.1    
 C7Y71_004285   Alloprevotella sp. E39 QFQ12292.1    
 C7Y71_008080   Alloprevotella sp. E39 QFQ12979.1    
 C7Y71_011050   Alloprevotella sp. E39 QFQ13500.1    
 neuraminidase   Aminobacter sp. MSH1 AWC21155.1    
 A4R43_01560   Amycolatopsis albispora WP1 AXB41369.1    
 A4R43_04030   Amycolatopsis albispora WP1 AXB41796.1    
 A4R43_06755   Amycolatopsis albispora WP1 AXB42267.1    
 A4R43_37780   Amycolatopsis albispora WP1 AXB47503.1    
 AJAP_24045   Amycolatopsis japonica MG417-CF17 AIG77658.1    
 SAMN04489733_2798   Amycolatopsis keratiniphila FH 1893 SDU29546.1    
 neuraminidase   Amycolatopsis lurida NRRL 2430 AJK58915.1    
 neuraminidase   Amycolatopsis mediterranei RB AGT84773.1    
 neuraminidase   Amycolatopsis mediterranei S699 AEK42715.1
AFO77645.1
   
 AMED_4157 (Neu)   Amycolatopsis mediterranei U32 ADJ45934.1 D8HR32  
 neuraminidase   Amycolatopsis methanolica 239 AIJ25416.1    
 neuraminidase   Amycolatopsis orientalis B-37 ANN16941.1    
 AORI_5269   Amycolatopsis orientalis HCCB10007 AGM07852.1    
 CU254_13445   Amycolatopsis sp. AA4 ATY11350.1    
 CU254_27865   Amycolatopsis sp. AA4 ATY16653.1    
 neuraminidase   Amycolatopsis sp. BJA-103 AUI58079.1    
 YIM_15935 (Neda1)   Amycolatopsis sp. YIM 10 QFU88368.1    
 YIM_40265 (Neda3)   Amycolatopsis sp. YIM 10 QFU93192.1    
 YIM_20280 (Neda2)   Amycolatopsis sp. YIM 10 QFU89235.1    
 YIM_17095   Amycolatopsis sp. YIM 10 QFU88599.1    
 STSP2_00340 (Neda_1)   Anaerohalosphaera lusitana ST-NAGAB-D1 AQT67197.1    
 STSP2_01847 (Neda_5)   Anaerohalosphaera lusitana ST-NAGAB-D1 AQT68677.1    
 STSP2_01342 (Neda_2)   Anaerohalosphaera lusitana ST-NAGAB-D1 AQT68187.1    
 STSP2_01343 (Neda_3)   Anaerohalosphaera lusitana ST-NAGAB-D1 AQT68188.1    
 BEQ56_05740   Anaerolineaceae bacterium oral taxon 439 W11661 AOH43019.1    
 FRZ59_15220   Anseongella ginsenosidimutans Gsoil 524 QEC54313.1    
 FRZ59_00935   Anseongella ginsenosidimutans Gsoil 524 QEC54117.1    
 FRZ59_09625   Anseongella ginsenosidimutans Gsoil 524 QEC52569.1    
 FRZ59_08645   Anseongella ginsenosidimutans Gsoil 524 QEC52394.1    
 FRZ59_08475   Anseongella ginsenosidimutans Gsoil 524 QEC52363.1    
 FRZ59_08610   Anseongella ginsenosidimutans Gsoil 524 QEC52387.1    
 FRZ59_08680   Anseongella ginsenosidimutans Gsoil 524 QEC52400.1    
 ANTHELSMS3_04479   Antarctobacter heliothermus SMS3 ASP23079.1    
 neuraminidase   Aquiflexum balticum DSM 16537 SMD43125.1    
 SAMN00777080_0072   Aquiflexum balticum DSM 16537 SMD41548.1    
 OJF2_74540 (Neda_2)   Aquisphaera giovannonii OJF2 QEH38844.1    
 OJF2_54060 (Neda_1)   Aquisphaera giovannonii OJF2 QEH36821.1    
 OJF2_59800   Aquisphaera giovannonii OJF2 QEH37389.1    
 FSB73_06770   Arachidicoccus ginsenosidivorans Gsoil 809 QEC74209.1    
 E0W69_015090   Arachidicoccus sp. B3-10 QES90995.1    
 E0W69_008005   Arachidicoccus sp. B3-10 QES88603.1    
 D6B99_08590   Arachidicoccus sp. KIS59-12 AYD47657.1    
 D6B99_12625   Arachidicoccus sp. KIS59-12 AYD48371.1    
 Arch_0026   Arcanobacterium haemolyticum DSM 20595 ADH91794.1 D7BLJ5  
 Arch_1299   Arcanobacterium haemolyticum DSM 20595 ADH93004.1 D7BK24  
 NCTC8452_00740 (Neda_2)   Arcanobacterium haemolyticum NCTC8452 SQH28241.1    
 NCTC8452_00161 (Neda_1)   Arcanobacterium haemolyticum NCTC8452 SQH27393.1    
 EBF03_00135   Arcanobacterium haemolyticum SCDR 1 QCX45996.1    
 EBF03_06380   Arcanobacterium haemolyticum SCDR 1 QCX47070.1    
 SAMN04489737_0588   Arcanobacterium phocae DSM 10002 SDU78719.1    
 DJ013_03255   Arcticibacterium luteifluviistationis SM1504 AWV97239.1    
 DJ013_02065   Arcticibacterium luteifluviistationis SM1504 AWV97025.1    
 neuraminidase   Arcticibacterium luteifluviistationis SM1504 AWV98504.1    
 AREALGSMS7_01722   Arenibacter algicola SMS7 ASO05189.1    
 AREALGSMS7_04073   Arenibacter algicola SMS7 ASO07479.1    
 AREALGSMS7_02634   Arenibacter algicola SMS7 ASO06076.1    
 AREALGSMS7_01259   Arenibacter algicola SMS7 ASO04734.1    
 AREALGSMS7_02035   Arenibacter algicola SMS7 ASO05493.1    
 AREALGSMS7_00159   Arenibacter algicola SMS7 ASO03657.1    
 AREALGSMS7_00756   Arenibacter algicola SMS7 ASO04237.1    
 CCB80_03445   Armatimonadetes bacterium Uphvl-Ar1 ARU40244.1    
 AS189_01530   Arthrobacter alpinus ERGS4:06 ALO65417.1    
 AS189_03795   Arthrobacter alpinus ERGS4:06 ALO65774.1    
 AOC05_00520   Arthrobacter alpinus R3.8 ALE93860.1    
 AOC05_14270   Arthrobacter alpinus R3.8 ALE93219.1    
 FCN77_06040   Arthrobacter sp. 24S4-2 QCO97358.1    
 CGQ24_09500   Arthrobacter sp. 7749 ASN39227.1    
 CGQ24_17515   Arthrobacter sp. 7749 ASN40620.1    
 CGQ24_01955   Arthrobacter sp. 7749 ASN37889.1    
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