Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); 2-keto-3-deoxynononic acid hydrolase (EC 3.2.1.-); anhydrosialidase (EC 4.2.2.15); 3-deoxy-D-manno-octulosonic-acid hydrolase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (3514); Uniprot accession (686); PDB accession (144); 3D entries (19); cryst (0)
All (3255) Archaea (1) Bacteria (2851) Eukaryota (371) Viruses (32) Structure (19) Characterized (96)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 30 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 sialidase (BF1729) 3.2.1.18 Bacteroides fragilis YCH46 BAA05853.1
AAA22912.1
BAC56895.1
BAC56895.2
BAD48476.1
P31206
P31206
 
 Bache_2784   Bacteroides helcogenes P 36-108 ADV44727.1    
 Bache_1478   Bacteroides helcogenes P 36-108 ADV43483.1    
 Bache_2002   Bacteroides helcogenes P 36-108 ADV43976.1    
 Bovatus_01543 (Neda_2)   Bacteroides ovatus ATCC 8483 ALJ46187.1    
 Bovatus_01539 (Neda_1)   Bacteroides ovatus ATCC 8483 ALJ46183.1    
 Bovatus_00599 (NanB)   Bacteroides ovatus ATCC 8483 ALJ45265.1    
 Bovatus_00310   Bacteroides ovatus ATCC 8483 ALJ44981.1    
 Bovatus_04939 (Pkn1_3)   Bacteroides ovatus ATCC 8483 ALJ49526.1    
 BACOV975_03113 (NanH)   Bacteroides ovatus V975 SCV09319.1    
 BACOV975_04337   Bacteroides ovatus V975 SCV10543.1    
 BACOV975_03396   Bacteroides ovatus V975 SCV09602.1    
 BACOV975_04333   Bacteroides ovatus V975 SCV10539.1    
 BACOV975_02744   Bacteroides ovatus V975 SCV08950.1    
 Bacsa_2222   Bacteroides salanitronis DSM 18170 ADY36775.1    
 Bacsa_3464   Bacteroides salanitronis DSM 18170 ADY37989.1    
 Btheta7330_02628 (NanB)   Bacteroides thetaiotaomicron 7330 ALJ42170.1    
 Btheta7330_02907   Bacteroides thetaiotaomicron 7330 ALJ42444.1    
 bimodular α-1,5-rhamnosidase / α-2,3-KDO-hydrolase (BT1013) 3.2.1.40
3.2.1.-
Bacteroides thetaiotaomicron VPI-5482 AAO76120.1
NP_809926.1
Q8A904  
 sialidase (BtsA;BTSA;BT0455) 3.2.1.18 Bacteroides thetaiotaomicron VPI-5482 AAO75562.1
NP_809368.1
Q8AAK9 4BBW[A]
 BVU_1801   Bacteroides vulgatus ATCC 8482 ABR39477.1 A6L1B3  
 BVU_2645   Bacteroides vulgatus ATCC 8482 ABR40297.1 A6L3N3  
 BVU_4143   Bacteroides vulgatus ATCC 8482 ABR41745.1 A6L7T1  
 BvMPK_2334   Bacteroides vulgatus mpk ALK84931.1    
 BvMPK_0225   Bacteroides vulgatus mpk ALK82864.1    
 BvMPK_3663   Bacteroides vulgatus mpk ALK86224.1    
 BXY_44750   Bacteroides xylanisolvens XB1A CBK69352.1 D6D4V8  
 BXY_06360   Bacteroides xylanisolvens XB1A CBK65853.1 D6D758  
 BXY_09340   Bacteroides xylanisolvens XB1A CBK66099.1 D6D7V4  
 BXY_44710   Bacteroides xylanisolvens XB1A CBK69348.1 D6D4V4  
 BARVI_04125   Barnesiella viscericola DSM 18177 AHF12110.1    
 BARVI_05470   Barnesiella viscericola DSM 18177 AHF12313.1    
 Belba_3245   Belliella baltica DSM 15883 AFL85755.1    
 D521_0592   beta proteobacterium CB AGG33161.1    
 Bcav_1436   Beutenbergia cavernae DSM 12333 ACQ79694.1 C5C2K8  
 Bcav_1440   Beutenbergia cavernae DSM 12333 ACQ79698.1 C5C2L2  
 BBBF_1781 (fragment)   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ98988.1    
 BBBF_1780 (fragment)   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ98987.1    
 BBBF_1585   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ98792.1    
 BBBF_1779   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ98986.1    
 RY70_1745   Bifidobacterium bifidum BF3 ALE12069.1    
 RY70_1956   Bifidobacterium bifidum BF3 ALE12272.1    
 BBB_1792 (NedA)   Bifidobacterium bifidum BGN4 AFL05382.1    
 BBB_1574   Bifidobacterium bifidum BGN4 AFL05165.1    
 BBB_1791   Bifidobacterium bifidum BGN4 AFL05381.1    
 exo-α-sialidase (SiaBb2;BBP_0054) 3.2.1.18 Bifidobacterium bifidum JCM 1254 BAK26854.1    
 sialidase (Siabb1)   Bifidobacterium bifidum JCM 1254 BAN14906.1    
 BBJK_01327   Bifidobacterium bifidum LMG 13195 JCM 7004 BBA47922.1    
 BBJK_00867   Bifidobacterium bifidum LMG 13195 JCM 7004 BBA47625.1    
 BBJK_01326   Bifidobacterium bifidum LMG 13195 JCM 7004 BBA47921.1    
 BBNG_01507   Bifidobacterium bifidum NCIMB 41171 EFR50959.1    
 BBPR_1793   Bifidobacterium bifidum PRL2010 ADP36806.1 E4P0F8  
 BBPR_1794   Bifidobacterium bifidum PRL2010 ADP36807.1 E4P0F9  
 BBPR_1596   Bifidobacterium bifidum PRL2010 ADP36622.1    
 BBIF_1734   Bifidobacterium bifidum S17 ADO53939.1 E3ERD5  
 BBIF_1733   Bifidobacterium bifidum S17 ADO53938.1 E3ERD4  
 BBIF_1538   Bifidobacterium bifidum S17 ADO53743.1    
 B12L_0154   Bifidobacterium breve 12L AHJ14956.1    
 B689b_0150   Bifidobacterium breve 689b AHJ22233.1    
 HMPREF9228_0182   Bifidobacterium breve ACS-071-V-Sch8b AEF27628.1    
 RY69_1874   Bifidobacterium breve BR3 ALE14100.1    
 BBBR_0147   Bifidobacterium breve DSM 20213 = JCM 1192 BAQ99185.1    
 B7017_0178   Bifidobacterium breve JCM 7017 AHJ16734.1    
 B7019_0163   Bifidobacterium breve JCM 7019 AHJ18498.1    
 BBL520_00915   Bifidobacterium breve LMC520 AQM42305.1    
 B2258_0149   Bifidobacterium breve NCFB 2258 AHJ20399.1    
 BS27_0176   Bifidobacterium breve S27 AHJ24071.1    
 Bbr_0171   Bifidobacterium breve UCC2003 ABE94880.1    
 SAMN04489749_2042   Bifidobacterium longum Su859 SDO69221.1    
 α-2,6- / α-2,3-sialidase (NanH1;Blon_0646) 3.2.1.- Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 ACJ51753.1 B7GPM3  
 α-2,6- / α-2,3-sialidase (NanH2;Blon_2348) 3.2.1.- Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 ACJ53406.1 B7GNQ0  
 BLIJ_2422   Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 BAJ69999.1    
 BLIJ_0651   Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 BAJ68244.1    
 RY67_485   Bifidobacterium longum subsp. infantis BT1 ALE08548.1    
 RY67_1368   Bifidobacterium longum subsp. infantis BT1 ALE09388.1    
 BBSC_2316   Bifidobacterium scardovii JCM 12489 = DSM 13734 BAQ32396.1    
 ADH70_012315   Blautia coccoides YL58 ASU31741.1    
 CGC63_00200   Blautia hansenii DSM 20583 ASM68050.1    
 A4V09_13825   Blautia sp. YL58 ANU76745.1
ANU76745.2
   
 BHK69_21185   Bosea vaviloviae Vaf18 AOO82623.1    
 Bfae_08290   Brachybacterium faecium DSM 4810 ACU84683.1 C7M9Y9  
 Bfae_08300   Brachybacterium faecium DSM 4810 ACU84684.1 C7M9Z0  
 BH708_17940   Brachybacterium sp. P6-10-X1 APX34274.1    
 BH708_17935   Brachybacterium sp. P6-10-X1 APX34273.1    
 BHAMNSH16_00850   Brachyspira hampsonii NSH-16 ASJ20283.1    
 Bmur_1914   Brachyspira murdochii DSM 12563 ADG71993.1 D5UBC0  
 Bmur_2712   Brachyspira murdochii DSM 12563 ADG72779.1 D5U755  
 neuraminidase   Brachyspira pilosicoli 95/1000 ADK30921.1 D8ICP8  
 neuraminidase   Brachyspira pilosicoli 95/1000 ADK32000.1 D8IFS7  
 neuraminidase   Brachyspira pilosicoli B2904 AFR69790.1    
 neuraminidase   Brachyspira pilosicoli B2904 AFR71142.1    
 neuraminidase   Brachyspira pilosicoli B2904 AFR71144.1    
 BPP43_05040   Brachyspira pilosicoli P43/6/78 AGA66268.1    
 BPP43_05045   Brachyspira pilosicoli P43/6/78 AGA66269.1    
 BPP43_10460   Brachyspira pilosicoli P43/6/78 AGA67264.1    
 neuraminidase   Brachyspira pilosicoli WesB CCG56392.1    
 neuraminidase   Brachyspira pilosicoli WesB CCG56394.1    
 WESB_2245   Brachyspira pilosicoli WesB CCG57707.1    
 RN69_34380   Bradyrhizobium japonicum E109 AJA64834.1    
 BKD09_RS37450   Bradyrhizobium japonicum J5 APG14055.1    
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