Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (4271); Uniprot accession (686); PDB accession (146); 3D entries (19); cryst (0)
All (3963) Archaea (1) Bacteria (3547) Eukaryota (381) Viruses (34) Structure (19) Characterized (96)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 37 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 BF638R_3785   Bacteroides fragilis 638R CBW24234.1 E1WMX6  
 MB0529_01600   Bacteroides fragilis BE1 CUA18247.1    
 MB0529_03665   Bacteroides fragilis BE1 CUA20274.1    
 MB0529_02769   Bacteroides fragilis BE1 CUA19389.1    
 MB0529_03664 (NedA)   Bacteroides fragilis BE1 CUA20273.1    
 MB0529_03980 (NanH)   Bacteroides fragilis BE1 CUA20564.1    
 VU15_17650   Bacteroides fragilis BOB25 AKA53347.1    
 VU15_13185   Bacteroides fragilis BOB25 AKA52559.1    
 VU15_19555   Bacteroides fragilis BOB25 AKA53665.1    
 VU15_07340   Bacteroides fragilis BOB25 AKA51541.1    
 VU15_17645   Bacteroides fragilis BOB25 AKA53346.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-1 ANG58842.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-10 ANG58849.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-2 ANG58843.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-4 ANG58844.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-8 ANG58847.1    
 neuraminidase (NanH) (fragment)   Bacteroides fragilis IQS-9 ANG58848.1    
 BF1806 (Nanh)   Bacteroides fragilis NCTC 9343 CAH07505.1 Q5LEE6  
 BF3709   Bacteroides fragilis NCTC 9343 CAH09389.1 Q5L943  
 BF4051 (Nanh2)   Bacteroides fragilis NCTC 9343 CAH09725.1 Q5L868  
 BUN20_11375   Bacteroides fragilis Q1F2 AUI49199.1    
 BUN20_05835   Bacteroides fragilis Q1F2 AUI46163.1    
 AE940_04785   Bacteroides fragilis S14 ANQ60189.1    
 AE940_14190   Bacteroides fragilis S14 ANQ61855.1    
 AE940_10415   Bacteroides fragilis S14 ANQ61181.1    
 AE940_14185   Bacteroides fragilis S14 ANQ61854.1    
 BF3099   Bacteroides fragilis YCH46 BAD49844.1    
 BF3937   Bacteroides fragilis YCH46 BAD50679.1    
 BF4242   Bacteroides fragilis YCH46 BAD50984.1 Q64NE9  
 BF3936   Bacteroides fragilis YCH46 BAD50678.1 Q64PA3  
 sialidase (BF1729) 3.2.1.18 Bacteroides fragilis YCH46 BAA05853.1
AAA22912.1
BAC56895.1
BAC56895.2
BAD48476.1
P31206
P31206
 
 Bache_2784   Bacteroides helcogenes P 36-108 ADV44727.1    
 Bache_1478   Bacteroides helcogenes P 36-108 ADV43483.1    
 Bache_2002   Bacteroides helcogenes P 36-108 ADV43976.1    
 C3V43_10350   Bacteroides heparinolyticus F0111 AVM58107.1    
 C3V43_10330 (fragment)   Bacteroides heparinolyticus F0111 AVM58103.1    
 Bovatus_01543 (Neda_2)   Bacteroides ovatus ATCC 8483 ALJ46187.1    
 Bovatus_01539 (Neda_1)   Bacteroides ovatus ATCC 8483 ALJ46183.1    
 Bovatus_00599 (NanB)   Bacteroides ovatus ATCC 8483 ALJ45265.1    
 Bovatus_00310   Bacteroides ovatus ATCC 8483 ALJ44981.1    
 Bovatus_04939 (Pkn1_3)   Bacteroides ovatus ATCC 8483 ALJ49526.1    
 BACOV975_03113 (NanH)   Bacteroides ovatus V975 SCV09319.1    
 BACOV975_04337   Bacteroides ovatus V975 SCV10543.1    
 BACOV975_03396   Bacteroides ovatus V975 SCV09602.1    
 BACOV975_04333   Bacteroides ovatus V975 SCV10539.1    
 BACOV975_02744   Bacteroides ovatus V975 SCV08950.1    
 Bacsa_2222   Bacteroides salanitronis DSM 18170 ADY36775.1    
 Bacsa_3464   Bacteroides salanitronis DSM 18170 ADY37989.1    
 Btheta7330_02628 (NanB)   Bacteroides thetaiotaomicron 7330 ALJ42170.1    
 Btheta7330_02907   Bacteroides thetaiotaomicron 7330 ALJ42444.1    
 bimodular α-1,5-rhamnosidase / α-2,3-KDO-hydrolase (BT1013) 3.2.1.40
3.2.1.-
Bacteroides thetaiotaomicron VPI-5482 AAO76120.1
NP_809926.1
Q8A904  
 sialidase (BtsA;BTSA;BT0455) 3.2.1.18 Bacteroides thetaiotaomicron VPI-5482 AAO75562.1
NP_809368.1
Q8AAK9 4BBW[A]
 BVU_1801   Bacteroides vulgatus ATCC 8482 ABR39477.1 A6L1B3  
 BVU_2645   Bacteroides vulgatus ATCC 8482 ABR40297.1 A6L3N3  
 BVU_4143   Bacteroides vulgatus ATCC 8482 ABR41745.1 A6L7T1  
 BvMPK_2334   Bacteroides vulgatus mpk ALK84931.1    
 BvMPK_0225   Bacteroides vulgatus mpk ALK82864.1    
 BvMPK_3663   Bacteroides vulgatus mpk ALK86224.1    
 BXY_44750   Bacteroides xylanisolvens XB1A CBK69352.1 D6D4V8  
 BXY_06360   Bacteroides xylanisolvens XB1A CBK65853.1 D6D758  
 BXY_09340   Bacteroides xylanisolvens XB1A CBK66099.1 D6D7V4  
 BXY_44710   Bacteroides xylanisolvens XB1A CBK69348.1 D6D4V4  
 C4H11_09345   Bacteroides zoogleoformans ATCC 33285 AVM54056.1    
 C4H11_13210   Bacteroides zoogleoformans ATCC 33285 AVM54135.1    
 BARVI_04125   Barnesiella viscericola DSM 18177 AHF12110.1    
 BARVI_05470   Barnesiella viscericola DSM 18177 AHF12313.1    
 Belba_3245   Belliella baltica DSM 15883 AFL85755.1    
 D521_0592   beta proteobacterium CB AGG33161.1    
 Bcav_1436   Beutenbergia cavernae DSM 12333 ACQ79694.1 C5C2K8  
 Bcav_1440   Beutenbergia cavernae DSM 12333 ACQ79698.1 C5C2L2  
 BBBF_1781 (fragment)   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ98988.1    
 BBBF_1780 (fragment)   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ98987.1    
 BBBF_1585   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ98792.1    
 BBBF_1779   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ98986.1    
 RY70_1745   Bifidobacterium bifidum BF3 ALE12069.1    
 RY70_1956   Bifidobacterium bifidum BF3 ALE12272.1    
 BBB_1792 (NedA)   Bifidobacterium bifidum BGN4 AFL05382.1    
 BBB_1574   Bifidobacterium bifidum BGN4 AFL05165.1    
 BBB_1791   Bifidobacterium bifidum BGN4 AFL05381.1    
 exo-α-sialidase (SiaBb2;BBP_0054) 3.2.1.18 Bifidobacterium bifidum JCM 1254 BAK26854.1    
 sialidase (Siabb1)   Bifidobacterium bifidum JCM 1254 BAN14906.1    
 BBJK_01327   Bifidobacterium bifidum LMG 13195 JCM 7004 BBA47922.1    
 BBJK_00867   Bifidobacterium bifidum LMG 13195 JCM 7004 BBA47625.1    
 BBJK_01326   Bifidobacterium bifidum LMG 13195 JCM 7004 BBA47921.1    
 BBNG_01507   Bifidobacterium bifidum NCIMB 41171 EFR50959.1    
 BBPR_1793   Bifidobacterium bifidum PRL2010 ADP36806.1 E4P0F8  
 BBPR_1794   Bifidobacterium bifidum PRL2010 ADP36807.1 E4P0F9  
 BBPR_1596   Bifidobacterium bifidum PRL2010 ADP36622.1    
 BBIF_1734   Bifidobacterium bifidum S17 ADO53939.1 E3ERD5  
 BBIF_1733   Bifidobacterium bifidum S17 ADO53938.1 E3ERD4  
 BBIF_1538   Bifidobacterium bifidum S17 ADO53743.1    
 BBTM_01956   Bifidobacterium bifidum TMC 3115 BBA56221.1    
 BBTM_01414   Bifidobacterium bifidum TMC 3115 BBA55846.1    
 BBTM_01954   Bifidobacterium bifidum TMC 3115 BBA56220.1    
 BB017W439_0171   Bifidobacterium breve 017W439 AUD94497.1    
 BB082W48_0178   Bifidobacterium breve 082W48 AUD96425.1    
 B12L_0154   Bifidobacterium breve 12L AHJ14956.1    
 BB139W423_0183   Bifidobacterium breve 139W423 AUD98320.1    
 BB180W83_0170   Bifidobacterium breve 180W83 AUE00317.1    
 BB215W447A_0177   Bifidobacterium breve 215W447a AUE02216.1    
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