Glycoside Hydrolase Family 136

Activities in FamilyLacto-N-biosidase (Lewis antigen a/b specificity) (EC 3.2.1.-);
Lacto-N-biosidase (EC 3.2.1.140);
Mechanism Retaining e
3D Structure Statusparallel β-helix
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorAsp
NoteCreated after Yamada et al. (2017) Cell Chem Biol 24:515-524 (PMID=28392148)
External resourcesCAZypedia;
Statistics GenBank accession (1161); Uniprot accession (7); PDB accession (7); 3D entries (4); cryst (0)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 NOV99_09830   Streptococcus suis 2018WUSS151 UUD28565.1    
 AN924_08950   Streptococcus suis 90-1330 AMU79403.1    
 SSU98_0212   Streptococcus suis 98HAH33 ABP91370.1    
 SSUA7_0200   Streptococcus suis A7 AER43535.1    
 SSUBM407_0194   Streptococcus suis BM407 CAZ55026.1    
 CR541_01170   Streptococcus suis CS100322 AUW23203.1    
 SSUD9_0216   Streptococcus suis D9 AER16484.1    
 JZ789_01235   Streptococcus suis GX69 UCS85032.1    
 SSGZ1_0196   Streptococcus suis GZ1 ADE30661.1    
 CR542_01175   Streptococcus suis HA0609 AUW25209.1    
 FPT06_04075   Streptococcus suis INT-01 QDS23520.1    
 DK235_01180   Streptococcus suis ISU1606 QLL44534.1    
 DK877_01175   Streptococcus suis ISU2414 QLL52630.1    
 DK875_10080   Streptococcus suis ISU2514 QLL50162.1    
 DK237_01165   Streptococcus suis ISU2614 QLL46496.1    
 DK878_01135   Streptococcus suis ISU2660 QLL54711.1    
 DK876_01180   Streptococcus suis ISU2714 QLL50686.1    
 A7J09_10400   Streptococcus suis ISU2812 ASW52477.1    
 SSUJS14_0206   Streptococcus suis JS14 ADV69313.1    
 A9494_01150   Streptococcus suis LSM102 ARX89668.1    
 L3X06_01110   Streptococcus suis LSM157 UJX23277.1    
 GRI05_01155   Streptococcus suis LSM178 QOJ56372.1    
 L3X15_01110   Streptococcus suis LSM29 UJX21367.1    
 NCTC10234_00219   Streptococcus suis NCTC10234 SQG99888.1    
 AA105_01170   Streptococcus suis NSUI002 ALA27928.1    
 APQ97_10040   Streptococcus suis NSUI060 AML47367.1    
 SSU0201   Streptococcus suis P1/7 CAR44524.1    
 YYK_00910   Streptococcus suis S735 AFQ99702.1    
 NJAUSS_0215   Streptococcus suis SC070731 AGG63709.1    
 B9H01_01175   Streptococcus suis SC19 ARL69213.1    
 SSUSC84_0192   Streptococcus suis SC84 CAZ50970.1    
 DP111_01190   Streptococcus suis SH1510 AXI64734.1    
 SSU12_0204   Streptococcus suis SS12 AER14401.1    
 BVD85_01030   Streptococcus suis SS2-1 AUW21199.1    
 SSUST3_0217   Streptococcus suis ST3 AEB80693.1    
 NLY35_01155   Streptococcus suis STC104 UTH71326.1    
 NKZ79_01155   Streptococcus suis STC78 UTH54519.1    
 NKZ64_01155   Streptococcus suis STC80 UTH56619.1    
 NKZ66_01155   Streptococcus suis STC81 UTH58724.1    
 NKZ67_01155   Streptococcus suis STC83 UTH60824.1    
 NKZ65_01155   Streptococcus suis STC84 UTH62930.1    
 NKZ80_01155   Streptococcus suis STC85 UTH65023.1    
 NKZ81_01155   Streptococcus suis STC86 UTH67126.1    
 NKZ63_01155   Streptococcus suis STC90 UTH69228.1    
 K8227_01120   Streptococcus suis SZ1908 UAM76234.1    
 T15_0196   Streptococcus suis T15 AGZ22309.1    
 NLY75_01130   Streptococcus suis T15 UTI57440.1    
 K6967_01115   Streptococcus suis Transconjugant cAKJ18 QZT31680.1    
 K6971_01115   Streptococcus suis Transconjugant cDY107 QZT25514.1    
 K6970_01115   Streptococcus suis Transconjugant cFJSM5 QZT21746.1    
 K6968_01115   Streptococcus suis Transconjugant cNJ3 QZT19852.1    
 K6975_01115   Streptococcus suis Transconjugant cSS389 QZT23615.1    
 NOV96_09630   Streptococcus suis WUSS030 UYZ66073.1    
 YB51_1025   Streptococcus suis YB51 AGW86577.1    
 I5W22_01110   Streptococcus suis YP20190405 QPO28943.1    
 ZY05719_01130   Streptococcus suis ZY05719 AKG39638.1    
 K1J60_00430   Streptomyces akebiae MG28 QYX75179.1    
 SLNHY_0983   Streptomyces albus BK3-25 AOU75674.1    
 SLNWT_0982   Streptomyces albus DSM 41398 AJE81358.1    
 DUI70_0973   Streptomyces albus ZD11 AYN31476.1    
 OG771_36320   Streptomyces anulatus NBC_01421 WUY08742.1    
 G9272_41635   Streptomyces asoensis H2S5 QJT06032.1    
 P6B95_27940   Streptomyces atratus MJM3502 WPW30830.1    
 C5746_25155   Streptomyces atratus SCSIO_ZH16 AXE79661.1    
 SU9_027685   Streptomyces auratus AGR0001 QTZ94766.1    
 SBI_01801   Streptomyces bingchenggensis BCW-1 ADI04922.1    
 SBI_09784   Streptomyces bingchenggensis BCW-1 ADI12902.1    
 I6J39_33815   Streptomyces californicus FDAARGOS_1209 QRV32373.1    
 I6J40_00195   Streptomyces californicus FDAARGOS_1210 QRV58744.1    
 I6J41_33755   Streptomyces californicus FDAARGOS_1211 QRV45792.1    
 I6J42_00265   Streptomyces californicus FDAARGOS_1212 QRV38475.1    
 I6J43_33380   Streptomyces californicus FDAARGOS_1213 QRV52467.1    
 IHE65_44440   Streptomyces caniscabiei ID-03-3A WEO29655.1    
 OG925_14420   Streptomyces canus NBC_01585 WSD85416.1    
 OG925_44695   Streptomyces canus NBC_01585 WSD90973.1    
 QU709_44215   Streptomyces coralus SX92 WLW57955.1    
 N8I84_00565   Streptomyces cynarae HUAS 13-4 UXY17433.1    
 BN159_0696   Streptomyces davaonensis JCM 4913 CCK25075.1    
 L3078_02810   Streptomyces deccanensis KCTC 19241 ULR48298.1    
 NEH16_02175   Streptomyces drozdowiczii MDA8-470 UZK53086.1    
 M4V62_36095   Streptomyces durmitorensis MS405 UQT60044.1    
 RI138_29635   Streptomyces durocortorensis C11-1 WNF31474.1    
 OJ254_24740   Streptomyces endophytica HNM0140 UZJ32911.1    
 F0344_01815   Streptomyces finlayi NBSH44 QNE79018.1    
 J4032_05255   Streptomyces formicae 1H-GS9 UNM11002.1    
 KY5_3676   Streptomyces formicae KY5 ATL28694.1    
 SGFS_008220   Streptomyces graminofaciens A-8890 BBC29528.1    
 AVL59_28165   Streptomyces griseochromogenes ATCC 14511 ANP56832.1    
 DWG14_08201   Streptomyces griseorubiginosus 3E-1 AYC43893.1    
 CEB94_04295   Streptomyces hawaiiensis ATCC 12236 QCD54167.1    
 SHXM_00569   Streptomyces hygroscopicus XM201 AQW47106.1    
 KI385_40085 (fragment)   Streptomyces inhibens NRRL30439 UKY54405.1    
 CP970_23905   Streptomyces kanamyceticus ATCC 12853 QEU93545.1    
 KJK29_33985   Streptomyces koelreuteriae MG62 QWB27206.1    
 P8A22_02525   Streptomyces laculatispora Mut2 WLQ38999.1    
 P8A22_15195   Streptomyces laculatispora Mut2 WLQ41216.1    
 SLA_4631   Streptomyces laurentii ATCC 31255 BAU85515.1    
 GJU35_03755   Streptomyces lincolnensis B48 QMV04856.1    
 GJU35_02925   Streptomyces lincolnensis B48 QMV04721.1    
 SLCG_0702   Streptomyces lincolnensis LC-G AXG51857.1    
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